EPS-CAP-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAP-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.3	2.5E-56	231	484	254

Status

Unreviewed

Ensembl Protein

ENSCPOP00000004136

UniProt Accession

H0V3H4;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000004589	ENSCPOP00000004136	ENSCPOT00000004638

Organism

Cavia porcellus

Functional Description

Protein Length

748

Protein Sequence
(FASTA)

MAGCGPEEKT YRRFLELFLG EFRGPCGGGD PEPEPEPECE PEPEPELVAT EAAEASVEEP 60

GEEAATLAAT EEVEQEPDSE PEEGAVEEAA AAAAEGEGEE EAAAAPGHSA VPPPPQPQLP 120

PLPPLPRPLS ERITREEVEG ESLDLCLQQL YKYNCPSFLA AALARATSDE VLQSDLSAHY 180

IPKETEGTEG TVEIETVKLA RSVFSKLHEI CCSWVKDFPL RRRPQLYYET SIHAIKNMRR 240

KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNL VRQEMFPHDP 300

AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV MLVRKGQAVE 360

LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI CGDADSASTV 420

LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA RDAGSSDNIT 480

VIVVFLRDMN KAVNVSEESD WTENSFQGGQ EDGGDDKENH GECKRPWPQH QCSAPADLGY 540

DGRVDSFTDS TSLSPGSHIN VLEDPGYLDL TQLEASKPHS AQFLPPVEMF GPGEPKKANL 600

NNELMMEEKS VQSSLHAWSG AGEFSASFNL GSTGQQIYRM ETLSPVCSGL ENKPSKSLAK 660

RIYRFYHPCY YYSKRWQKFY SFFSAQEPSH KIGINLTSVI RSGKKNRMVR SSVPWRENGW 720

KGYRDNTIKK TIKSNDIPCP DVFRSCKI 748

Nucleotide Sequence
(FASTA)

ATGGCCGGCT GTGGCCCTGA GGAGAAAACT TACCGGCGCT TCCTGGAGCT ATTCCTTGGC 60

GAGTTTCGCG GACCGTGCGG CGGCGGCGAC CCAGAGCCGG AACCCGAACC GGAGTGCGAG 120

CCCGAGCCCG AACCCGAACT GGTAGCCACT GAGGCGGCAG AGGCTTCGGT CGAGGAACCC 180

GGAGAGGAGG CAGCCACGCT CGCTGCCACG GAGGAGGTAG AGCAAGAGCC AGACTCGGAG 240

CCCGAAGAGG GGGCGGTGGA GGAGGCGGCG GCAGCGGCGG CCGAAGGCGA GGGGGAGGAG 300

GAAGCAGCGG CGGCCCCGGG GCACTCGGCC GTGCCACCAC CGCCGCAGCC CCAGCTGCCG 360

CCGCTGCCCC CACTCCCGCG ACCGCTGTCG GAGCGCATCA CCCGTGAGGA GGTGGAGGGC 420

GAGAGCCTGG ACCTGTGCCT GCAGCAGCTC TACAAATATA ACTGCCCTTC CTTTTTGGCT 480

GCAGCCTTGG CCAGAGCCAC CTCAGATGAA GTCCTCCAGA GTGACCTGTC TGCACATTAC 540

ATCCCAAAGG AGACCGAAGG CACAGAAGGA ACTGTGGAGA TTGAGACTGT GAAATTGGCC 600

CGGTCTGTCT TCAGCAAACT ACACGAGATT TGCTGCAGCT GGGTGAAAGA CTTCCCTCTC 660

CGCAGGAGAC CCCAGCTTTA TTATGAGACA TCAATCCATG CCATCAAAAA CATGCGCAGG 720

AAAATGGAGG ACAAACATGT CTGCATTCCC GACTTTAATA TGCTCTTCAA CCTAGAGGAC 780

CAAGAAGAAC AAGCTTACTT CGCAGTGTTT GATGGCCATG GGGGAGTGGA TGCTGCCATA 840

TATGCTTCCA TTCATTTACA TGTTAACTTA GTACGCCAGG AAATGTTCCC CCATGATCCT 900

GCTGAAGCTC TGTGCCGGGC CTTCCGGGTC ACTGACGAGC GCTTTGTGCA GAAGGCAGCT 960

AGGGAGAGCT TAAGATGTGG GACCACAGGA GTGGTGACTT TTATCAGAGG CAACATGCTA 1020

CACGTGGCCT GGGTGGGTGA TTCCCAGGTT ATGCTCGTGA GAAAGGGCCA AGCTGTTGAA 1080

CTAATGAAAC CACATAAACC AGATAGAGAG GATGAAAAGC AGCGAATTGA GGCCCTTGGA 1140

GGCTGTGTAG TCTGGTTTGG TGCCTGGAGG GTCAATGGAA GCCTGTCAGT CTCCAGAGCA 1200

ATAGGAGATG CTGAACATAA GCCATATATC TGTGGAGATG CAGATTCTGC CTCTACTGTC 1260

TTGGATGGGA CTGAAGACTA CCTCATTCTG GCCTGTGATG GCTTCTATGA TACTGTGAAC 1320

CCTGATGAGG CAGTGAAAGT TGTGTCTGAT CACTTGAAAG AAAACAATGG AGACAGCAGT 1380

ATGGTCGCCC ACAAATTAGT GGCATCGGCT CGCGATGCTG GGTCAAGTGA TAACATCACT 1440

GTTATTGTGG TATTCCTGAG GGACATGAAT AAAGCTGTAA ATGTTAGTGA GGAATCAGAT 1500

TGGACAGAGA ACTCTTTTCA AGGAGGGCAA GAAGATGGTG GGGATGATAA GGAGAATCAT 1560

GGAGAATGCA AACGCCCTTG GCCTCAGCAC CAGTGCTCAG CACCAGCCGA TCTAGGCTAT 1620

GATGGGCGTG TGGATTCATT CACTGATAGC ACCAGCCTCA GCCCAGGGTC CCATATCAAC 1680

GTGCTGGAAG ATCCAGGCTA CCTAGATCTC ACACAATTAG AAGCAAGCAA ACCTCACAGT 1740

GCTCAGTTTT TGCCACCAGT TGAAATGTTT GGTCCTGGTG AACCAAAGAA AGCCAATCTC 1800

AATAATGAGC TAATGATGGA GGAAAAATCA GTTCAATCAT CATTGCATGC ATGGAGTGGT 1860

GCTGGAGAGT TTTCTGCTTC TTTTAATTTG GGTTCCACAG GGCAGCAGAT ATACAGAATG 1920

GAGACTTTGT CTCCTGTCTG TTCTGGGTTA GAAAATAAAC CATCCAAATC TCTGGCGAAA 1980

AGAATTTATA GATTCTATCA TCCATGCTAT TACTACTCCA AGAGGTGGCA AAAGTTTTAT 2040

TCATTTTTCT CTGCTCAAGA GCCTTCCCAC AAAATAGGCA TTAACCTAAC TTCAGTTATT 2100

CGAAGTGGGA AGAAAAATAG GATGGTAAGA AGTTCTGTCC CATGGAGGGA AAATGGCTGG 2160

AAAGGGTACA GAGACAACAC AATAAAGAAA ACCATAAAGA GTAATGATAT TCCATGCCCA 2220

GATGTTTTCA GAAGTTGTAA AATA 2244

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 231   SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASIHLHVNL  290

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 291   VRQEM----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  344

         99955....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         vGdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 345   VGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  403

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+  +++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 404   AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKeNNGDSSMVA  463

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 464   HKLVASARDAGSSDNITVIVV  484

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNL 60

VRQEMFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>