EPS-CAP-00020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAP-00020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	270.2	2.1E-80	68	369	302

Status

Unreviewed

Ensembl Protein

ENSCPOP00000000300

UniProt Accession

H0UTQ0;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000000343	ENSCPOP00000000300	ENSCPOT00000000346

Organism

Cavia porcellus

Functional Description

Protein Length

601

Protein Sequence
(FASTA)

MAGLYSLGVS VFSDQGGRKY MEDVTQIVVE PEPTAEEKPS PRRSLSQPSP SQPSPSAFPG 60

GEVSGTGRAR DARDPAPDAG ASPGGRCCRR RSSVAFFAVC DGHGGREAAQ FAREHLWGFI 120

KKQKGFTSSE PAKVCAAIRK GFLACHLAMW KKLAEWPKTM TGLPSTSGTT ASVVIIRGMK 180

MYVAHVGDSG VVLGIQDDPK NDFVRAVEVT QDHKPELPKE RERIEGLGGS VMNKSGVNRV 240

VWKRPRLTHS GPVRRSTVID QIPFLAVARA LGDLWSYDFF SGEFVVSPEP DTSVHTLDPQ 300

KHKYIILGSD GLWNMIPPQD AVSMCQDQEE KKYLTGEHGQ SCAKMLVNRA LGRWRQRMLR 360

ADNTSAIVIS ISPGVDNQGD FTNEDELFLN LTDSPSYNSQ DTCVINPSPC STPPVKSLEE 420

DPWPRLNSKD HIPTLVRSNA FSENLLEIPT EITRGSVQAI IIPSKDPEPL EENCTKTLTL 480

RIHDSLNNTL SVGLVPTNST NTMLDQKNLK VSTPGQMKAQ EVERTPPANF KRTLEESNSG 540

PLMKKHRRNG LSRSSGAQPA SLPATSQRKN SVKLTMRRRL RGQKKIGNPL LHQHRKTVCV 600

C 601

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGTACTCGCT CGGAGTGAGC GTCTTCTCAG ACCAGGGCGG GAGGAAGTAC 60

ATGGAGGACG TTACTCAGAT CGTGGTGGAG CCCGAGCCGA CAGCTGAAGA AAAGCCGTCG 120

CCCCGGCGAT CGCTGTCGCA GCCGTCGCCT TCACAACCGT CGCCGTCCGC CTTTCCTGGC 180

GGCGAAGTCT CGGGGACAGG CCGAGCCCGG GATGCCCGCG ATCCTGCGCC GGACGCCGGG 240

GCCTCGCCGG GCGGCCGCTG CTGCCGCCGC CGCTCCTCCG TAGCTTTCTT TGCCGTGTGT 300

GACGGACACG GCGGGCGGGA GGCGGCACAG TTCGCCCGCG AGCACTTATG GGGTTTTATC 360

AAGAAGCAGA AGGGTTTCAC CTCGTCCGAG CCGGCGAAGG TCTGTGCCGC TATCCGCAAG 420

GGCTTCCTCG CTTGTCACCT CGCCATGTGG AAGAAACTGG CAGAATGGCC AAAGACAATG 480

ACAGGTCTGC CCAGCACATC AGGGACAACT GCCAGTGTGG TCATCATACG GGGCATGAAG 540

ATGTATGTAG CTCATGTAGG TGATTCAGGG GTGGTCCTTG GAATTCAGGA TGACCCGAAG 600

AATGATTTTG TCAGAGCTGT GGAGGTGACA CAGGACCATA AGCCAGAACT TCCCAAGGAA 660

AGAGAACGAA TTGAAGGACT TGGTGGGAGT GTGATGAACA AGTCCGGAGT GAACCGTGTA 720

GTTTGGAAAA GGCCTCGGCT CACTCATAGT GGACCTGTTA GAAGGAGCAC AGTTATTGAC 780

CAGATTCCTT TCCTGGCAGT AGCCAGAGCA CTTGGTGATC TGTGGAGCTA TGATTTCTTC 840

AGTGGTGAGT TTGTGGTATC ACCAGAGCCA GACACGAGTG TCCACACACT CGATCCTCAG 900

AAGCACAAGT ATATTATCTT GGGGAGTGAC GGGCTTTGGA ACATGATTCC ACCTCAAGAT 960

GCTGTTTCAA TGTGCCAGGA TCAAGAGGAA AAAAAATACT TGACGGGTGA ACATGGCCAG 1020

TCCTGTGCCA AAATGCTTGT GAATAGAGCA CTAGGCCGCT GGAGGCAGCG TATGCTTCGA 1080

GCAGATAACA CCAGTGCTAT AGTAATCTCC ATCTCGCCAG GAGTGGACAA TCAGGGAGAC 1140

TTCACCAATG AAGATGAGCT CTTCCTGAAT CTGACCGATA GCCCTTCCTA CAATAGTCAA 1200

GACACCTGTG TAATCAATCC TTCCCCATGT TCTACACCTC CAGTCAAGTC CCTGGAAGAG 1260

GATCCATGGC CCAGGCTGAA CTCTAAAGAC CATATACCTA CCCTCGTTCG CAGTAATGCC 1320

TTCTCAGAGA ATCTTTTAGA GATCCCAACT GAGATAACTC GAGGGAGTGT CCAGGCTATA 1380

ATCATACCCT CAAAAGACCC AGAGCCACTT GAGGAAAATT GCACTAAAAC CCTAACTTTA 1440

AGGATACATG ATTCTTTGAA CAATACTCTG TCAGTTGGCC TTGTGCCTAC AAATTCAACA 1500

AATACCATGT TGGACCAAAA AAATTTAAAG GTATCCACTC CTGGTCAAAT GAAGGCCCAA 1560

GAAGTTGAAA GAACTCCTCC AGCAAACTTT AAAAGGACTT TGGAAGAATC CAACTCTGGC 1620

CCACTTATGA AAAAGCACAG ACGCAATGGC TTAAGTCGAA GTAGCGGTGC TCAGCCTGCA 1680

AGCCTCCCTG CCACCTCACA GCGGAAGAAC TCTGTTAAAC TCACCATGCG ACGCAGACTG 1740

AGGGGCCAGA AGAAGATTGG CAACCCTTTG CTACATCAGC ACAGGAAAAC TGTTTGTGTG 1800

TGC 1803

Domain Profile

S: 14    emedavtsspnflkspekkdr.....laffgvyDGhggsevakfcseklheilaeeless  68

           +da++++p++++sp+ + +     +aff+v+DGhgg+e+a+f++e+l+ ++++++ ++

Q: 68    RARDARDPAPDAGASPGGRCCrrrssVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFT  127

         45677788899999999877788999**********************************

S: 69    eseerkvkkalakaFlstdeel.....kvleeksldidksGstavvalikdsklyvanvG  123

         +se +kv++a++k+Fl+++ ++     +++++++  +++sG+ta+v++i+++k+yva+vG

Q: 128   SSEPAKVCAAIRKGFLACHLAMwkklaEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVG  187

         ************************************************************

S: 124   dSravLcrngk.......avelssdHkpsredEleRieeaggsvilkdga.Rv.......  168

         dS++vL+ +++       ave+++dHkp+ ++E+eRie  ggsv++k+g+ Rv

Q: 188   DSGVVLGIQDDpkndfvrAVEVTQDHKPELPKERERIEGLGGSVMNKSGVnRVvwkrprl  247

         ********77656999999*****************************************

S: 169   ..............lGvLavsRalGdlylk......pyvtpePevtshrltsede.fliL  207

                       +++Lav+RalGdl+++      ++v+peP++++h+l+++++ ++iL

Q: 248   thsgpvrrstvidqIPFLAVARALGDLWSYdffsgeFVVSPEPDTSVHTLDPQKHkYIIL  307

         ************************************************************

S: 208   asDGlwdvvsneeavslvrdvle....kkeaeqeaakkLvklalargsk.....dnvsai  258

         +sDGlw+++++++avs+++d++e    ++e+ q++ak+Lv++al r+++     dn+sai

Q: 308   GSDGLWNMIPPQDAVSMCQDQEEkkylTGEHGQSCAKMLVNRALGRWRQrmlraDNTSAI  367

         ***********************99999********************************

S: 259   vv  260

v+

Q: 368   VI  369

Domain Sequence
(FASTA)

RARDARDPAP DAGASPGGRC CRRRSSVAFF AVCDGHGGRE AAQFAREHLW GFIKKQKGFT 60

SSEPAKVCAA IRKGFLACHL AMWKKLAEWP KTMTGLPSTS GTTASVVIIR GMKMYVAHVG 120

DSGVVLGIQD DPKNDFVRAV EVTQDHKPEL PKERERIEGL GGSVMNKSGV NRVVWKRPRL 180

THSGPVRRST VIDQIPFLAV ARALGDLWSY DFFSGEFVVS PEPDTSVHTL DPQKHKYIIL 240

GSDGLWNMIP PQDAVSMCQD QEEKKYLTGE HGQSCAKMLV NRALGRWRQR MLRADNTSAI 300

VI 302

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>