EKS-CAP-00068

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00068

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	349.4	1.3E-104	104	388	285

Status

Unreviewed

Ensembl Protein

ENSCPOP00000002960

UniProt Accession

H0V0H1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000003272	ENSCPOP00000002960	ENSCPOT00000003315

Organism

Cavia porcellus

Functional Description

Protein Length

436

Protein Sequence
(FASTA)

MGQELCAKSR QPGCSCYHRS ERGEARSWPR GQPGAMEAAL KLSDLKEASR SMTSFHPQGE 60

LRAVSARKLR SKRPRSNSDP FQEGDPRQGF LWRKSLPFGA ASSYLHLEKL GEGSYATVYK 120

GVSRINGQLV ALKVISMNVE EGVPFTAIRE ASLLKGLKHA NIVLLHDIVH TKETLTFVFE 180

YMHTDLAQYM SQHPGGLHPH NVRLFMFQLL RGLAYIHQQH VLHRDLKPQN LLLSHQGELK 240

LADFGLARAK SIPSQTYSAE VVTLWYRPPD ALLGATEYSS ELDIWGAGCI FIEMFQGQPL 300

FPGVSNILEQ LERIWEVLGV PTEDTWPGVS KLPNYNPEWF LMPKPQRLQI TWNRLGEVPG 360

AEDLASRMLK GFPRARVSAR AALDHEYFQA LPPQLFQLLD EESLFTVSGV RLKPEMCDLL 420

ASYSKSHHPA QLTKCW 436

Nucleotide Sequence
(FASTA)

ATGGGTCAAG AGCTGTGTGC AAAGAGCCGA CAGCCTGGGT GCAGCTGCTA CCACCGTTCG 60

GAGAGAGGGG AGGCGCGCAG CTGGCCAAGG GGTCAGCCTG GGGCGATGGA GGCTGCGCTC 120

AAGCTATCAG ACCTAAAAGA AGCATCCCGT TCCATGACTT CATTCCACCC CCAGGGGGAA 180

CTCCGGGCTG TCAGTGCCAG GAAGCTGAGG AGTAAAAGGC CACGGAGTAA CAGTGATCCT 240

TTTCAGGAAG GGGATCCGAG GCAGGGTTTT CTGTGGAGGA AGAGCCTCCC GTTTGGGGCA 300

GCCTCATCCT ACTTGCACTT GGAGAAGCTG GGCGAAGGCT CTTACGCTAC AGTTTACAAG 360

GGTGTTAGCA GGATCAACGG GCAGCTGGTG GCTCTGAAGG TCATCAGCAT GAACGTGGAG 420

GAAGGAGTCC CATTCACGGC CATCCGGGAA GCTTCGCTCC TAAAGGGTTT GAAACATGCC 480

AATATTGTGC TCCTGCACGA CATAGTTCAC ACCAAAGAGA CACTGACCTT CGTTTTCGAG 540

TACATGCACA CAGACCTGGC CCAGTACATG TCCCAGCACC CGGGAGGGCT GCATCCACAC 600

AATGTCAGGC TTTTCATGTT TCAACTTTTG CGGGGCCTGG CGTACATCCA CCAGCAGCAT 660

GTTCTCCACA GGGACCTGAA ACCTCAGAAC TTGCTCCTCA GTCACCAGGG AGAGCTCAAG 720

CTGGCCGATT TCGGTCTTGC TCGGGCCAAG TCCATTCCCA GCCAGACATA CTCTGCAGAA 780

GTTGTGACCC TCTGGTACCG GCCCCCGGAT GCTTTGCTGG GAGCCACTGA ATATTCCTCT 840

GAGCTGGACA TATGGGGTGC AGGCTGCATC TTTATTGAAA TGTTCCAGGG TCAGCCTTTA 900

TTTCCTGGGG TTTCCAACAT CCTTGAACAG CTGGAGAGGA TCTGGGAGGT GTTAGGAGTC 960

CCTACTGAGG ATACCTGGCC TGGAGTTTCC AAGCTACCTA ACTACAACCC AGAATGGTTC 1020

CTGATGCCTA AGCCACAAAG ACTTCAGATC ACATGGAACA GGCTGGGCGA GGTTCCCGGG 1080

GCGGAGGACT TGGCCTCCCG GATGCTGAAA GGCTTTCCCC GAGCCCGCGT GTCCGCCCGA 1140

GCTGCGCTGG ACCACGAGTA TTTCCAGGCC CTGCCGCCCC AGCTGTTCCA GCTCCTGGAC 1200

GAAGAGTCTC TGTTTACAGT TTCAGGAGTG AGGCTGAAAC CAGAAATGTG TGACCTTCTG 1260

GCTTCCTACA GCAAGAGTCA CCACCCAGCC CAGCTTACCA AATGCTGGTG A 1311

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ +g++vAlK i ++ e egvp+ta+rE sllk lkh+ni

Q: 104   YLHLEKLGEGSYATVYKGVSRINGQLVALKVISMNVE-EGVPFTAIREASLLKGLKHANI  162

         66899*****************************999.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++v+ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 163   VLLHDIVH-TKETLTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHQQH  220

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlL+s++g+lklaDfGlara s p++ty+ evvTlwYr+P+ Llga+eYs+

Q: 221   VLHRDLKPQNLLLSHQGELKLADFGLARAKSIPSQTYSAEVVTLWYRPPDALLGATEYSS  280

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++DiW++gci+ e+++ +plf+g s+  +qleri+++lg p+e++wp+vsklp+y+ + f

Q: 281   ELDIWGAGCIFIEMFQGQPLFPGVSNiLEQLERIWEVLGVPTEDTWPGVSKLPNYNpEWF  340

         ***********************99967****************************8889

S: 239   pkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

            k+++l+ ++++l e   a dl +++l+  p+ R+sa++al+h+yf

Q: 341   LMPKPQRLQITWNRLGEVpgAEDLASRMLKGFPRARVSARAALDHEYF  388

         999999********99765589*************************9

Domain Sequence
(FASTA)

YLHLEKLGEG SYATVYKGVS RINGQLVALK VISMNVEEGV PFTAIREASL LKGLKHANIV 60

LLHDIVHTKE TLTFVFEYMH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHQQHVLH 120

RDLKPQNLLL SHQGELKLAD FGLARAKSIP SQTYSAEVVT LWYRPPDALL GATEYSSELD 180

IWGAGCIFIE MFQGQPLFPG VSNILEQLER IWEVLGVPTE DTWPGVSKLP NYNPEWFLMP 240

KPQRLQITWN RLGEVPGAED LASRMLKGFP RARVSARAAL DHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013