EKS-CAP-00258

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00258

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	428.4	9.3E-129	42	302	261

Status

Unreviewed

Ensembl Protein

ENSCPOP00000001681

UniProt Accession

H0UX75;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000001856	ENSCPOP00000001681	ENSCPOT00000001877

Organism

Cavia porcellus

Functional Description

Protein Length

380

Protein Sequence
(FASTA)

MDGETAEKGG PAFPPGALGE SGVGGAPTRR EPKKYAVTDD YQLSKQVLGL GVNGKVLECF 60

HRRTGQKCAL KLLYDSPKAR QEVDHHWQAS GGPHIVRIID VYENMHHGKR CLLIIMECME 120

GGELFSRIQE RGDQAFTERE AAGIMRDIGT AIQFLHSQNI AHRDVKPENL LYTSKEKDAV 180

LKLTDFGFAK ETTQNALQTP CYTPYYVAPE VLGPEKYDKS CDMWSLGVIM YILLCGFPPF 240

YSNTGQAISP GMKKRIRQGQ YGFPNPEWSE VSENAKQLIR LLLKTDPTER LTIMQFMNHP 300

WINQSMVVPQ TPLYTARVLQ EDKDHWDEVK EEMTSALATI RVDYDQVKIK DLKTSNNRLL 360

NKRRKKQAGS SSTSQGCNNQ 380

Nucleotide Sequence
(FASTA)

ATGGATGGCG AGACTGCGGA GAAGGGCGGC CCTGCATTCC CACCTGGGGC CCTCGGTGAA 60

TCCGGAGTGG GTGGTGCTCC AACGCGGAGG GAGCCCAAGA AGTATGCCGT TACCGATGAC 120

TACCAGTTAT CTAAGCAGGT GCTGGGTCTA GGAGTCAACG GCAAGGTGCT GGAGTGCTTC 180

CATCGGCGCA CTGGGCAGAA ATGTGCCTTG AAGCTCCTGT ACGATAGCCC CAAGGCCCGG 240

CAGGAGGTGG ACCATCACTG GCAGGCCTCG GGTGGCCCCC ACATTGTGCG CATCATAGAT 300

GTGTATGAGA ATATGCATCA CGGCAAGCGC TGCCTCCTCA TCATCATGGA ATGCATGGAA 360

GGTGGTGAAT TGTTCAGCAG GATTCAGGAG CGTGGCGACC AGGCATTCAC CGAGAGAGAG 420

GCTGCAGGGA TAATGCGGGA CATTGGCACT GCCATTCAGT TCCTGCACAG TCAGAACATC 480

GCCCACCGAG ATGTCAAGCC TGAAAACCTG CTCTACACAT CCAAAGAGAA AGATGCTGTG 540

CTTAAGCTCA CTGACTTTGG CTTTGCCAAG GAGACCACCC AAAATGCCTT ACAGACACCT 600

TGCTACACGC CCTACTATGT GGCCCCTGAG GTCCTGGGTC CAGAGAAGTA TGACAAGTCC 660

TGTGACATGT GGTCCCTGGG GGTCATCATG TACATCCTCC TGTGTGGCTT CCCACCTTTC 720

TATTCCAACA CGGGCCAGGC CATCTCCCCA GGGATGAAGA AGAGGATCCG CCAGGGCCAG 780

TACGGCTTCC CCAATCCTGA GTGGTCCGAG GTCTCTGAGA ATGCCAAGCA GCTGATTCGT 840

CTACTGCTGA AGACGGACCC TACAGAGAGA CTGACCATTA TGCAGTTTAT GAACCATCCG 900

TGGATAAATC AATCAATGGT GGTGCCACAG ACTCCGCTCT ACACAGCCCG AGTACTGCAG 960

GAGGACAAAG ACCACTGGGA TGAAGTCAAG GAGGAGATGA CTAGTGCCCT GGCCACCATT 1020

CGGGTGGACT ATGACCAGGT GAAGATCAAA GACCTGAAGA CCTCTAATAA CCGGCTACTC 1080

AACAAGCGGA GAAAAAAACA GGCAGGCAGC TCCTCAACTT CACAGGGCTG CAATAACCAG 1140

TAG 1143

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         +l+++vlG G++gkvlec++++tg+k+alk+l+d++k+r+ev++h+qasg ++iv++idv

Q: 42    QLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRIIDV  101

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++++ll+++e++eGGel+sriqer  +afte+ea+ +++di++a++flhs+nia

Q: 102   YENMHHGKRCLLIIMECMEGGELFSRIQERgdQAFTEREAAGIMRDIGTAIQFLHSQNIA  161

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+skek+a++kl+Dfg+ake +++++l+tpc+t++yvaPevl++ek

Q: 162   HRDVKPENLLYTSKEKDAVLKLTDFGFAKE-TTQNALQTPCYTPYYVAPEVLGPEK----  216

         *****************************7.7899*********************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri++g+y fP++eWsevse+a

Q: 217   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKKRIRQGQYGFPNPEWSEVSENA  275

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+lir lLk+dp+erlti++++nhpw+

Q: 276   KQLIRLLLKTDPTERLTIMQFMNHPWI  302

         **************************8

Domain Sequence
(FASTA)

QLSKQVLGLG VNGKVLECFH RRTGQKCALK LLYDSPKARQ EVDHHWQASG GPHIVRIIDV 60

YENMHHGKRC LLIIMECMEG GELFSRIQER GDQAFTEREA AGIMRDIGTA IQFLHSQNIA 120

HRDVKPENLL YTSKEKDAVL KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKKRIRQGQY GFPNPEWSEV SENAKQLIRL 240

LLKTDPTERL TIMQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013