EKS-CAP-00227

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00227

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	517.7	7.3E-156	4	284	281

Status

Unreviewed

Ensembl Protein

ENSCPOP00000000654

UniProt Accession

H0UUK9;

Protein Name

Protein Synonyms/Alias

Gene Name

ICK

Gene Synonyms/Alias

ICK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000000735	ENSCPOP00000000654	ENSCPOT00000000740

Organism

Cavia porcellus

Functional Description

Protein Length

633

Protein Sequence
(FASTA)

MNRYTTIKQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 120

FFHRDLKPEN LLCMGPELVK IADFGLAREI RSRPPYTDYV STRWYRAPEV LLRSTNYSSP 180

IDVWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK KTDWPEGYQL SSAMNFRWPQ 240

CIPNNLKTLI PNASSEAIQL LRDMLQWDPK KRPTASQALR YPYFQIGHLL GITAQNLQDS 300

GKPQKDVPEK TGPPPHIKPV PPAQPPAKPH ARISSRQHHA GQAPQHLLYP YKAEASRTDH 360

PSHVQEDKPS PLLLPSLHNK NPQPKILAGL EHKNGEIKPK SRRRWGLISR STKDSDDWTD 420

LDDLDFSPSL SRIDLKSKKR QSDDALCRFE SILDLKPSEP VGTGSSAPTQ TSYPRRDTPT 480

LRSAAKQHYL QHSRYLPGNN IRNGVLPNPG KDFLPSNSWS SSGLSGKSSG TVSVISKINS 540

AVGSSSTSSS GLTGNYIPSF LKKEIGSALP RVHLAPIPDP PPGYSSLKAV RPLPGRPFFH 600

TQPRSTPGLK PRPPAAQPVH GRTDWASKYP SRR 633

Nucleotide Sequence
(FASTA)

ATGAATAGAT ACACAACGAT TAAGCAGCTT GGGGATGGGA CCTACGGTTC TGTCCTGCTC 60

GGAAGAAGCA TTGAGTCTGG GGAACTGATT GCCATTAAAA AAATGAAAAG GAAGTTTTAT 120

TCCTGGGAGG AATGCATGAA CCTTCGTGAG GTTAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTAA AATTAAAAGA AGTTATCAGG GAAAATGATC ATCTTTATTT TATCTTTGAG 240

TACATGAAGG AAAATCTTTA CCAGCTCATT AAAGAAAGAA ATAAGTTGTT TCCAGAGTCT 300

GCTATTCGGA ATATTATGTA TCAGATATTG CAAGGACTGG CGTTTATTCA CAAACACGGC 360

TTCTTCCATC GGGACCTGAA GCCCGAGAAC CTCCTCTGCA TGGGACCAGA GCTGGTGAAA 420

ATCGCAGACT TTGGGTTGGC CCGAGAAATC CGATCAAGGC CTCCCTACAC AGACTACGTG 480

TCTACCCGAT GGTACAGGGC TCCGGAAGTC CTCCTGCGGT CCACCAACTA CAGCTCCCCC 540

ATCGACGTCT GGGCGGTGGG CTGCATCATG GCGGAGGTGT ACACCCTCAG ACCACTCTTC 600

CCTGGGGCCA GTGAAATTGA CACGATATTC AAAATTTGCC AAGTGTTGGG GACACCAAAA 660

AAGACGGACT GGCCGGAGGG CTACCAACTT TCAAGTGCGA TGAACTTCCG CTGGCCCCAG 720

TGCATTCCCA ATAATTTAAA GACCCTGATT CCAAATGCTA GCAGCGAAGC CATTCAGCTC 780

CTGAGAGACA TGCTCCAGTG GGACCCTAAG AAACGGCCAA CAGCTAGCCA GGCTCTTAGG 840

TATCCCTACT TCCAGATTGG ACACCTGCTG GGCATCACCG CCCAGAATCT GCAGGACTCA 900

GGAAAGCCAC AGAAGGATGT CCCAGAAAAG ACGGGCCCAC CCCCACACAT CAAGCCGGTC 960

CCTCCTGCCC AGCCCCCAGC CAAGCCACAT GCACGAATTT CTTCCCGGCA GCATCACGCC 1020

GGCCAGGCCC CTCAGCATCT CCTGTACCCC TACAAAGCAG AGGCCTCCAG GACAGATCAC 1080

CCGAGCCATG TTCAGGAGGA CAAGCCAAGC CCACTGCTTC TCCCGTCCCT CCACAACAAG 1140

AACCCTCAGC CGAAAATCCT AGCTGGCCTG GAGCACAAAA ACGGTGAGAT CAAGCCAAAG 1200

AGCAGGAGAA GGTGGGGCCT TATTTCCAGG TCCACTAAGG ATTCGGATGA CTGGACCGAC 1260

CTGGATGACT TGGACTTCAG TCCGTCCCTC AGCAGGATCG ACCTGAAAAG CAAGAAGCGA 1320

CAGAGTGACG ATGCTCTCTG CAGATTTGAG AGCATTTTGG ACCTGAAGCC CTCCGAACCT 1380

GTGGGTACCG GAAGTAGCGC CCCCACGCAG ACCTCGTACC CGCGGCGAGA CACGCCCACC 1440

CTGAGGTCCG CAGCCAAGCA GCATTACCTG CAGCACTCGC GATACCTGCC CGGTAATAAC 1500

ATAAGAAACG GCGTGCTCCC AAATCCAGGG AAGGACTTTC TTCCATCGAA TTCATGGTCC 1560

AGTTCTGGCT TGTCTGGAAA GTCTTCTGGG ACAGTATCAG TAATCAGCAA AATAAATTCA 1620

GCAGTTGGTT CCAGCTCTAC AAGTTCTAGT GGACTGACTG GCAATTACAT CCCTTCCTTT 1680

CTGAAAAAAG AAATTGGTTC TGCTCTGCCG AGGGTACACT TGGCACCTAT TCCAGACCCT 1740

CCCCCTGGCT ATTCTTCCCT GAAGGCCGTG AGACCCCTTC CTGGGCGACC TTTCTTCCAC 1800

ACTCAGCCAA GAAGCACCCC TGGCTTGAAA CCCCGGCCTC CAGCCGCCCA GCCAGTGCAC 1860

GGCCGGACAG ACTGGGCTTC CAAGTACCCG TCTCGGCGGT GA 1902

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++ik+lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+++e+m+enlyqlik+r+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavGc++aev++lrplfPGaseid+ifki++vlGtPkk++w+e+y+l+sa+n+++pq

Q: 181   IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++ll+d+l++dP++r+ta+qal+ypyf

Q: 241   CIPNNLKTLIPNASSEAIQLLRDMLQWDPKKRPTASQALRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTIKQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFIFEYMK ENLYQLIKER NKLFPESAIR NIMYQILQGL AFIHKHGFFH 120

RDLKPENLLC MGPELVKIAD FGLAREIRSR PPYTDYVSTR WYRAPEVLLR STNYSSPIDV 180

WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC QVLGTPKKTD WPEGYQLSSA MNFRWPQCIP 240

NNLKTLIPNA SSEAIQLLRD MLQWDPKKRP TASQALRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013