EKS-CAP-00262

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00262

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	421.9	1.1E-126	76	336	261

Status

Unreviewed

Ensembl Protein

ENSCPOP00000003203

UniProt Accession

H0V144;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000003543	ENSCPOP00000003203	ENSCPOT00000003587

Organism

Cavia porcellus

Functional Description

Protein Length

550

Protein Sequence
(FASTA)

YDTVPIQSSV VLCACPSPSM VRTQTESGTA PSVPSGGSRQ GPTMDGTTAE SRPSANNLQH 60

AAQPLPQPRK KRPEDFKFGK ILGEGSFSTV VLARELATSR EYAIKILEKR HIIKENKVPY 120

VTRERDVMSR LDHPFFVKLY FTFQDDEKLY FGLSYAKNGE LLKYIRKIGS FDETCTRFYT 180

AEIVSALEYL HGKGIIHRDL KPENILLNED MHIQITDFGT AKVLSPESKQ ARANSFVGTA 240

QYVSPELLTE KSACKSSDLW ALGCIIYQLV AGLPPFRAGN EYLIFQKIIK LEYDFPEKFF 300

PKARDLVEKL LVLDSTKRLG CEEMEGYEPL KAHSFFESIT WENLHQQTPP KLTAYLPAMS 360

EDDEDCYGNY DNLLSQFGCM QVSSSSSSHS LSAVDAGLPH RSGSNIEQYI HDLDTNSFEL 420

DLQFSEDEKR LLLEKQAGGN PWHQFVENNL ILKMGPVDKR KGLFARRRQL LLTEGPHLYY 480

VDPVNKVLKG EIPWSQELRP EAKNFKTFFV HTPNRTYYLM DPSGNAHKWC RKIQEVWRQR 540

YQSHPDAAVQ 550

Nucleotide Sequence
(FASTA)

TATGACACCG TTCCCATCCA GTCCAGCGTG GTGTTATGTG CCTGCCCATC CCCATCAATG 60

GTGAGGACAC AGACCGAGTC TGGCACAGCT CCCAGTGTTC CCAGTGGTGG CAGCAGGCAG 120

GGCCCCACCA TGGATGGCAC CACAGCCGAG TCCCGGCCAA GTGCCAACAA CTTGCAGCAT 180

GCTGCCCAGC CTCTACCACA GCCTCGAAAG AAACGGCCTG AAGACTTCAA GTTTGGAAAA 240

ATTCTTGGCG AGGGTTCTTT TTCGACAGTT GTCCTGGCCC GAGAACTAGC CACCTCTCGA 300

GAATATGCTA TTAAAATTCT GGAGAAACGT CATATTATAA AAGAAAACAA AGTCCCATAT 360

GTAACCAGAG AGCGAGATGT GATGTCACGC CTGGATCACC CTTTCTTCGT TAAGCTTTAC 420

TTCACTTTTC AGGATGATGA AAAGCTGTAC TTTGGCCTTA GCTATGCCAA AAATGGGGAA 480

TTACTTAAAT ACATCCGCAA AATTGGTTCA TTTGATGAGA CCTGCACTCG ATTTTACACA 540

GCTGAGATCG TGTCTGCTCT TGAGTACCTG CATGGCAAGG GCATCATTCA CAGGGACCTT 600

AAACCAGAAA ATATTTTGTT AAATGAAGAC ATGCACATCC AGATCACAGA TTTTGGAACA 660

GCAAAAGTGT TATCTCCAGA GAGTAAACAA GCCAGGGCCA ACTCATTTGT GGGAACAGCA 720

CAGTATGTTT CTCCAGAGCT GCTCACAGAG AAGTCAGCCT GTAAGAGTTC AGACCTTTGG 780

GCTCTTGGAT GTATAATATA CCAGCTTGTG GCAGGACTCC CACCATTCCG AGCTGGAAAT 840

GAATATCTTA TATTTCAGAA GATCATTAAG TTGGAATATG ACTTCCCAGA AAAATTCTTT 900

CCTAAGGCAA GAGACCTCGT GGAAAAACTC TTGGTTTTGG ATTCCACAAA GCGGTTAGGC 960

TGTGAAGAGA TGGAAGGGTA CGAACCTCTC AAGGCTCATT CATTCTTTGA ATCTATCACA 1020

TGGGAGAATC TGCACCAGCA GACACCCCCG AAGCTCACAG CTTACTTGCC AGCCATGTCA 1080

GAGGACGACG AGGACTGCTA TGGCAATTAT GATAATCTCC TGAGCCAGTT TGGCTGCATG 1140

CAAGTGTCGT CATCCTCCTC CTCCCATTCC CTGTCTGCAG TGGATGCTGG CCTGCCCCAT 1200

AGGTCAGGCA GCAACATAGA GCAGTACATC CATGATTTGG ACACTAACTC TTTTGAACTG 1260

GACTTACAGT TTTCTGAAGA TGAGAAGAGG TTATTATTGG AGAAGCAGGC CGGTGGAAAC 1320

CCTTGGCACC AGTTTGTAGA AAATAATTTA ATATTAAAAA TGGGTCCAGT GGATAAGCGA 1380

AAGGGTTTGT TTGCACGAAG ACGACAACTG TTGCTCACAG AAGGGCCACA TTTATATTAT 1440

GTTGATCCTG TCAACAAGGT CCTAAAAGGT GAAATTCCGT GGTCACAAGA ACTCCGACCA 1500

GAAGCCAAGA ATTTTAAAAC TTTCTTTGTC CACACGCCTA ACAGGACGTA TTACCTGATG 1560

GATCCAAGTG GGAATGCTCA CAAGTGGTGC AGAAAGATCC AGGAGGTTTG GAGGCAGCGA 1620

TACCAGAGCC ACCCAGATGC TGCTGTGCAG 1650

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++++eyaik+lekr+iike+kv+yvtre++v+++l +hp

Q: 76    FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL-DHP  134

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++sale+lh kg

Q: 135   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG  194

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+akvl+p++k+         ar++sfvGta+yvsP

Q: 195   IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ---------ARANSFVGTAQYVSP  245

         ******************************999999.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++ka+d

Q: 246   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARD  305

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv d ++rl++ee      +kah ff

Q: 306   LVEKLLVLDSTKRLGCEEmegyepLKAHSFF  336

         ******************99**********9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LATSREYAIK ILEKRHIIKE NKVPYVTRER DVMSRLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEIVS ALEYLHGKGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAKVLS PESKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYDF PEKFFPKARD LVEKLLVLDS 240

TKRLGCEEME GYEPLKAHSF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013