EKS-CAP-00328

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00328

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IKK	442.2	7.4E-133	9	293	285

Status

Unreviewed

Ensembl Protein

ENSCPOP00000009741

UniProt Accession

H0VHU6;

Protein Name

Protein Synonyms/Alias

Gene Name

TBK1

Gene Synonyms/Alias

TBK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000010846	ENSCPOP00000009741	ENSCPOT00000010945

Organism

Cavia porcellus

Functional Description

Protein Length

729

Protein Sequence
(FASTA)

MQSTPNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD VQMREFEVLK 60

KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVV 120

GGMNHLRENG IVHRDIKPGN IMRVIGEDGQ SVYKLTDFGA ARELEDDEQF VSLYGTEEYL 180

HPDMYERAVL RKDHQKKYGA TVDLWSIGVT FYHAATGSLP FRPFEGPRRN KEVMYKIITG 240

KPSGAISGVQ KAENGPIDWS GDMPISCSLS RGLQVLLTPV LANILEADQE KCWGFDQFFA 300

ETSDILHRMI IHVFSLQQMT HHKIYIHSYN TATVFHELVY KQTKIISSNQ ELIYEGRRLV 360

LEPGRLAQHF PKTTEENPIF VVGREPLTTI GLIYEKISLP KVHPRYDLDG DASMAKAVTG 420

VVCYACRIAS TLLLYQELMR KGIRWLIELA KEDYNETVHK KTEVVITLDF CIRNIEKTVK 480

VYEKLMKINL EAAELGDISD IHTKLLRLSS SQGTLETSLQ DVDSKLSPGG LLTDAWAHQE 540

GTHPKDRNVE KLQVLLNCIT EIYYQFKKDK AERRLAYNEE QIHKFDKQKL YYHATKAMTL 600

FSDECVKKYE TFLNKSEEWM RKMLHLRKQL LSLTNQCFDI EEEVSKYQDY TNELQETLPQ 660

KMFAASSGIK HTMTPIYPSS NTLVEMTLGM KKLKEEMEGV VKELAENNHI LERFGSLTMD 720

VGLRNVDGL 729

Nucleotide Sequence
(FASTA)

ATGCAGAGCA CTCCTAACCA TCTGTGGCTT TTATCTGATA TCTTAGGCCA AGGAGCTACT 60

GCAAATGTCT TTCGTGGAAG ACATAAGAAA ACTGGTGATT TATTTGCTAT CAAAGTGTTT 120

AATAACATAA GTTTCCTTCG TCCAGTGGAT GTTCAAATGA GAGAATTTGA AGTGTTAAAA 180

AAACTGAATC ACAAAAATAT TGTCAAGTTA TTTGCTATTG AAGAAGAGAC AACAACCAGA 240

CATAAAGTAC TCATTATGGA ATTTTGTCCA TGTGGGAGTT TATACACAGT TTTAGAAGAG 300

CCATCTAATG CCTATGGACT ACCAGAATCA GAATTTTTAA TTGTTTTACG TGATGTGGTG 360

GGTGGAATGA ATCACCTCCG AGAGAATGGC ATAGTGCACC GTGATATCAA GCCAGGAAAC 420

ATCATGCGTG TCATCGGGGA GGATGGGCAG TCGGTATACA AACTCACAGA TTTTGGTGCA 480

GCCAGAGAAT TAGAAGATGA TGAACAATTT GTTTCTCTTT ATGGCACAGA GGAATATTTG 540

CATCCTGATA TGTATGAGAG AGCAGTACTA AGAAAAGATC ATCAGAAGAA GTATGGAGCA 600

ACAGTTGATC TTTGGAGCAT TGGAGTAACA TTTTATCATG CAGCTACCGG ATCACTGCCA 660

TTTAGACCGT TTGAAGGGCC ACGTCGCAAC AAAGAAGTAA TGTATAAAAT AATTACTGGA 720

AAGCCTTCTG GTGCAATATC TGGAGTACAG AAGGCAGAAA ATGGACCAAT TGATTGGAGC 780

GGAGACATGC CTATTTCTTG TAGTCTTTCT CGGGGTCTTC AAGTCCTTCT TACCCCTGTT 840

CTTGCAAACA TTCTTGAAGC AGATCAGGAA AAGTGTTGGG GTTTTGATCA ATTTTTTGCA 900

GAAACTAGTG ATATTCTTCA CCGAATGATA ATTCATGTTT TTTCGCTACA ACAAATGACA 960

CACCATAAGA TTTATATTCA TAGCTATAAT ACTGCTACTG TATTTCATGA ATTGGTGTAT 1020

AAACAAACCA AAATTATCTC TTCAAATCAA GAATTGATCT ATGAAGGACG ACGCTTAGTC 1080

CTGGAACCTG GAAGACTGGC ACAGCATTTT CCTAAAACGA CAGAGGAAAA TCCTATCTTT 1140

GTAGTAGGCC GGGAACCCCT GACTACCATA GGATTAATAT ATGAGAAAAT TTCCCTTCCG 1200

AAAGTACATC CACGTTATGA TTTAGATGGG GATGCTAGCA TGGCTAAGGC AGTAACAGGA 1260

GTTGTGTGCT ATGCCTGTAG AATTGCCAGT ACCTTGCTCC TTTATCAGGA ATTAATGCGA 1320

AAGGGGATAC GATGGTTGAT TGAATTAGCT AAAGAGGATT ACAATGAAAC TGTTCATAAA 1380

AAGACAGAAG TTGTGATCAC ATTGGATTTC TGCATCAGAA ACATTGAAAA AACTGTAAAA 1440

GTATATGAAA AGTTGATGAA GATCAACCTA GAAGCAGCAG AATTAGGTGA TATTTCAGAT 1500

ATACACACCA AACTGTTGAG ACTTTCCAGT TCTCAGGGAA CATTAGAAAC CAGTCTGCAG 1560

GACGTTGACA GCAAATTATC TCCAGGTGGA TTATTGACAG ATGCATGGGC ACATCAAGAA 1620

GGAACTCATC CAAAAGACAG AAATGTAGAA AAACTACAAG TCCTGTTAAA TTGCATCACA 1680

GAGATTTACT ATCAGTTCAA AAAGGACAAA GCAGAACGTA GATTGGCTTA TAATGAAGAA 1740

CAAATCCACA AATTCGATAA GCAAAAATTG TATTACCATG CAACAAAAGC GATGACACTT 1800

TTCTCAGATG AATGTGTTAA AAAGTATGAA ACATTTTTGA ATAAGTCAGA AGAATGGATG 1860

AGAAAGATGC TTCATCTTAG GAAACAGTTG TTATCTCTAA CTAACCAGTG TTTTGATATT 1920

GAAGAAGAAG TATCAAAGTA TCAAGACTAT ACTAATGAGT TACAGGAAAC TCTGCCTCAG 1980

AAAATGTTTG CAGCTTCCAG TGGAATCAAA CATACCATGA CCCCAATTTA CCCAAGTTCT 2040

AACACATTAG TGGAAATGAC ACTAGGTATG AAGAAATTAA AGGAAGAGAT GGAAGGAGTG 2100

GTTAAAGAAC TTGCTGAAAA TAATCATATT CTAGAAAGGT TTGGGTCTTT AACCATGGAT 2160

GTTGGCCTAC GGAATGTCGA CGGTCTT 2187

Domain Profile

S: 1     WelkelLGeGafgnvikarnkktgekiavkvikeesslrprevqvrelevlrklnhkniv  60

         W l+++LG+Ga++nv+++r+kktg+ +a+kv++++s+lrp++vq+re+evl+klnhkniv

Q: 9     WLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIV  68

         999*********************************************************

S: 61    klvdveeelnlasarlkvlvleyCsgGdlrkvLeepenayGLkesevlvvLsdvvaglry  120

         kl+++eee   +++r+kvl++e+C +G+l++vLeep+nayGL+ese+l+vL+dvv g+++

Q: 69    KLFAIEEE---TTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNH  125

         ********...*************************************************

S: 121   LrenkivhRDlkPenivllkgedgksiykltDlGaareldddekvvslvGteeYlaPely  180

         Lren+ivhRD+kP+ni++++gedg+s+ykltD+Gaarel+dde++vsl+GteeYl+P++y

Q: 126   LRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMY  185

         ************************************************************

S: 181   e........qkkytatvDlWsiGvllyeaitGslPflpfegprr....lykkitkkpaka  228

         e        qkky+atvDlWsiGv++y+a+tGslPf+pfegprr    +yk+it kp++a

Q: 186   EravlrkdhQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRnkevMYKIITGKPSGA  245

         ************************************************************

S: 229   iagteka.ngevefssslPlsaslssglqeklekllanllevdeekrw  275

         i+g++ka ng++++s ++P+s+sls+glq  l+++lan+le+d+ek+w

Q: 246   ISGVQKAeNGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCW  293

         *******9***************************************9

Domain Sequence
(FASTA)

WLLSDILGQG ATANVFRGRH KKTGDLFAIK VFNNISFLRP VDVQMREFEV LKKLNHKNIV 60

KLFAIEEETT TRHKVLIMEF CPCGSLYTVL EEPSNAYGLP ESEFLIVLRD VVGGMNHLRE 120

NGIVHRDIKP GNIMRVIGED GQSVYKLTDF GAARELEDDE QFVSLYGTEE YLHPDMYERA 180

VLRKDHQKKY GATVDLWSIG VTFYHAATGS LPFRPFEGPR RNKEVMYKII TGKPSGAISG 240

VQKAENGPID WSGDMPISCS LSRGLQVLLT PVLANILEAD QEKCW 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>