EKS-CAP-00058

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00058

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	388.3	1.8E-116	165	446	282

Status

Unreviewed

Ensembl Protein

ENSCPOP00000004933

UniProt Accession

H0V5K0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK16

Gene Synonyms/Alias

CDK16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000005478	ENSCPOP00000004933	ENSCPOT00000005537

Organism

Cavia porcellus

Functional Description

Protein Length

496

Protein Sequence
(FASTA)

MDRMKKIKRQ LSMTLRGGRG LDKTNGAPEQ IGLDESGGGG GSDLGEAPTH IPPGEPRCGR 60

GPLSSAPEIV HEDLKMGSDG ESDQASATSS DEVQSPVRVR MRNHPPRKIS TEDINKRLSL 120

PADIRLPEGY LEKLTLNSPI FDKPLSRRLR RVSLSEIGFG KLETYIKLDK LGEGTYATVY 180

KGKSKLTDNL VALKEIRLEH EEGAPCTAIR EVSLLKDLKH ANIVTLHDII HTEKSLTLVF 240

EYLDKDLKQY LDDCGNVINM HNVKLFLFQL LRGLAYCHRQ KVLHRDLKPQ NLLINERGEL 300

KLADFGLARA KSIPTKTYSN EVVTLWYRPP DILLGSTDYS TQIDMWGVGC IFYEMATGRP 360

LFPGSTVEEQ LHFIFRILGT PTEETWPGIL SNEEFKTYNY PKYRAEALLS HAPRLDNDGT 420

DLLTKLLQFE GRNRISAEDA MKHPFFLSLG ERIHKLPDTT SIFALKEIQL QKEASLRSSS 480

MPDSGRPAFH VVDTEF 496

Nucleotide Sequence
(FASTA)

ATGGATCGGA TGAAGAAGAT CAAACGGCAG CTGTCAATGA CACTCCGAGG GGGCCGAGGC 60

CTAGACAAGA CCAATGGTGC CCCTGAGCAG ATAGGCCTGG ATGAAAGTGG CGGAGGTGGT 120

GGCAGTGACC TTGGAGAGGC TCCCACACAC ATACCTCCTG GTGAACCTCG CTGTGGACGT 180

GGCCCACTCA GCTCTGCACC AGAGATTGTA CATGAGGACT TGAAGATGGG GTCTGATGGG 240

GAGAGTGACC AGGCTTCAGC TACATCCTCG GATGAGGTGC AGTCTCCAGT GAGAGTGCGC 300

ATGCGCAACC ACCCCCCACG CAAGATCTCC ACTGAGGACA TCAACAAGCG CCTATCACTA 360

CCAGCCGACA TTCGGCTGCC TGAGGGCTAT CTTGAGAAGC TGACCCTCAA TAGCCCCATC 420

TTTGATAAGC CCCTTAGCCG CCGCCTCCGC CGTGTCAGCT TGTCCGAGAT TGGCTTTGGG 480

AAACTGGAGA CATATATCAA GCTGGACAAG CTGGGTGAGG GTACCTATGC CACCGTATAC 540

AAAGGCAAAA GCAAGCTCAC AGACAACCTT GTGGCACTCA AGGAGATCAG ACTGGAACAT 600

GAAGAGGGGG CACCCTGCAC GGCCATACGG GAAGTGTCCC TGCTCAAGGA CCTCAAACAT 660

GCCAACATCG TCACACTACA TGATATCATC CATACAGAGA AGTCCCTCAC CCTTGTCTTT 720

GAGTACCTGG ACAAGGACCT GAAGCAGTAC CTGGATGACT GTGGGAACGT CATCAACATG 780

CACAATGTGA AACTGTTCCT GTTCCAGCTG CTTCGTGGCC TGGCCTACTG CCACCGGCAG 840

AAGGTGCTAC ACCGAGACCT CAAGCCCCAG AACCTGCTCA TCAATGAGAG GGGAGAACTC 900

AAGCTGGCTG ACTTTGGCCT GGCCCGGGCC AAGTCAATCC CAACGAAGAC CTACTCCAAT 960

GAGGTGGTTA CACTGTGGTA CCGACCCCCT GACATCTTGC TTGGGTCCAC GGACTACTCT 1020

ACCCAAATTG ACATGTGGGG TGTGGGCTGC ATCTTCTACG AGATGGCCAC AGGTCGGCCC 1080

CTCTTCCCAG GCTCCACAGT GGAGGAACAG CTGCACTTCA TCTTTCGCAT CTTGGGAACC 1140

CCAACTGAGG AGACATGGCC AGGCATCTTG TCTAATGAAG AGTTCAAAAC ATACAACTAC 1200

CCCAAGTATC GAGCCGAGGC CCTTCTGAGC CATGCACCCC GACTTGATAA CGACGGGACT 1260

GACCTCCTTA CCAAGCTGCT GCAGTTTGAG GGCCGAAATC GGATCTCTGC AGAGGATGCC 1320

ATGAAACATC CATTCTTTCT CAGCCTGGGG GAACGGATCC ACAAACTTCC TGACACTACT 1380

TCCATATTTG CACTAAAAGA GATCCAGCTA CAAAAAGAGG CCAGCCTTCG GTCCTCATCA 1440

ATGCCTGACT CAGGCAGGCC AGCTTTCCAT GTGGTGGACA CCGAGTTCTA A 1491

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 165   YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  223

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ +  +++++vk +l+qll+glay+H++k

Q: 224   VTLHDIIH-TEKSLTLVFEYLDKDLKQYLDDCGN-VINMHNVKLFLFQLLRGLAYCHRQK  281

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 282   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  341

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 342   QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKtYNYP  401

         *******************************************************88***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l+++++dll+kll+++ ++Risa++a++h++f

Q: 402   KYRAEALLSHAPRLDNDGTDLLTKLLQFEGRNRISAEDAMKHPFF  446

         *******************************************98

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNVINMHNVK LFLFQLLRGL AYCHRQKVLH 120

RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR 240

AEALLSHAPR LDNDGTDLLT KLLQFEGRNR ISAEDAMKHP FF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013