EKS-CAJ-00235

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00235

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	383.6	1.0E-114	73	369	297

Status

Unreviewed

Ensembl Protein

ENSCJAP00000027831

UniProt Accession

F7GNM2;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K2

Gene Synonyms/Alias

MAP2K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000015084	ENSCJAP00000027826	ENSCJAT00000029405
ENSCJAG00000015084	ENSCJAP00000027833	ENSCJAT00000029412
ENSCJAG00000015084	ENSCJAP00000027831	ENSCJAT00000029410

Organism

Callithrix jacchus

Functional Description

Protein Length

400

Protein Sequence
(FASTA)

MLARRKPVLP ALTINPAIAE GPSPTSEGAS EANLVDLQKK LEELELDEQQ KKRLEAFLTQ 60

KAKVGELKDD DFERISELGA GNGGVVTKVQ HRPSGLIMAR KLIHLEIKPA IRNQIIRELQ 120

VLHECNSPYI VGFYGAFYSD GEISICMEHM DGGSLDQVLK EAKRIPEEIL GKVSIAVLRG 180

LAYLREKHQI MHRDVKPSNI LVNSRGEIKL CDFGVSGQLI DSMANSFVGT RSYMAPERLQ 240

GTHYSVQSDI WSMGLSLVEL AIGRYPIPPP DAKELEAIFG RPVVDGAEGE PHSISPRPRP 300

PGRPMSGHGM DSRPAMAIFE LLDYIVNEPP PKLPNGVFTP DFQEFVNRCL IKNPAERADL 360

KMLTNHAFIK RSEVEEVDFA GWLCKTLRLN QPSTPTRTAV 400

Nucleotide Sequence
(FASTA)

ATGCTGGCCC GGAGGAAGCC GGTGCTGCCG GCGCTCACCA TCAACCCTGC CATCGCCGAG 60

GGCCCGTCCC CCACCAGCGA GGGCGCCTCT GAGGCAAACC TGGTGGACCT GCAGAAGAAG 120

CTAGAGGAGC TGGAACTTGA TGAGCAGCAG AAGAAGCGGC TGGAAGCCTT CCTCACCCAG 180

AAAGCCAAGG TCGGCGAACT CAAAGACGAT GACTTTGAGA GGATCTCGGA GCTGGGCGCA 240

GGCAACGGCG GCGTGGTCAC CAAGGTCCAA CACAGACCCT CGGGCCTTAT CATGGCCCGG 300

AAGCTGATCC ACCTGGAGAT CAAGCCGGCC ATCCGGAACC AGATCATCCG AGAGCTGCAG 360

GTCCTGCATG AGTGCAACTC CCCCTACATC GTGGGCTTCT ACGGGGCCTT CTACAGCGAC 420

GGGGAGATCA GCATCTGCAT GGAGCACATG GATGGCGGCT CCCTGGACCA GGTGCTGAAA 480

GAGGCCAAGA GGATTCCCGA GGAGATCCTG GGGAAAGTCA GCATTGCGGT GCTCCGGGGC 540

TTGGCGTACC TCCGAGAGAA GCACCAGATC ATGCACCGAG ATGTGAAGCC TTCCAACATC 600

CTGGTGAACT CCAGAGGGGA GATCAAGCTG TGCGACTTTG GGGTGAGCGG GCAGCTCATC 660

GACTCCATGG CCAACTCCTT CGTGGGGACA CGCTCCTACA TGGCTCCGGA GCGGTTGCAG 720

GGCACGCACT ACTCCGTGCA GTCGGACATC TGGAGCATGG GCCTGTCCCT GGTGGAGCTG 780

GCCATCGGGA GGTACCCCAT CCCCCCGCCT GACGCCAAGG AGCTGGAGGC CATCTTTGGT 840

CGGCCCGTGG TCGACGGAGC AGAAGGAGAG CCTCACAGCA TCTCACCTCG GCCGAGACCC 900

CCTGGGCGCC CCATGAGCGG TCACGGGATG GACAGCCGAC CTGCCATGGC CATCTTTGAA 960

CTGCTGGACT ATATTGTGAA TGAGCCGCCT CCCAAGCTGC CCAACGGTGT GTTCACCCCG 1020

GACTTCCAGG AGTTTGTCAA TAGATGCCTC ATCAAGAACC CAGCGGAGCG GGCGGACCTG 1080

AAGATGCTCA CGAACCACGC CTTCATCAAG CGGTCCGAGG TGGAAGAAGT GGATTTTGCT 1140

GGCTGGTTGT GTAAAACCCT GCGGCTGAAC CAGCCCAGCA CACCCACGCG CACTGCCGTG 1200

TGA 1203

Domain Profile

S: 2     ekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyiv  61

         e+++elGaGnggvV+kv+h++sg i+a+K i+leik+++++qi+rel+vl+++ nspyiv

Q: 73    ERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPYIV  131

         789**************************************************.******

S: 62    kfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkek  121

         +fyGaf+s+g++sicme+mdg+sld+vlk+    +kripe++lgk+++av+++l+yl+ek

Q: 132   GFYGAFYSDGEISICMEHMDGGSLDQVLKE----AKRIPEEILGKVSIAVLRGLAYLREK  187

         *****************************9....79************************

S: 122   lkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsv  181

         ++i+HRDvKPsNiLvns+Ge+KlCDFGvsgql+ds+A+s+vGt+sYmaPEr++g ++Ysv

Q: 188   HQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQG-THYSV  246

         ******************************************************.*****

S: 182   ksdvWslGltlvelatgrypyeklke..................................  207

         +sd+Ws+Gl+lvela+gryp++++++

Q: 247   QSDIWSMGLSLVELAIGRYPIPPPDAkeleaifgrpvvdgaegephsisprprppgrpms  306

         ************************999*********************************

S: 208   ...........ilellkaivneeppklpeeefseefqefvskClkkdekeRpklkellkh  256

                    i+ell++ivne+ppklp+  f+++fqefv++Cl+k+++eR++lk+l++h

Q: 307   ghgmdsrpamaIFELLDYIVNEPPPKLPNGVFTPDFQEFVNRCLIKNPAERADLKMLTNH  366

         ************************************************************

S: 257   afi  259

afi

Q: 367   AFI  369

*97

Domain Sequence
(FASTA)

ERISELGAGN GGVVTKVQHR PSGLIMARKL IHLEIKPAIR NQIIRELQVL HECNSPYIVG 60

FYGAFYSDGE ISICMEHMDG GSLDQVLKEA KRIPEEILGK VSIAVLRGLA YLREKHQIMH 120

RDVKPSNILV NSRGEIKLCD FGVSGQLIDS MANSFVGTRS YMAPERLQGT HYSVQSDIWS 180

MGLSLVELAI GRYPIPPPDA KELEAIFGRP VVDGAEGEPH SISPRPRPPG RPMSGHGMDS 240

RPAMAIFELL DYIVNEPPPK LPNGVFTPDF QEFVNRCLIK NPAERADLKM LTNHAFI 297

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013