EKS-CAP-00151

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00151

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	517.5	9.1E-156	89	382	294

Status

Unreviewed

Ensembl Protein

ENSCPOP00000004034

UniProt Accession

H0V380;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38

Gene Synonyms/Alias

STK38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000004471	ENSCPOP00000004034	ENSCPOT00000004520

Organism

Cavia porcellus

Functional Description

Protein Length

465

Protein Sequence
(FASTA)

MAMTGSTPCS SMSNHTKERV TMTKVTLENF YSNLIAQHEE REMRQKKLEK VMEEEGLKDE 60

EKRLRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK 180

KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKGHVKLSD FGLCTGLKKA 240

HRTEFYRNLN HSLPSDFTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQTGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YKKVMNWKET LTFPPEVPIS ERAKDLILRF 360

CCEWEHRIGA PGVEEIKNNS FFEGVDWEHI RERPAVISIE IKSIDDTSNF DEFPESDILK 420

PTVATGNHPE TDYKNKDWVF INYTYKRFEG LTARGAIPSY MKAAK 465

Nucleotide Sequence
(FASTA)

ATGGCAATGA CAGGCTCCAC ACCGTGCTCC TCCATGAGTA ATCACACCAA GGAAAGAGTG 60

ACAATGACCA AAGTAACACT GGAGAATTTT TATAGCAACC TTATCGCTCA ACATGAAGAG 120

CGAGAAATGA GACAAAAGAA GTTAGAAAAA GTGATGGAAG AAGAAGGCCT AAAAGATGAA 180

GAGAAACGAC TCAGGAGATC AGCTCATGCT CGGAAGGAAA CAGAATTTCT CCGTTTGAAA 240

AGAACAAGAC TTGGACTGGA AGATTTTGAG TCCTTAAAAG TGATAGGCAG AGGTGCATTT 300

GGTGAGGTGC GGCTTGTTCA GAAGAAAGAT ACAGGGCATG TATATGCAAT GAAAATCCTC 360

CGCAAAGCAG ACATGCTTGA AAAGGAGCAG GTTGGCCACA TTCGTGCGGA GCGTGACATT 420

CTAGTGGAGG CAGACAGTTT GTGGGTTGTG AAAATGTTCT ATAGTTTTCA GGATAAGCTA 480

AACCTCTACC TAATCATGGA GTTCCTGCCT GGAGGGGACA TGATGACCCT GTTGATGAAA 540

AAAGACACTC TGACGGAAGA AGAGACTCAG TTTTACATAG CAGAGACAGT GTTAGCCATA 600

GACTCTATTC ACCAGCTCGG ATTCATCCAC AGAGACATCA AACCAGACAA CCTTCTGCTG 660

GACAGCAAGG GCCATGTGAA ACTTTCTGAC TTTGGCCTTT GCACAGGACT GAAGAAAGCA 720

CACAGGACAG AGTTCTATCG GAATCTGAAC CACAGCCTGC CCAGTGATTT CACTTTCCAA 780

AACATGAATT CCAAAAGGAA AGCAGAAACC TGGAAAAGAA ACAGACGTCA GCTAGCCTTC 840

TCCACAGTAG GCACTCCTGA CTACATTGCT CCCGAGGTGT TCATGCAGAC CGGGTACAAC 900

AAGCTCTGTG ATTGGTGGTC GCTTGGGGTG ATCATGTATG AGATGCTCAT CGGCTACCCA 960

CCTTTCTGTT CTGAGACCCC TCAAGAGACA TACAAGAAGG TGATGAACTG GAAAGAAACT 1020

CTGACTTTCC CTCCGGAAGT TCCCATCTCC GAGAGAGCCA AGGATCTCAT TCTGAGATTC 1080

TGCTGTGAAT GGGAACATAG AATTGGAGCC CCTGGAGTTG AGGAAATCAA AAATAATTCT 1140

TTTTTTGAAG GTGTTGACTG GGAACATATC AGAGAGAGAC CTGCGGTGAT ATCTATTGAA 1200

ATCAAAAGCA TTGATGATAC TTCAAACTTC GATGAGTTCC CCGAATCTGA TATTCTTAAG 1260

CCAACAGTGG CCACAGGCAA CCACCCTGAG ACCGACTACA AGAACAAAGA CTGGGTCTTC 1320

ATCAATTACA CATACAAGCG CTTTGAGGGC CTGACTGCAA GGGGGGCAAT ACCTTCCTAC 1380

ATGAAGGCAG CGAAA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d+kGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+ ++    ++++

Q: 209   IHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQ----NMNS  264

         *************************************************555....5555

S: 181   rkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPfla  236

         ++k    k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++

Q: 265   KRKaetwKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCS  324

         5544556*****************************************************

S: 237   etpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         etpqetykkv+nwketl+fp+ev++se+akdli r+++++e+r+g+ Gv+eik+++ff

Q: 325   ETPQETYKKVMNWKETLTFPPEVPISERAKDLILRFCCEWEHRIGAPGVEEIKNNSFF  382

         *********************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKADMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KLNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSKGHVKL SDFGLCTGLK KAHRTEFYRN LNHSLPSDFT FQNMNSKRKA 180

ETWKRNRRQL AFSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYKKVMNWK ETLTFPPEVP ISERAKDLIL RFCCEWEHRI GAPGVEEIKN NSFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013