EKS-CAP-00233

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00233

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	466.6	2.1E-140	4	288	285

Status

Unreviewed

Ensembl Protein

ENSCPOP00000006742

UniProt Accession

H0VA73;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000007474	ENSCPOP00000006742	ENSCPOT00000007546

Organism

Cavia porcellus

Functional Description

Protein Length

575

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKNTGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFHHE 60

NMVTLIDVFK QKKKIHLVFE FVDHTVLDEL QHYCHGLESR RLRKYLFQIL RAVEYLHNNN 120

VIHRDIKPEN ILVSQSGIAK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

KRPVDIWALG CLIIEMATGS PHLPSSSDLD LLYKIVLKVG NLTPHLQNIF SKNPVFAGMI 240

LPQVQHPKNA RKKYPKLNGL LADIVDACLQ IDPGERISCT DLLHHEYFTR DGFAEKFLPE 300

LRAKLLQEAK VNSLIKSKEN YKENELLKDE RKTIFTNTLV STSVLGKDTE KEKKPKEIKV 360

TVFKVREGKG DTSELRKTEG EGRHGHQDTA ENVHALSQNT KPAVSNPPNP AIATASSSDV 420

KEEPHAEGYR IMPPINLTNT NLMAANPNSN LFHPNPRLTE RAKKRRTASQ SIRQVISNSR 480

QEDVGPTQSQ MEKSIFNERT SQSDQTASGY KRKLNFCRFD RKEFHFPELP FAVQSKDIKG 540

MEEVKQIKVL KRESKKTDSS KIPTLLNVDP NQEKQ 575

Nucleotide Sequence
(FASTA)

ATGGAGATGT ACGAAACTCT TGGAAAAGTG GGAGAGGGAA GTTATGGCAC TGTCATGAAG 60

TGTAAACATA AGAACACCGG GCAGATAGTG GCCATTAAGA TATTCTACGA GAAGCCAGAA 120

AAATCTGTCA ACAAAATTGC AACGAGAGAA ATAAAGTTTC TAAAGCAATT TCATCATGAA 180

AACATGGTTA CTCTGATTGA CGTTTTTAAA CAGAAAAAGA AAATTCACTT GGTGTTTGAA 240

TTTGTTGACC ACACAGTGTT AGATGAGTTA CAACACTATT GTCATGGACT AGAGAGTAGA 300

CGACTTAGAA AATACCTCTT CCAGATCCTT CGAGCAGTTG AGTATCTTCA CAATAATAAC 360

GTTATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTGT CCCAATCAGG AATCGCCAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACTCTA GCAGCTCCTG GTGACATTTA CACAGATTAT 480

GTGGCCACAC GCTGGTACAG AGCTCCAGAA CTAGTGTTAA AAGATACTTC TTACGGGAAA 540

AAGAGACCCG TGGATATCTG GGCCTTAGGC TGTCTGATCA TTGAGATGGC CACTGGAAGT 600

CCCCATCTTC CCAGCAGTTC TGATTTAGAT TTGCTCTATA AAATCGTTTT AAAAGTAGGC 660

AATTTGACAC CTCATCTGCA GAATATCTTT TCCAAGAATC CTGTATTTGC TGGAATGATC 720

CTTCCTCAAG TTCAACACCC CAAAAATGCA AGAAAAAAAT ATCCAAAGCT TAATGGATTA 780

TTGGCAGATA TAGTTGATGC TTGTTTACAA ATTGATCCTG GTGAGAGGAT ATCATGTACT 840

GATCTTTTGC ATCATGAGTA TTTTACTAGA GATGGATTTG CTGAAAAGTT CTTACCAGAA 900

TTAAGAGCTA AATTACTACA AGAAGCAAAA GTTAATTCAT TGATAAAGTC AAAAGAGAAT 960

TATAAAGAAA ATGAGCTATT AAAAGATGAA AGAAAAACCA TTTTTACCAA TACACTGGTA 1020

AGTACTTCAG TTTTGGGAAA GGACACAGAA AAAGAGAAAA AGCCCAAGGA GATCAAAGTC 1080

ACAGTTTTTA AAGTCAGAGA AGGAAAAGGA GATACCTCAG AACTGCGAAA GACAGAGGGT 1140

GAAGGTAGAC ACGGCCATCA GGACACAGCG GAAAATGTTC ATGCTTTGTC TCAAAACACA 1200

AAACCTGCAG TCTCCAACCC CCCAAACCCT GCCATTGCCA CCGCCAGCTC CAGTGATGTG 1260

AAGGAGGAGC CCCATGCTGA AGGCTACAGG ATCATGCCGC CCATCAATCT TACTAACACG 1320

AATTTGATGG CTGCAAATCC CAATTCGAAC CTCTTCCACC CCAATCCAAG GTTAACTGAA 1380

AGAGCGAAAA AGAGACGCAC TGCTTCGCAA TCTATTAGAC AAGTTATATC TAATAGCAGG 1440

CAAGAAGACG TAGGGCCAAC TCAGAGCCAG ATGGAGAAGA GTATCTTCAA TGAGCGCACA 1500

AGTCAAAGTG ACCAAACAGC AAGTGGCTAC AAAAGGAAGC TGAACTTTTG CAGATTTGAT 1560

AGGAAAGAAT TCCATTTCCC TGAGTTGCCT TTCGCGGTAC AGTCAAAGGA CATAAAAGGA 1620

ATGGAAGAAG TGAAACAGAT AAAAGTACTG AAGAGGGAGT CAAAGAAGAC AGATTCATCT 1680

AAAATACCGA CTCTACTTAA TGTGGATCCG AATCAAGAAA AGCAG 1725

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ k+v+kia+reik+lkq++hen+

Q: 4     YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFHHENM  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v l++vf++kkk++lvfe+vd+tvldel++y++G+e+++++k+l+qil+a+e++h+nn+i

Q: 63    VTLIDVFKQKKKIHLVFEFVDHTVLDELQHYCHGLESRRLRKYLFQILRAVEYLHNNNVI  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGk..  178

         hrdikpenil+s+sg+ klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk

Q: 123   HRDIKPENILVSQSGIAKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKkr  182

         *********************************************************756

S: 179   svdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklp  238

         +vd+wa+Gcl++e++tG+p +p++sd+d lyki+ ++G+l+p+ q+ifskn+vfaG+ lp

Q: 183   PVDIWALGCLIIEMATGSPHLPSSSDLDLLYKIVLKVGNLTPHLQNIFSKNPVFAGMILP  242

         8***********************************************************

S: 239   evedleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +v+++++++kkypkln +l+d++ +cl++dp er+sc++ll+heyf

Q: 243   QVQHPKNARKKYPKLNGLLADIVDACLQIDPGERISCTDLLHHEYF  288

         *********************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KNTGQIVAIK IFYEKPEKSV NKIATREIKF LKQFHHENMV 60

TLIDVFKQKK KIHLVFEFVD HTVLDELQHY CHGLESRRLR KYLFQILRAV EYLHNNNVIH 120

RDIKPENILV SQSGIAKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKKRP 180

VDIWALGCLI IEMATGSPHL PSSSDLDLLY KIVLKVGNLT PHLQNIFSKN PVFAGMILPQ 240

VQHPKNARKK YPKLNGLLAD IVDACLQIDP GERISCTDLL HHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013