EPS-CAJ-00007

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAJ-00007

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	151.5	3.1E-44	133	278	146

Status

Unreviewed

Ensembl Protein

ENSCJAP00000031553

UniProt Accession

F6TH82;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP27

Gene Synonyms/Alias

DUSP27;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000017165	ENSCJAP00000045329	ENSCJAT00000063802
ENSCJAG00000017165	ENSCJAP00000031557	ENSCJAT00000033360
ENSCJAG00000017165	ENSCJAP00000031553	ENSCJAT00000033355

Organism

Callithrix jacchus

Functional Description

Protein Length

1151

Protein Sequence
(FASTA)

MATSEDPEEE QVVPNEEDEA NVRAVQAHYL RSPSPSQYSM VSDAETESIF MDPIHLSSAI 60

AAKQIINEEL KPRGVRADAE CPGMLESAEQ LLVEDLYNRV REKMDDTSLY NTPCVLDLQR 120

ALVQDHQEAP WNEVDEVWPN VFIAEKSVAV NKGRLKRLGI THILNAAHGT GVYTGPEFYT 180

GLEIQYLGVE VDDFPEVDIS QHFRKAAEFL DEALLTYRGK VLISSEMGIS RSAVLVVAYL 240

MIFHNMAILE ALMTVRKKRA IYPNDGFLKQ LRELNEKLME EREEDYRLEG ESAEAEEGEG 300

SGSTLGARVH ALTVEEEDDS ASHLSGSSLG KASQASKPLT LIDEEEEEKL YKEWKKGQGL 360

PSGKVPQGGG GRRSASSGQS GEELQGEDEE EDVERIIQEW QSRNERYQAE GHSDAGSMVG 420

RRRRTLSESS AWESVSSHDI WVLKQQLELS RQNQGGRRRA DSVSSESTWD AWNERLLEIE 480

KEASRRYHAK SKREEAADLS SEAGSRVRED DEESVGSEAS SFYNFCSRNK DKLTALERWK 540

IKRIQFGFHK KDLEAGDSSS EPGAEEAAGE KKNPSDISLT AYQAWKLKHQ KKVGSENREE 600

VVELSKGEDL ALAKKRQRRL ELLERSRQTL EESQSMTSWE ADSSAASGSI PLSAFWSAAP 660

SVSADGDTAS VLSTQSHRSH LSQAASNIGG CSTSNPTTPL PNLPVGPGDT ISIASIQNWI 720

ANVVSETLAQ KQNEMLLLSR SPSVASMKAA PAASCLGDDQ VSMLSGQSSS SLGGCLLPQS 780

QARPSSDMQS VLSCNTTLSS PAEVSRSKVR GTSKPIYSLF ADNVDLKRLG QKEKEMQMEL 840

REKMSEYKME KLASDNKRSS LFKKKKVKED EDDGVGDRDE DADSAIGSFR YSSRSNSQKP 900

ETDTSSSLAV CDHYASGSRV GKEVDSSINK WLSGLRTEEK PPFQSDWSGS SRGKYTRSSL 960

LREMESKSSS YKFSKSRSEE QDSSSYNEAN GNSVRSTSRF SSSSTREGRE MHKFCRSTYS 1020

ETSSSREESP EPYFFRRTPE PSEREESPEP QHPSWARSRD WEDVEESSKS DFSEFGAKRK 1080

FTQSFMRSEE EGEKERTENR EEGRFASGRR FQYRRSTDRE EEEEMDDEAI IAAWRRRQEE 1140

TRTKLQRRRE D 1151

Nucleotide Sequence
(FASTA)

ATGGCGACGA GTGAGGACCC AGAGGAAGAG CAAGTAGTCC CAAATGAGGA GGATGAAGCC 60

AACGTGAGGG CAGTGCAGGC CCACTACCTC CGGAGCCCGT CCCCTAGCCA GTATTCCATG 120

GTCTCAGATG CAGAAACAGA AAGCATTTTC ATGGATCCCA TTCACCTCTC CTCAGCCATT 180

GCAGCCAAAC AGATCATCAA TGAAGAGCTC AAGCCACGGG GGGTCAGAGC AGACGCAGAG 240

TGTCCAGGCA TGCTGGAGTC TGCTGAACAG CTGCTGGTGG AGGACCTGTA CAACCGCGTC 300

AGGGAGAAGA TGGATGACAC CAGCCTCTAT AATACGCCCT GCGTCCTGGA CCTCCAGCGG 360

GCCCTAGTTC AGGATCACCA AGAGGCTCCC TGGAACGAGG TGGACGAGGT CTGGCCCAAC 420

GTCTTCATAG CTGAGAAGAG TGTGGCTGTG AACAAGGGGA GGCTGAAGAG GCTGGGAATC 480

ACCCACATTC TCAATGCTGC GCATGGCACC GGCGTTTACA CTGGCCCTGA ATTCTACACT 540

GGCCTGGAGA TCCAGTACTT GGGTGTGGAG GTAGATGACT TTCCTGAGGT GGACATTTCC 600

CAACATTTCC GGAAGGCGGC TGAGTTCCTC GATGAGGCGC TGCTGACCTA TAGAGGGAAA 660

GTCCTGATCA GCAGCGAAAT GGGCATCAGC CGGTCAGCGG TGCTGGTGGT CGCCTACCTG 720

ATGATCTTCC ACAACATGGC CATCCTGGAG GCTTTGATGA CCGTGCGCAA GAAGCGGGCC 780

ATCTACCCCA ACGACGGCTT CCTGAAGCAG CTGCGGGAGC TCAACGAGAA GCTGATGGAG 840

GAAAGAGAAG AGGACTATAG GCTGGAGGGG GAATCAGCTG AGGCTGAGGA GGGCGAGGGC 900

TCGGGGAGCA CGCTGGGGGC CAGAGTGCAC GCCCTGACGG TGGAGGAGGA GGACGACAGC 960

GCTAGCCACC TGAGTGGCTC CTCCCTGGGG AAGGCCAGCC AGGCCTCCAA GCCCCTCACC 1020

CTCATTGACG AGGAGGAGGA GGAGAAACTG TACAAGGAGT GGAAGAAAGG GCAGGGCCTC 1080

CCCTCGGGCA AGGTCCCCCA GGGTGGAGGT GGCAGACGCT CAGCCTCCTC TGGCCAGAGT 1140

GGGGAGGAGC TCCAGGGCGA GGACGAGGAG GAGGACGTGG AGAGGATCAT CCAGGAGTGG 1200

CAGAGCCGAA ACGAGAGGTA CCAAGCAGAA GGGCACAGCG ATGCTGGCTC CATGGTGGGG 1260

AGGCGGCGGC GCACCCTGAG CGAGAGCAGC GCCTGGGAGA GCGTGAGCAG CCACGACATC 1320

TGGGTCTTGA AGCAGCAGCT GGAGCTGAGC CGCCAGAACC AAGGCGGGAG GCGCCGCGCA 1380

GACTCGGTGT CCTCGGAGAG CACCTGGGAC GCGTGGAATG AGAGGCTGCT GGAGATTGAG 1440

AAGGAGGCTT CCCGGAGGTA CCATGCCAAG AGCAAGAGAG AGGAGGCGGC GGACCTGAGC 1500

TCAGAGGCGG GGAGCAGGGT GCGGGAGGAC GACGAGGAGA GCGTGGGCTC TGAGGCCAGC 1560

TCCTTCTACA ATTTCTGCAG CAGGAACAAG GACAAGCTCA CTGCTCTGGA GAGATGGAAG 1620

ATCAAGAGAA TCCAGTTTGG ATTTCACAAG AAAGACTTGG AAGCAGGAGA CAGCAGCAGT 1680

GAGCCCGGTG CAGAGGAGGC AGCGGGGGAG AAGAAGAACC CCTCCGACAT CAGCCTGACA 1740

GCCTACCAGG CCTGGAAGCT GAAACACCAG AAGAAGGTGG GCAGTGAGAA CAGGGAGGAG 1800

GTGGTGGAGC TCAGCAAGGG GGAGGACTTG GCCTTGGCTA AGAAGAGGCA ACGGAGGCTG 1860

GAGCTACTAG AGAGAAGCCG GCAGACGCTG GAGGAGAGCC AGTCTATGAC AAGCTGGGAG 1920

GCAGACAGCT CCGCGGCCAG CGGGAGTATT CCCCTGTCTG CGTTCTGGTC TGCAGCCCCC 1980

TCGGTCAGTG CTGATGGGGA CACGGCTTCG GTACTCAGCA CCCAGAGCCA CCGCTCCCAC 2040

CTGTCTCAGG CTGCCAGCAA TATAGGAGGG TGCTCAACCT CCAATCCCAC CACACCCCTG 2100

CCTAACCTGC CAGTGGGGCC TGGAGACACC ATTTCCATTG CCAGTATCCA GAACTGGATT 2160

GCCAATGTAG TCAGCGAGAC CCTTGCTCAG AAGCAAAATG AAATGCTGCT GCTGTCCCGA 2220

TCTCCGTCTG TTGCAAGCAT GAAGGCAGCA CCAGCGGCCA GCTGCCTGGG GGATGACCAA 2280

GTCTCTATGC TCAGCGGACA GAGCAGCTCC TCCTTGGGTG GCTGCCTGCT GCCTCAGAGC 2340

CAGGCAAGAC CCAGCTCTGA CATGCAGTCT GTGCTGTCCT GCAACACCAC ACTGAGCTCG 2400

CCGGCCGAAG TTTCCAGGAG CAAAGTGAGG GGGACCAGCA AGCCCATCTA CAGCCTCTTT 2460

GCTGACAATG TGGACCTAAA AAGACTTGGC CAGAAGGAGA AGGAGATGCA GATGGAGCTT 2520

AGGGAGAAGA TGTCCGAGTA CAAAATGGAA AAGCTGGCCT CAGACAATAA ACGCAGCTCC 2580

CTCTTCAAGA AGAAGAAGGT CAAGGAAGAT GAGGATGATG GTGTGGGTGA CAGGGATGAG 2640

GACGCTGACA GTGCTATAGG GAGCTTCCGA TATTCTTCCC GCAGTAATTC CCAGAAACCC 2700

GAAACAGACA CATCGTCCTC ACTGGCTGTC TGTGATCACT ATGCAAGTGG CAGCAGAGTT 2760

GGCAAAGAGG TGGATAGCAG TATTAATAAG TGGCTCAGTG GCCTCAGGAC AGAGGAAAAA 2820

CCTCCTTTCC AAAGTGACTG GTCTGGAAGT TCTAGGGGGA AGTATACCAG ATCATCTCTG 2880

CTCAGGGAGA TGGAGTCTAA ATCCTCCAGT TACAAGTTCT CCAAATCCCG GTCAGAGGAA 2940

CAGGACAGCT CCTCCTACAA CGAGGCAAAT GGCAACTCTG TAAGAAGCAC TTCGAGGTTC 3000

TCATCTTCCT CCACCAGGGA GGGCAGAGAG ATGCACAAGT TCTGCAGGTC CACGTACAGC 3060

GAGACCTCAA GTTCCCGAGA GGAGAGCCCA GAGCCCTACT TCTTCCGCAG GACCCCAGAG 3120

CCATCAGAAA GGGAAGAGTC CCCGGAGCCA CAGCACCCAA GCTGGGCCAG GTCCAGGGAC 3180

TGGGAAGATG TGGAAGAGTC ATCCAAGTCA GACTTCTCTG AATTTGGAGC CAAGAGGAAA 3240

TTCACCCAGA GCTTTATGAG GTCTGAAGAA GAGGGAGAGA AAGAGAGGAC GGAAAACAGA 3300

GAAGAAGGGA GGTTTGCATC TGGACGGCGC TTCCAGTATC GGAGAAGCAC TGACAGGGAG 3360

GAAGAGGAAG AAATGGATGA TGAAGCCATC ATTGCTGCTT GGAGACGCCG GCAAGAAGAA 3420

ACCAGGACCA AGCTGCAGAG GAGGAGGGAG GACTGA 3456

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         ev+e++p+++++++ +a+++  L++lgit+++na++++    ++Pe+++  +i+y++++v

Q: 133   EVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGV-YTGPEFYTGLEIQYLGVEV  191

         69**********************************8765.79*****************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD ++ d++q+f++aaef+dea  + +gkvl+ +++G+sRSa+lv+aYLm+++++++ +A

Q: 192   DDFPEVDISQHFRKAAEFLDEAlLTYRGKVLISSEMGISRSAVLVVAYLMIFHNMAILEA  251

         **********************8999**********************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         +++v++kr +i+pn+gfl+QL+el++kl

Q: 252   LMTVRKKR-AIYPNDGFLKQLRELNEKL  278

         ********.***************9987

Domain Sequence
(FASTA)

EVDEVWPNVF IAEKSVAVNK GRLKRLGITH ILNAAHGTGV YTGPEFYTGL EIQYLGVEVD 60

DFPEVDISQH FRKAAEFLDE ALLTYRGKVL ISSEMGISRS AVLVVAYLMI FHNMAILEAL 120

MTVRKKRAIY PNDGFLKQLR ELNEKL 146

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013