EKS-CAP-00378

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00378

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DCAMKL	437.1	2.1E-131	353	610	258

Status

Unreviewed

Ensembl Protein

ENSCPOP00000002071

UniProt Accession

H0UY70;

Protein Name

Protein Synonyms/Alias

Gene Name

DCLK3

Gene Synonyms/Alias

DCLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000002280	ENSCPOP00000002071	ENSCPOT00000002312

Organism

Cavia porcellus

Functional Description

Protein Length

645

Protein Sequence
(FASTA)

MGKEPLTLKN IQMAIEELYP NKNRALTVTQ HSRASSPRLR SRLYSKVLKG GHHCGETGSG 60

TESAQGKAII RRQGKSPMEP ALQDKVRAQK KWMRGKQKPE SGSKLSRETT LEERHASGEK 120

HLGLEIEKTS GEIVRCEKCK RERERQQSLQ HERLSLGTSE LDMGKCQRYE VEKLVRTKSY 180

RRSPEANPAH GGEGRKVDSH RSSPRNPTHE LHRLSKNTDM KEDRDPEDQA SHPQGAARIK 240

KELMEVPPET EEGPRDVQKD IRHVCKSKHS ISLLREHQPE LEKLSKTRRE EKEAENEKKP 300

GVSGARKIAV RDDPPARIEK EPKTRPEENK SKRSTGWKPR PAGIITADVG KHYETGRVIG 360

DGNFAVVKEC RHRETRQAYA MKIIDKSKLK GKEDIIDSEI LIIQSLSHPN IVKLHEVYEM 420

EMEICLIMEY VQGGDLFDAI IESVKFPEPD AARLIMDLCK ALVHMHDKNI VHRDLKPENL 480

LVQRNEDKST TLKLADFGLA KHVVRPVFTV CGTPTYVAPE ILSEKGYGLE VDMWAAGVIL 540

YILLCGFPPF RSPERDQDEL FNIIQLGNFE FLAPYWDNIS DAAKDLVSRL LVVDPKKRYT 600

AHQVLQHPWI ETAGKISRVD PQKEVSSSSE GHSWSQHKRI MEQAS 645

Nucleotide Sequence
(FASTA)

ATGGGCAAAG AACCCTTGAC ATTGAAGAAC ATTCAAATGG CTATTGAGGA ACTGTATCCT 60

AACAAAAACC GGGCACTGAC AGTGACCCAG CATAGCCGAG CCTCTTCTCC AAGGCTGAGA 120

AGCAGACTTT ATAGCAAGGT TCTGAAAGGG GGCCACCACT GTGGGGAGAC TGGGAGTGGC 180

ACTGAGTCCG CCCAGGGCAA GGCAATCATC AGGCGTCAGG GAAAGTCCCC CATGGAGCCT 240

GCACTGCAAG ACAAGGTGAG GGCCCAGAAG AAGTGGATGA GGGGGAAACA GAAGCCTGAA 300

TCTGGTAGCA AGCTGTCCAG AGAAACCACT CTGGAGGAGA GGCATGCCAG TGGAGAGAAG 360

CACCTGGGGC TGGAGATTGA AAAGACCTCT GGGGAGATTG TCCGATGTGA GAAGTGCAAG 420

CGAGAACGGG AGCGCCAGCA GAGCCTACAG CACGAGAGGC TTTCCCTGGG CACCAGTGAG 480

CTGGACATGG GCAAGTGCCA GAGGTATGAA GTGGAGAAGC TGGTGAGGAC AAAGAGCTAT 540

AGGAGGTCTC CAGAGGCAAA CCCTGCACAT GGTGGGGAAG GGCGCAAGGT TGACAGCCAT 600

AGGAGCAGTC CCAGGAATCC CACACATGAG CTGCACAGAC TTAGCAAGAA CACGGATATG 660

AAAGAGGACA GAGACCCGGA GGATCAAGCA AGCCATCCTC AGGGAGCAGC CAGGATCAAG 720

AAGGAGCTCA TGGAAGTGCC TCCAGAGACA GAGGAGGGGC CCAGGGATGT ACAGAAAGAC 780

ATCAGGCATG TTTGCAAGAG CAAGCATAGT ATCTCTCTGC TGAGAGAGCA CCAGCCTGAG 840

CTAGAGAAGC TCTCTAAAAC CCGAAGAGAA GAAAAGGAAG CAGAGAATGA GAAGAAGCCT 900

GGCGTGTCAG GAGCGAGGAA GATAGCTGTC AGAGATGACC CCCCTGCAAG GATAGAGAAG 960

GAGCCCAAGA CCAGACCAGA AGAGAACAAG TCAAAACGGT CCACTGGCTG GAAGCCGCGG 1020

CCTGCAGGCA TCATCACGGC GGATGTAGGG AAGCATTATG AGACTGGACG GGTCATTGGG 1080

GATGGAAATT TTGCCGTGGT GAAGGAGTGC AGGCACCGTG AGACCAGGCA GGCGTATGCC 1140

ATGAAAATTA TCGACAAGTC CAAACTCAAG GGTAAGGAGG ACATAATTGA CAGTGAGATC 1200

TTAATCATTC AGAGCCTTTC TCACCCCAAC ATAGTGAAAC TGCATGAAGT ATATGAAATG 1260

GAAATGGAAA TCTGCTTGAT CATGGAGTAT GTACAGGGAG GGGACCTTTT CGACGCCATT 1320

ATAGAAAGTG TGAAGTTCCC TGAGCCCGAT GCAGCACGCT TGATCATGGA CCTATGTAAG 1380

GCCCTCGTCC ATATGCATGA CAAGAATATT GTCCACCGGG ACCTCAAGCC AGAAAATCTC 1440

TTGGTTCAAC GAAATGAGGA CAAATCTACC ACTTTGAAAC TAGCTGATTT TGGCCTTGCA 1500

AAACATGTAG TGAGACCTGT ATTTACTGTG TGTGGAACTC CAACATATGT AGCTCCTGAA 1560

ATTCTTTCTG AGAAAGGTTA TGGCTTGGAA GTGGACATGT GGGCTGCTGG CGTGATCCTC 1620

TACATCCTCC TGTGTGGCTT CCCTCCATTC CGCAGCCCAG AGAGGGACCA GGATGAACTC 1680

TTTAATATCA TCCAGCTGGG CAACTTCGAG TTCCTTGCCC CTTACTGGGA CAATATCTCT 1740

GATGCTGCCA AAGATCTGGT AAGCCGATTG CTGGTGGTAG ATCCCAAAAA GCGCTACACG 1800

GCCCACCAGG TTCTTCAGCA TCCCTGGATT GAAACAGCTG GAAAGATCAG CAGGGTGGAC 1860

CCACAGAAGG AAGTGTCCTC CAGCAGTGAG GGCCATAGCT GGAGCCAGCA CAAGAGGATC 1920

ATGGAGCAGG CATCATAG 1938

Domain Profile

S: 1     yeigrviGdGnfavvkevreretgkeyalkiidksklkGkehlidneveilkkvkhpniv  60

         ye+grviGdGnfavvke+r+ret+++ya+kiidksklkGke++id+e+ i+++++hpniv

Q: 353   YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSKLKGKEDIIDSEILIIQSLSHPNIV  412

         89**********************************************************

S: 61    klieeletetelylvlelvkgGdlfdaitkstkleerdaaimilelakalkylhelnivh  120

         kl+e++e+e+e+ l++e+v+gGdlfdai++s+k++e+daa++i++l+kal ++h++nivh

Q: 413   KLHEVYEMEMEICLIMEYVQGGDLFDAIIESVKFPEPDAARLIMDLCKALVHMHDKNIVH  472

         ************************************************************

S: 121   rdvkpenllvvekedgskslkladfGlaaevegplytvcGtPtyvaPeilaetGyglkvd  180

         rd+kpenllv+++ed+s++lkladfGla++v +p++tvcGtPtyvaPeil+e+Gygl+vd

Q: 473   RDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPVFTVCGTPTYVAPEILSEKGYGLEVD  532

         ************************************************************

S: 181   iWaaGvilyillvGfpPfrssdedqeelfdlilsgklefpsPyWdnisdkakdlvsrlle  240

         +WaaGvilyill+GfpPfrs+++dq+elf++i+ g++ef +PyWdnisd+akdlvsrll

Q: 533   MWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGNFEFLAPYWDNISDAAKDLVSRLLV  592

         ************************************************************

S: 241   vdeekrltaeqilehpwv  258

         vd++kr+ta+q+l+hpw+

Q: 593   VDPKKRYTAHQVLQHPWI  610

         *****************8

Domain Sequence
(FASTA)

YETGRVIGDG NFAVVKECRH RETRQAYAMK IIDKSKLKGK EDIIDSEILI IQSLSHPNIV 60

KLHEVYEMEM EICLIMEYVQ GGDLFDAIIE SVKFPEPDAA RLIMDLCKAL VHMHDKNIVH 120

RDLKPENLLV QRNEDKSTTL KLADFGLAKH VVRPVFTVCG TPTYVAPEIL SEKGYGLEVD 180

MWAAGVILYI LLCGFPPFRS PERDQDELFN IIQLGNFEFL APYWDNISDA AKDLVSRLLV 240

VDPKKRYTAH QVLQHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013