EKS-CAP-00089

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00089

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.2	3.0E-133	2153	2477	325

Status

Unreviewed

Ensembl Protein

ENSCPOP00000010469

UniProt Accession

H0VJM9;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000011641	ENSCPOP00000010469	ENSCPOT00000011753

Organism

Cavia porcellus

Functional Description

Protein Length

2545

Protein Sequence
(FASTA)

MLGTGPAAAT TAAATSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFEVK RALEWLGADR NEGRRHAAVL VLRELAISVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPQQSNAL VGLLGYSSHQ GLMGFGASPS PAKPTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPGIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPGL ATLPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSIHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR SVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEVPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR STAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD VLICRIVKGY TLADEEEDPL IYQHRMLRSG QGDALASGPV ETGPMKKLHV 1260

STINLQKAWG AARRVSKDDW LEWLRRLSLE LLKDSSSPSL RSCWALAQAY NPMARDLFNA 1320

AFVSCWSELN EDQQDELIRS IELALTSQDI AEVTQTLLNL AEFMEHSDKG PLPLRDDNGI 1380

VLLGERAAKC RAYAKALHYK ELEFQKGPTP AILESLISIN NKLQQPEAAA GVLEYAMKHF 1440

GELEIQATWY EKLHEWEDAL VAYDKKMDTN KDDPELMLGR MRCLEALGEW GQLHQQCCEK 1500

WTLVNDETQA KMARMAAAAA WGLGQWDSME EYTCMIPRDT HDGAFYRAVL ALHQDLFSLA 1560

QQCIDKARDL LDAELTAMAG ESYSRAYGAM VSCHMLSELE EVIQYKLVPE RREIIRQIWW 1620

ERLQGCQRIV EDWQKILMVR SLVVNPHEDM RTWLKYASLC GKSGRLALAH KTLVLLLGVD 1680

PSRQLDHPLP TVHPQVTYAY MKNMWKSARK IDAFQHMQHF VQTVQQQAQH AVATEDQQHK 1740

QELHKLMARC FLKLGEWQLN LQGINESTIP KVLQYYSAAT EHDRSWYKAW HAWAVMNFEA 1800

VLHYKHQNQA RDEKKKLRHA SGANITSATT AATTAATATA TASTEGSNSE SEAESTENSP 1860

TPSPLQKKVT EDLSKTLLLY TVPAVQGFFR SISLSRGNNL QDTLRVLTLW FDYGHWPDVN 1920

EALVEGVKAI QIDTWLQVIP QLIARIDTPR PLVGRLIHQL LTDIGRYHPQ ALIYPLTVAS 1980

KSTTTARHNA ANKILKNMCE HSNTLVQQAM MVSEELIRVA ILWHEMWHEG LEEASRLYFG 2040

ERNVKGMFEV LEPLHAMMER GPQTLKETSF NQAYGRDLME AQEWCRKYMK SGNVKDLTQA 2100

WDLYYHVFRR ISKQLPQLTS LELQYVSPKL LMCRDLELAV PGTYDPNQPI IRIQSIAPSL 2160

QVITSKQRPR KLTLMGSNGH EFVFLLKGHE DLRQDERVMQ LFGLVNTLLA NDPTSLRKNL 2220

SIQRYAVIPL STNSGLIGWV PHCDTLHALI RDYREKKKIL LNIEHRIMLR MAPDYDHLTL 2280

MQKVEVFEHA VNNTAGDDLA KLLWLKSPSS EVWFDRRTNY TRSLAVMSMV GYILGLGDRH 2340

PSNLMLDRLS GKILHIDFGD CFEVAMTREK FPEKIPFRLT RMLTNAMEVT GLDGNYRITC 2400

HTVMEVLREH KDSVMAVLEA FVYDPLLNWR LMDTNTKGNK RSRTRTDSYS AGQSVEILDG 2460

VELGEPAHKK TGTTVPESIH SFIGDGLVKP EALNKKAIQI INRVRDKLTG RDFSHDDTLD 2520

VPTQVELLIK QATSHENLCQ CYIGW 2545

Nucleotide Sequence
(FASTA)

ATGCTGGGAA CAGGACCCGC CGCTGCCACC ACAGCTGCCG CCACCTCCAG CAACGTGAGC 60

GTCCTGCAGC AGTTTGCCAG TGGTCTGAAG AGCCGGAATG AGGAGACCAG GGCCAAAGCT 120

GCAAAGGAGC TCCAGCACTA TGTCACCATG GAGCTTCGCG AGATGAGTCA AGAGGAGTCT 180

ACTCGATTCT ATGATCAGCT GAACCATCAC ATTTTTGAAT TGGTTTCTAG CTCCGATGCC 240

AATGAGAGGA AAGGTGGCAT CTTGGCCATC GCCAGCCTCA TAGGAGTAGA AGGTGGGAAT 300

GCCACACGTA TCGGCAGGTT TGCCAACTAC CTTCGTAACC TGCTCCCCTC CAATGACCCA 360

GTTGTCATGG AAATGGCATC CAAGGCCATT GGGCGTCTTG CCATGGCAGG GGACACTTTC 420

ACTGCTGAAT ACGTGGAGTT TGAGGTGAAG CGAGCCCTGG AGTGGCTGGG TGCTGACCGC 480

AACGAAGGCC GGAGACACGC AGCCGTCCTG GTCCTCCGCG AGCTGGCCAT CAGTGTCCCC 540

ACCTTCTTCT TCCAGCAAGT GCAACCCTTC TTTGACAACA TTTTTGTGGC CGTGTGGGAC 600

CCCAAGCAGG CCATCCGGGA GGGAGCTGTG GCCGCTCTTC GCGCCTGTCT GATTCTCACC 660

ACCCAGCGGG AGCCCAAGGA GATGCAGAAG CCCCAGTGGT ACCGGCACAC CTTTGAAGAA 720

GCAGAGAAAG GGTTTGACGA GACCTTGGCC AAAGAGAAGG GCATGAATCG GGATGATCGC 780

ATCCACGGCG CCTTGCTGAT CCTCAACGAG CTGGTCCGCA TCAGCAGCAT GGAGGGAGAG 840

CGTCTGAGAG AAGAAATGGA AGAGATCACG CAGCAGCAGC TGGTGCACGA CAAGTACTGC 900

AAGGACCTCA TGGGCTTCGG GACGAAGCCT CGCCACATCA CCCCCTTCAC CAGTTTCCAG 960

GCCGTGCAGC CCCAGCAGTC CAACGCCCTG GTGGGGCTGC TGGGGTACAG CTCGCACCAG 1020

GGCCTCATGG GATTCGGGGC TTCCCCCAGC CCAGCCAAGC CCACCCTGGT GGAGAGCCGG 1080

TGTTGCCGGG ACCTGATGGA GGAGAAGTTT GACCAGGTGT GCCAGTGGGT GCTGAAATGC 1140

AGGAACAGCA AGAACTCGCT GATCCAAATG ACAATCCTTA ATTTGTTGCC CCGCCTGGCC 1200

GCATTCCGAC CTTCCGCCTT CACAGATACC CAGTACCTTC AGGATACCAT GAACCATGTC 1260

CTGAGCTGTG TCAAGAAGGA GAAGGAGCGT ACTGCAGCTT TCCAAGCCCT GGGACTGCTT 1320

TCTGTGGCTG TGAGGTCAGA GTTTAAGGTC TACCTGCCTC GTGTGCTGGA CATCATCCGA 1380

GCAGCGCTGC CTCCTAAGGA CTTTGCCCAC AAGAGGCAGA AGGCAATGCA GGTGGATGCC 1440

ACAGTGTTCA CGTGCATCAG CATGCTGGCG CGAGCAATGG GGCCAGGCAT CCAGCAGGAC 1500

ATCAAGGAGC TGCTGGAGCC CATGCTGGCA GTGGGACTGA GCCCTGCCCT CACCGCAGTG 1560

CTCTACGACC TGAGCCGCCA GATTCCCCAG CTGAAGAAGG ACATCCAGGA TGGGCTGCTG 1620

AAGATGCTGT CCCTGGTCCT TATGCACAAA CCCCTCCGGC ACCCGGGCAT GCCCAAGGGC 1680

CTGGCCCACC AGCTGGCCTC CCCTGGCCTT GCCACCCTCC CTGAGGCCAG TGATGTGGGC 1740

AGCATCACTC TTGCCCTCCG AACTCTTGGC AGCTTTGAAT TTGAAGGCCA CTCCCTGACC 1800

CAGTTTGTCC GCCACTGTGC GGATCATTTC CTGAACAGTG AGCACAAGGA GATCCGCATG 1860

GAGGCCGCCC GCACCTGCTC CCGCCTGCTC ACCCCCTCCA TCCACCTCAT CAGCGGCCAC 1920

GCTCACGTGG TGAGCCAGAC CGCAGTGCAG GTGGTGGCCG ACGTGCTCAG CAAGCTGCTC 1980

GTGGTTGGGA TAACCGACCC CGACCCCGAC ATCCGCTACT GTGTGTTGGC GTCCCTGGAT 2040

GAGCGCTTTG ATGCACACCT GGCCCAGGCA GAGAATTTGC AGGCGCTGTT TGTGGCCCTG 2100

AACGATCAGG TGTTTGAGAT CCGGGAGCTG GCCATCTGCA CCGTGGGCAG GCTCAGCAGC 2160

ATGAACCCGG CCTTCGTCAT GCCCTTCCTG CGCAAGATGC TCATCCAGAT TTTGACAGAG 2220

CTGGAGCACA GTGGCATCGG GAGAATCAAG GAACAGAGTG CCCGCATGCT GGGGCACCTG 2280

GTCTCCAATG CCCCCCGACT CATCCGCCCC TACATGGAGC CTATTCTGAA GGCTTTAATT 2340

TTGAAACTGA AAGATCCAGA CCCTGATCCG AACCCTGGCG TGATCAATAA TGTCCTGGCC 2400

ACAATAGGAG AACTGGCCCA GGTTAGTGGT CTGGAAATGA GGAAGTGGGT TGATGAGCTT 2460

TTCATTATCA TCATGGACAT GCTCCAGGAT TCCTCTCTGT TGGCCAAAAG GCAGGTGGCT 2520

TTGTGGACCC TGGGGCAACT GGTGGCCAGC ACTGGCTATG TGGTGGAGCC CTACAGGAAG 2580

TACCCCACCT TGCTAGAGGT GCTGCTGAAT TTTCTGAAGA CTGAGCAGAA CCAGGGCACG 2640

CGGAGAGAGG CTATCCGTGT GTTAGGACTG TTAGGGGCTT TGGATCCCTA CAAGCACAAA 2700

GTGAACATCG GCATGATTGA CCAGTCCCGG GATGCCTCTG CTGTCAGCCT GTCTGAATCC 2760

AAGTCAAGTC AGGACTCCTC TGATTACAGC ACCAGTGAAA TGCTGGTCAA CATGGGAAAC 2820

CTGCCCCTGG ATGAATTCTA CCCCGCCGTG TCCATGGTGG CCCTGATGCG GATCTTCCGG 2880

GACCAGTCCC TCTCTCACCA TCACACCATG GTTGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCCCTGGGGC TCAAGTGTGT GCAGTTCCTG CCCCAGGTCA TGCCTACATT CCTTAATGTC 3000

ATCCGGGTCT GTGACGGGGC CATCCGGGAA TTTCTGTTCC AGCAGCTGGG CATGTTGGTG 3060

TCCTTCGTGA AGAGCCACAT CAGACCTTAC ATGGATGAGA TCGTCACCCT CATGCGAGAG 3120

TTCTGGGTCA TGAACACCTC AATCCAGAGC ACGATCATCC TTCTCATCGA GCAAATCGTG 3180

GTAGCGCTTG GGGGCGAGTT TAAGCTCTAC CTGCCCCAGC TGATCCCGCA CATGCTGCGC 3240

GTCTTCATGC ACGACAACAG CCCGGGCCGC AGCGTCTCTA TCAAGCTGCT GGCAGCAATC 3300

CAGCTGTTTG GTGCCAACCT GGACGACTAC CTGCACTTGT TGTTGCCTCC GATCGTGAAG 3360

CTGTTTGATG CCCCTGAAGT CCCACTCCCA TCCCGAAAGG CAGCGTTGGA GACGGTGGAT 3420

CGCCTGACCG AGTCCCTGGA TTTCACGGAC TATGCCTCCC GGATCATTCA CCCAATTGTT 3480

CGAACCCTGG ATCAGAGCCC AGAACTGCGT TCTACAGCCA TGGACACCCT GTCTTCACTT 3540

GTCTTTCAGC TGGGAAAGAA GTACCAAATT TTCATTCCAA TGGTGAACAA AGTACTGGTG 3600

CGTCACCGAA TCAACCACCA GCGCTACGAT GTGCTCATCT GCAGAATTGT CAAGGGATAT 3660

ACCCTGGCTG ATGAAGAGGA GGACCCGCTG ATTTACCAGC ACCGGATGCT GAGGAGTGGC 3720

CAGGGGGATG CACTGGCCAG TGGACCAGTT GAAACGGGAC CCATGAAGAA ACTGCACGTC 3780

AGCACCATCA ACCTCCAAAA GGCCTGGGGA GCTGCCAGAA GGGTCTCCAA AGATGACTGG 3840

CTGGAGTGGC TGAGACGGCT GAGCCTGGAG CTGCTGAAGG ACTCCTCCTC CCCCTCGCTG 3900

CGCTCCTGCT GGGCCCTCGC GCAGGCCTAT AACCCAATGG CCAGGGACCT CTTCAATGCT 3960

GCGTTTGTGT CCTGTTGGTC GGAATTGAAT GAAGACCAGC AGGATGAGCT CATCAGAAGC 4020

ATCGAACTGG CCCTCACCTC TCAGGATATC GCTGAAGTCA CGCAGACCCT CTTAAACCTG 4080

GCTGAGTTCA TGGAGCACAG TGACAAGGGG CCCTTGCCAT TGAGAGATGA TAATGGCATT 4140

GTCCTGCTGG GTGAGAGAGC TGCCAAGTGC CGCGCGTATG CCAAAGCACT GCACTACAAA 4200

GAGCTGGAGT TCCAGAAGGG TCCCACGCCC GCCATCCTAG AGTCCCTCAT CAGCATTAAT 4260

AATAAGCTGC AGCAGCCCGA GGCCGCCGCC GGGGTGTTAG AATATGCCAT GAAACACTTT 4320

GGAGAGCTGG AGATCCAGGC CACGTGGTAT GAGAAACTGC ATGAGTGGGA GGACGCTCTT 4380

GTGGCCTATG ACAAGAAGAT GGACACCAAC AAGGATGACC CGGAGCTGAT GCTGGGCCGC 4440

ATGCGCTGCC TGGAAGCCTT GGGGGAGTGG GGGCAGCTCC ACCAGCAGTG CTGTGAAAAA 4500

TGGACGCTGG TGAATGACGA GACCCAAGCC AAGATGGCCC GGATGGCTGC TGCAGCTGCA 4560

TGGGGCTTAG GTCAGTGGGA CAGTATGGAA GAGTACACCT GTATGATACC TCGGGACACC 4620

CACGATGGGG CGTTTTACAG AGCCGTTCTG GCGTTACATC AGGACCTCTT CTCCTTGGCA 4680

CAGCAGTGCA TCGACAAGGC CAGGGACCTG CTAGATGCTG AGTTGACTGC CATGGCAGGA 4740

GAGAGCTACA GTCGGGCGTA TGGGGCCATG GTTTCTTGCC ATATGCTGTC CGAGCTGGAG 4800

GAGGTTATCC AGTACAAACT TGTCCCCGAG CGACGAGAGA TCATCCGCCA GATCTGGTGG 4860

GAGAGACTGC AGGGCTGCCA ACGGATCGTG GAGGACTGGC AGAAAATCCT AATGGTGCGG 4920

TCCCTTGTGG TCAACCCTCA TGAGGACATG AGGACGTGGC TCAAGTACGC AAGCCTGTGT 4980

GGCAAGAGCG GCAGGCTGGC TCTTGCTCAC AAAACCTTGG TGTTGCTCCT GGGTGTTGAT 5040

CCATCTCGGC AACTTGACCA TCCTCTGCCC ACAGTTCACC CTCAGGTGAC CTATGCCTAC 5100

ATGAAAAACA TGTGGAAGAG TGCACGGAAG ATCGACGCTT TCCAGCACAT GCAGCACTTC 5160

GTGCAGACGG TGCAGCAGCA GGCCCAGCAC GCCGTCGCCA CAGAGGACCA GCAGCACAAG 5220

CAAGAACTGC ACAAGCTCAT GGCCCGGTGT TTCCTGAAGC TTGGGGAGTG GCAGCTGAAC 5280

CTGCAGGGCA TCAACGAGAG CACCATCCCC AAGGTGCTGC AGTACTACAG CGCCGCCACC 5340

GAGCACGACC GCAGCTGGTA CAAGGCCTGG CATGCATGGG CAGTGATGAA TTTCGAAGCT 5400

GTGCTCCACT ACAAACATCA GAACCAAGCC CGCGATGAGA AGAAGAAACT GCGGCATGCC 5460

AGCGGCGCCA ACATCACCAG CGCCACCACT GCTGCCACCA CTGCTGCCAC TGCCACTGCC 5520

ACCGCCAGCA CCGAGGGCAG CAACAGTGAG AGTGAAGCCG AGAGCACAGA GAACAGCCCC 5580

ACCCCATCCC CTCTGCAGAA GAAGGTCACT GAGGACTTGT CCAAAACCCT CTTGCTCTAC 5640

ACCGTCCCCG CCGTCCAAGG CTTCTTCCGT TCTATCTCCT TGTCTCGGGG CAACAACCTC 5700

CAGGACACTC TCAGAGTCCT TACCTTGTGG TTTGATTATG GTCACTGGCC GGATGTCAAT 5760

GAAGCCTTGG TGGAAGGGGT GAAAGCCATC CAGATTGATA CGTGGTTACA GGTTATTCCT 5820

CAGCTCATCG CAAGAATAGA TACACCCAGG CCCTTGGTCG GACGGCTCAT CCACCAGCTT 5880

CTGACTGACA TTGGTCGGTA CCACCCCCAG GCCCTCATCT ACCCCTTGAC GGTGGCTTCT 5940

AAGTCTACCA CGACAGCCCG TCACAATGCG GCCAACAAGA TTCTGAAGAA CATGTGTGAG 6000

CACAGTAACA CCCTGGTCCA GCAGGCCATG ATGGTGAGTG AGGAGCTGAT CCGCGTGGCC 6060

ATCCTCTGGC ACGAGATGTG GCACGAAGGC CTGGAAGAGG CGTCTCGTTT GTACTTCGGG 6120

GAGAGGAATG TGAAAGGCAT GTTTGAGGTG CTGGAGCCCC TGCATGCGAT GATGGAACGG 6180

GGCCCCCAGA CGCTGAAGGA AACGTCCTTT AATCAGGCAT ATGGCCGAGA TTTGATGGAG 6240

GCTCAGGAGT GGTGCCGGAA GTACATGAAA TCAGGGAATG TCAAGGACCT CACTCAAGCC 6300

TGGGACCTCT ACTACCACGT GTTCAGACGG ATCTCGAAGC AGCTGCCCCA GCTCACTTCC 6360

TTAGAGCTGC AGTATGTTTC CCCCAAACTT CTGATGTGCC GGGACCTTGA ATTGGCTGTA 6420

CCAGGAACAT ACGACCCCAA CCAGCCAATC ATTCGCATTC AGTCCATCGC CCCATCTTTG 6480

CAAGTCATCA CGTCCAAGCA GAGACCCCGG AAGTTGACTC TCATGGGCAG CAACGGCCAT 6540

GAGTTTGTCT TCCTCCTGAA AGGCCATGAA GACCTGCGGC AGGATGAGCG AGTGATGCAG 6600

TTGTTTGGCC TGGTCAACAC CCTCCTGGCC AACGACCCAA CGTCCCTCCG CAAAAACCTC 6660

AGCATCCAGA GGTACGCCGT CATCCCTTTG TCGACTAACT CGGGCCTCAT CGGCTGGGTG 6720

CCGCACTGTG ACACGCTGCA CGCACTCATC CGGGACTACC GCGAGAAGAA GAAGATCCTC 6780

CTCAACATCG AGCATCGCAT CATGCTGCGA ATGGCTCCGG ACTATGACCA CCTGACGCTG 6840

ATGCAGAAGG TGGAGGTGTT CGAGCATGCT GTCAACAACA CAGCGGGTGA TGACCTGGCC 6900

AAGCTGCTGT GGCTGAAGAG CCCCAGCTCG GAGGTATGGT TTGACCGAAG AACCAATTAT 6960

ACTCGTTCGT TAGCAGTCAT GTCCATGGTT GGATATATTT TGGGCCTGGG AGATAGGCAC 7020

CCGTCCAACC TGATGCTCGA CCGGCTCAGT GGGAAGATCC TGCACATCGA CTTCGGGGAC 7080

TGCTTTGAGG TTGCTATGAC CAGAGAAAAG TTTCCAGAGA AGATTCCCTT TAGACTGACA 7140

AGAATGTTGA CCAATGCTAT GGAGGTAACA GGTCTGGATG GGAACTACAG AATCACCTGC 7200

CACACCGTGA TGGAAGTGCT TCGGGAACAC AAGGACAGCG TCATGGCTGT GCTGGAAGCC 7260

TTTGTCTATG ACCCCTTGCT AAACTGGAGG CTGATGGACA CAAATACCAA AGGCAACAAG 7320

AGATCCCGGA CAAGGACAGA CTCCTACTCT GCAGGCCAGT CAGTAGAAAT TTTGGATGGT 7380

GTGGAACTTG GGGAACCAGC TCATAAGAAA ACGGGGACCA CGGTGCCAGA ATCTATTCAC 7440

TCGTTCATTG GAGACGGCTT GGTGAAACCA GAAGCCCTAA ATAAGAAGGC TATTCAGATC 7500

ATCAACAGGG TTCGAGACAA GCTCACCGGC CGGGACTTCT CACATGACGA TACCTTGGAC 7560

GTCCCAACAC AAGTGGAGCT GCTCATCAAA CAAGCCACAT CCCATGAGAA CCTCTGCCAG 7620

TGTTACATCG GCTGG 7635

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2153  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2212

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2213  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2265

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2266  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2324

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+++

Q: 2325  AVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLT  2384

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2385  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2444

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2445  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2477

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDRHPS NLMLDRLSGK ILHIDFGDCF EVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013