EPS-CAP-00122

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAP-00122

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	264.8	8.8E-79	131	323	193

Status

Unreviewed

Ensembl Protein

ENSCPOP00000006493

UniProt Accession

H0V9J6;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF2

Gene Synonyms/Alias

PPEF2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000007202	ENSCPOP00000006493	ENSCPOT00000007274

Organism

Cavia porcellus

Functional Description

Protein Length

755

Protein Sequence
(FASTA)

HSRGPGTGHP LMATSHVLTA FKAAALIQRY RCYVARLEMR RRCTWSIFQS IEYAGQQDQG 60

QLHDFFSYLV DHFTPSSCHE GDILSRMLTE QSHPQDSELD TCSDYKAIEV PANYTGPRLS 120

FPLLPGHATA LVEAFRLKQQ QLHAHYVLHL LHETQRHLAQ LPNITRMSSC YSEELTVCGD 180

LHGQLDDLIF IFYKNGLPSP ERAYVFNGDF VDRGQDSVEI LMVLFAFMLV YPKKFHLNRG 240

NHEDHMVNLR YGFTKEVMRK YKIHGKKILR FQDVFCWLPL ATLVDEKVLI LHGGVSDRTD 300

LELLAKLDRH KIVSTMRWPT PREPKRPAEG PRLPSAAPCP PQRPIPWFLP QSRSLPSSLL 360

HAGPDSRTYR TGRSCSVPCS VPLDPRELSL RGRRSVNLEL DPGWQQAGSP SIQEQKEPSP 420

AAPEEALDDG ELQGPTQEEW QQVVDILWSD PMLQEGCKAN TVRGGGCYFG PDVTEQFLQK 480

YSLQLLIRSH ECKPEGYEFC HNRKVLTIFS ASNYYEVGSN RGAYVKLGPA LTPHIVQYQA 540

TKATHTLTLQ QRCPGSAERS SRQSALRALR EKLFAHSSDL LREFRKYDRS QTGVISWSDW 600

AAALEAVLHL GLPWWVLRPQ LVNGSVGSAL DYSAWLKDQA KDRPSPENIQ SSLLETLYRN 660

RSNLETIFRI IDSDHSGFLS LDELRQAWKL FSSYMGTVST EDCICDLAQS IDFNKDGRVD 720

INEFLEAFRL VEQSCSEGAT CDPVKDSSCS GPWAP 755

Nucleotide Sequence
(FASTA)

CATAGTAGGG GTCCAGGCAC AGGGCATCCC CTCATGGCGA CATCTCATGT GCTCACAGCC 60

TTCAAGGCGG CGGCCCTGAT CCAGAGGTAC CGGTGCTACG TGGCCCGGCT GGAAATGCGG 120

CGGCGCTGTA CCTGGAGCAT CTTTCAGTCC ATAGAGTATG CCGGGCAGCA GGACCAGGGC 180

CAGCTGCACG ACTTCTTCAG TTACCTTGTG GATCACTTCA CTCCCAGCAG CTGCCATGAG 240

GGGGACATCC TGAGCCGCAT GCTGACTGAG CAGAGCCATC CCCAGGATTC GGAGCTGGAT 300

ACCTGCAGTG ATTATAAAGC CATAGAGGTG CCTGCCAACT ACACAGGGCC ACGCCTGTCC 360

TTCCCGCTGC TTCCTGGCCA CGCCACTGCC CTGGTGGAAG CTTTTAGGCT TAAACAACAG 420

CAGCTGCATG CTCACTACGT CCTGCATCTC CTGCATGAGA CCCAGAGGCA CCTGGCGCAG 480

CTACCAAACA TCACCCGGAT GTCAAGCTGC TACAGTGAGG AGCTCACAGT GTGTGGAGAC 540

TTGCACGGCC AGCTGGACGA CTTAATATTC ATATTCTACA AGAATGGCCT CCCGTCGCCA 600

GAGCGGGCGT ACGTGTTCAA CGGTGACTTC GTGGACCGAG GCCAGGACTC AGTGGAGATC 660

CTGATGGTTC TATTCGCCTT CATGCTGGTT TACCCCAAAA AGTTCCATCT GAACCGAGGG 720

AACCATGAGG ACCACATGGT GAACCTGCGA TATGGTTTCA CCAAGGAAGT GATGCGTAAA 780

TACAAAATAC ATGGCAAGAA AATATTAAGA TTTCAGGATG TGTTCTGCTG GCTTCCGTTG 840

GCCACGCTAG TTGACGAGAA AGTCCTGATT CTTCATGGTG GAGTGTCGGA CAGGACTGAC 900

CTGGAGCTTT TGGCTAAATT AGACAGACAC AAGATTGTCT CCACTATGAG GTGGCCGACG 960

CCCAGGGAGC CCAAGAGGCC AGCAGAGGGG CCCCGCCTGC CCAGTGCTGC ACCGTGTCCC 1020

CCGCAGAGAC CCATACCCTG GTTCCTGCCC CAGAGCCGCT CACTCCCCTC CTCACTGCTC 1080

CATGCTGGCC CAGACAGCAG GACCTACAGG ACTGGCCGGT CCTGCAGCGT CCCCTGCAGT 1140

GTCCCCCTGG ACCCCCGGGA GCTGTCCCTG AGGGGACGGC GCTCTGTGAA TTTAGAACTG 1200

GACCCGGGCT GGCAGCAAGC GGGCTCCCCT AGCATCCAGG AGCAGAAGGA ACCCTCGCCT 1260

GCAGCCCCCG AGGAGGCCCT GGATGATGGA GAGCTGCAAG GGCCCACCCA GGAGGAGTGG 1320

CAACAGGTGG TGGACATCCT GTGGAGTGAC CCCATGCTGC AGGAGGGCTG CAAGGCCAAC 1380

ACTGTCCGTG GAGGGGGCTG TTACTTTGGG CCTGACGTGA CTGAGCAGTT TCTGCAGAAA 1440

TACAGCCTGC AGCTCCTGAT CCGATCCCAC GAGTGCAAGC CTGAAGGCTA TGAATTCTGC 1500

CACAACCGCA AGGTGCTGAC CATCTTTTCT GCCTCTAACT ACTACGAAGT TGGCAGTAAC 1560

AGAGGGGCCT ACGTCAAACT GGGGCCAGCC CTGACTCCAC ACATCGTGCA GTATCAAGCC 1620

ACCAAGGCCA CCCACACACT CACCTTGCAG CAAAGGTGCC CAGGGTCAGC AGAGCGGAGC 1680

AGTCGGCAGT CGGCGCTGAG AGCGCTGAGG GAGAAGCTGT TTGCCCACTC TTCAGACCTC 1740

CTGCGGGAAT TCAGGAAGTA TGACAGGAGC CAAACTGGTG TGATCAGCTG GAGCGACTGG 1800

GCAGCGGCTC TGGAGGCCGT GCTGCACCTG GGGCTGCCGT GGTGGGTGCT GAGGCCGCAG 1860

CTGGTGAATG GCAGTGTGGG CAGCGCTCTG GACTACTCGG CCTGGCTGAA GGACCAGGCC 1920

AAGGACCGGC CCAGCCCTGA GAACATCCAG TCGAGTTTGC TAGAAACTCT GTACCGGAAC 1980

AGATCCAACC TGGAGACCAT CTTTAGGATC ATAGACAGTG ATCACTCAGG GTTCCTTTCC 2040

CTGGATGAGC TCAGGCAGGC TTGGAAGCTG TTCAGCTCAT ACATGGGCAC TGTCAGCACC 2100

GAGGACTGCA TCTGCGACCT GGCCCAGAGC ATCGACTTCA ACAAGGACGG CCGCGTGGAC 2160

ATTAATGAGT TCCTGGAGGC CTTCCGCCTG GTGGAGCAGT CCTGCTCGGA GGGTGCCACC 2220

TGCGACCCCG TGAAGGACAG CAGCTGCAGC GGCCCCTGGG CACCCTGA 2268

Domain Profile

S: 4     llevfkkkr.ilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlll  62

         l+e+f+ k+ +lha+yvl++l+e+++ l qlpni+++s++ s+e+tv+GdlhG+lddl++

Q: 131   LVEAFRLKQqQLHAHYVLHLLHETQRHLAQLPNITRMSSCYSEELTVCGDLHGQLDDLIF  190

         899**965549*************************************************

S: 63    vlkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnar  122

         +++knGlPs +++yvfnGdfvdrG+ ++e+l+vl +++lv+P++ +lnrGnhed+++n+r

Q: 191   IFYKNGLPSPERAYVFNGDFVDRGQDSVEILMVLFAFMLVYPKKFHLNRGNHEDHMVNLR  250

         ************************************************************

S: 123   yGfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksver  182

         yGf+kev+ kyk +gk+ilr+ ++v+ wlPl+++vd++vl++hGG+s+ t+l+ll +++r

Q: 251   YGFTKEVMRKYKIHGKKILRF-QDVFCWLPLATLVDEKVLILHGGVSDRTDLELLAKLDR  309

         *******************97.689***********************************

S: 183   kkrksvllpPeess  196

         +k +s ++ P++ +

Q: 310   HKIVSTMRWPTPRE  323

         ********999765

Domain Sequence
(FASTA)

LVEAFRLKQQ QLHAHYVLHL LHETQRHLAQ LPNITRMSSC YSEELTVCGD LHGQLDDLIF 60

IFYKNGLPSP ERAYVFNGDF VDRGQDSVEI LMVLFAFMLV YPKKFHLNRG NHEDHMVNLR 120

YGFTKEVMRK YKIHGKKILR FQDVFCWLPL ATLVDEKVLI LHGGVSDRTD LELLAKLDRH 180

KIVSTMRWPT PRE 193

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Callithrix jacchus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0005506	; F:iron ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0050906	; P:detection of stimulus involved in sensory perception

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR012008	; Ser/Thr-Pase_EF-hand_contain.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 3.
PS50222	; EF_HAND_2; 3.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013