EKS-CAP-00422

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00422

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	340.7	6.5E-102	1038	1301	264

Status

Unreviewed

Ensembl Protein

ENSCPOP00000004288

UniProt Accession

H0V3W6;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000004758	ENSCPOP00000017484	ENSCPOT00000023543
ENSCPOG00000004758	ENSCPOP00000004288	ENSCPOT00000004809

Organism

Cavia porcellus

Functional Description

Protein Length

1305

Protein Sequence
(FASTA)

YQSQPSTERH AESLLDICHD TNSPLADTMT ATKNQNIILQ SINSSEEFEQ DDDCSHSILV 60

SEKGERQDLP PRTEGVEIIM TFPKHVSHLQ EVSQEDVKKS NHTTSVHQEW TQAHSISLPN 120

EIEMMDFRTK VLTTRPLLLK KEASSKELCD VDFGFLLPKS CLEPSTSKSV TREEVPQFLK 180

EQQRKSEVEF STCAMKCSNR RIGFPQPPLS LLPIRSDVLT TLKSYKFPRE RERSISSFTS 240

FVPNFSVSPP PEALLVGQNL RTSGSSIWSR NMYSFWKGNH HRQHLEVEEN WRSKETERWD 300

KIEISCLDQR QCPFETFKEG NILRCRGEDI ECHGSDTRKA EENSQDLSSR KKQGSAPRKY 360

EEDSEIVCTF PSKPQEAQHS EIASVEDEEI RTDTIVSKSP LLHKSEATQS NILEEFTEFK 420

SLSNVISDGP TEKVLEGHTD METNMKISIA EGSKIDMNEK MPLVNITFPG DRTPKESTIA 480

KPTLQKRKST IQNNSFNILA QRENDKHKNI HRRKLNSKAK TSNRTSQNFT ISIQASIKPS 540

IHKTSIKTQV FPALELVDPK SQQSPKFQRR ISQIEKKQST SQTQKPKKES FPCICKNPGI 600

KAPCVPFSAQ PTEPRLHYLD LKYSDMFKEI NSTANGPGIY EMFGTPVYCH MREADRHENL 660

FYRELHSAPS GRCITNKCRS SHSERNSSSR SRLSQKRPNG KPPKPSATLK QKHKGLISKE 720

KGCKAAGRNL PDIENTNGIP EAGRQIKSSG NDLLSPRDGA QPMNLAQTLE KNPEQNQFLP 780

VSNLSIVEEI TMEESTNEGD ISNHQILTTS LRDLQELEEL HHQTPFVPLE NSWTMPTEKS 840

SIKHVQPEKQ STTSLHTLNA SQMLMNYLEF DNVLDKPKTL ADFSLQEKQE STSSQIYQYW 900

AHSLDPDSLT NKSIQFQTFG KTSKDTSSIS QEILDSLKNK ELTDELLGCL AAELLALDEK 960

DNNCCQIITN KRDSENLNHV LSRRGNTTKE LDREMTNVTI QQRYSNRFRI RDREKKFLTS 1020

NENMFSENSL KHEESVLWTK GEILGKGAYG TVYCGLTSQG QLIAVKQVTL DTSDKSATER 1080

EYRKLQEEVD LLKALKHVNI VTYLGTCLEE NIVSIFMEFV PGGSISSIIS RFGPLPEMVF 1140

CKYTKQILQG VAYLHENCVV HRDIKGNNVM LMPTGIIKLI DFGCAKRLAW AGLNGTHSDT 1200

LKSMHGTPYW MAPEVINESG YGRKSDIWSI GCTVFEMATG KPPLASMDRM AAMFYIGAHR 1260

GLMPPLPDHF SENAADFVRM CLTRDQHERP SAFQLLKHSF VTRNQ 1305

Nucleotide Sequence
(FASTA)

TATCAGTCAC AGCCTTCAAC AGAAAGACAT GCTGAATCAT TGCTTGACAT TTGTCATGAT 60

ACAAACTCTC CTCTAGCTGA TACAATGACA GCTACCAAAA ATCAAAACAT CATCTTGCAA 120

AGCATCAACA GCAGTGAGGA GTTTGAGCAA GATGATGACT GCAGTCATTC CATATTGGTT 180

AGTGAAAAAG GTGAAAGACA AGATTTGCCA CCCAGGACAG AAGGTGTTGA GATTATTATG 240

ACTTTTCCCA AACATGTCAG TCATCTCCAA GAAGTGAGCC AAGAAGATGT GAAAAAAAGC 300

AATCATACAA CTTCGGTGCA TCAGGAATGG ACACAAGCGC ATTCTATTTC TCTGCCAAAT 360

GAAATTGAGA TGATGGACTT CAGGACAAAG GTGCTGACCA CGAGGCCTTT ACTCCTTAAG 420

AAAGAAGCAA GTTCCAAGGA GCTCTGTGAT GTGGACTTTG GCTTTTTATT GCCCAAATCT 480

TGCTTAGAAC CAAGTACCTC CAAGTCGGTG ACCAGGGAAG AGGTTCCTCA ATTTCTGAAG 540

GAGCAGCAAA GAAAATCTGA AGTAGAGTTT TCTACATGTG CTATGAAATG CAGTAACCGA 600

AGAATTGGGT TCCCTCAGCC ACCACTGTCA CTCTTGCCCA TAAGATCTGA TGTCTTAACC 660

ACCCTTAAGA GTTACAAGTT TCCAAGAGAG AGAGAAAGAA GTATTTCAAG CTTCACATCC 720

TTTGTACCTA ACTTCTCAGT TAGTCCACCA CCGGAAGCCT TATTGGTGGG TCAGAATCTC 780

AGGACTTCTG GTAGCTCTAT TTGGTCAAGA AACATGTATT CTTTTTGGAA AGGTAATCAC 840

CATAGACAGC ACCTGGAGGT GGAGGAGAAT TGGAGGTCCA AGGAAACAGA AAGATGGGAC 900

AAAATTGAAA TCTCTTGCCT TGATCAAAGG CAGTGTCCTT TTGAGACTTT TAAGGAAGGC 960

AACATTCTTA GATGTCGGGG AGAGGATATT GAATGCCATG GCAGTGATAC GAGGAAGGCA 1020

GAAGAGAACT CCCAAGACCT TTCATCAAGA AAGAAACAAG GTTCAGCACC CAGAAAGTAT 1080

GAGGAAGATT CAGAAATTGT ATGTACTTTT CCAAGTAAGC CCCAAGAAGC CCAACATTCA 1140

GAAATAGCTT CAGTAGAGGA TGAAGAGATT AGAACGGATA CAATTGTTTC AAAAAGCCCT 1200

TTATTGCATA AAAGTGAAGC CACACAATCA AACATCTTAG AAGAGTTCAC TGAATTTAAA 1260

AGCTTGTCAA ATGTAATTTC TGATGGCCCC ACTGAAAAAG TCCTAGAAGG CCATACCGAT 1320

ATGGAGACAA ACATGAAAAT ATCCATAGCA GAAGGAAGCA AAATAGACAT GAATGAGAAG 1380

ATGCCTCTTG TTAACATCAC TTTCCCTGGA GACAGAACCC CCAAGGAATC AACTATAGCC 1440

AAACCAACCC TCCAAAAAAG AAAGAGCACC ATTCAGAACA ATAGTTTCAA CATACTTGCG 1500

CAACGTGAAA ATGACAAACA TAAGAATATC CATAGAAGAA AATTGAATTC AAAGGCCAAG 1560

ACAAGCAACA GGACATCTCA GAATTTCACA ATTTCCATTC AAGCTTCCAT TAAGCCAAGT 1620

ATACATAAAA CTAGCATAAA AACTCAAGTT TTCCCTGCTT TAGAGCTTGT TGATCCTAAG 1680

TCTCAGCAAT CACCTAAGTT TCAAAGGAGA ATATCACAAA TAGAAAAGAA GCAGTCAACT 1740

TCCCAAACTC AGAAACCTAA AAAGGAGTCA TTTCCTTGCA TCTGTAAAAA TCCAGGAATA 1800

AAAGCGCCTT GTGTTCCTTT CTCTGCTCAA CCAACTGAGC CAAGACTGCA TTACCTGGAT 1860

CTTAAGTATA GTGACATGTT CAAAGAAATT AATTCAACTG CTAATGGACC TGGAATATAT 1920

GAAATGTTTG GGACCCCTGT TTATTGTCAC ATGCGAGAGG CTGACCGACA TGAAAACTTG 1980

TTTTACCGTG AGTTACATTC AGCTCCATCA GGCAGATGTA TAACCAATAA ATGTCGCTCT 2040

TCCCACAGTG AGAGGAACAG CAGCAGCAGA TCAAGACTTT CTCAAAAAAG ACCAAATGGT 2100

AAACCTCCAA AGCCTTCAGC TACTCTTAAA CAAAAGCACA AAGGTTTAAT TTCTAAAGAA 2160

AAGGGCTGTA AGGCTGCAGG TAGAAACCTA CCAGACATTG AAAATACTAA TGGTATTCCA 2220

GAAGCAGGAC GGCAGATAAA ATCTTCAGGA AATGACCTTC TATCTCCTAG AGATGGAGCT 2280

CAGCCCATGA ACTTGGCCCA GACTCTGGAG AAGAACCCTG AACAGAACCA ATTCCTTCCT 2340

GTTTCAAATT TATCCATTGT TGAAGAAATC ACAATGGAAG AGTCTACCAA TGAAGGAGAC 2400

ATTTCTAACC ATCAAATACT CACCACAAGC CTTAGAGATC TGCAAGAACT TGAAGAGTTA 2460

CATCATCAGA CCCCATTTGT CCCTTTGGAA AACAGCTGGA CCATGCCCAC TGAGAAGAGT 2520

TCTATCAAGC ATGTACAGCC AGAAAAGCAG AGTACAACAT CTCTCCATAC GCTAAATGCC 2580

AGCCAAATGT TAATGAATTA TCTAGAATTT GATAATGTTT TAGATAAGCC TAAAACACTT 2640

GCAGATTTCT CTCTCCAAGA AAAGCAAGAA AGCACATCTT CCCAAATATA TCAATATTGG 2700

GCACATTCTT TGGATCCTGA TAGTTTAACA AATAAGTCAA TACAATTTCA AACATTTGGA 2760

AAAACTTCGA AGGATACAAG TTCAATTTCT CAAGAAATTC TAGATTCACT AAAGAATAAA 2820

GAATTGACAG ATGAACTATT AGGCTGTCTA GCTGCAGAAC TACTAGCTCT TGATGAAAAA 2880

GACAACAACT GTTGCCAAAT AATCACAAAT AAAAGAGATT CTGAAAACTT AAATCATGTC 2940

CTGAGTAGGA GAGGAAATAC CACAAAAGAA TTGGACAGAG AGATGACAAA TGTCACAATA 3000

CAGCAGAGGT ATAGTAATAG GTTCAGGATA CGTGACAGGG AGAAGAAATT TCTGACCTCA 3060

AATGAAAATA TGTTTTCTGA AAATAGTTTA AAGCATGAAG AATCTGTCCT GTGGACCAAG 3120

GGTGAGATCC TTGGGAAGGG AGCCTATGGC ACAGTATACT GTGGTCTCAC TAGCCAAGGA 3180

CAGTTAATAG CTGTAAAACA AGTAACTTTG GATACCTCTG ATAAATCGGC TACTGAAAGA 3240

GAATACCGGA AACTTCAGGA AGAAGTAGAT TTGCTCAAAG CACTGAAACA TGTCAACATT 3300

GTGACCTATT TGGGGACATG CTTGGAGGAG AACATTGTAA GCATTTTCAT GGAGTTTGTT 3360

CCTGGTGGCT CGATCTCTAG TATTATAAGC CGTTTTGGGC CATTGCCTGA GATGGTATTT 3420

TGTAAATATA CAAAACAAAT TCTACAAGGT GTTGCTTATC TCCATGAGAA TTGTGTGGTA 3480

CATCGAGATA TCAAGGGGAA TAATGTTATG CTAATGCCAA CTGGAATAAT AAAGCTGATT 3540

GATTTTGGCT GTGCCAAGCG TTTGGCCTGG GCAGGCTTAA ATGGTACTCA CAGTGACACG 3600

TTGAAGTCCA TGCATGGAAC TCCATACTGG ATGGCCCCAG AAGTCATCAA TGAGTCTGGC 3660

TATGGCAGAA AATCAGATAT ATGGAGCATT GGTTGCACTG TGTTTGAGAT GGCCACAGGG 3720

AAGCCTCCGC TGGCTTCTAT GGACAGGATG GCAGCCATGT TTTACATTGG AGCACACCGA 3780

GGGCTGATGC CTCCTTTGCC AGACCACTTC TCAGAAAATG CAGCAGACTT TGTGCGCATG 3840

TGCCTAACCA GGGACCAGCA TGAGAGACCT TCTGCTTTCC AGCTTCTGAA GCACTCTTTT 3900

GTGACAAGAA ATCAGTGA 3918

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekk.evkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++g+l+avK+v++++ +ks+++ e+++l+eE++llk+lk

Q: 1038  WTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVTLDTSDKSATErEYRKLQEEVDLLKALK  1096

         89*****************8.89***********9766655444****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv+y+G++ ee+ ++if+E+v+gGs+ss+++++g+l e+v++kytkqil+g+ayLHe

Q: 1097  HVNIVTYLGTCLEENIVSIFMEFVPGGSISSIISRFGPLPEMVFCKYTKQILQGVAYLHE  1156

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 1157  NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHsdtLKSMHGTPYWMAPEVI  1216

         **********************************999888777789**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++p+++se+

Q: 1217  NES--GYGRKSDIWSIGCTVFEMATGKPPLASM-DRMAAMFYIGAHRgLMPPLPDHFSEN  1273

         988..****************************.9**********9979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LLkh+f+

Q: 1274  AADFVRMCLTRDQHERPSAFQLLKHSFV  1301

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGQLIAVKQ VTLDTSDKSA TEREYRKLQE EVDLLKALKH 60

VNIVTYLGTC LEENIVSIFM EFVPGGSISS IISRFGPLPE MVFCKYTKQI LQGVAYLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGLNGTH SDTLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSIGCTVFEM ATGKPPLASM DRMAAMFYIG AHRGLMPPLP DHFSENAADF 240

VRMCLTRDQH ERPSAFQLLK HSFV 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013