EKS-CAJ-00332

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00332

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	324.5	1.0E-96	453	700	248

Status

Unreviewed

Ensembl Protein

ENSCJAP00000039736

UniProt Accession

F7IAR7;

Protein Name

Protein Synonyms/Alias

Gene Name

PAK7

Gene Synonyms/Alias

PAK7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000021343	ENSCJAP00000039733	ENSCJAT00000041976
ENSCJAG00000021343	ENSCJAP00000039736	ENSCJAT00000041979
ENSCJAG00000021343	ENSCJAP00000046708	ENSCJAT00000058476

Organism

Callithrix jacchus

Functional Description

Protein Length

719

Protein Sequence
(FASTA)

MFGKKKKKIE ISGPSNFEHR VHTGFDPQEQ KFTGLPQQWH SLLADTANRP KPMVDPSCIT 60

PIQLAPMKTI VRGNKPCKET SINGLLEDFD NISVTRSNSL RKESPPTPDQ GASSHGPGHV 120

EENGFITFSQ YSSESDTTAD YTTEKYREKS LYGDDLDPYY RGSHAAKQNG HVMKMKHGEA 180

YYSEMKPFKS DFARFSADYH SHLDSLSKPS EYSDLKWEYQ RASSSSHLDY SFQFTPSRTA 240

GTSGCSKESL AYSESEWGPS LDDYDRRPKS SYLNQTSPQP TMRQRSRSGS GLQEPMMPFG 300

ASAFKTHPQG HSYNSYTYPR LSEPTMCIPK VDYDRAQMVL SPPLSGSDTY PRGPAKLPQS 360

QSKAGYSSSS HQYPAGYHKA TLYHHPSLQS SSQYISTASY LSSLSLSSST YPPPSWGSSS 420

DQQPSRVSHE QFRAALQLVV SPGDPREYLD NFIKIGEGST GIVCIATEKH TGKQVAVKKM 480

DLRKQQRREL LFNEVVIMRD YHHDNVVDMY NSYLVGDELW VVMEFLEGGA LTDIVTHTRM 540

NEEQIATVCL SVLRALSYLH NQGVIHRDIK SDSILLTSDG RIKLSDFGFC AQVSKEVPKR 600

KSLVGTPYWM APEVISRLPY GTEVDIWSLG IMVIEMIDGE PPYFNEPPLQ AMRRIRDSLP 660

PRVKDLHKVS SVLRGFLDLM LVREPSQRAT AQELLGHPFL KLAGPPSCIV PLMRQYRHH 719

Nucleotide Sequence
(FASTA)

ATGTTTGGGA AGAAAAAGAA AAAGATTGAA ATATCTGGCC CATCCAACTT TGAACACAGG 60

GTTCATACTG GGTTTGATCC ACAAGAGCAG AAGTTTACCG GCCTTCCACA GCAATGGCAC 120

AGCCTGTTAG CAGATACGGC CAACAGGCCA AAGCCTATGG TGGACCCTTC ATGTATTACA 180

CCCATACAGC TGGCTCCTAT GAAGACAATC GTTAGAGGAA ACAAACCGTG CAAGGAAACC 240

TCCATCAATG GCCTGCTAGA GGATTTCGAC AACATCTCGG TGACTCGCTC CAACTCCCTA 300

AGGAAAGAAA GCCCACCCAC CCCAGATCAG GGAGCCTCCA GCCACGGTCC AGGCCACGTG 360

GAAGAAAACG GCTTCATCAC CTTCTCCCAG TATTCCAGCG AATCCGATAC TACTGCTGAC 420

TACACAACTG AAAAGTACAG AGAGAAGAGT CTCTATGGAG ACGACCTGGA TCCGTATTAC 480

AGAGGCAGCC ATGCAGCCAA GCAAAATGGG CATGTAATGA AAATGAAGCA CGGGGAGGCC 540

TACTATTCTG AGATGAAGCC TTTTAAATCA GATTTTGCCA GATTTTCTGC AGATTATCAC 600

TCACATTTGG ACTCACTGAG CAAACCAAGT GAGTATAGTG ACCTCAAGTG GGAGTATCAG 660

AGAGCCTCGA GTAGCTCCCA TCTGGATTAT TCATTCCAAT TCACACCTTC TAGAACTGCA 720

GGGACCAGTG GGTGCTCCAA GGAGAGCCTG GCCTACAGTG AAAGTGAATG GGGACCCAGC 780

CTGGATGACT ATGACAGGAG GCCAAAGTCA TCGTACCTAA ATCAGACGAG CCCTCAGCCC 840

ACCATGCGGC AGAGGTCCAG GTCAGGCTCG GGGCTCCAGG AACCGATGAT GCCATTTGGA 900

GCAAGTGCAT TTAAAACCCA TCCCCAAGGA CACTCCTACA ACTCCTACAC CTACCCTCGC 960

TTGTCCGAGC CCACAATGTG CATTCCAAAG GTGGATTACG ATCGAGCACA GATGGTCCTC 1020

AGCCCTCCAC TGTCAGGGTC TGACACCTAC CCCAGGGGCC CTGCCAAACT ACCTCAAAGT 1080

CAAAGCAAAG CAGGCTATTC CTCAAGCAGC CACCAGTATC CGGCTGGGTA CCACAAAGCC 1140

ACCTTGTACC ACCACCCTTC CCTGCAGAGC AGTTCGCAGT ACATCTCCAC GGCTTCCTAC 1200

CTGAGCTCCC TCAGCCTCTC ATCCAGCACC TACCCGCCGC CCAGCTGGGG CTCCTCCTCT 1260

GACCAGCAGC CCTCCAGGGT GTCCCATGAA CAGTTTCGGG CAGCCCTGCA GCTGGTGGTC 1320

AGCCCAGGAG ACCCCAGGGA ATACTTGGAC AACTTTATCA AAATCGGGGA AGGCTCAACC 1380

GGCATCGTGT GCATCGCCAC CGAGAAACAC ACAGGGAAAC AAGTTGCAGT GAAGAAAATG 1440

GACCTCCGGA AGCAACAGAG ACGGGAACTG CTTTTTAATG AGGTCGTGAT CATGCGGGAT 1500

TACCACCATG ACAATGTGGT TGACATGTAC AACAGCTACC TTGTTGGTGA TGAGCTCTGG 1560

GTGGTCATGG AGTTTCTAGA AGGTGGTGCC TTGACAGACA TCGTGACTCA CACCAGAATG 1620

AATGAAGAAC AGATAGCTAC TGTCTGCCTG TCAGTTCTGA GAGCTCTCTC CTACCTTCAT 1680

AACCAAGGAG TGATTCACAG GGACATAAAA AGTGACTCCA TCCTCCTGAC AAGTGATGGC 1740

CGGATAAAGT TATCTGATTT TGGTTTCTGT GCTCAAGTTT CCAAAGAAGT GCCAAAGAGG 1800

AAATCATTGG TTGGCACTCC CTACTGGATG GCTCCTGAGG TGATTTCTAG GCTACCTTAT 1860

GGGACAGAGG TGGACATCTG GTCCCTCGGG ATCATGGTGA TTGAAATGAT CGATGGCGAG 1920

CCCCCTTACT TCAATGAGCC CCCTCTCCAG GCGATGCGGA GGATCAGGGA CAGTTTACCT 1980

CCAAGAGTGA AGGACCTACA CAAGGTTTCT TCAGTGCTCC GGGGATTTCT AGACCTGATG 2040

TTGGTGAGGG AGCCCTCTCA GAGAGCAACA GCACAGGAAC TCCTTGGACA TCCATTTTTA 2100

AAACTAGCAG GTCCACCATC TTGCATCGTC CCCCTCATGA GACAATACAG ACATCACTGA 2160

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyles  64

          +ig+G++g v++a+ek+tg++va+kk++l+kq++ e+l++e+ ++++++h n+v++++s

Q: 453   IKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNS  512

         68**********************************************************

S: 65    flkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHrdi  124

         +l+ +elw+vme+l+gG+l+d+v+   +++++Eeqia+++ +vl+aL+ylH+++viHrdi

Q: 513   YLVGDELWVVMEFLEGGALTDIVT---HTRMNEEQIATVCLSVLRALSYLHNQGVIHRDI  569

         ************************...9********************************

S: 125   kakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaDiw  184

         k+++iLlt++g++kLsdfg++aq++k++ krk++vgtpywmAPEvi+  +  Y +++Diw

Q: 570   KSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVIS--RLPYGTEVDIW  627

         ***********************************************..9**********

S: 185   slGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqknpek  244

         slGI++ie+++gepP+++++pl+a+ +i ++ pp++k+ +k+s+ ++ f++ +l ++p++

Q: 628   SLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLVREPSQ  687

         ************************************************************

S: 245   RpsasellkhkFl  257

         R++a+ell h+Fl

Q: 688   RATAQELLGHPFL  700

         ************7

Domain Sequence
(FASTA)

IKIGEGSTGI VCIATEKHTG KQVAVKKMDL RKQQRRELLF NEVVIMRDYH HDNVVDMYNS 60

YLVGDELWVV MEFLEGGALT DIVTHTRMNE EQIATVCLSV LRALSYLHNQ GVIHRDIKSD 120

SILLTSDGRI KLSDFGFCAQ VSKEVPKRKS LVGTPYWMAP EVISRLPYGT EVDIWSLGIM 180

VIEMIDGEPP YFNEPPLQAM RRIRDSLPPR VKDLHKVSSV LRGFLDLMLV REPSQRATAQ 240

ELLGHPFL 248

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013