EKS-CAP-00458

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00458

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	533.1	1.3E-160	160	417	258

Status

Unreviewed

Ensembl Protein

ENSCPOP00000006754

UniProt Accession

H0VA84;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000007486	ENSCPOP00000006754	ENSCPOT00000007559

Organism

Cavia porcellus

Functional Description

Protein Length

494

Protein Sequence
(FASTA)

KDYTMDYKES CPSVSIPSSD EHREKKKRFT VYKVLVSVGR SEWFVFRRYA EFDKLYNTLK 60

KQFPAMALKI PAKRIFGDNF DPDFIKQRRA GLNEFIQNLV RYPELYNHPD VRAFLQMDSP 120

KHQSDPSEDE DERNTQKLHS TSQNINLGPT GNPHAKPSDF DFLKVIGKGS FGKVLLAKRK 180

LDGKFYAVKV LQKKVVLNRK EQKHIMAERN VLLKNVKHPF LVGLHYSFQT SEKLYFVLDF 240

VNGGELFFHL QRERSFPEQR ARFYAAEIAS ALGYLHSIKI VYRDLKPENI LLDSVGHVVL 300

TDFGLCKEGI AISDTTTTFC GTPEYLAPEV IRKQPYDNTV DWWCLGAVLY EMLYGLPPFY 360

CRDVAEMYDN ILHKPLHLRP GVSLTAWSIL EELLEKDRQN RLGAKEDFLE IQNHPFFESL 420

SWTDLVQKRI PPPFNPNVAG PDDIRNFDTV FTEETVPYSV CVSSDYSIVN ASVLEADDAF 480

VGFSYAPPSE DLFL 494

Nucleotide Sequence
(FASTA)

AAAGATTATA CCATGGACTA CAAGGAAAGC TGCCCAAGTG TAAGCATTCC CAGCTCTGAT 60

GAACACAGAG AGAAAAAGAA AAGGTTTACT GTTTATAAAG TTCTAGTCTC TGTGGGCAGG 120

AGTGAGTGGT TTGTCTTCAG GAGATATGCA GAGTTTGACA AACTTTACAA CACTTTGAAG 180

AAACAGTTTC CTGCTATGGC TCTGAAGATT CCTGCCAAGA GAATATTTGG TGATAATTTT 240

GATCCAGATT TTATTAAACA AAGAAGAGCA GGACTGAATG AATTCATTCA GAACTTAGTT 300

AGATATCCAG AGCTTTACAA CCATCCAGAT GTTAGAGCAT TCCTTCAAAT GGACAGCCCA 360

AAACATCAGT CAGATCCATC TGAAGATGAG GATGAAAGAA ATACTCAGAA GCTACACTCT 420

ACCTCACAGA ACATCAACCT GGGACCAACT GGAAATCCTC ATGCTAAACC ATCTGACTTT 480

GACTTTTTAA AAGTTATTGG AAAAGGCAGC TTTGGCAAGG TTCTTCTTGC AAAACGAAAA 540

TTGGATGGAA AATTTTATGC TGTCAAAGTG TTACAGAAGA AAGTAGTTCT CAACAGGAAA 600

GAGCAAAAAC ATATTATGGC TGAACGTAAT GTTCTCTTGA AAAATGTGAA ACATCCATTT 660

TTGGTTGGAT TACATTATTC TTTCCAAACA AGTGAAAAAC TTTATTTTGT TCTGGATTTT 720

GTTAATGGAG GGGAGCTATT TTTTCACTTA CAAAGAGAAC GGTCTTTTCC TGAACAGAGA 780

GCGAGATTTT ATGCTGCTGA AATTGCCAGT GCATTGGGTT ATTTGCACTC CATCAAAATA 840

GTGTACAGAG ACTTGAAGCC AGAAAATATT CTTTTGGATT CAGTGGGACA TGTTGTCTTA 900

ACAGATTTTG GGCTTTGTAA AGAAGGAATT GCCATCTCTG ATACCACAAC AACATTTTGT 960

GGGACACCAG AGTACCTTGC TCCTGAAGTA ATCAGGAAAC AGCCCTATGA CAACACTGTG 1020

GATTGGTGGT GCCTTGGTGC TGTTCTGTAC GAAATGCTGT ATGGTTTGCC ACCCTTTTAC 1080

TGCCGAGATG TTGCTGAAAT GTATGATAAT ATTCTTCACA AGCCCCTACA TTTGAGGCCA 1140

GGAGTGAGCC TCACAGCATG GTCCATTCTG GAAGAACTCT TAGAAAAAGA CAGGCAAAAT 1200

CGACTTGGTG CCAAAGAAGA CTTTCTTGAA ATTCAGAATC ATCCTTTTTT TGAGTCACTC 1260

AGTTGGACTG ACCTTGTACA AAAGAGGATT CCGCCACCCT TTAATCCTAA TGTGGCTGGA 1320

CCAGATGATA TCAGGAACTT TGACACAGTA TTTACAGAGG AAACGGTTCC GTATTCTGTG 1380

TGTGTGTCTT CTGACTACTC TATCGTGAAT GCTAGTGTAC TGGAGGCAGA TGATGCATTC 1440

GTTGGTTTCT CTTATGCACC TCCTTCAGAA GACTTATTTT TA 1482

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk +l++ke+khimaernvllknvkhp

Q: 160   FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKVVLNRKEQKHIMAERNVLLKNVKHP  219

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlqrersf+e+rarfyaaeiasalgylhs++

Q: 220   FLVGLHYSFQTSEKLYFVLDFVNGGELFFHLQRERSFPEQRARFYAAEIASALGYLHSIK  279

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd+t

Q: 280   IVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT  339

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemydnil+kpl+l+pg+s++a+++leellekdr+

Q: 340   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLHLRPGVSLTAWSILEELLEKDRQ  399

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei+nh+ff

Q: 400   NRLGAKEDFLEIQNHPFF  417

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKVVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TSEKLYFVLD FVNGGELFFH LQRERSFPEQ RARFYAAEIA SALGYLHSIK 120

IVYRDLKPEN ILLDSVGHVV LTDFGLCKEG IAISDTTTTF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYD NILHKPLHLR PGVSLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQNHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013