EKS-CAJ-00497

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00497

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TBCK	428.2	1.8E-128	18	273	256

Status

Unreviewed

Ensembl Protein

ENSCJAP00000046748

UniProt Accession

F7HSE3;

Protein Name

Protein Synonyms/Alias

Gene Name

TBCK

Gene Synonyms/Alias

TBCK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000015822	ENSCJAP00000029220	ENSCJAT00000030877
ENSCJAG00000015822	ENSCJAP00000029232	ENSCJAT00000030890
ENSCJAG00000015822	ENSCJAP00000046748	ENSCJAT00000063432
ENSCJAG00000015822	ENSCJAP00000029238	ENSCJAT00000030896

Organism

Callithrix jacchus

Functional Description

Protein Length

661

Protein Sequence
(FASTA)

MFPLKDAEMG AFTFFASALP HDVCGSNGLP LTPNSIKILG RFQILKTITH PRLCQYVDIS 60

RGKHERLVVV AEHCERSLED LLRERKPVSC STVLCIAFEV LQGLQYMNKH GIVHRALSPH 120

NILLDRKGHI KLAKFGLYHM TAHGDDVDFP IGYPSYLAPE VIAQGIFKTT DHMSSKKPLP 180

SGPKSDVWSL GIILFELCVG RKLFQSLDIS ERLKFLLTLD CVDDTLTVLA EEHGCLDIIK 240

ELPKTAIDLL KKCLTFHPSK RLTPDELMKD KVFSEVSPLY THFTKPASLF SSSLRCADLT 300

LPEDISQLCK DITNDYLAER SIEEVYYLWC LAGGDLEKEL VNKEIIRSKP PICTLPNFLF 360

EDGESFGQGR DRSSLLDDTT VTLSLCQLRN RLKDVGGEAF YPLLEDDQSN LPHSNSNNEL 420

SAAATLPLII REKDTEYQLN RIILFDRLLK AYPYKKNQIW KEARVDIPPL MRGLTWAALL 480

GVEGAIHAKY DAIDKDTPIP TDRQIEVDIP RCHQYDELLS SPEGHAKFRR VLKAWVVSHP 540

DLVYWQGLDS LCAPFLYLNF NNEALAYACM SAFIPKYLYN FFLKDNSHVI QEYLTVFSQM 600

IAFHDPELSN HLNEIGFIPD VSTWCVTRTC LIFKIYKMLF KQWKRKEINN KSYLLGDGVA 660

V 661

Nucleotide Sequence
(FASTA)

ATGTTTCCCT TGAAGGATGC TGAAATGGGA GCCTTTACCT TCTTTGCCTC GGCTCTGCCA 60

CATGATGTTT GTGGAAGCAA TGGGCTTCCT CTCACACCAA ATTCCATCAA AATTTTAGGT 120

CGCTTTCAAA TCCTTAAAAC CATCACCCAT CCCAGACTGT GCCAGTATGT GGATATTTCT 180

AGGGGAAAGC ATGAACGACT AGTGGTTGTG GCTGAACATT GTGAACGCAG TCTGGAAGAC 240

TTGCTTCGAG AAAGGAAACC TGTGAGCTGT TCAACAGTTT TGTGCATAGC ATTTGAGGTT 300

CTTCAGGGCT TGCAGTATAT GAACAAACAT GGTATAGTAC ACAGGGCATT GTCTCCTCAT 360

AATATCCTGT TGGACCGAAA GGGACATATT AAATTGGCTA AATTTGGACT TTATCACATG 420

ACAGCTCATG GTGATGATGT TGATTTCCCA ATAGGATATC CCTCATACTT GGCCCCTGAG 480

GTAATTGCAC AGGGAATTTT CAAAACCACT GATCACATGT CAAGTAAAAA ACCATTGCCT 540

TCTGGCCCCA AATCAGATGT ATGGTCTCTT GGAATCATTT TATTTGAGCT TTGTGTGGGA 600

AGAAAATTAT TTCAGAGCTT GGATATTTCC GAAAGACTAA AATTTTTGCT TACTTTGGAT 660

TGTGTAGATG ACACTTTAAC AGTTTTGGCT GAGGAGCATG GTTGTCTGGA CATTATAAAG 720

GAGCTTCCTA AAACTGCGAT AGATCTTTTG AAGAAATGTC TCACCTTCCA TCCTTCTAAG 780

AGGCTAACCC CAGATGAATT AATGAAGGAC AAAGTTTTCA GTGAGGTGTC ACCTTTATAT 840

ACCCACTTTA CCAAACCTGC CAGTCTGTTT TCATCTTCTC TGAGATGTGC TGATTTAACT 900

CTGCCTGAGG ATATCAGTCA GTTGTGTAAA GATATAACCA ATGATTACCT GGCAGAAAGA 960

TCTATTGAAG AAGTTTATTA CCTTTGGTGT TTGGCTGGAG GTGACTTGGA GAAAGAGCTT 1020

GTCAACAAGG AAATCATTCG ATCTAAACCA CCTATCTGCA CACTCCCCAA TTTTCTCTTT 1080

GAGGATGGTG AAAGCTTTGG ACAAGGTCGA GATAGAAGCT CACTTTTAGA TGATACCACT 1140

GTGACATTGT CATTATGCCA GCTAAGAAAT AGATTGAAAG ATGTTGGTGG AGAAGCATTT 1200

TACCCATTAC TTGAAGATGA CCAGTCTAAT TTACCTCATT CAAACAGCAA TAATGAGTTG 1260

TCTGCAGCTG CCACTCTCCC TTTAATCATC AGAGAGAAGG ACACAGAGTA CCAACTAAAC 1320

AGAATTATTC TCTTTGACAG GCTGCTAAAG GCTTATCCAT ATAAAAAAAA CCAAATCTGG 1380

AAAGAAGCAA GAGTTGACAT TCCTCCTCTT ATGAGAGGTT TAACCTGGGC TGCTCTTCTG 1440

GGAGTTGAGG GAGCTATTCA TGCCAAGTAC GACGCAATTG ATAAAGACAC TCCAATTCCT 1500

ACAGATAGAC AAATTGAAGT GGATATTCCT CGCTGTCATC AGTACGATGA ACTGTTATCA 1560

TCACCAGAAG GTCATGCAAA ATTTAGGCGT GTATTAAAAG CCTGGGTAGT GTCTCATCCT 1620

GATCTTGTGT ATTGGCAAGG TCTTGACTCA CTTTGTGCTC CATTCCTTTA TCTAAACTTC 1680

AATAATGAAG CCTTGGCTTA TGCGTGTATG TCTGCTTTTA TTCCCAAATA TCTGTATAAC 1740

TTCTTCTTAA AAGACAACTC ACATGTAATA CAAGAGTATC TGACTGTCTT CTCTCAGATG 1800

ATTGCATTTC ATGATCCAGA GCTGAGTAAT CATCTCAATG AGATTGGCTT CATTCCAGAT 1860

GTAAGTACTT GGTGCGTTAC TAGAACATGC CTAATTTTTA AGATATACAA GATGTTGTTC 1920

AAACAGTGGA AAAGAAAAGA AATTAATAAC AAAAGTTACC TTCTTGGTGA TGGGGTTGCA 1980

GTT 1983

Domain Profile

S: 1     llaqdkdGsnGlplasnakkilGrfqiLkelqhdrLcqYldisrgkhervivvaehlels  60

         +l++d++GsnGlpl++n++kilGrfqiLk+++h+rLcqY+disrgkher++vvaeh+e+s

Q: 18    ALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERS  77

         589*********************************************************

S: 61    LeDllkerkpvseslvlriayevlsgldylnkhnivhralepksilldrkgqkvkLakyG  120

         LeDll+erkpvs+s+vl+ia+evl+gl+y+nkh+ivhral+p++illdrkg+ +kLak+G

Q: 78    LEDLLRERKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGH-IKLAKFG  136

         ****************************************************.*******

S: 121   LyhltayGkdvdfpigygsylaPerilqd.........edkllaatvksDvWsLglille  171

         Lyh+ta+G+dvdfpigy+sylaPe+i+q+         ++k+l++++ksDvWsLg+il+e

Q: 137   LYHMTAHGDDVDFPIGYPSYLAPEVIAQGifkttdhmsSKKPLPSGPKSDVWSLGIILFE  196

         ************************************************************

S: 172   lilgikLfaeldlserlkillklstvdetliklaeekkcldiikklderleallkkCLtl  231

         l++g+kLf++ld+serlk+ll+l++vd+tl +laee++cldiik+l+++ ++llkkCLt+

Q: 197   LCVGRKLFQSLDISERLKFLLTLDCVDDTLTVLAEEHGCLDIIKELPKTAIDLLKKCLTF  256

         ************************************************************

S: 232   lpskRpspdellkekvf  248

         +pskR +pdel+k+kvf

Q: 257   HPSKRLTPDELMKDKVF  273

         ***************98

Domain Sequence
(FASTA)

ALPHDVCGSN GLPLTPNSIK ILGRFQILKT ITHPRLCQYV DISRGKHERL VVVAEHCERS 60

LEDLLRERKP VSCSTVLCIA FEVLQGLQYM NKHGIVHRAL SPHNILLDRK GHIKLAKFGL 120

YHMTAHGDDV DFPIGYPSYL APEVIAQGIF KTTDHMSSKK PLPSGPKSDV WSLGIILFEL 180

CVGRKLFQSL DISERLKFLL TLDCVDDTLT VLAEEHGCLD IIKELPKTAI DLLKKCLTFH 240

PSKRLTPDEL MKDKVF 256

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0005097	; F:Rab GTPase activator activity
GO:0032851	; P:positive regulation of Rab GTPase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR000195	; Rab-GTPase-TBC_dom.
IPR001763	; Rhodanese-like_dom.

Pfam

PF00069	; Pkinase; 1.
PF00566	; RabGAP-TBC; 1.
PF00581	; Rhodanese; 1.

SMARTs

SM00450	; RHOD; 1.
SM00164	; TBC; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50206	; RHODANESE_3; 1.
PS50086	; TBC_RABGAP; 1.

Prints

Created Date

20-Feb-2013