EKS-CAJ-00248

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00248

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	358.6	3.3E-107	25	276	252

Status

Unreviewed

Ensembl Protein

ENSCJAP00000029246

UniProt Accession

F7HLQ7;

Protein Name

Protein Synonyms/Alias

Gene Name

SIK1

Gene Synonyms/Alias

SIK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000015879	ENSCJAP00000029246	ENSCJAT00000030904

Organism

Callithrix jacchus

Functional Description

Protein Length

785

Protein Sequence
(FASTA)

MVIMSEFSAD PAGQGQQKPL RVGFYDIERT LGKGNFAVVK LARHRVTKTQ VAIKIIDKTR 60

LDSSNLEKIY REVQLMKLLN HPHIIKLYQV METKDMLYIV TEFAKNGEMF DYLTSNGHLS 120

ESEARKKFWQ ILSAVEYCHD HHIVHRDLKT ENLLLDGNMD IKLADFGFGN FYKSGEPLST 180

WCGSPPYAAP EVFEGKEYEG PQLDIWSLGV VLYVLVCGSL PFDGPNLPTL RQRVLEGRFR 240

IPFFMSQDCE SLIRRMLVVD PARRISIAQI RQHRWMRAEP CLPEPCLGPA CPAFSAHSYS 300

SNLGDYDEQA LGIMQTLGVD RQRTVESLQN SSYNHFAAIY YLLLERLKEY RNAQCTRPGP 360

ARQPRPRSSD LSGLEVPREG FSADPFRPAL LCPQPQALVQ SVLQAEMDCE LQGSLQWPLF 420

FPVDAGCSGV FRPRPLSPSS LLDTAISEEA RQGPGLEEEQ DAQESLPGST GRRHTLAEVS 480

SRLSPLTAPC IVISPSATAS PAEGTSSDSC LTFSASRDPM ELSGTSATQG LLGAGSPVRL 540

ASPFLGSQSA TPVLQAQGGL GGAVLLPVSF QEGRRASDTS LTQGLKAFRQ QLRKTARTKG 600

FLGLNKIKGL ARQVCQAPAS RASRGGLSPF HAPAQSPGPH SGAASSREGR SLLEEVLEQQ 660

RLLQLQHHPA ATPSCSQAPQ PNPTPFVIAP CDGPGATLLP STLFTSGLPL LPPPLLQAGV 720

SPVTSAAQLL DTQLHIGASP TALPAAPLPR PARLAPGCEP LGLLQGDFEM EDLSPCPLGT 780

FVLVQ 785

Nucleotide Sequence
(FASTA)

ATGGTTATCA TGTCGGAGTT CAGCGCGGAC CCGGCGGGTC AGGGCCAGCA GAAGCCCCTC 60

CGGGTGGGTT TTTACGACAT CGAGCGGACC CTCGGCAAAG GCAACTTCGC GGTGGTGAAG 120

CTGGCGCGGC ATCGAGTCAC CAAAACGCAG GTTGCAATAA AAATAATTGA TAAAACACGA 180

TTAGATTCAA GCAACTTGGA GAAAATCTAT CGTGAGGTTC AGCTAATGAA GCTTCTGAAC 240

CACCCACACA TCATAAAGCT TTACCAGGTG ATGGAAACAA AGGACATGCT TTACATCGTT 300

ACCGAATTTG CTAAAAACGG AGAAATGTTT GATTATCTGA CTTCCAACGG GCACCTGAGT 360

GAGAGCGAGG CGCGGAAGAA GTTCTGGCAG ATCCTGTCCG CTGTGGAGTA CTGTCACGAC 420

CACCACATCG TCCACCGGGA CCTCAAGACC GAGAACCTGC TGCTGGATGG CAACATGGAC 480

ATCAAGCTGG CAGATTTTGG ATTTGGGAAT TTCTACAAGT CAGGAGAGCC TCTCTCCACG 540

TGGTGTGGGA GCCCCCCGTA TGCCGCCCCG GAAGTCTTTG AGGGAAAGGA ATATGAAGGC 600

CCCCAGTTGG ACATCTGGAG CCTGGGCGTG GTGCTGTACG TCCTGGTCTG CGGTTCTCTC 660

CCTTTCGACG GACCCAACCT GCCGACGCTG AGACAGCGGG TGCTGGAGGG CCGCTTCCGC 720

ATCCCCTTCT TCATGTCTCA AGACTGTGAG AGCCTGATCC GACGCATGCT GGTCGTGGAC 780

CCCGCCAGGC GCATCAGCAT CGCCCAGATC CGGCAGCACC GGTGGATGCG GGCCGAGCCC 840

TGCCTGCCGG AGCCCTGCCT GGGGCCTGCC TGCCCTGCCT TCTCTGCGCA CAGCTACAGC 900

TCCAACCTTG GTGACTACGA CGAGCAGGCT CTGGGCATCA TGCAGACCCT GGGCGTTGAC 960

CGGCAGAGGA CGGTGGAGTC ACTGCAAAAC AGCAGCTATA ACCACTTCGC TGCCATCTAT 1020

TACCTCCTCC TCGAGCGGCT CAAGGAGTAT CGGAATGCCC AGTGCACCCG CCCTGGGCCT 1080

GCCAGGCAGC CGCGGCCTCG GAGCTCGGAC CTCAGCGGCT TGGAGGTGCC TCGGGAAGGT 1140

TTTTCCGCTG ACCCTTTTCG ACCCGCCCTG CTGTGCCCGC AGCCGCAGGC CTTGGTGCAG 1200

TCCGTCCTGC AGGCCGAGAT GGACTGTGAG CTCCAGGGCT CGCTGCAGTG GCCCCTGTTC 1260

TTCCCGGTGG ATGCTGGCTG CAGCGGAGTG TTCCGGCCCC GGCCCCTGTC CCCCAGCAGC 1320

CTGCTGGACA CGGCCATCAG TGAGGAGGCC AGGCAGGGGC CGGGCCTCGA GGAAGAGCAG 1380

GATGCTCAGG AGTCCCTGCC TGGCAGCACG GGCCGGAGGC ACACCCTGGC CGAGGTCTCC 1440

AGCCGCCTAT CCCCACTCAC CGCTCCATGT ATAGTCATCT CCCCGTCCGC CACAGCGAGT 1500

CCTGCAGAGG GTACCAGCTC AGACAGTTGC CTGACCTTCT CCGCGAGCAG AGACCCTATG 1560

GAGCTCAGTG GCACCTCTGC CACTCAGGGG CTGCTGGGCG CCGGCTCCCC AGTCAGGCTG 1620

GCCTCGCCCT TTCTGGGGTC GCAGTCTGCC ACCCCCGTGC TGCAGGCCCA GGGGGGCTTG 1680

GGAGGAGCTG TCCTACTTCC TGTGAGCTTC CAGGAGGGAC GGAGGGCGTC GGACACCTCA 1740

CTGACTCAAG GGCTGAAGGC CTTTCGGCAG CAACTGAGGA AGACCGCGCG GACCAAAGGG 1800

TTTCTGGGGC TGAACAAAAT CAAGGGGCTC GCCCGCCAGG TGTGCCAGGC CCCCGCCAGC 1860

CGTGCCAGCA GGGGCGGCCT GAGCCCCTTC CACGCCCCTG CACAGAGTCC GGGCCCGCAC 1920

AGCGGTGCGG CCAGCAGCCG GGAGGGCCGG AGTCTGCTGG AGGAGGTGCT GGAGCAGCAG 1980

AGGCTGCTCC AGTTACAGCA CCACCCGGCC GCCACGCCCA GCTGCTCACA GGCCCCCCAG 2040

CCGAACCCCA CCCCATTTGT GATCGCCCCC TGTGATGGCC CTGGGGCCAC CCTGCTCCCC 2100

AGCACCCTCT TCACGTCAGG GCTCCCGCTG CTGCCACCCC CGCTCCTGCA GGCCGGCGTC 2160

TCCCCCGTGA CCTCGGCCGC GCAGCTCCTA GACACACAGC TGCATATTGG CGCCAGCCCC 2220

ACTGCCCTCC CTGCTGCGCC CCTGCCTCGC CCGGCCAGGC TGGCCCCAGG CTGTGAGCCC 2280

CTGGGGCTGC TGCAGGGGGA CTTCGAGATG GAGGACCTGA GCCCCTGCCC CCTGGGGACC 2340

TTTGTCCTGG TGCAG 2355

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y++ +tlG+g+f+ Vkla+h+ tk++va+Kii+k++l++++leki+rE++++k l+hp+i

Q: 25    YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHI  84

         899*********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         ikl++v+etk++ly+v+e+a++ge+fdy++++g+l+e+eark f q++sav+Y+h+++iv

Q: 85    IKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSESEARKKFWQILSAVEYCHDHHIV  144

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld +++ik+aDFG++n++k+g+ l+t+cGsppYaaPe+++gk+Yegp++D

Q: 145   HRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLD  204

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         +WslGvvLy+lv+g+lPfd++nl +l++++l+g+++ip+ +s+++esL+r++Lvvdp++R

Q: 205   IWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARR  264

         ************************************************************

S: 241   atieeilkhewl  252

         ++i +i++h+w+

Q: 265   ISIAQIRQHRWM  276

         ***********8

Domain Sequence
(FASTA)

YDIERTLGKG NFAVVKLARH RVTKTQVAIK IIDKTRLDSS NLEKIYREVQ LMKLLNHPHI 60

IKLYQVMETK DMLYIVTEFA KNGEMFDYLT SNGHLSESEA RKKFWQILSA VEYCHDHHIV 120

HRDLKTENLL LDGNMDIKLA DFGFGNFYKS GEPLSTWCGS PPYAAPEVFE GKEYEGPQLD 180

IWSLGVVLYV LVCGSLPFDG PNLPTLRQRV LEGRFRIPFF MSQDCESLIR RMLVVDPARR 240

ISIAQIRQHR WM 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013