EKS-CAJ-00238

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00238

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	426.6	7.4E-128	44	304	261

Status

Unreviewed

Ensembl Protein

ENSCJAP00000009846

UniProt Accession

F7F6V7;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000036648	ENSCJAP00000009846	ENSCJAT00000010403

Organism

Callithrix jacchus

Functional Description

Protein Length

382

Protein Sequence
(FASTA)

MDGETAEEQE GPVPPPVAPS GPGLGGAPGG RREPKKYAVT DDYKLSKQVL GLGVNGKVLE 60

CFHRCTGQKC ALKLLYDSPK ARQEVDHHWQ ASGGPHIVRI LDVYENMHHG KRCLLIIMEC 120

MEGGELFSRI QERGDQAFTE REAAEIMRDI GTAIQFLHSH NIAHRDVKPE NLLYTSKEKD 180

AVLKLTDFGF AKETTQNALQ TPCYTPYYVA PEVLGPEKYD KSCDMWSLGV IMYILLCGFP 240

PFYSNTGQAI SPGMKRRIRL GQYGFPNPEW SEVSEDAKQL IRLLLKTDPT ERLTITQFMN 300

HPWINQSMVV PQTPLHTARV LQEDKDHWDE VKEEMTSALA TMRVDYDQVK IKDLKTSNNR 360

LLNKRRKKQA GSSSATQGCN NQ 382

Nucleotide Sequence
(FASTA)

ATGGATGGTG AAACAGCAGA GGAGCAGGAG GGCCCTGTGC CCCCACCAGT TGCACCCAGC 60

GGACCCGGCT TGGGCGGTGC TCCCGGGGGG CGGCGGGAGC CCAAGAAGTA CGCAGTGACC 120

GACGACTACA AGTTGTCCAA GCAGGTGCTG GGCCTTGGTG TGAACGGCAA GGTGCTGGAG 180

TGCTTCCATC GGTGCACTGG GCAGAAGTGT GCTCTGAAGC TCCTGTATGA TAGCCCCAAG 240

GCCCGGCAGG AGGTGGACCA TCACTGGCAG GCCTCTGGTG GCCCCCACAT TGTCCGCATC 300

CTGGATGTGT ATGAGAACAT GCACCATGGC AAGCGCTGTC TCCTCATCAT CATGGAATGC 360

ATGGAAGGTG GTGAGTTGTT CAGCAGGATT CAGGAGCGTG GCGACCAGGC TTTCACTGAG 420

AGAGAAGCTG CAGAGATAAT GCGGGATATC GGCACTGCCA TCCAGTTTCT GCACAGCCAT 480

AACATCGCCC ACCGAGATGT CAAGCCTGAA AACCTGCTCT ACACATCTAA GGAGAAAGAC 540

GCAGTACTTA AGCTCACCGA TTTTGGCTTT GCTAAGGAGA CCACCCAAAA TGCCCTGCAG 600

ACACCCTGCT ATACTCCCTA TTATGTGGCC CCTGAGGTCC TGGGTCCAGA GAAGTATGAC 660

AAGTCATGCG ACATGTGGTC CCTGGGTGTC ATTATGTATA TCCTCCTTTG TGGCTTCCCA 720

CCCTTCTACT CCAACACGGG CCAGGCCATC TCCCCAGGGA TGAAGAGGAG GATCCGCCTG 780

GGCCAGTATG GTTTCCCCAA TCCTGAGTGG TCAGAGGTCT CTGAGGATGC CAAGCAGCTG 840

ATCCGCCTCC TCCTGAAGAC AGACCCCACA GAGAGGCTGA CCATCACTCA GTTCATGAAC 900

CATCCCTGGA TCAACCAATC GATGGTGGTG CCGCAGACCC CACTCCACAC GGCCCGAGTG 960

CTGCAGGAGG ACAAAGATCA TTGGGATGAA GTCAAGGAGG AGATGACCAG TGCTTTGGCC 1020

ACTATGCGGG TAGACTACGA CCAGGTGAAG ATCAAGGACC TGAAGACCTC TAACAACCGG 1080

CTCCTCAACA AGAGGAGGAA AAAGCAGGCA GGCAGCTCCT CTGCCACACA AGGCTGCAAC 1140

AACCAGTAG 1149

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         kl+++vlG G++gkvlec+++ tg+k+alk+l+d++k+r+ev++h+qasg ++iv+++dv

Q: 44    KLSKQVLGLGVNGKVLECFHRCTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDV  103

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++++ll+++e++eGGel+sriqer  +afte+ea+e+++di++a++flhs+nia

Q: 104   YENMHHGKRCLLIIMECMEGGELFSRIQERgdQAFTEREAAEIMRDIGTAIQFLHSHNIA  163

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+skek+a++kl+Dfg+ake +++++l+tpc+t++yvaPevl++ek

Q: 164   HRDVKPENLLYTSKEKDAVLKLTDFGFAKE-TTQNALQTPCYTPYYVAPEVLGPEK----  218

         *****************************7.7899*********************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri+ g+y fP++eWsevse+a

Q: 219   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDA  277

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+lir lLk+dp+erlti++++nhpw+

Q: 278   KQLIRLLLKTDPTERLTITQFMNHPWI  304

         **************************8

Domain Sequence
(FASTA)

KLSKQVLGLG VNGKVLECFH RCTGQKCALK LLYDSPKARQ EVDHHWQASG GPHIVRILDV 60

YENMHHGKRC LLIIMECMEG GELFSRIQER GDQAFTEREA AEIMRDIGTA IQFLHSHNIA 120

HRDVKPENLL YTSKEKDAVL KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRLGQY GFPNPEWSEV SEDAKQLIRL 240

LLKTDPTERL TITQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013