EKS-CAP-00298

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00298

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	356.6	7.4E-107	28	282	255

Status

Unreviewed

Ensembl Protein

ENSCPOP00000008320

UniProt Accession

H0VE85;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK5

Gene Synonyms/Alias

PLK5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000009268	ENSCPOP00000008320	ENSCPOT00000009353

Organism

Cavia porcellus

Functional Description

Protein Length

425

Protein Sequence
(FASTA)

MEPAARRQSR SRQLVAAFLR DPGSGRVYRR GKLIGQGAFS RCYKLTDLST SVVFALKVVP 60

RGGGGVGRLR PSGKVEREIA LHSGLRHRNI VALHGHFADR DHVYMVLEYC GRQSLAHVLK 120

ARQTLTEPEV RYYLRGVVSG LRYLHQQRIV HRDLKLSNFF LNSNMEVKIG DLGLAARVGP 180

GGRCHRVLCG TPNFLAPEVV SRHGHTCQSD IWALGCALYT ALTGSPPFPE TPLSELYQNI 240

RAARYPEPAH LSPSARQLIA RLLAPNPAER PTLDQLLQDA FFTQKGFTPE RLPPHSCHSP 300

PNFAVPPSLD GLLRKVGRLL LAECRLPRPF TPKENSGPGA ERLEPDPMEW TSGESERSWL 360

KESSWWEPRP MDPPDCSVPP DPEGSPRLEV EAAIRRFPQC LDSGPEDYSE VLGRGEPSSL 420

MAPAW 425

Nucleotide Sequence
(FASTA)

ATGGAGCCCG CGGCCAGGCG CCAGAGCCGG AGTCGCCAGC TGGTGGCCGC CTTCCTGCGC 60

GACCCCGGCT CGGGGCGCGT CTACCGGCGC GGGAAGCTCA TCGGCCAGGG CGCCTTCAGC 120

CGCTGCTACA AGCTCACCGA CCTGTCCACC AGCGTCGTGT TTGCGCTCAA GGTGGTGCCG 180

CGCGGCGGGG GCGGAGTGGG GCGTTTGCGC CCCTCGGGGA AGGTGGAGCG TGAGATCGCC 240

CTGCACAGCG GCCTCCGCCA CCGCAACATC GTGGCCCTCC ACGGTCACTT CGCCGACCGC 300

GACCACGTGT ACATGGTGCT GGAGTACTGC GGCCGCCAGT CGCTGGCCCA CGTGCTCAAA 360

GCCAGGCAGA CCTTGACGGA GCCCGAGGTG CGCTATTACC TGCGGGGCGT GGTCAGCGGC 420

CTGCGCTACC TGCACCAGCA GCGCATTGTG CACCGGGACC TGAAGCTCAG TAACTTCTTC 480

CTAAACAGCA ACATGGAGGT GAAGATCGGA GACCTGGGCC TGGCCGCCAG GGTAGGGCCA 540

GGGGGCCGCT GCCACAGGGT ACTCTGCGGA ACCCCAAACT TCCTGGCCCC GGAGGTGGTG 600

TCCCGGCACG GGCACACGTG CCAGTCTGAC ATCTGGGCCC TGGGCTGTGC CCTGTACACG 660

GCGCTCACCG GCAGCCCCCC TTTCCCGGAG ACGCCCCTCT CCGAGCTGTA CCAGAACATC 720

CGTGCCGCCC GCTACCCGGA GCCCGCCCAC CTGTCGCCCA GCGCGCGCCA GCTCATTGCC 780

CGCCTGCTGG CGCCCAACCC GGCCGAACGG CCCACCCTGG ACCAGCTGCT CCAGGACGCC 840

TTCTTCACCC AGAAGGGCTT CACCCCAGAG CGCCTGCCAC CCCATTCCTG CCACAGTCCC 900

CCCAACTTTG CAGTCCCCCC GTCTCTGGAT GGCCTCCTCC GGAAGGTGGG CCGGCTGCTG 960

CTCGCTGAAT GCCGGCTTCC CCGTCCCTTC ACCCCCAAAG AGAACTCAGG CCCAGGAGCA 1020

GAGAGGCTGG AACCAGACCC TATGGAGTGG ACCAGTGGGG AGAGTGAAAG GAGCTGGTTG 1080

AAGGAGTCAT CTTGGTGGGA ACCCAGGCCT ATGGACCCTC CAGATTGCTC TGTCCCCCCA 1140

GACCCTGAGG GGAGCCCACG GCTGGAAGTA GAGGCTGCCA TCAGGAGGTT TCCGCAGTGC 1200

CTGGACTCCG GCCCTGAGGA CTACTCGGAA GTGCTGGGTA GAGGTGAACC CTCCTCTCTG 1260

ATGGCACCAG CATGG 1275

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpks..llakekqrekvekeieihrslkh  58

         y+rgkl+G+G+f++cy+l+dl+t+ vfa+kvvp+    + + +   kve+ei++h+ l+h

Q: 28    YRRGKLIGQGAFSRCYKLTDLSTSVVFALKVVPRGggGVGRLRPSGKVEREIALHSGLRH  87

         99*******************************973368999999***************

S: 59    knivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhek  118

         +niv+l+ +f+d+++vy+vle+c r+sla++lk+r++ltepevryylr +vsgl+ylh++

Q: 88    RNIVALHGHFADRDHVYMVLEYCGRQSLAHVLKARQTLTEPEVRYYLRGVVSGLRYLHQQ  147

         ************************************************************

S: 119   rilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghsl  178

         ri+hrdlkl+n+fln+++evkigd+Gla+r+ + ++++++lcGtPn++aPev+s++gh++

Q: 148   RIVHRDLKLSNFFLNSNMEVKIGDLGLAARVGPGGRCHRVLCGTPNFLAPEVVSRHGHTC  207

         ************************************************************

S: 179   evdiWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkeP  238

         ++diW+lGc lyt l+G+PPf  + l+e+y++i+ a+y  P++ls++a++lia+ll+++P

Q: 208   QSDIWALGCALYTALTGSPPFPETPLSELYQNIRAARYPEPAHLSPSARQLIARLLAPNP  267

         ************************************************************

S: 239   eerpsleevlkdefl  253

         +erp+l+++l+d f+

Q: 268   AERPTLDQLLQDAFF  282

         *************98

Domain Sequence
(FASTA)

YRRGKLIGQG AFSRCYKLTD LSTSVVFALK VVPRGGGGVG RLRPSGKVER EIALHSGLRH 60

RNIVALHGHF ADRDHVYMVL EYCGRQSLAH VLKARQTLTE PEVRYYLRGV VSGLRYLHQQ 120

RIVHRDLKLS NFFLNSNMEV KIGDLGLAAR VGPGGRCHRV LCGTPNFLAP EVVSRHGHTC 180

QSDIWALGCA LYTALTGSPP FPETPLSELY QNIRAARYPE PAHLSPSARQ LIARLLAPNP 240

AERPTLDQLL QDAFF 255

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013