EKS-CAP-00255

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00255

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	381.8	1.7E-114	65	326	262

Status

Unreviewed

Ensembl Protein

ENSCPOP00000000123

UniProt Accession

H0UT94;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K3

Gene Synonyms/Alias

MAP2K3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000000140	ENSCPOP00000000123	ENSCPOT00000000141

Organism

Cavia porcellus

Functional Description

Protein Length

348

Protein Sequence
(FASTA)

RRCPALGPPC PDAPASLGKP KRKRDLRITC VYKTPALNPT PPRNLDSRTF ITIGDRNFEV 60

EADDLVTISE LGRGAYGVVE KVRHAQSGTI MAVKRIRATV NSQEQKRLLM DLDVNMRTVD 120

CFYTVTFYGA LFREGDVWIC MELMDTSLDK FYRKVLEKNM TIPEDILGEI AVSIVRALEH 180

LHSKLSVIHR DVKPSNVLIN REGHVKMCDF GISGYLVDSV AKTMDAGCKP YMAPERINPE 240

LNQKGYNVKS DVWSLGITMI EMAILRFPYE SWGTPFQQLK QVVEEPSPQL PADRFSPEFV 300

DFTAQCLRKN PAERMNYLEL MEHPFFTLHK TKKTDIAAFV KEILGEDS 348

Nucleotide Sequence
(FASTA)

CGTAGGTGTC CAGCCCTTGG CCCTCCTTGC CCTGATGCCC CAGCCAGTTT AGGAAAACCC 60

AAGAGGAAGA GGGATTTACG GATAACCTGT GTGTACAAGA CCCCTGCGCT CAACCCCACA 120

CCGCCCCGGA ACCTGGACTC CCGGACTTTC ATCACCATTG GAGACCGAAA CTTCGAGGTG 180

GAGGCTGATG ACCTAGTGAC CATCTCAGAG CTGGGCCGTG GAGCTTATGG GGTAGTAGAG 240

AAGGTTCGAC ATGCCCAGAG TGGCACAATC ATGGCTGTGA AGCGGATCCG GGCCACTGTG 300

AACTCCCAGG AACAGAAGCG TCTACTCATG GACCTGGACG TCAACATGCG CACAGTCGAC 360

TGCTTCTACA CTGTCACCTT CTACGGGGCC CTCTTTAGAG AGGGGGATGT ATGGATCTGC 420

ATGGAGCTCA TGGACACATC CCTAGACAAG TTCTACCGGA AGGTGCTGGA GAAAAACATG 480

ACAATTCCAG AGGACATTCT GGGGGAAATC GCTGTGTCTA TCGTGCGTGC CCTGGAGCAC 540

CTGCACAGCA AGCTGTCTGT GATCCACAGA GATGTGAAGC CATCCAACGT GCTGATCAAC 600

AGGGAGGGCC ACGTGAAGAT GTGCGACTTT GGCATCAGCG GCTACCTGGT GGACTCTGTG 660

GCTAAGACGA TGGATGCTGG CTGCAAGCCC TACATGGCTC CAGAAAGAAT CAACCCAGAG 720

CTGAACCAGA AGGGCTACAA CGTCAAGTCT GATGTCTGGA GTCTCGGCAT CACCATGATT 780

GAGATGGCTA TTCTACGGTT TCCTTACGAG TCCTGGGGGA CCCCGTTCCA GCAGCTGAAG 840

CAGGTGGTGG AGGAACCATC CCCTCAGCTC CCAGCAGACC GTTTCTCCCC CGAGTTTGTG 900

GACTTCACTG CCCAGTGCCT AAGAAAGAAC CCTGCAGAGC GCATGAATTA CCTGGAGCTG 960

ATGGAGCACC CTTTCTTTAC TTTGCACAAA ACCAAGAAGA CGGACATTGC TGCCTTTGTG 1020

AAGGAGATCC TGGGAGAGGA CTCATAG 1047

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         l +++elG+G++gvVekv+h +sg+i+avK+ir++++++eqk++l++l+v +++ ++ y+

Q: 65    LVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDCFYT  124

         56899*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icmelmd tsldk+++kvlek+ +ipe++lg+iav++v+ale+l++

Q: 125   VTFYGALFREGDVWICMELMD-TSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHLHS  183

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         kl++iHRDvKPsN+L+n++G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +

Q: 184   KLSVIHRDVKPSNVLINREGHVKMCDFGISGYLVDSVAKTMdAGCKPYMAPERINPelnQ  243

         ********************************************************9999

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         k Y+vksdvWslG+t++e+a+ r+pye++ +++++lk++v+e++p+lp+++fs+ef++f

Q: 244   KGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFT  303

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         ++Cl+k+++eR+++ el++h+f+

Q: 304   AQCLRKNPAERMNYLELMEHPFF  326

         *********************96

Domain Sequence
(FASTA)

LVTISELGRG AYGVVEKVRH AQSGTIMAVK RIRATVNSQE QKRLLMDLDV NMRTVDCFYT 60

VTFYGALFRE GDVWICMELM DTSLDKFYRK VLEKNMTIPE DILGEIAVSI VRALEHLHSK 120

LSVIHRDVKP SNVLINREGH VKMCDFGISG YLVDSVAKTM DAGCKPYMAP ERINPELNQK 180

GYNVKSDVWS LGITMIEMAI LRFPYESWGT PFQQLKQVVE EPSPQLPADR FSPEFVDFTA 240

QCLRKNPAER MNYLELMEHP FF 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013