EKS-CAJ-00150

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00150

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Csk	473.8	2.0E-142	144	389	246

Status

Unreviewed

Ensembl Protein

ENSCJAP00000028523

UniProt Accession

F6QS08;

Protein Name

Protein Synonyms/Alias

Gene Name

CSK

Gene Synonyms/Alias

CSK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000015430	ENSCJAP00000028523	ENSCJAT00000030139
ENSCJAG00000015430	ENSCJAP00000028539	ENSCJAT00000030157
ENSCJAG00000015430	ENSCJAP00000043142	ENSCJAT00000061639
ENSCJAG00000015430	ENSCJAP00000045245	ENSCJAT00000063194

Organism

Callithrix jacchus

Functional Description

Protein Length

399

Protein Sequence
(FASTA)

MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII 60

PANYVQKREG VKAGTKLSLM PKYHDKLSID EEVYFENLMQ LVEHYTSDAD GLCTRLIKPK 120

VMEGTVAAQD EFYRSGWALN MKELKLLQTI GKGEFGDVML GDYRGNKVAV KCIKNDATAQ 180

AFLAEASVMT QLRHSNLVQL LGVIVEEKGG LYIVTEYMAK GSLVDYLRSR GRSVLGGDCL 240

LKFSLDVCEA MEYLESNNFV HRDLAARNVL VSEDNVAKVS DFGLTKEASS TQDTGKLPVK 300

WTAPEALREK KFSTKSDVWS FGILLWEIYS FGRVPYPRIP LKDVVPRVEK GYKMDAPDGC 360

PPAVYEVMKN CWHLDAATRP SFLQLREQLE HIKTHELRL 399

Nucleotide Sequence
(FASTA)

ATGTCAGCAA TACAGGCCGC TTGGCCATCC GGTACAGAAT GTATTGCCAA GTACAACTTC 60

CATGGCACTG CCGAGCAGGA CCTGCCCTTC TGCAAAGGAG ACGTGCTCAC CATTGTGGCC 120

GTCACCAAGG ACCCGAACTG GTACAAAGCC AAAAACAAGG TGGGCCGTGA GGGCATCATC 180

CCAGCCAACT ACGTTCAGAA GCGGGAGGGT GTGAAGGCGG GTACCAAACT CAGCCTCATG 240

CCGAAGTACC ACGACAAGCT CAGCATCGAC GAGGAGGTGT ACTTCGAGAA CCTCATGCAG 300

CTGGTGGAGC ACTACACCTC AGATGCAGAT GGACTCTGTA CGCGCCTCAT CAAACCAAAG 360

GTCATGGAGG GCACGGTGGC GGCCCAGGAT GAGTTCTACC GCAGTGGCTG GGCCCTGAAC 420

ATGAAGGAGC TGAAGCTGCT GCAAACCATC GGGAAGGGGG AGTTTGGAGA CGTGATGCTG 480

GGTGATTACC GAGGGAACAA AGTCGCTGTC AAGTGCATTA AGAACGATGC CACCGCCCAA 540

GCCTTCCTGG CTGAAGCCTC GGTCATGACG CAACTGCGGC ACAGCAACCT GGTGCAGCTC 600

CTGGGCGTGA TCGTGGAGGA GAAGGGTGGG CTCTACATCG TCACTGAGTA CATGGCCAAG 660

GGGAGCCTCG TGGACTACCT GCGGTCTCGG GGTCGGTCAG TGCTGGGCGG AGACTGTCTC 720

CTGAAATTCT CGCTAGACGT CTGCGAGGCC ATGGAATACC TGGAGAGCAA CAACTTCGTG 780

CATCGAGACC TAGCTGCCCG CAACGTGCTG GTGTCTGAGG ACAACGTGGC CAAGGTCAGC 840

GACTTTGGTC TCACCAAGGA GGCTTCCAGC ACCCAGGACA CGGGCAAGCT GCCAGTCAAG 900

TGGACAGCCC CCGAGGCCCT GAGAGAGAAG AAATTCTCCA CCAAGTCTGA TGTGTGGAGT 960

TTTGGAATCC TTCTCTGGGA AATCTACTCC TTCGGGCGAG TGCCTTATCC AAGAATTCCC 1020

CTGAAGGACG TCGTCCCTCG GGTGGAGAAG GGCTACAAGA TGGACGCCCC CGACGGCTGC 1080

CCACCCGCAG TCTACGAGGT CATGAAGAAC TGCTGGCACC TGGATGCCGC CACGCGGCCC 1140

TCCTTCCTGC AGCTCCGAGA GCAGCTTGAG CACATCAAAA CCCACGAGCT GCGCCTGTGA 1200

Domain Profile

S: 1     lklgetigkgefgdvllgeyrgekvavkvikndataqafldeasvmtklehenlvkllgv  60

         lkl +tigkgefgdv+lg+yrg+kvavk+ikndataqafl+easvmt+l+h+nlv+llgv

Q: 144   LKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGV  203

         6899********************************************************

S: 61    ileek.glylvteyvakgslvdylrsrgrallekkqllkfaldvaegmeyleskklvhrd  119

         i+eek gly+vtey+akgslvdylrsrgr++l+ ++llkf+ldv+e+meyles+++vhrd

Q: 204   IVEEKgGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLESNNFVHRD  263

         *****99*****************************************************

S: 120   laarnvlvsedlvakvsdfglakeeskdldsgklpvkwtapealkekkfstksdvwsfgi  179

         laarnvlvsed+vakvsdfgl+ke+s+++d+gklpvkwtapeal+ekkfstksdvwsfgi

Q: 264   LAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGI  323

         ************************************************************

S: 180   llweifsfgrvpypriplkdvvkavekgykmeapegcppevyelmkeaweleaakrpsfa  239

         llwei+sfgrvpypriplkdvv++vekgykm+ap+gcpp+vye+mk++w+l+aa+rpsf

Q: 324   LLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSFL  383

         ************************************************************

S: 240   klkekl  245

         +l+e+l

Q: 384   QLREQL  389

         ***997

Domain Sequence
(FASTA)

LKLLQTIGKG EFGDVMLGDY RGNKVAVKCI KNDATAQAFL AEASVMTQLR HSNLVQLLGV 60

IVEEKGGLYI VTEYMAKGSL VDYLRSRGRS VLGGDCLLKF SLDVCEAMEY LESNNFVHRD 120

LAARNVLVSE DNVAKVSDFG LTKEASSTQD TGKLPVKWTA PEALREKKFS TKSDVWSFGI 180

LLWEIYSFGR VPYPRIPLKD VVPRVEKGYK MDAPDGCPPA VYEVMKNCWH LDAATRPSFL 240

QLREQL 246

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR001452	; SH3_domain.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.
PF00018	; SH3_1; 1.

SMARTs

SM00252	; SH2; 1.
SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50001	; SH2; 1.
PS50002	; SH3; 1.

Prints

PR00401	; SH2DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013