EKS-CAP-00232

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00232

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	510.8	6.9E-154	4	287	284

Status

Unreviewed

Ensembl Protein

ENSCPOP00000000350

UniProt Accession

H0UTU6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000000399	ENSCPOP00000000350	ENSCPOT00000000402

Organism

Cavia porcellus

Functional Description

Protein Length

558

Protein Sequence
(FASTA)

MEKYENLGLV GEGSYGMVMK CRDKDSGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 60

ENLVNLLEVC KKKKRWYLIF EFVDHTILDD LELFPNGLDY QVVQKYLFQI INGIGFCHSH 120

NIIHRDIKPE NILVSQAGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDVKYG 180

KAVDVWAIGC LVTEMLTGEP LFPGDSDIDQ LYHIVTCLGN LIPRHQELFY KNPAFTGVRL 240

PEIQETEPLE RRYPKLSEVV MDLAKKCLHT DPDRRPLCAE LLSHTFFQAD KFAERFSQEL 300

QLKIQKEARN ISLPKRVKMP GKGANSALGK RRGFINGQDA NADAKTKDPK VCKTKGSKVD 360

GEKAEKGTRT ANASCLRNSG TSHMQAAPSD CLGDRGSQAT KVPGTAIPPL AHTPSAAAPG 420

GHPGAQSYRV DEKTKKYCIP FVKPNKHCPS GIYNISVPAQ VSSEKNLLQA SRKRREYSRT 480

EVRLPELSYS HLPDLRALEG MARNSRLIRK ENKILSESRI PSLAAIDLHA SSMALHQVLG 540

SPLSEDTEAN APWVEHQH 558

Nucleotide Sequence
(FASTA)

ATGGAAAAAT ATGAAAACCT AGGTTTGGTT GGAGAAGGAA GCTACGGAAT GGTGATGAAG 60

TGTAGGGATA AAGACAGCGG GAGGATTGTG GCCATCAAGA AGTTCTTAGA AAGTGATGAT 120

GACAAAATGG TTAAAAAAAT TGCCATGCGA GAGATCAAGT TACTGAAGCA ACTGAGGCAT 180

GAGAATTTGG TTAATCTGTT GGAAGTGTGT AAGAAGAAAA AAAGATGGTA CCTGATCTTT 240

GAATTTGTTG ATCACACAAT TCTGGATGAC TTGGAACTCT TTCCAAATGG ACTGGACTAC 300

CAAGTAGTGC AGAAGTATTT GTTTCAGATT ATTAATGGAA TTGGCTTTTG TCACAGTCAC 360

AATATCATAC ACAGGGACAT AAAGCCAGAG AACATCTTGG TGTCCCAGGC TGGTGTGGTG 420

AAGCTGTGTG ACTTTGGGTT TGCGCGCACG CTGGCTGCAC CCGGGGAGGT GTACACAGAC 480

TACGTGGCCA CCAGGTGGTA CAGGGCGCCA GAGCTTCTGG TTGGAGATGT CAAGTACGGC 540

AAGGCTGTCG ATGTCTGGGC TATTGGTTGT CTGGTAACAG AGATGCTCAC GGGGGAGCCC 600

CTGTTTCCGG GAGACTCTGA CATTGACCAG CTCTACCACA TTGTGACGTG TTTAGGTAAT 660

TTAATTCCAA GACATCAAGA GCTGTTTTAT AAAAATCCTG CATTTACCGG AGTACGACTG 720

CCTGAAATTC AAGAAACAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTTGTG 780

ATGGATTTAG CGAAGAAATG CTTGCACACT GACCCTGACA GAAGGCCACT GTGTGCTGAG 840

CTCCTGAGCC ACACTTTCTT CCAGGCGGAC AAGTTTGCCG AGAGATTTTC CCAGGAACTA 900

CAGTTAAAAA TACAGAAAGA GGCCAGGAAT ATTTCTTTGC CAAAGAGAGT AAAGATGCCA 960

GGGAAAGGGG CAAATTCTGC TCTAGGTAAA AGAAGAGGTT TTATTAATGG TCAGGATGCC 1020

AATGCTGATG CCAAGACTAA AGATCCCAAA GTGTGTAAAA CAAAAGGGTC CAAAGTTGAT 1080

GGAGAGAAAG CTGAAAAGGG TACGAGAACT GCCAATGCCA GCTGTCTTCG GAACAGTGGG 1140

ACCAGCCACA TGCAGGCAGC GCCCTCAGAC TGCCTTGGGG ACCGTGGCAG CCAGGCCACC 1200

AAGGTCCCAG GCACTGCCAT TCCTCCGCTG GCGCACACTC CATCTGCAGC GGCCCCTGGT 1260

GGTCACCCCG GAGCCCAGAG TTACAGAGTG GATGAGAAAA CTAAGAAGTA TTGCATTCCA 1320

TTTGTTAAGC CAAATAAACA CTGTCCGTCA GGAATTTATA ATATCAGTGT GCCCGCACAG 1380

GTCTCCAGTG AGAAGAACTT GCTTCAGGCA AGCAGGAAGC GAAGGGAGTA CTCCAGGACA 1440

GAGGTGCGAC TGCCTGAGCT GAGCTACAGC CACCTGCCCG ATCTGCGCGC CTTGGAAGGC 1500

ATGGCTCGAA ATTCTAGACT AATAAGGAAA GAGAACAAAA TTCTTTCTGA ATCTCGAATC 1560

CCTTCTCTGG CTGCTATTGA CCTTCATGCC TCCAGCATGG CACTGCACCA GGTGCTGGGC 1620

TCACCCCTGT CCGAAGACAC CGAGGCCAAC GCGCCCTGGG TGGAGCACCA GCACTGA 1677

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcr+kd+g+ivaikkfles+ddk+vkkia+reikllkql+henl

Q: 4     YENLGLVGEGSYGMVMKCRDKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++yl+fe+vd+t+ld+le +pnG+++++v+k+l+qi+++i fch++nii

Q: 64    VNLLEVCKKKKRWYLIFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+ gvvklcdfGfar+laapg+vytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILVSQAGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl++e+ltGeplfpg+sd+dqly+i+++lG+liprhq++f+kn+ f+Gv+lpe+

Q: 184   DVWAIGCLVTEMLTGEPLFPGDSDIDQLYHIVTCLGNLIPRHQELFYKNPAFTGVRLPEI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++e+le++ypkl+ev++dl+kkcl+ dp++r +c+ell+h++f

Q: 244   QETEPLERRYPKLSEVVMDLAKKCLHTDPDRRPLCAELLSHTFF  287

         *****************************************998

Domain Sequence
(FASTA)

YENLGLVGEG SYGMVMKCRD KDSGRIVAIK KFLESDDDKM VKKIAMREIK LLKQLRHENL 60

VNLLEVCKKK KRWYLIFEFV DHTILDDLEL FPNGLDYQVV QKYLFQIING IGFCHSHNII 120

HRDIKPENIL VSQAGVVKLC DFGFARTLAA PGEVYTDYVA TRWYRAPELL VGDVKYGKAV 180

DVWAIGCLVT EMLTGEPLFP GDSDIDQLYH IVTCLGNLIP RHQELFYKNP AFTGVRLPEI 240

QETEPLERRY PKLSEVVMDL AKKCLHTDPD RRPLCAELLS HTFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013