EKS-CAP-00091

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00091

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	412.5	1.3E-123	1926	2256	331

Status

Unreviewed

Ensembl Protein

ENSCPOP00000009885

UniProt Accession

H0VI73;

Protein Name

Protein Synonyms/Alias

Gene Name

ATM

Gene Synonyms/Alias

ATM;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000010997	ENSCPOP00000009885	ENSCPOT00000011098

Organism

Cavia porcellus

Functional Description

Protein Length

2298

Protein Sequence
(FASTA)

SLMQCAGESV SLFKNKTDEE SRIGSLRSMM YLCSRCLCNC TKQNPNKITS GFFLRLLTSK 60

LMNDIADICK SLASFIKKPF DYEKVKAEDD PNENLKDVND SSSNLFHDCP SSSASDTNDP 120

GENQSTIGAM NPLAEEYLSK QDLLLLDMLK FLCMCVTTSQ TKSVSFRAAD IRRRLLMLID 180

SLDFNKSLHL HMYLMLLKEL PGEQYPLPVE DVVELLKPLS IVCSLYRRDQ DVCKTILKHV 240

LHVVTNLGQG NTDSEHAREA QGQFLTVIGA FWHLTKEKKC TFSVRMAIVK CLKTLLEADP 300

YSKWAILNVK GEGYPINEIF PQFLTDDNHQ VCMLTAESIN RLFQDMKQDS SMFPKALPLK 360

LQQTAFENAH LKAQEGMKGV FHDAENPELL DETYNRKSVF LMTIAIILHC SPVCEKQALF 420

TLCKSVKENG LDPHLVKKVL EKVSETFGYT RLEDFMASHL DYLVSEWLNL QDTAYSLSSF 480

PFVLLNYTNV EDFYRSYYKV LIPHLVIRSY FDEVKSIANQ IQEDWKKLLI ACFPKILVNI 540

LPYFAYEDTG DSWMAQKRET ATKVYDMLKS ENLLGRQIDH LFTSNLPEIV VELLMTLHEP 600

GNSDAGQSTD LCNFSGDLDP IPNPPCFPSH VIKATFAYIS NCHKTKHKSI LDILSKSPDS 660

YQKILLAICE QAAETNNVYK KHRILKIYHL FVSLLLKDIK SGLGGAWAFV LRDVIYTLIH 720

YINQRTSHLM GVSLRSFSLC CDLLNLVCQT AVIHCKDALE NHLHVIVGTL IPLVNTQVEV 780

QKQVLDLLKY LVIDNKDNEN LYLTIKLLDP FPDHVVFKDL RITQQKIKYS RGSFSLLEEI 840

NHFLSVSVYD ALPLTRLEGL KDLRRQLEQH KDQMINLMRA SQDNPQDGIV LKLVVSLLHL 900

SKKAINHTGE KEVLEAVASC LGEVGPIDFS TIAVQHSKDT SYTKTVELFE DKELQWTLIM 960

LNCLNNTLIE DGVKVRSAAV TCLKNILATK TGHKFWEIYK MTTDPMLTYL QPFRTSRKKF 1020

LEVPRLDKES PLEDLDDTSL WIPQSENHDI WIKTLTCAIL DSKGTKSEIL QLLKPMCEVK 1080

TDFCQTVLPY LIHDILLQDA NESWRNLLST HIQGFFTSCF RHLSQASRST TPANLDSESE 1140

LFSQCCLDKK SQRTMLAVVD YMRRQKRPLS GTVFEDAFWL DLNYLEVAKV AQSCAAHFTA 1200

LLYAEIYADK KTIDDQEKRS LTFEEGSQST SISSLSEKSK EETGISLQDL LLEIYRSIGE 1260

PDSLYGCGGG KMLQPLTRLR TYEHEAMWGK ALVTYDLETA ISSSTRQAGI IQALQNLGLC 1320

HILSVYLKGL DHESKEQCAE LHYQAAWRNM QWDQCGSVNK EIEGSSYHES LYNALHSLRD 1380

KEFSTFFECL RYARVKEVEE LCKGSLESVY SLYPALSRLQ AIGELENIGE LFSRSVTDTQ 1440

LSEMYIKWHK HSQLLKDSDF SFQEPIMALR TVILEILMEK KMESSQIECF KDILTKHLVE 1500

FSILARTFNN TQLPERAMFQ IKQYNSAVCG VSEWQLEEAQ VFWAKKEQSL ALSILKQMIK 1560

KLDACTQSNS NLKLIYTECL RICGTWLAET CLENPAVIMQ TYLEKAVQIA RSYDGESNDE 1620

LRNGKMRAFL SLARFSDTQY QRIENYMKSS EFENKQALLK RAKEEVGLLR EHKIQTNRYT 1680

VKVQRELELD ECALRALRED RERFLCKAVE NYINCLLSGE EHDMWVFRLC SLWLENSGVF 1740

EVNAMMKKDG MKISSYKFLP LMYQLAARMG TKTMGDEGFH EVLNNLISRI TMDHPHHALF 1800

IILALANANK DEFLTKPEAA RRSRITKNVP KQNSQLDEDR TEAANRIIHT IRSKRPQMVK 1860

NVEALCDAYI ILANLDASQW KTQRKGINIP ADQPINKLKN LEDVVVPTME IKVDPTGEYG 1920

NLVTIQSFKT EFRLAGGLNL PKIIDCLGSD GKERRQLVKG RDDLRQDAVM QQVFQMCNTL 1980

LQRNTETRKR KLTICTYKVV PLSQRSGVLE WCTGTVPIGE FLVNNEDGAH KRYRPMDFSA 2040

FQCQKKMMEV QKKSFEEKYE TFMDICQNFQ PVFRYFCMEK FLDPAVWFEK RLAYTRSVAT 2100

SSIVGYILGL GDRHVQNILI NEQSAELVHI DLGVAFEQGK ILPTPETVPF RLTRDIVDGM 2160

GITGVEGVFR RCCEKTMEVM RNSQETLLTI VEVLLYDPLF DWTMNPLKAL YLQQRPEDEN 2220

ELHSTPNADD QQCKRNLSDT DQSFNKVAER VLMRLQEKLK GVEEGTVLSV GGQVNLLIQQ 2280

AMDPKNLSRL FPGWKPWV 2298

Nucleotide Sequence
(FASTA)

TCTTTAATGC AGTGTGCAGG AGAAAGTGTC TCTCTGTTTA AAAATAAGAC AGATGAAGAA 60

TCTAGAATTG GGTCATTGAG AAGTATGATG TATTTGTGTT CAAGGTGCTT GTGTAACTGT 120

ACCAAGCAAA ATCCAAACAA GATTACATCT GGCTTTTTCC TACGATTGTT AACATCAAAG 180

CTGATGAATG ATATTGCAGA TATTTGTAAA AGTTTAGCAT CCTTTATCAA AAAGCCGTTT 240

GACTATGAGA AAGTAAAAGC GGAAGATGAT CCTAATGAAA ATCTAAAAGA TGTAAATGAT 300

TCATCTTCAA ACCTGTTTCA TGATTGCCCT TCTAGCAGTG CAAGTGATAC AAATGATCCT 360

GGAGAGAACC AAAGTACCAT TGGTGCTATG AATCCGTTAG CAGAAGAGTA TCTGTCAAAG 420

CAAGATCTGC TTCTTTTAGA CATGCTCAAG TTTTTGTGTA TGTGTGTAAC TACATCTCAG 480

ACTAAGTCTG TGTCATTTAG AGCTGCTGAT ATTCGAAGAA GATTATTAAT GCTAATTGAT 540

TCACTAGATT TTAATAAATC CCTCCACTTA CACATGTACT TAATGCTTTT AAAGGAGCTA 600

CCTGGAGAGC AGTATCCTTT GCCAGTAGAA GATGTTGTTG AACTTCTGAA ACCACTATCC 660

ATTGTGTGTT CTTTGTATCG CCGTGACCAA GATGTTTGTA AAACAATTTT AAAGCATGTC 720

CTTCATGTAG TGACAAACCT AGGTCAAGGT AATACAGATT CAGAGCATGC AAGGGAGGCT 780

CAAGGACAGT TCCTTACAGT GATTGGGGCA TTTTGGCATC TAACAAAAGA GAAGAAATGC 840

ACATTCTCTG TAAGAATGGC AATAGTAAAA TGCCTTAAAA CTCTACTTGA GGCTGATCCT 900

TACTCAAAAT GGGCTATTCT TAATGTAAAG GGAGAAGGCT ATCCTATAAA TGAAATATTT 960

CCACAATTTC TTACTGATGA TAATCACCAA GTATGCATGT TAACTGCAGA ATCAATTAAT 1020

AGATTGTTCC AGGATATGAA ACAAGATTCT TCCATGTTTC CGAAAGCGCT TCCTTTGAAG 1080

CTTCAACAAA CAGCTTTTGA AAATGCACAC TTGAAAGCTC AGGAAGGAAT GAAAGGAGTG 1140

TTTCATGATG CTGAGAATCC TGAACTTTTG GATGAGACTT ACAATAGAAA ATCTGTTTTC 1200

TTGATGACCA TAGCTATTAT TTTACACTGT AGCCCTGTCT GTGAAAAACA AGCATTATTT 1260

ACCCTATGCA AGTCTGTGAA AGAGAATGGA TTAGATCCAC ACCTTGTGAA AAAGGTTTTA 1320

GAGAAAGTTT CTGAAACTTT TGGCTATACA CGTTTGGAAG ACTTCATGGC TTCTCACTTA 1380

GATTATCTGG TTTCAGAGTG GCTAAATCTT CAAGATACTG CATACAGTTT ATCTTCTTTT 1440

CCTTTTGTTT TACTAAACTA CACAAATGTT GAGGATTTCT ATAGGTCTTA TTATAAGGTT 1500

TTAATTCCAC ATCTGGTGAT TAGAAGTTAT TTTGATGAGG TGAAGTCCAT TGCTAATCAG 1560

ATTCAAGAGG ATTGGAAAAA ACTTCTAATA GCCTGCTTCC CAAAGATTCT TGTAAATATT 1620

CTTCCTTATT TTGCATATGA GGATACTGGA GACAGTTGGA TGGCACAGAA AAGAGAGACT 1680

GCTACCAAGG TCTACGATAT GCTTAAAAGT GAAAACCTAT TAGGAAGACA GATTGATCAT 1740

TTGTTCACTA GTAATTTACC AGAGATTGTG GTGGAGTTAC TGATGACATT ACATGAACCA 1800

GGAAATTCTG ATGCTGGCCA GAGCACTGAC CTCTGTAACT TTTCAGGGGA TTTGGATCCT 1860

ATTCCTAATC CACCTTGTTT TCCATCACAT GTTATTAAAG CAACATTTGC CTATATCAGC 1920

AATTGTCATA AAACCAAGCA TAAAAGCATT TTAGATATTC TTTCCAAAAG CCCTGATTCC 1980

TATCAGAAAA TTCTTTTAGC CATTTGTGAG CAAGCAGCTG AGACCAATAA TGTTTATAAG 2040

AAGCACAGAA TTCTTAAAAT ATATCATCTG TTTGTCAGCT TATTACTAAA GGATATAAAA 2100

AGTGGCTTGG GAGGAGCTTG GGCCTTTGTT CTTCGAGATG TTATTTATAC CTTAATTCAC 2160

TATATTAACC AAAGGACTTC CCATCTCATG GGTGTGTCAT TACGAAGCTT CTCCCTTTGT 2220

TGTGACCTGT TAAATCTGGT TTGCCAGACA GCAGTGATTC ATTGCAAGGA TGCTTTAGAA 2280

AACCATCTTC ATGTTATTGT TGGTACACTT ATACCCCTTG TAAACACTCA GGTGGAGGTT 2340

CAAAAGCAGG TATTGGACTT ACTGAAATAC TTAGTGATAG ATAACAAGGA TAATGAAAAC 2400

CTCTATCTCA CAATTAAGCT TTTAGATCCT TTTCCTGACC ATGTTGTTTT TAAGGATTTA 2460

CGAATTACTC AGCAGAAAAT CAAATACAGC AGAGGATCCT TTTCACTCTT GGAGGAAATT 2520

AACCATTTTC TCTCAGTTAG TGTGTATGAT GCACTTCCAC TGACAAGGCT TGAAGGCTTG 2580

AAGGATCTTC GAAGACAACT GGAACAACAT AAAGATCAGA TGATAAATCT TATGAGAGCA 2640

TCTCAAGATA ACCCACAAGA TGGCATTGTG TTAAAGCTAG TTGTCAGCTT GTTGCATTTA 2700

TCAAAGAAGG CAATAAACCA CACTGGTGAA AAAGAAGTTT TAGAAGCTGT TGCAAGCTGC 2760

TTGGGAGAAG TGGGTCCTAT AGATTTCTCT ACCATAGCTG TACAACATAG TAAAGATACT 2820

TCTTATACCA AGACTGTAGA GTTATTTGAA GATAAAGAAC TTCAGTGGAC CTTAATAATG 2880

CTGAACTGTC TGAATAACAC ATTAATAGAA GATGGTGTCA AAGTTCGATC AGCTGCTGTT 2940

ACCTGTTTGA AAAATATTTT AGCCACAAAG ACTGGACATA AATTTTGGGA GATTTATAAG 3000

ATGACAACTG ATCCCATGCT GACCTATCTA CAGCCTTTTA GAACATCAAG AAAAAAGTTT 3060

TTAGAAGTTC CCAGACTTGA CAAAGAAAGC CCTTTAGAAG ACTTGGATGA TACTAGTCTG 3120

TGGATTCCTC AAAGTGAAAA TCATGATATT TGGATAAAGA CTCTGACTTG TGCTATTTTG 3180

GACAGTAAAG GCACAAAAAG TGAAATTCTT CAGTTATTAA AGCCAATGTG TGAAGTGAAA 3240

ACTGACTTTT GTCAGACTGT CCTTCCATAC TTGATTCATG ATATTTTACT CCAAGATGCA 3300

AATGAATCAT GGAGGAATCT GCTTTCTACC CATATTCAAG GATTTTTTAC TAGCTGTTTC 3360

AGACACTTGT CGCAAGCAAG CCGATCCACA ACCCCTGCAA ATCTGGATTC AGAGTCAGAG 3420

CTCTTTTCCC AATGCTGCTT GGATAAAAAA TCACAAAGAA CAATGCTTGC TGTTGTAGAC 3480

TATATGAGGA GACAGAAGAG ACCTTTGTCA GGAACAGTTT TTGAAGATGC CTTCTGGCTG 3540

GATTTGAATT ATCTAGAAGT GGCCAAGGTA GCTCAGTCTT GTGCTGCACA CTTTACAGCA 3600

TTGCTCTACG CAGAAATCTA TGCAGATAAG AAAACCATAG ATGATCAAGA GAAAAGAAGT 3660

CTTACATTTG AAGAAGGAAG CCAAAGTACA AGTATTTCTA GTTTGAGTGA AAAAAGTAAA 3720

GAAGAAACGG GAATAAGTCT GCAGGATCTT CTCTTAGAAA TCTACAGAAG TATCGGAGAA 3780

CCAGATAGTC TGTATGGCTG TGGTGGAGGG AAAATGTTAC AGCCTCTTAC TAGACTTCGA 3840

ACATATGAAC ATGAAGCAAT GTGGGGGAAA GCCTTAGTAA CATATGACCT TGAGACAGCG 3900

ATTTCCTCAT CAACCCGCCA GGCAGGAATA ATTCAGGCTT TGCAGAATCT GGGACTCTGT 3960

CATATTCTGT CCGTCTATTT AAAGGGATTA GATCATGAAA GTAAAGAGCA GTGTGCTGAG 4020

CTTCATTACC AGGCTGCGTG GAGGAATATG CAGTGGGACC AGTGCGGTTC TGTCAATAAA 4080

GAAATAGAAG GATCCAGTTA CCATGAATCA TTGTACAATG CTCTGCACTC TCTAAGAGAC 4140

AAAGAATTCT CCACATTTTT TGAGTGTCTC AGATATGCCA GAGTCAAAGA AGTAGAAGAA 4200

TTATGTAAGG GCAGCTTGGA ATCTGTGTAT TCGTTATACC CGGCACTTAG TAGATTGCAG 4260

GCCATTGGAG AACTGGAAAA CATTGGGGAG CTTTTCTCCA GGTCAGTCAC AGATACACAG 4320

CTCTCTGAAA TGTATATTAA GTGGCACAAA CACTCCCAGC TTCTCAAGGA CAGTGATTTT 4380

AGTTTTCAGG AGCCCATCAT GGCTCTGCGT ACAGTCATTT TGGAGATCCT AATGGAAAAG 4440

AAGATGGAGA GCTCCCAGAT AGAATGTTTT AAGGACATTC TTACCAAACA CCTTGTAGAA 4500

TTCTCTATTC TGGCACGAAC TTTCAACAAC ACTCAGCTCC CTGAAAGAGC AATGTTTCAA 4560

ATTAAACAGT ATAATTCAGC TGTTTGTGGA GTCTCTGAAT GGCAGCTGGA AGAAGCCCAA 4620

GTATTCTGGG CCAAAAAAGA ACAGAGTCTT GCCCTGAGTA TTCTCAAACA AATGATCAAG 4680

AAGTTGGATG CCTGTACACA GAGTAATTCA AACCTTAAAC TTATATACAC AGAATGTCTG 4740

AGGATTTGTG GCACCTGGTT AGCAGAAACA TGCTTGGAAA ATCCTGCAGT CATCATGCAG 4800

ACCTATTTAG AAAAGGCAGT GCAGATTGCT CGAAGTTATG ATGGAGAAAG CAATGATGAG 4860

CTCAGAAATG GAAAAATGAG AGCTTTTCTT TCATTAGCAA GGTTCTCTGA TACTCAGTAC 4920

CAGAGAATTG AAAACTACAT GAAATCATCA GAATTTGAAA ACAAGCAAGC TCTCTTGAAA 4980

CGGGCCAAAG AGGAAGTCGG CCTCCTAAGG GAACATAAAA TTCAGACCAA CAGATACACG 5040

GTAAAGGTTC AGAGAGAGCT GGAGCTCGAT GAGTGTGCCC TCCGTGCATT GAGAGAGGAT 5100

CGTGAACGCT TCCTATGTAA AGCAGTTGAA AATTACATTA ACTGTTTATT AAGTGGAGAA 5160

GAGCATGATA TGTGGGTGTT TCGACTTTGT TCCCTATGGC TTGAAAATTC TGGAGTTTTT 5220

GAAGTTAATG CCATGATGAA GAAAGACGGA ATGAAGATTT CGTCATACAA GTTTTTACCT 5280

CTTATGTACC AACTAGCTGC TCGAATGGGG ACTAAAACGA TGGGAGATGA AGGATTTCAT 5340

GAAGTACTCA ATAATCTCAT CTCTAGAATT ACAATGGATC ACCCCCATCA TGCTTTATTT 5400

ATTATATTGG CTTTAGCAAA TGCAAACAAA GATGAATTTT TAACCAAACC AGAGGCAGCA 5460

AGAAGGAGTA GAATAACTAA AAATGTGCCA AAACAGAACT CTCAGCTTGA TGAGGATCGA 5520

ACAGAAGCTG CAAACAGAAT AATACATACC ATCAGAAGTA AGAGACCTCA GATGGTCAAG 5580

AATGTGGAGG CACTTTGTGA TGCTTATATT ATATTAGCAA ACTTAGATGC CAGTCAGTGG 5640

AAGACGCAGA GAAAAGGCAT CAACATTCCA GCAGATCAAC CAATTAATAA ACTTAAGAAT 5700

TTAGAAGATG TTGTTGTTCC TACTATGGAA ATTAAGGTGG ATCCCACAGG TGAATATGGA 5760

AATCTGGTGA CAATCCAGTC ATTTAAAACA GAATTTCGTT TAGCAGGAGG CTTAAATTTA 5820

CCAAAAATAA TAGATTGCTT AGGTTCTGAT GGCAAGGAAA GGAGACAGCT TGTCAAGGGC 5880

CGTGATGACT TGAGACAGGA TGCTGTCATG CAGCAGGTGT TCCAGATGTG TAATACACTA 5940

CTGCAGAGAA ATACGGAAAC TAGGAAGAGG AAATTGACTA TCTGCACATA CAAGGTGGTC 6000

CCTCTCTCTC AGCGAAGTGG TGTTCTTGAG TGGTGCACAG GAACTGTCCC TATTGGTGAA 6060

TTTCTGGTTA ACAATGAAGA TGGTGCTCAT AAAAGATATA GGCCAATGGA TTTCAGTGCC 6120

TTTCAATGCC AAAAGAAAAT GATGGAAGTA CAGAAGAAGT CCTTTGAAGA GAAATATGAA 6180

ACGTTCATGG ATATTTGCCA AAATTTTCAA CCAGTTTTCC GTTACTTCTG CATGGAAAAA 6240

TTCCTGGACC CTGCTGTTTG GTTCGAGAAA CGGTTGGCTT ATACTCGTAG CGTGGCCACG 6300

TCTTCTATTG TTGGTTACAT CCTTGGCCTT GGTGATAGGC ATGTACAGAA CATCTTGATA 6360

AATGAACAGT CAGCAGAACT TGTCCATATA GATTTAGGGG TTGCTTTTGA ACAGGGTAAA 6420

ATCCTTCCCA CTCCTGAAAC AGTTCCTTTT AGACTCACCA GAGATATTGT GGATGGCATG 6480

GGCATCACTG GTGTTGAAGG TGTCTTCAGA AGATGCTGTG AGAAAACCAT GGAAGTTATG 6540

AGAAATTCTC AAGAAACTCT GTTAACCATT GTAGAGGTGC TCTTGTATGA CCCTCTCTTT 6600

GACTGGACCA TGAATCCTTT GAAAGCTTTG TATTTACAGC AGAGGCCTGA AGATGAAAAT 6660

GAGTTGCACT CGACTCCTAA TGCAGATGAC CAGCAATGCA AACGAAATCT CAGTGATACT 6720

GACCAGAGTT TCAACAAAGT CGCTGAACGT GTCTTGATGA GATTGCAAGA AAAACTGAAA 6780

GGAGTGGAGG AAGGCACCGT GCTCAGTGTG GGTGGACAAG TGAATCTGCT CATCCAGCAG 6840

GCCATGGACC CCAAAAATCT CAGCCGGCTC TTCCCAGGGT GGAAGCCTTG GGTG 6894

Domain Profile

S: 2     agfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdk  61

         ++f+ +  +   ++ pk +  +Gsdgke+++Lvkg++Dlrqd++++q+f+++NtlL++++

Q: 1926  QSFKTEFRLAGGLNLPKIIDCLGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNT  1985

         666666666677788999******************************************

S: 62    etsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdls  121

         et++rkL+i+tykVvpls+rsg++ew+++tv+++e+l   v++++++++   +yr+ d+s

Q: 1986  ETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFL---VNNEDGAHK---RYRPMDFS  2039

         *************************************...799*****9...********

S: 122   tvqarkpklkhlkls....levfkevlenlvpkdllkklllekfpspeewfelrkaytrs  177

         ++q++k++++++k+s    +e f+++++n++p  +++++++ekf++p++wfe+r aytrs

Q: 2040  AFQCQKKMMEVQKKSfeekYETFMDICQNFQP--VFRYFCMEKFLDPAVWFEKRLAYTRS  2097

         ********************************..9*************************

S: 178   lAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrni  237

         +A++s+vgyiLgLgdrh++n+li+++++e+vhid+gvafe++k+ l++pe+vPFRLTr+i

Q: 2098  VATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLTRDI  2156

         ********************************************.***************

S: 238   vnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk......kkktsk  291

         v+++g+tgveGvfr++ce++++v+r+s+e+llti+ev+lydpl+dw++      + ++++

Q: 2157  VDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMnplkalYLQQRP  2216

         ******************************************************9*****

S: 292   eteeelaekakaealkikkllskvekaenavatrdlllle  331

         e+e+el+++ +a+++++k++ls+ ++++n+va+r+l++l+

Q: 2217  EDENELHSTPNADDQQCKRNLSDTDQSFNKVAERVLMRLQ  2256

         ***********************************99987

Domain Sequence
(FASTA)

QSFKTEFRLA GGLNLPKIID CLGSDGKERR QLVKGRDDLR QDAVMQQVFQ MCNTLLQRNT 60

ETRKRKLTIC TYKVVPLSQR SGVLEWCTGT VPIGEFLVNN EDGAHKRYRP MDFSAFQCQK 120

KMMEVQKKSF EEKYETFMDI CQNFQPVFRY FCMEKFLDPA VWFEKRLAYT RSVATSSIVG 180

YILGLGDRHV QNILINEQSA ELVHIDLGVA FEQGKILPTP ETVPFRLTRD IVDGMGITGV 240

EGVFRRCCEK TMEVMRNSQE TLLTIVEVLL YDPLFDWTMN PLKALYLQQR PEDENELHST 300

PNADDQQCKR NLSDTDQSFN KVAERVLMRL Q 331

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0016572	; P:histone phosphorylation
GO:0090399	; P:replicative senescence
GO:0010212	; P:response to ionizing radiation
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013