EKS-CAJ-00487

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00487

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	568.7	3.3E-171	13	271	259

Status

Unreviewed

Ensembl Protein

ENSCJAP00000039172

UniProt Accession

F7H024;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2A

Gene Synonyms/Alias

CAMK2A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000021031	ENSCJAP00000039167	ENSCJAT00000041376
ENSCJAG00000021031	ENSCJAP00000039172	ENSCJAT00000041381

Organism

Callithrix jacchus

Functional Description

Protein Length

489

Protein Sequence
(FASTA)

MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE 60

ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL 120

EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FAGFAGTPGY 180

LSPEVLRKDP YGKPVDLWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT 240

VTPEAKDINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK 300

GAILTTMLAT RNFSGGKSGG NKKSDGVKKR KSSSSVQLME SSESTNTTIE DEDTKVRKQE 360

IIKVTEQLIE AISNGDFESY TKMCDPGMTA FEPEALGNLV EGLDFHRFYF ENLWSRNSKP 420

VHTTILNPHI HLMGDESACI AYIRITQYLD AGGIPRTAQS EETRVWHRRD GKWQIVHFHR 480

SGAPSVLPH 489

Nucleotide Sequence
(FASTA)

ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 60

AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCTGGCCA AGAGTACGCT 120

GCCAAGATCA TCAACACCAA GAAGCTGTCA GCCAGAGACC ATCAGAAGCT GGAGCGTGAA 180

GCCCGCATCT GCCGCCTGCT GAAGCACCCC AACATCGTCC GACTCCATGA CAGCATCTCG 240

GAGGAGGGAC ACCACTACCT GATCTTCGAC CTGGTCACTG GTGGGGAATT GTTTGAAGAC 300

ATCGTGGCCC GGGAGTATTA CAGTGAGGCA GATGCCAGTC ACTGTATCCA GCAGATCCTG 360

GAGGCTGTGC TGCATTGCCA CCAGATGGGG GTGGTGCACC GGGACCTGAA GCCTGAGAAT 420

CTGTTGCTGG CCTCCAAGCT CAAGGGCGCT GCAGTGAAGC TGGCAGACTT TGGCCTGGCC 480

ATAGAGGTGG AGGGGGAACA GCAGGCATGG TTTGCAGGGT TTGCAGGGAC TCCTGGATAC 540

CTCTCCCCAG AAGTGCTGCG GAAGGACCCA TACGGGAAGC CTGTTGACTT GTGGGCTTGT 600

GGGGTCATCC TGTACATCCT GCTGGTTGGG TACCCCCCAT TCTGGGATGA GGACCAGCAC 660

CGCCTGTACC AGCAGATCAA AGCCGGCGCC TATGATTTCC CGTCACCGGA ATGGGACACC 720

GTCACCCCAG AAGCCAAGGA CATCAATAAG ATGCTAACCA TTAACCCATC TAAACGCATC 780

ACAGCTGCCG AAGCCCTTAA GCACCCCTGG ATCTCGCACC GCTCCACCGT GGCGTCCTGT 840

ATGCATAGAC AGGAGACCGT GGACTGCCTG AAGAAGTTCA ACGCCAGGAG GAAACTGAAG 900

GGAGCCATTC TCACCACAAT GCTGGCCACC AGGAACTTCT CTGGAGGGAA GAGTGGGGGA 960

AACAAGAAGA GCGATGGTGT GAAGAAAAGA AAGTCCAGTT CCAGCGTTCA GTTAATGGAA 1020

TCCTCAGAGA GCACCAACAC CACCATCGAG GATGAAGACA CCAAAGTGCG GAAACAGGAA 1080

ATTATAAAAG TGACAGAGCA GCTGATTGAA GCCATAAGCA ATGGAGATTT TGAGTCCTAC 1140

ACGAAGATGT GCGACCCTGG CATGACGGCC TTCGAACCTG AGGCCCTGGG GAACCTGGTT 1200

GAGGGCCTGG ACTTCCATCG ATTCTATTTT GAAAACCTGT GGTCCCGGAA CAGCAAGCCT 1260

GTGCACACTA CGATCCTGAA TCCCCACATC CACCTGATGG GCGATGAGTC GGCCTGCATT 1320

GCCTACATCC GCATCACGCA GTACCTGGAT GCCGGCGGCA TCCCCCGCAC CGCCCAATCG 1380

GAGGAGACCC GCGTCTGGCA CCGCCGGGAC GGCAAATGGC AGATTGTTCA CTTCCACAGA 1440

TCTGGGGCGC CCTCCGTCCT GCCCCACTGA 1470

Domain Profile

S: 1     yqlfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpni  60

         yqlfeelgkgafsvvrrcvkv +gqeyaakiintkklsardhqklerearicrllkhpni

Q: 13    YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI  72

         9***********************************************************

S: 61    vrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvv  120

         vrlhdsiseeg+hyl+fdlvtggelfedivareyyseadashciqqile+vlh+hq+gvv

Q: 73    VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV  132

         ************************************************************

S: 121   hrdlkpenlllaskakgaavkladfglaievqgdqqawf.gfagtpgylspevlrkdpyg  179

         hrdlkpenlllask+kgaavkladfglaiev+g+qqawf gfagtpgylspevlrkdpyg

Q: 133   HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFaGFAGTPGYLSPEVLRKDPYG  192

         **************************************989*******************

S: 180   kpvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkm  239

         kpvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakd inkm

Q: 193   KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD-INKM  251

         ******************************************************9.8***

S: 240   ltinpakritadealkhpwi  259

         ltinp+krita+ealkhpwi

Q: 252   LTINPSKRITAAEALKHPWI  271

         *******************8

Domain Sequence
(FASTA)

YQLFEELGKG AFSVVRRCVK VLAGQEYAAK IINTKKLSAR DHQKLEREAR ICRLLKHPNI 60

VRLHDSISEE GHHYLIFDLV TGGELFEDIV AREYYSEADA SHCIQQILEA VLHCHQMGVV 120

HRDLKPENLL LASKLKGAAV KLADFGLAIE VEGEQQAWFA GFAGTPGYLS PEVLRKDPYG 180

KPVDLWACGV ILYILLVGYP PFWDEDQHRL YQQIKAGAYD FPSPEWDTVT PEAKDINKML 240

TINPSKRITA AEALKHPWI 259

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013