EKS-CAP-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	334.5	4.6E-100	4	288	285

Status

Unreviewed

Ensembl Protein

ENSCPOP00000007716

UniProt Accession

H0VCP1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000008588	ENSCPOP00000007716	ENSCPOT00000008665

Organism

Cavia porcellus

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MDQYCILGRI GEGAHGIVFK AKHVETGEIV ALKKVALRRL EDGIPNQALR EIKALQEIED 60

SQFVVQLKAV FPHGMGFVLA FEFMLSDLAE VVRHAQKPLA PAQVKSYLQM LLKGVAFCHA 120

NNIVHRDLKP ANLLISASGQ LKIADFGLAR IFSPDGSRLY THQVATRWYR APELLYGARQ 180

YDQGVDLWAV GCIMGELLNG SPLFPGENDI EQLCCVLRIL GTPSPQVWPE ITELPDYNKI 240

SFKEQAPVPL QEVLPDASPQ ALDLLGRFLL YPPRQRIAAS QALLHQYFFT APLPAHPSEL 300

PVPQRPGGPV PKAHPGPPHI HDFHVDRPLE ESLLNPELIR PFIPEG 346

Nucleotide Sequence
(FASTA)

ATGGACCAGT ACTGCATCCT GGGCCGCATA GGGGAGGGCG CCCATGGCAT CGTCTTCAAG 60

GCTAAGCATG TGGAGACTGG TGAGATCGTT GCCCTCAAGA AGGTAGCCCT GCGGCGACTA 120

GAGGATGGCA TCCCCAACCA AGCCCTTCGG GAGATCAAGG CTCTGCAGGA GATTGAGGAC 180

AGTCAGTTTG TGGTGCAGCT GAAGGCTGTG TTCCCGCATG GCATGGGCTT TGTCCTGGCC 240

TTCGAGTTCA TGCTGTCAGA CCTGGCTGAA GTGGTTCGCC ATGCCCAGAA GCCACTGGCC 300

CCAGCCCAGG TTAAGAGCTA CCTGCAGATG CTGCTGAAGG GTGTGGCCTT CTGCCATGCC 360

AACAACATCG TGCATCGGGA CCTAAAACCT GCCAACCTGC TCATCAGCGC ATCAGGCCAG 420

CTCAAAATCG CTGACTTTGG CCTGGCCCGG ATCTTTTCTC CAGATGGCAG TCGCCTCTAC 480

ACACACCAGG TAGCCACCAG GTGGTACCGA GCCCCAGAGC TACTATACGG CGCCCGCCAG 540

TATGACCAAG GTGTGGACCT ATGGGCTGTG GGCTGCATCA TGGGGGAGCT GTTGAACGGC 600

TCCCCCCTCT TCCCAGGAGA GAACGACATT GAACAGCTTT GCTGTGTGCT GCGCATCTTG 660

GGCACCCCCA GCCCCCAAGT CTGGCCGGAG ATCACAGAGC TGCCGGACTA CAACAAGATC 720

TCCTTTAAGG AGCAGGCACC CGTGCCCCTG CAGGAGGTGC TGCCCGATGC CTCTCCTCAG 780

GCTTTGGATC TCCTGGGTCG CTTCCTCCTC TACCCGCCTC GCCAGCGCAT TGCAGCATCC 840

CAGGCCCTCC TGCATCAGTA CTTCTTCACG GCTCCCTTGC CTGCCCACCC ATCAGAGCTG 900

CCTGTTCCCC AGCGCCCAGG CGGGCCCGTC CCCAAGGCAC ATCCGGGGCC CCCCCACATC 960

CATGACTTCC ACGTGGACCG GCCTCTGGAG GAGTCGCTGT TAAACCCAGA GCTGATTCGG 1020

CCCTTCATCC CGGAGGGG 1038

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y  l +igeG++g v+kak+ etge+vAlKk++l + ++g+p +alrEi+ l+e+ + +

Q: 4     YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIeDSQF  63

         677899*************************************************67789

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +v+L+ v+  +   ++L fef+ +dL++++++ +k  l +++vks+l++ll+g+a++H+n

Q: 64    VVQLKAVFP-HGMGFVLAFEFMLSDLAEVVRHAQK-PLAPAQVKSYLQMLLKGVAFCHAN  121

         *********.99********************999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs + ++ yt++v T+wYraPelL+ga++Y

Q: 122   NIVHRDLKPANLLISASGQLKIADFGLARIFSPDGSRlYTHQVATRWYRAPELLYGARQY  181

         *******************************8766544**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgci+ ell+ +plf+g+++i+ql  ++++lgtps +vwpe+++lp+y+  s

Q: 182   DQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNkIS  241

         *********************************************************88*

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l+e++++++ +aldll ++l + p++Ri a++al h+yf

Q: 242   FKEQAPVPLQEVLPDASPQALDLLGRFLLYPPRQRIAASQALLHQYF  288

         **********************************************9

Domain Sequence
(FASTA)

YCILGRIGEG AHGIVFKAKH VETGEIVALK KVALRRLEDG IPNQALREIK ALQEIEDSQF 60

VVQLKAVFPH GMGFVLAFEF MLSDLAEVVR HAQKPLAPAQ VKSYLQMLLK GVAFCHANNI 120

VHRDLKPANL LISASGQLKI ADFGLARIFS PDGSRLYTHQ VATRWYRAPE LLYGARQYDQ 180

GVDLWAVGCI MGELLNGSPL FPGENDIEQL CCVLRILGTP SPQVWPEITE LPDYNKISFK 240

EQAPVPLQEV LPDASPQALD LLGRFLLYPP RQRIAASQAL LHQYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013