EKS-CAP-00468

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00468

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	326.9	9.6E-98	4	254	251

Status

Unreviewed

Ensembl Protein

ENSCPOP00000002323

UniProt Accession

H0UYU6;

Protein Name

Protein Synonyms/Alias

Gene Name

STK36

Gene Synonyms/Alias

STK36;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000002553	ENSCPOP00000002323	ENSCPOT00000002587

Organism

Cavia porcellus

Functional Description

Protein Length

1313

Protein Sequence
(FASTA)

MDKYHVLEMI GEGSFGRVYK GRKKYSAQVV ALKFIPKLGR TEKELRNLQR EIEIMQGLRH 60

PNIVHMLDSF ETDKEVVVVT DYAEGELFQI LEDDGKLPEE QVQAIAAQLV SALYYLHSHR 120

ILHRDMKPQN ILLAKGGGIK LCDFGFARAM STNTMVLTSI KGTPLYMSPE LVEERPYDHT 180

ADLWSVGCIL YELAVGTPPF YTTSIFQLVN LIRKDPVRWP PSISPCFKNF LQGLLTKDPQ 240

QRLSWPDLLH HPFIAGRVTI ITEPAGSDLA TPFTSRLPPE LQVLKDEQAH QLAPKGSQSC 300

ILHQACKRMA EEAKQKKQQN TGPALEQEDK SNSMIPSTAP KVEVRATPEK SSVLAGVLTS 360

EMKSSCAECQ AGETPTAPRE NCITRDSEQA LPQLEPEVAS QQSTDAGDVE DEEPDSDSKW 420

QHLLETTKPI PVQLKAPLIL LCNPDFYQCI QSQLHETGGQ ILKGVLEGAT RILPALRVLS 480

SLLSSCSDSV LLYSFCREAG LPGLLLSLLR HSQESITIQQ QPWCGTFSRD LVAVIQAYFA 540

CTFNLERNQT GDSLQVFQEA ASLFLDLLGK LLVQPDDSEH LQRDSLMCFV VLCEAMDGNS 600

QATSKAFYSS LLTTQRAVLD GLLRGLTAPQ FPFHTPPGAL HVNQPLREQS EDLPRAISCA 660

LAAMCTAPVG LPSCWDAKEQ VSWHLANQLA EDSSQLWPSL ISGLRHPVLC LHLLKVLYSC 720

CHVNEHLCSL LGQESLALQS LLMLVQGKVK VVDWEESTEV ALYLLSLLAF RLQDLPSRME 780

KLGSEVAMLF THSHIVSLVI AAACLLGQLG QQGVTFDLQP KEWIAAATHA LSAPTEVRLT 840

LPGGCGFYDG LLILLLQLLT KQGKAGLIHD VASSEILTVL WHRFSMVLKL PDKVSTQEED 900

LSLSGPPSPE PDWTLISPQG MAVLLSLAMA TFTQEPQLCL SHLSKRRSDL MSTLKYLLSP 960

SFLHHLSQAP HGPEFLPVVA LSVCQLFCFP FSLDVDADHL VGILADLRDA EVAALVLQVC 1020

CHHLPPSQVE LPISLLTRLA LMDSTCLNQF VSTVAASPEN ISFLSVALLS DQPLLTSDLL 1080

SLLAHAARVL SPSHLFFIQE LLAGSDESYR PLRILLGHPE NSVRARAFGL LGYLLQHSMA 1140

LRGALQSQAG LLKLLLLGLG DQDPAVRRNA SFAVGNAAYQ AGPLGPALAA AVPNMAQLLE 1200

DAQAGIRRNA ASALGNLGPE GLGEELLQCQ VPQRLLEMAC GDPQPNVKEA ALIALRSLQQ 1260

QPCIHEVLVS LGASEKLALL ALGNQLLVQN SSGLASARHC KKLIRLLKPP DST 1313

Nucleotide Sequence
(FASTA)

ATGGACAAGT ACCACGTGTT GGAGATGATT GGAGAAGGCT CTTTTGGGAG AGTGTACAAG 60

GGTCGAAAAA AATACAGTGC TCAGGTGGTG GCGCTGAAGT TCATCCCCAA ACTGGGCCGC 120

ACAGAGAAGG AGCTGAGGAA TCTGCAGCGA GAGATTGAAA TCATGCAGGG CCTTCGTCAT 180

CCCAACATTG TGCACATGCT TGACAGCTTT GAAACTGACA AAGAGGTGGT GGTAGTGACA 240

GACTATGCTG AGGGAGAGCT TTTTCAGATC CTGGAAGATG ATGGAAAACT TCCTGAGGAG 300

CAGGTACAGG CCATTGCTGC CCAGTTAGTG TCAGCCCTGT ACTATTTGCA TTCCCATCGC 360

ATCCTACACC GAGACATGAA GCCTCAGAAT ATTCTTCTTG CCAAGGGTGG TGGCATCAAA 420

CTCTGTGACT TTGGATTTGC CCGGGCTATG AGCACCAATA CAATGGTGCT GACATCTATC 480

AAAGGTACAC CACTCTATAT GTCTCCAGAG CTAGTGGAAG AGCGACCATA TGACCACACA 540

GCGGACCTCT GGTCTGTGGG CTGCATTCTG TATGAGCTGG CTGTGGGAAC CCCTCCCTTC 600

TATACCACAA GCATCTTTCA GCTAGTCAAT CTCATTCGCA AGGACCCTGT ACGCTGGCCC 660

CCTTCCATCA GTCCTTGCTT CAAGAACTTC CTGCAGGGAC TGCTCACCAA GGACCCCCAG 720

CAGCGTCTGT CCTGGCCGGA CCTCTTGCAT CACCCCTTTA TTGCTGGTCG CGTCACCATA 780

ATAACAGAAC CAGCAGGCTC AGATTTGGCC ACCCCATTCA CCAGTCGCCT ACCCCCAGAA 840

CTTCAGGTCC TAAAGGACGA ACAGGCCCAT CAGCTGGCTC CCAAAGGCAG TCAGTCTTGC 900

ATCTTGCATC AGGCCTGTAA ACGCATGGCT GAGGAGGCCA AGCAGAAGAA ACAGCAGAAC 960

ACAGGACCTG CCCTTGAGCA AGAAGATAAA TCCAACAGCA TGATCCCCAG CACAGCCCCT 1020

AAGGTGGAGG TCAGGGCCAC TCCTGAAAAA TCGAGTGTCT TAGCTGGAGT CTTGACCTCA 1080

GAAATGAAGA GCAGTTGTGC TGAGTGCCAG GCTGGAGAGA CCCCCACTGC ACCTCGGGAA 1140

AACTGTATCA CCCGAGACTC TGAACAAGCA TTGCCACAGC TGGAGCCGGA GGTGGCGAGC 1200

CAGCAGAGCA CAGATGCAGG GGACGTAGAA GACGAGGAGC CAGACAGTGA CAGTAAATGG 1260

CAGCACCTCC TCGAGACCAC CAAGCCCATT CCTGTGCAGC TGAAGGCTCC TCTCATCCTG 1320

CTGTGCAATC CTGACTTCTA CCAGTGCATC CAGAGTCAGC TCCATGAGAC CGGAGGGCAG 1380

ATCCTGAAAG GTGTCCTGGA GGGTGCCACC CGCATCCTCC CTGCACTTCG GGTCCTGAGC 1440

AGTCTTCTGT CTAGTTGCAG TGACTCTGTC CTCTTGTATT CCTTCTGCCG GGAGGCAGGG 1500

CTGCCTGGGC TGCTGCTCAG TCTACTCAGG CACAGCCAAG AGAGCATCAC TATCCAGCAG 1560

CAACCTTGGT GTGGGACCTT TTCAAGGGAC CTGGTGGCTG TGATTCAGGC CTACTTTGCC 1620

TGCACCTTCA ATCTGGAGAG GAACCAGACA GGTGACAGCC TACAGGTGTT TCAGGAAGCT 1680

GCCAGCCTCT TTCTGGACCT GCTGGGGAAA CTGCTGGTGC AACCAGACGA TTCTGAGCAT 1740

CTGCAGAGGG ACAGCCTTAT GTGCTTTGTT GTCCTTTGTG AAGCCATGGA TGGAAACAGC 1800

CAGGCTACCT CCAAAGCCTT TTACTCCAGC CTGCTGACCA CACAGCGTGC CGTGTTGGAT 1860

GGGCTTCTTC GTGGCCTGAC AGCCCCACAG TTCCCCTTCC ACACACCTCC AGGGGCCCTG 1920

CATGTGAACC AGCCACTGCG GGAGCAAAGT GAGGATCTGC CTAGAGCCAT TTCCTGCGCC 1980

CTGGCAGCCA TGTGCACTGC TCCTGTGGGC CTGCCCAGCT GCTGGGATGC CAAGGAGCAG 2040

GTCTCTTGGC ATTTGGCAAA TCAGCTGGCT GAAGACAGCA GCCAACTCTG GCCATCCCTC 2100

ATCTCAGGCC TGCGACATCC TGTCCTATGT CTGCACCTTC TTAAGGTTCT CTACTCTTGC 2160

TGTCATGTCA ATGAGCACCT GTGCAGTCTT CTAGGGCAAG AGTCCCTGGC CTTGCAGTCA 2220

CTGTTGATGC TGGTCCAGGG CAAGGTGAAA GTAGTGGATT GGGAGGAGTC CACTGAAGTG 2280

GCCCTCTACC TCCTCTCCCT TCTTGCCTTT CGGCTCCAAG ATCTGCCTTC CAGGATGGAG 2340

AAGCTAGGCA GCGAGGTTGC TATGCTCTTT ACCCACTCAC ACATCGTTTC TCTTGTGATT 2400

GCAGCAGCCT GTCTTTTGGG ACAGCTTGGT CAGCAAGGGG TGACCTTTGA CCTCCAGCCC 2460

AAGGAGTGGA TCGCTGCAGC CACACATGCT CTGTCTGCCC CCACAGAGGT CCGGCTGACT 2520

CTGCCAGGTG GCTGTGGGTT CTATGATGGC CTTCTCATCC TTCTGCTGCA GCTGCTCACC 2580

AAGCAGGGGA AGGCTGGCCT GATCCATGAC GTGGCTAGCT CAGAAATATT GACTGTCCTG 2640

TGGCATCGCT TCTCCATGGT CTTGAAGCTG CCTGATAAGG TGTCTACACA GGAAGAGGAC 2700

TTGTCATTGT CTGGTCCACC CAGTCCAGAG CCAGACTGGA CACTGATCTC ACCCCAGGGC 2760

ATGGCAGTCC TGCTGAGCCT GGCCATGGCC ACCTTCACCC AAGAGCCCCA GTTATGCCTC 2820

AGCCACCTGT CCAAGCGTAG AAGTGACCTC ATGTCCACCT TGAAGTACCT GCTTTCCCCC 2880

AGTTTCTTAC ATCACCTGAG CCAGGCGCCT CATGGGCCTG AGTTTCTTCC TGTCGTGGCA 2940

CTCTCTGTCT GCCAGCTCTT CTGCTTCCCC TTCTCCCTGG ATGTGGATGC CGACCACCTT 3000

GTAGGAATCT TGGCTGACCT CAGGGATGCA GAAGTTGCAG CCCTCGTGCT GCAGGTCTGC 3060

TGCCATCATC TTCCACCATC ACAAGTCGAG CTACCCATCA GCCTCCTCAC ACGCCTGGCC 3120

CTTATGGATT CTACCTGTCT CAACCAATTT GTGAGCACAG TGGCTGCCTC CCCTGAAAAC 3180

ATCTCTTTCC TCTCTGTTGC CCTCCTGAGT GACCAGCCAC TGCTGACCTC TGACCTCCTC 3240

TCCCTGCTGG CCCATGCAGC CCGGGTACTG TCTCCCAGCC ACTTGTTCTT CATCCAGGAA 3300

CTCCTGGCTG GCTCTGATGA ATCCTATCGA CCCCTGCGTA TCCTCCTAGG CCACCCAGAG 3360

AACTCCGTGC GTGCCCGTGC TTTTGGGCTC CTGGGATACT TGCTCCAACA CAGCATGGCT 3420

CTGCGTGGGG CACTGCAGAG CCAGGCTGGA CTGCTGAAAC TTCTGCTGCT GGGCCTTGGA 3480

GACCAGGACC CTGCTGTGCG GCGCAATGCC AGCTTTGCAG TGGGCAATGC AGCTTACCAA 3540

GCTGGTCCCC TGGGACCTGC CCTGGCAGCG GCAGTGCCCA ATATGGCCCA GCTACTTGAA 3600

GATGCTCAGG CTGGTATTCG ACGAAATGCT GCATCAGCTC TGGGCAACTT GGGGCCTGAG 3660

GGGCTGGGGG AGGAGCTACT CCAGTGCCAA GTACCCCAGC GGCTCCTAGA GATGGCATGT 3720

GGAGACCCTC AGCCAAATGT GAAGGAAGCC GCCCTCATTG CCCTCCGGAG CCTCCAACAG 3780

CAGCCATGTA TCCATGAGGT GCTGGTGTCC CTGGGTGCCA GTGAGAAGTT AGCCTTGCTC 3840

GCTCTGGGGA ATCAGTTACT GGTACAAAAC AGTTCCGGGC TTGCCTCTGC CAGACATTGC 3900

AAGAAACTCA TCCGCCTGCT AAAGCCACCT GACAGCACAT GA 3942

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         y++ e+iG+Gsf+ vykgr +k ++qvvA+k++ k ++ +k+l+nl++ei+i++ l+h+n

Q: 4     YHVLEMIGEGSFGRVYKGR-KKYSAQVVALKFIPKLGRtEKELRNLQREIEIMQGLRHPN  62

         8999***************.9*****************9*********************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv++ld++et+kev++v++y++ g+L ++l+++++L+e++v+++++ql+sal++Lhs++i

Q: 63    IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEEQVQAIAAQLVSALYYLHSHRI  121

         **********************.*************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesma.atlkGsplYmaPEvvk  178

         +hrD+kPqniLl+        k +++kl+dFg+ar++++++m  +++kG+plYm+PE+v+

Q: 122   LHRDMKPQNILLA--------KGGGIKLCDFGFARAMSTNTMVlTSIKGTPLYMSPELVE  173

         *************........89********************9****************

S: 179   eqqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdl  238

         e+ yd++aDlWS+G+ilyel+vG+pPf+++si++Lv+ i+k++v   ++p +is+++k++

Q: 174   ERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVNLIRKDPV---RWPPSISPCFKNF  230

         ********************************************...*************

S: 239   lqsLLqrdpkkRisfeelfahpfl  262

         lq+LL++dp++R+s+ +l++hpf+

Q: 231   LQGLLTKDPQQRLSWPDLLHHPFI  254

         **********************96

Domain Sequence
(FASTA)

YHVLEMIGEG SFGRVYKGRK KYSAQVVALK FIPKLGRTEK ELRNLQREIE IMQGLRHPNI 60

VHMLDSFETD KEVVVVTDYA EGELFQILED DGKLPEEQVQ AIAAQLVSAL YYLHSHRILH 120

RDMKPQNILL AKGGGIKLCD FGFARAMSTN TMVLTSIKGT PLYMSPELVE ERPYDHTADL 180

WSVGCILYEL AVGTPPFYTT SIFQLVNLIR KDPVRWPPSI SPCFKNFLQG LLTKDPQQRL 240

SWPDLLHHPF I 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013