EKS-CAJ-00213

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00213

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	509.1	5.0E-153	4	287	284

Status

Unreviewed

Ensembl Protein

ENSCJAP00000037065

UniProt Accession

F6XY69;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000019926	ENSCJAP00000037065	ENSCJAT00000039144
ENSCJAG00000019926	ENSCJAP00000037062	ENSCJAT00000039141

Organism

Callithrix jacchus

Functional Description

Protein Length

487

Protein Sequence
(FASTA)

MEKYENLGLV GEGSYGMVMK CRNKDTGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 60

ENLVNLLEVY KKKKRWYLIF EFVDHTILDD LELFPNGLDY QVVQKYLFQI INGIGFCHSH 120

NIIHRDIKPE NILVSQSGIV KLCDFGFART LEAPGEAYTD YVATRWYRAP ELLVGDVKYG 180

KAVDVWAIGC LVTEMFMGEP LFPGDSDIDQ LYHIMMCLGN LILRHQELFY KNPVFAGVRL 240

PEIKERVPLE RRYPKLSEVV IDLAKKCLHI DPDKRPFCAE LLYHDFFQMD GFAERFSQEL 300

QLKVQKDARN ISLSKKSRNR KKEKEKDDSL GEERKTLLVQ DTNADSKIKD CKLFQIKGSK 360

TDGEKAEKGN RASKASCLHD NRKSHVKIVP STSLKDCSNV SVDHTRNPGV AIPPITHNLS 420

AVAPGINSSM GTATIPIQSY RMDDKTKKCS IPFVKLNRHS PSGIYNINVT TLVSGLPLSD 480

DSEADLP 487

Nucleotide Sequence
(FASTA)

ATGGAAAAAT ATGAGAACCT GGGATTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 60

TGCAGGAATA AAGATACTGG AAGAATTGTG GCCATCAAGA AGTTCTTAGA AAGTGACGAT 120

GACAAAATGG TTAAGAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ATTGAGGCAT 180

GAAAATTTGG TGAATCTCTT GGAAGTGTAT AAGAAGAAAA AACGATGGTA CCTAATTTTT 240

GAATTTGTTG ACCACACAAT TCTTGATGAC TTAGAGCTCT TTCCAAATGG ACTAGACTAC 300

CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 360

AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCATTGTC 420

AAGCTATGTG ATTTTGGATT TGCACGTACA TTGGAAGCTC CTGGGGAGGC TTATACTGAT 480

TATGTGGCAA CACGGTGGTA CAGAGCTCCA GAACTATTGG TTGGTGACGT CAAGTATGGC 540

AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 600

CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 660

CTAATTCTAA GACATCAGGA GCTTTTTTAT AAAAATCCTG TATTTGCTGG AGTAAGGTTG 720

CCTGAAATCA AGGAAAGAGT ACCTCTTGAA AGACGTTATC CTAAGCTCTC TGAAGTGGTG 780

ATAGATTTAG CAAAGAAATG CTTACATATT GACCCTGACA AAAGACCCTT CTGTGCTGAG 840

CTCTTATACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC TCAAGAACTA 900

CAATTAAAAG TACAGAAAGA TGCCAGAAAT ATTTCTTTAT CTAAAAAATC CCGAAACAGA 960

AAGAAGGAAA AAGAAAAAGA TGATTCTTTA GGTGAAGAAA GAAAAACACT TCTGGTACAG 1020

GATACCAATG CTGATTCCAA AATTAAGGAT TGTAAACTAT TTCAAATAAA AGGGTCAAAA 1080

ACTGATGGAG AAAAAGCTGA AAAAGGCAAC AGAGCTTCAA AAGCCAGCTG TCTCCATGAC 1140

AATAGGAAAA GCCATGTCAA AATAGTGCCT TCAACAAGCC TCAAAGATTG CAGCAATGTC 1200

AGTGTGGACC ACACAAGGAA TCCAGGTGTG GCAATTCCCC CAATTACGCA CAATCTTTCT 1260

GCAGTTGCTC CCGGTATTAA TTCTTCAATG GGGACTGCGA CTATACCAAT TCAGAGTTAC 1320

AGAATGGATG ACAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACTGAA CAGACATTCC 1380

CCATCAGGCA TTTATAATAT TAATGTGACC ACATTAGTAT CAGGACTTCC CCTGTCAGAT 1440

GATTCAGAGG CTGATTTGCC TTAA 1464

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcrnkdtg+ivaikkfles+ddk+vkkia+reikllkql+henl

Q: 4     YENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++yl+fe+vd+t+ld+le +pnG+++++v+k+l+qi+++i fch++nii

Q: 64    VNLLEVYKKKKRWYLIFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg+vklcdfGfar+l apg++ytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILVSQSGIVKLCDFGFARTLEAPGEAYTDYVATRWYRAPELLVGDVKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl++e+++Geplfpg+sd+dqly+i+++lG+li rhq++f+kn+vfaGv+lpe+

Q: 184   DVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLILRHQELFYKNPVFAGVRLPEI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++ +le++ypkl+ev++dl+kkcl++dp++r +c+ell h++f

Q: 244   KERVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLYHDFF  287

         ******************************************98

Domain Sequence
(FASTA)

YENLGLVGEG SYGMVMKCRN KDTGRIVAIK KFLESDDDKM VKKIAMREIK LLKQLRHENL 60

VNLLEVYKKK KRWYLIFEFV DHTILDDLEL FPNGLDYQVV QKYLFQIING IGFCHSHNII 120

HRDIKPENIL VSQSGIVKLC DFGFARTLEA PGEAYTDYVA TRWYRAPELL VGDVKYGKAV 180

DVWAIGCLVT EMFMGEPLFP GDSDIDQLYH IMMCLGNLIL RHQELFYKNP VFAGVRLPEI 240

KERVPLERRY PKLSEVVIDL AKKCLHIDPD KRPFCAELLY HDFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013