EKS-CAJ-00373

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00373

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Src	438.1	1.9E-131	242	491	250

Status

Unreviewed

Ensembl Protein

ENSCJAP00000038610

UniProt Accession

F7HZQ6;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100389637

Gene Synonyms/Alias

LOC100389637;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000020750	ENSCJAP00000038610	ENSCJAT00000040789

Organism

Callithrix jacchus

Functional Description

Protein Length

506

Protein Sequence
(FASTA)

RMGCVKSKFL RAGDNTFSKT EPSANPRCPV YVPDPTSTIK PGPNSNNSSP PGIGEAGSED 60

IVVVALYDYE AIHHEDLSFQ KGDQMVVLEE SGEWWKAQSL ATRKEGYIPS NYVARVDSLE 120

TEEWFFKGIS RKDAERQLLA PGNMLGSFMI RDSETTKGSY SLSVRDYDPR QGDTVKHYKI 180

RTLDNGGFYI SPRSTFTTLQ ELVVHYKKGS DGLCQKLSVP CVSSKPQKPW EKDAWEIPRE 240

SLKLEKKLGA GQFGEVWMAI YNKHTKVAVK TMKPGSMSVE AFLAEANVMK TLQHDKLVKL 300

HAVVTTEPIY IITEFMAKGS LLDFLKSDEG SKQPLPKLID FSAQIAEGMA FIEQRNYIHR 360

DLRAANILVS ASLVCKIADF GLARIIEDNE YTAREGAKFP IKWTAPEAIN FGSFTIKSDV 420

WSFGVLLMEI VTYGRIPYPG MSNPEVIRAL ERGYRMPRPE HCPEELYSIM TRCWKNRPEE 480

RPTFEYIQSV LDDFYTATES QYQQQP 506

Nucleotide Sequence
(FASTA)

AGGATGGGGT GCGTGAAGTC CAAGTTCCTC CGGGCCGGAG ACAATACATT CTCAAAAACT 60

GAACCCAGCG CCAATCCGCG CTGCCCTGTG TACGTGCCGG ATCCCACATC TACCATCAAG 120

CCGGGGCCTA ATAGCAACAA CAGCAGCCCA CCAGGAATCG GGGAGGCAGG CTCAGAGGAC 180

ATCGTCGTGG TTGCCCTGTA TGATTACGAG GCCATTCACC ACGAAGACCT CAGCTTCCAG 240

AAGGGGGACC AGATGGTGGT CCTGGAGGAA TCTGGGGAGT GGTGGAAGGC TCAATCCCTG 300

GCCACCCGGA AAGAGGGCTA CATCCCAAGC AACTATGTCG CCCGTGTTGA CTCTCTGGAG 360

ACAGAGGAGT GGTTCTTCAA GGGCATCAGC CGGAAGGACG CAGAGCGCCA GCTCCTGGCT 420

CCCGGCAACA TGCTTGGCTC CTTCATGATC CGGGATAGCG AGACCACGAA AGGAAGCTAC 480

TCTTTGTCCG TGCGAGACTA CGACCCTCGG CAGGGAGATA CCGTGAAACA TTACAAGATC 540

CGGACCCTGG ACAATGGGGG CTTCTACATA TCCCCCCGAA GCACCTTCAC CACCCTACAG 600

GAGCTGGTGG TCCACTACAA GAAGGGGAGC GATGGGCTCT GCCAGAAACT GTCGGTGCCC 660

TGCGTGTCTT CCAAGCCCCA GAAGCCTTGG GAGAAAGATG CCTGGGAGAT CCCCCGGGAA 720

TCCCTCAAGC TGGAGAAGAA ACTTGGAGCT GGGCAGTTTG GGGAAGTCTG GATGGCCATC 780

TACAACAAGC ACACCAAGGT GGCAGTGAAG ACGATGAAGC CAGGGAGCAT GTCGGTGGAG 840

GCCTTCCTGG CAGAGGCCAA TGTGATGAAA ACTCTGCAGC ATGACAAGCT GGTCAAACTT 900

CATGCGGTGG TCACCACGGA GCCCATCTAC ATCATCACGG AGTTCATGGC CAAAGGAAGC 960

CTGCTGGATT TTCTGAAAAG TGATGAGGGC AGCAAGCAGC CCTTGCCAAA ACTCATTGAC 1020

TTCTCAGCCC AGATTGCAGA AGGCATGGCC TTCATCGAGC AGAGGAACTA CATCCACCGA 1080

GACCTCCGAG CCGCCAACAT CTTGGTGTCT GCCTCCCTGG TGTGTAAGAT TGCCGACTTT 1140

GGCCTGGCCC GGATCATCGA GGACAATGAG TACACGGCTC GGGAAGGGGC CAAGTTCCCC 1200

ATCAAATGGA CAGCTCCTGA GGCCATCAAC TTTGGATCCT TCACCATCAA GTCAGACGTC 1260

TGGTCCTTTG GTGTCCTGCT GATGGAGATT GTCACCTATG GCCGGATCCC TTACCCAGGG 1320

ATGTCAAACC CTGAAGTGAT CCGAGCTCTG GAGCGTGGAT ACCGGATGCC CCGCCCAGAG 1380

CACTGCCCAG AGGAGCTCTA CAGCATCATG ACGCGCTGCT GGAAGAACCG TCCGGAGGAG 1440

CGGCCGACCT TTGAATACAT CCAGAGTGTG CTGGATGACT TCTACACGGC CACAGAGAGC 1500

CAGTACCAAC AGCAGCCATG A 1521

Domain Profile

S: 1     lklvkklGeGqfGevwlgkwkgsvkvavktlkegtlspeafleeaqilkklrheklvkly  60

         lkl+kklG+GqfGevw++ +++++kvavkt+k+g++s eafl+ea+++k+l+h+klvkl+

Q: 242   LKLEKKLGAGQFGEVWMAIYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLH  301

         689*********************************************************

S: 61    avvseeePiyivtelmakGslldflkeeegkklklpklvdlaaqvaeGmayleeknlihr  120

         avv++ ePiyi+te+makGslldflk++eg+k++lpkl+d++aq+aeGma++e++n+ihr

Q: 302   AVVTT-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR  360

         *****.******************************************************

S: 121   dlaarnvlvgeslvvkvadfGlarlieddeytakegaklPikWtaPeaiklgkftiksdv  180

         dl+a+n+lv+ slv+k+adfGlar+ied+eyta+egak+PikWtaPeai++g+ftiksdv

Q: 361   DLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDV  420

         ************************************************************

S: 181   WsfGillteivtkGkvPypGmtneevleqvergyrlprpeecpeelyelllecwkkdpee  240

         WsfG+ll+eivt+G++PypGm+n ev++++ergyr+prpe+cpeely+++++cwk++pee

Q: 421   WSFGVLLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPEHCPEELYSIMTRCWKNRPEE  480

         ************************************************************

S: 241   rPtfetlqevl  251

         rPtfe++q+vl

Q: 481   RPTFEYIQSVL  491

         *******9976

Domain Sequence
(FASTA)

LKLEKKLGAG QFGEVWMAIY NKHTKVAVKT MKPGSMSVEA FLAEANVMKT LQHDKLVKLH 60

AVVTTEPIYI ITEFMAKGSL LDFLKSDEGS KQPLPKLIDF SAQIAEGMAF IEQRNYIHRD 120

LRAANILVSA SLVCKIADFG LARIIEDNEY TAREGAKFPI KWTAPEAINF GSFTIKSDVW 180

SFGVLLMEIV TYGRIPYPGM SNPEVIRALE RGYRMPRPEH CPEELYSIMT RCWKNRPEER 240

PTFEYIQSVL 250

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR001452	; SH3_domain.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.
PF00018	; SH3_1; 1.

SMARTs

SM00252	; SH2; 1.
SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50001	; SH2; 1.
PS50002	; SH3; 1.

Prints

PR00401	; SH2DOMAIN.
PR00452	; SH3DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013