EKS-CAP-00228

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00228

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	508.8	3.8E-153	4	284	281

Status

Unreviewed

Ensembl Protein

ENSCPOP00000001528

UniProt Accession

H0UWT3;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000001694	ENSCPOP00000001528	ENSCPOT00000001715

Organism

Cavia porcellus

Functional Description

Protein Length

622

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHV 60

NVIKLKEVIR ENNHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPDLVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASSEAIHL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GPSLNHLESK 300

QSSNKQLQPV DSKPTSAEME PKTLPDVSDQ PVGPPQPKHS HQPLQSIQLL QNVGTPPPPK 360

QQGQQKAPLF PSIIKNVPAK PSGTLGHKTA RRRWGQAVFK SGDSWEEFED GDLGASHSKK 420

PSIGVFKEKR KKDPPFRLQE SGLMGANHPP RDPKSVPAAV SLKSDSELAA VSAPKQYYLK 480

QSRYLPGVNP KRVSLRAAGK DVNSYAWNNQ LFPKSLGAVG AEVAFQRNNA GNLGGYTTYS 540

QSGYIPSFLK KEVGSAGQRI HLAPLGAAAA TEFSWSTKPG HGQFSRPAYS PGTKNLPIVM 600

GAPPVPSVPA RTDWAAKYGG HR 622

Nucleotide Sequence
(FASTA)

ATGAACCGCT ACACAACCAT GCGGCAGCTG GGGGATGGCA CCTATGGGAG CGTGCTGATG 60

GGCAAGAGTA ACGAGTCCGG GGAGCTGGTG GCCATCAAGA GAATGAAGAG GAAGTTCTAC 120

TCTTGGGATG AATGCATGAA CCTGAGAGAA GTTAAGTCTC TGAAGAAGCT TAACCATGTC 180

AACGTGATTA AACTGAAAGA AGTTATCAGA GAAAATAACC ATCTTTATTT TATATTTGAG 240

TATATGAAAG AAAATCTCTA TCAGCTAATG AAAGACAGAA ACAAACTGTT CCCAGAGTCA 300

GTCATCAGAA ACATTATGTA TCAGATATTG CAAGGGCTGG CATTTATCCA TAAGCATGGC 360

TTTTTTCACA GGGACATGAA ACCAGAAAAC TTGCTTTGTA TGGGGCCAGA CCTTGTGAAA 420

ATCGCAGATT TTGGACTTGC AAGAGAATTA AGGTCACAGC CACCGTACAC TGATTATGTG 480

TCTACCAGAT GGTACCGAGC TCCTGAGGTT CTGCTGAGAT CGTCAGTGTA CAGTTCTCCC 540

ATCGACGTGT GGGCCGTGGG AAGCATCATG GCAGAGCTGT ACACGTTGAG ACCGCTCTTC 600

CCGGGGACAA GTGAGGTTGA TGAAATCTTT AAAATCTGCC AAGTGTTAGG GACTCCCAAA 660

AAAAGCGACT GGCCAGAAGG ATACCAGCTT GCCTCCTCCA TGAATTTCCG ATTTCCCCAG 720

TGTGTTCCCA TCAACTTAAA AACTCTCATT CCCAACGCCA GCAGTGAAGC CATTCACCTG 780

ATGACCGAGA TGCTGAACTG GGACCCAAAG AAACGTCCAA CCGCAAGCCA GGCACTGAAA 840

CACCCCTATT TCCAAGTTGG CCAAGTGTTA GGCCCTTCCT TGAACCATCT GGAATCCAAA 900

CAGTCTTCAA ATAAGCAGCT GCAGCCGGTG GACTCAAAGC CTACGTCAGC TGAAATGGAA 960

CCTAAGACTC TGCCGGATGT AAGCGACCAG CCTGTCGGAC CGCCCCAGCC AAAGCACAGC 1020

CACCAGCCTC TGCAGTCCAT TCAGCTTCTG CAGAACGTGG GAACCCCGCC ACCCCCAAAG 1080

CAACAGGGTC AACAGAAAGC ACCACTGTTC CCAAGCATCA TCAAAAACGT GCCGGCTAAG 1140

CCCAGCGGCA CACTGGGTCA CAAAACCGCC AGGAGGCGCT GGGGTCAGGC TGTCTTCAAG 1200

TCTGGGGACA GCTGGGAGGA GTTTGAGGAT GGTGATCTCG GAGCCTCCCA TTCCAAGAAG 1260

CCAAGCATTG GTGTTTTCAA AGAAAAGAGG AAAAAAGATC CTCCCTTTCG GCTTCAGGAG 1320

TCAGGACTCA TGGGCGCCAA CCACCCGCCC AGGGACCCCA AGAGCGTGCC TGCCGCTGTC 1380

TCTCTCAAAT CCGATTCTGA ACTGGCAGCT GTGTCAGCAC CTAAGCAGTA CTACTTGAAA 1440

CAGTCAAGAT ACCTCCCAGG TGTAAATCCC AAGCGTGTGT CTCTCCGAGC CGCCGGGAAG 1500

GACGTCAACT CTTACGCCTG GAATAATCAG CTGTTTCCCA AGTCTCTGGG AGCCGTGGGA 1560

GCAGAAGTCG CTTTCCAAAG GAATAATGCA GGAAATCTCG GCGGTTACAC TACTTACAGC 1620

CAGTCAGGAT ACATCCCTTC CTTCCTCAAA AAAGAAGTTG GGTCAGCCGG CCAGAGGATC 1680

CACTTGGCGC CCCTTGGCGC CGCAGCTGCT ACAGAATTCA GCTGGAGCAC GAAGCCTGGC 1740

CACGGGCAGT TTTCGAGGCC CGCGTACAGC CCGGGCACCA AGAACCTCCC CATCGTGATG 1800

GGCGCCCCGC CGGTGCCCTC AGTGCCCGCG AGGACGGACT GGGCGGCCAA GTATGGGGGC 1860

CACCGC 1866

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HVNV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  ren++ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENNHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g++lvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPDLVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l++++l++dP++r+ta+qalk+pyf

Q: 241   CVPINLKTLIPNASSEAIHLMTEMLNWDPKKRPTASQALKHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHVNVI 60

KLKEVIRENN HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPDLVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SSEAIHLMTE MLNWDPKKRP TASQALKHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013