EKS-CAJ-00352

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00352

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ack	384.3	5.6E-115	115	374	260

Status

Unreviewed

Ensembl Protein

ENSCJAP00000030248

UniProt Accession

F7AS73;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100395452

Gene Synonyms/Alias

LOC100395452;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000016438	ENSCJAP00000030248	ENSCJAT00000031964
ENSCJAG00000016438	ENSCJAP00000030254	ENSCJAT00000031970

Organism

Callithrix jacchus

Functional Description

Protein Length

659

Protein Sequence
(FASTA)

MLPEAGSLWL LKLLRDIQLA QFYWPILEEL NVTRPEHFDF VKPEDLDSIG MGRPAQRRLS 60

DLKRLRSGAS LDWVYNILGG LAPEHKEPTL PSQGPPHVPE PEGGLKCLIP EGAVCRRELL 120

GSGCFGVVHR GLWTLPSGKS VPVAVKSLRV GPEGPVGAEL GDFLREVSVM MNLEHPHVLR 180

LHGLILGQPL QMVMELAPLG SLHARLTAPA PTPPLPVALL FLFLRQLAGA MAYLGARGLV 240

HRDLATRNLL LASTSTIKVA DFGLVRPLSG ARGRYVMGGP RPIPYAWCAP ESLRHGAFSS 300

ASDVWMFGVT LWEMFSGGEE PWAGVPPYLI LQRLEDRARL PRPPLCSRTL YSLALRCWAP 360

HPADRPSFTH VEGLLQEAWP TEGCCVRDVT EPGALRMEPG DPITVIEGSP DSTIWKGQNG 420

RTFKVGSFPA SAVTLADAGG LPATRPVHRG TPARGDQHPG SIDGDRKKAN LWDVPPARGQ 480

RRNVPLERMK GISRSLESVL SLGPHPTGGG SSPPEIRQAR AVPQGPPGLR PRPPLSSSSP 540

QPSQPPRERL PWPKRKPPHN HLMGAPGASK AAVLSGGLLP DPELQRKIME VELSVHGVTH 600

QECQAALGAT RGDVVSAIQN LKVDQLFHLS SRSRADCRRI LEHYQWDLSA ASRYVLARP 659

Nucleotide Sequence
(FASTA)

ATGCTTCCTG AGGCTGGCTC CCTGTGGCTA CTAAAGCTGC TCCGGGACAT CCAGCTGGCC 60

CAGTTTTACT GGCCCATCCT TGAGGAGCTT AATGTCACTC GGCCAGAGCA CTTCGACTTT 120

GTCAAGCCTG AAGACCTGGA CAGCATTGGC ATGGGCCGGC CTGCCCAGCG CAGACTGTCG 180

GATCTAAAGA GGCTACGATC CGGTGCTAGT CTAGACTGGG TCTACAACAT CCTTGGAGGT 240

TTAGCCCCTG AGCACAAGGA GCCCACCCTG CCCTCGCAGG GCCCACCGCA CGTCCCTGAG 300

CCAGAGGGGG GACTCAAGTG TCTGATCCCA GAGGGTGCTG TGTGCAGAAG GGAGCTGCTG 360

GGCTCCGGCT GCTTTGGGGT GGTGCACCGA GGGCTGTGGA CGCTGCCCAG CGGCAAGAGT 420

GTCCCAGTGG CTGTCAAGTC CCTCCGGGTA GGTCCTGAAG GCCCGGTGGG TGCAGAGCTG 480

GGGGACTTCC TGCGAGAGGT ATCGGTCATG ATGAACTTGG AGCACCCGCA CGTGCTGCGT 540

CTGCACGGCC TGATACTGGG CCAGCCTCTG CAGATGGTGA TGGAGCTGGC GCCACTGGGC 600

TCCCTACACG CGCGCCTAAC AGCCCCGGCC CCGACACCCC CACTGCCTGT GGCCCTACTC 660

TTCCTCTTCC TGCGGCAGCT GGCGGGGGCC ATGGCCTACC TGGGGGCCCG GGGGCTGGTG 720

CACCGGGACC TCGCTACGCG CAACCTGCTG CTGGCGTCGA CGAGCACCAT CAAGGTGGCG 780

GACTTCGGGC TGGTGCGGCC TCTGAGCGGC GCCCGGGGCC GCTACGTCAT GGGCGGGCCC 840

CGCCCCATCC CCTACGCCTG GTGTGCCCCA GAGAGCCTGC GCCACGGAGC CTTCTCGTCT 900

GCCTCGGACG TGTGGATGTT TGGGGTGACG CTGTGGGAGA TGTTCTCAGG CGGCGAGGAA 960

CCCTGGGCCG GGGTCCCACC GTACCTCATC CTGCAGCGGC TGGAGGACAG AGCCCGGCTG 1020

CCTAGGCCCC CTCTCTGCTC CAGGACCCTC TACTCCCTTG CCTTGCGCTG CTGGGCCCCC 1080

CACCCTGCTG ACCGGCCTAG CTTTACCCAC GTGGAAGGCC TGCTGCAAGA GGCCTGGCCT 1140

ACAGAAGGAT GCTGTGTGAG GGATGTCACA GAGCCAGGTG CCCTGAGGAT GGAGCCTGGT 1200

GACCCCATCA CAGTCATCGA GGGCAGCCCT GACTCCACAA TCTGGAAGGG CCAGAATGGT 1260

CGCACCTTCA AAGTGGGCAG CTTCCCAGCC TCCGCAGTGA CTCTGGCAGA TGCAGGGGGC 1320

TTGCCAGCCA CCCGTCCAGT CCACAGAGGC ACCCCTGCCC GGGGAGATCA ACACCCAGGA 1380

AGCATAGATG GAGACAGAAA GAAGGCAAAT CTTTGGGATG TGCCTCCAGC ACGGGGCCAG 1440

AGAAGAAATG TGCCCCTTGA AAGGATGAAA GGCATTTCCA GGAGTCTGGA GTCAGTTCTG 1500

TCCCTGGGTC CTCACCCCAC AGGGGGTGGT TCAAGCCCCC CTGAAATTCG ACAAGCCAGA 1560

GCTGTACCCC AGGGACCCCC AGGCCTGCGT CCACGCCCAC CTTTATCCTC TAGCTCTCCT 1620

CAGCCCAGTC AGCCCCCTAG GGAGCGGCTT CCCTGGCCCA AAAGAAAACC CCCGCACAAT 1680

CACCTCATGG GAGCGCCTGG AGCTAGCAAA GCCGCTGTCC TCTCTGGAGG CCTCTTGCCC 1740

GATCCTGAGT TGCAGAGGAA GATTATGGAG GTGGAACTGA GTGTGCATGG AGTCACCCAC 1800

CAGGAGTGCC AGGCAGCACT GGGAGCCACC AGGGGAGATG TGGTTTCAGC CATCCAGAAC 1860

CTCAAGGTAG ACCAGCTCTT CCACCTGAGT AGCCGGTCCA GGGCTGACTG CCGGCGCATC 1920

CTAGAGCATT ACCAGTGGGA CCTCTCAGCT GCCAGTCGCT ATGTCCTGGC CAGGCCCTGA 1980

Domain Profile

S: 2     klleklGeGsfgvvkrgeWsapsgksvqvavkvlk..sdkllstelddflrevsvllkle  59

         ++ e+lG+G+fgvv+rg W+ psgksv+vavk+l+  ++  +++el+dflrevsv+++le

Q: 115   CRRELLGSGCFGVVHRGLWTLPSGKSVPVAVKSLRvgPEGPVGAELGDFLREVSVMMNLE  174

         67899*****************************9999**********************

S: 60    henlvrlyGvvltqplklvtelaelgslldrlrkeakrdsllvallleyavqiaeglayl  119

         h++++rl+G++l+qpl++v+ela+lgsl++rl+++a +++l+vall+ +++q+a ++ayl

Q: 175   HPHVLRLHGLILGQPLQMVMELAPLGSLHARLTAPAPTPPLPVALLFLFLRQLAGAMAYL  234

         ************************************************************

S: 120   eskrlvhrdlaarnlllaskklvkisdfGlvralgeeedlyvlaenkkvPfaWcaPeslr  179

         +++ lvhrdla+rnlllas++++k++dfGlvr+l+ ++++yv+  ++++P+aWcaPeslr

Q: 235   GARGLVHRDLATRNLLLASTSTIKVADFGLVRPLSGARGRYVMGGPRPIPYAWCAPESLR  294

         ************************************************************

S: 180   trkfssasdvWafGvtlWemfsyGeePWvglsglqilkkidkekerlekPeacpediysl  239

         + +fssasdvW+fGvtlWemfs GeePW+g++++ il++++ +++rl++P++c++ +ysl

Q: 295   HGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLE-DRARLPRPPLCSRTLYSL  353

         *****************************************.9*****************

S: 240   llkcWakkpadrpkfsalkek  260

         +l+cWa +padrp+f+++++

Q: 354   ALRCWAPHPADRPSFTHVEGL  374

         *****************9876

Domain Sequence
(FASTA)

CRRELLGSGC FGVVHRGLWT LPSGKSVPVA VKSLRVGPEG PVGAELGDFL REVSVMMNLE 60

HPHVLRLHGL ILGQPLQMVM ELAPLGSLHA RLTAPAPTPP LPVALLFLFL RQLAGAMAYL 120

GARGLVHRDL ATRNLLLAST STIKVADFGL VRPLSGARGR YVMGGPRPIP YAWCAPESLR 180

HGAFSSASDV WMFGVTLWEM FSGGEEPWAG VPPYLILQRL EDRARLPRPP LCSRTLYSLA 240

LRCWAPHPAD RPSFTHVEGL 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR001452	; SH3_domain.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013