EKS-CAJ-00467

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00467

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	428.8	1.9E-128	26	308	283

Status

Unreviewed

Ensembl Protein

ENSCJAP00000029374

UniProt Accession

F7I5F4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK13

Gene Synonyms/Alias

MAPK13;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000015899	ENSCJAP00000029374	ENSCJAT00000031039
ENSCJAG00000015899	ENSCJAP00000029368	ENSCJAT00000031033

Organism

Callithrix jacchus

Functional Description

Protein Length

365

Protein Sequence
(FASTA)

MSLIRKKGFY KQDVNKTVWE LPKTYVSPTH VGSGAYGAVC SAIDKRSGEK VAIKKLSRPF 60

QSEIFAKRAY RELQLLKHMQ HENVIGLLDV FTPASSLRNF HDFYLVMPFM QSDLQKIMGM 120

EFSEDKIQYL VYQMLKGLKY IHSAGVVHRD LKPGNLAVNE DCELKILDFG LARPADVEMT 180

GYVVTRWYRA PEVILSWMHY NQTVDIWSVG CIMAEMLTGK TLFKGKDYLD QLSQILKVTG 240

VPGTEFVQKL KDKAAKSYIQ ALPQSPKKDF TQLFPQASPQ AVDLLEKMLE LDVDKRLTAA 300

QALAHPFFEP FRDPEEETEA QHPFDDSLEH EKLTVDEWKQ HIYKEIVNFS PIARKDSRRR 360

SGMKL 365

Nucleotide Sequence
(FASTA)

ATGAGCCTCA TCAGGAAAAA AGGCTTCTAC AAGCAGGACG TCAACAAGAC CGTCTGGGAG 60

CTGCCCAAGA CCTACGTGTC CCCGACGCAC GTCGGCAGCG GGGCCTATGG CGCCGTGTGC 120

TCGGCCATCG ACAAGCGGTC AGGGGAGAAG GTGGCCATCA AGAAGCTGAG CCGGCCCTTC 180

CAGTCCGAGA TCTTCGCCAA GCGCGCCTAC CGGGAGCTGC AGCTGCTGAA GCACATGCAG 240

CATGAGAACG TAATTGGGCT CCTGGATGTC TTCACCCCAG CGTCCTCCCT GCGCAACTTC 300

CATGACTTCT ACCTGGTGAT GCCCTTCATG CAGTCGGATC TGCAGAAGAT CATGGGGATG 360

GAGTTCAGTG AGGATAAGAT CCAGTACCTG GTGTATCAGA TGCTCAAAGG CCTTAAGTAC 420

ATCCACTCAG CTGGGGTCGT GCACAGGGAC CTGAAGCCGG GCAACCTGGC TGTGAACGAG 480

GATTGTGAAC TGAAGATCCT GGATTTTGGG CTGGCACGGC CTGCAGATGT CGAGATGACT 540

GGCTACGTGG TGACCCGCTG GTACCGGGCC CCCGAGGTGA TCCTCAGCTG GATGCACTAC 600

AACCAGACAG TGGACATCTG GTCTGTCGGC TGTATCATGG CGGAGATGCT GACAGGGAAA 660

ACTCTGTTCA AGGGGAAAGA TTACCTGGAC CAGCTGAGCC AGATCCTGAA AGTGACCGGG 720

GTACCAGGCA CAGAGTTTGT GCAGAAGCTG AAAGACAAAG CGGCCAAATC CTACATCCAG 780

GCCCTGCCAC AGAGCCCCAA GAAGGATTTC ACTCAGCTCT TCCCACAGGC CAGCCCCCAG 840

GCCGTGGACC TGCTGGAGAA GATGCTGGAG CTGGACGTGG ACAAGCGCCT GACAGCCGCG 900

CAGGCCCTTG CCCATCCCTT CTTTGAACCC TTCCGGGACC CTGAGGAAGA AACGGAGGCC 960

CAGCATCCAT TTGATGATTC CTTAGAACAC GAGAAACTCA CAGTGGATGA ATGGAAGCAG 1020

CACATCTACA AGGAGATTGT GAACTTCAGC CCCATTGCCC GGAAGGACTC GCGGCGCCGG 1080

AGTGGCATGA AGCTGTAG 1098

Domain Profile

S: 2     eslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNii  61

          s +++g+Gayg v+sa+dkr++e+vaikklsrpfq+e+ akr++REl+llk+++heN+i

Q: 26    VSPTHVGSGAYGAVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELQLLKHMQHENVI  85

         566899******************************************************

S: 62    klldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHsa  121

          lldvftp+++l++++d+Ylv+ +m++dL+k++ ++ +s+++i++l+yq+l+glky+Hsa

Q: 86    GLLDVFTPASSLRNFHDFYLVMPFMQSDLQKIMGME-FSEDKIQYLVYQMLKGLKYIHSA  144

         **********************************99.9**********************

S: 122   nviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkey  181

         +v+HrDlKP+Nl+vnedcelkildFGlar ad e    +t+yv+trwYraPe++ls+++y

Q: 145   GVVHRDLKPGNLAVNEDCELKILDFGLARPADVE----MTGYVVTRWYRAPEVILSWMHY  200

         ********************************99....**********************

S: 182   tkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyik  241

         +++vDiWsvGCI+aE+ltgk+lf+gkd++dql++il+v+g p +ef++k++++ a++yi+

Q: 201   NQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLSQILKVTGVPGTEFVQKLKDKAAKSYIQ  260

         ************************************************************

S: 242   slpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

          lp+ +kkdf++lfp+as++a+dLlek+L+ld dkR+++++aL+hp++

Q: 261   ALPQSPKKDFTQLFPQASPQAVDLLEKMLELDVDKRLTAAQALAHPFF  308

         **********************************************95

Domain Sequence
(FASTA)

VSPTHVGSGA YGAVCSAIDK RSGEKVAIKK LSRPFQSEIF AKRAYRELQL LKHMQHENVI 60

GLLDVFTPAS SLRNFHDFYL VMPFMQSDLQ KIMGMEFSED KIQYLVYQML KGLKYIHSAG 120

VVHRDLKPGN LAVNEDCELK ILDFGLARPA DVEMTGYVVT RWYRAPEVIL SWMHYNQTVD 180

IWSVGCIMAE MLTGKTLFKG KDYLDQLSQI LKVTGVPGTE FVQKLKDKAA KSYIQALPQS 240

PKKDFTQLFP QASPQAVDLL EKMLELDVDK RLTAAQALAH PFF 283

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR008352	; MAPK_p38.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01773

; P38MAPKINASE.

Created Date

20-Feb-2013