EPS-CAP-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAP-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	189.5	9.1E-56	784	1030	247

Status

Unreviewed

Ensembl Protein

ENSCPOP00000010931

UniProt Accession

H0VKS9;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000012158	ENSCPOP00000010931	ENSCPOT00000012274

Organism

Cavia porcellus

Functional Description

Protein Length

1322

Protein Sequence
(FASTA)

MKRNGSRNCL NRRNRFGSRE RDWLREDVKR GCVYLYGADT TTATTSTTST SSSSSSTSSD 60

LHLVLCTVET PVSEICAGEG RESLYLQLHG DLVRRLEPTE RPLQIVYDYL SRLGFEDPVR 120

IQEEATNPDL GCMIRFYGEK PCQMDHLDRI LLSGVYNVRK GKTQLHKWAE RLVVLCGTCL 180

IVSSVKDCQT GKMHILPLVG GKIEEVKRRQ HSLAFSSAGA QAQTYHVSFE TLAEYQRWQR 240

QASKVVSQRI STVDLSCYSL EEVPEHLFYS QDITYLNLRH NFMQLERPGG LDTLYKFSQL 300

KGLNLSHNKL GLFPVLLCEI STLTELNLSC NGFHDLPSQI GNLLNLQTLC LDGNFLNTLP 360

EELGNLQQLS SLGISFNNFS YIPGVYEKLT MLDKVVMAGN YLEVLDLGVL SRMSHIKHVD 420

LRMNHLKTLV FENLEGNKYI THMDVRDNQL TDLDLSSLCS LEQLHCERNQ LRELTLSGFS 480

LRTLYAGSNR LTAVNVYPVP HLLTSLELSR NLLECIPDWA CEAKKLEILD MSYNLLTEVP 540

IRILSSLSLR KLMVGHNHVH NLPALAEHIP LEVLDLQHNV LTRLPDTLFS KALNLRYLNA 600

SANSLEFLPS ACTGEESLSM LQLLYLTNNL LTDQCIPVLT GHPHLRILHL ANNQLQTFPA 660

SKLNKLEQLE ELNLSGNKLK TIPTTIANCK RLHTLVAHSN NISIFPEILQ LPQIQFVDLS 720

CNDLTEILIP EALPATLQDL DLTGNTNLVL EHKTLDMFSH ITTLKIDQKP LPTTDSTVTS 780

TFWSHGLAEM AGQRNKLCVS TLAMDNFAEG VGAVYGMFDG DRNEELPRLL QCTMADVLLE 840

EIQQSTNDTV FMTSTFLVSH RKLGMAGQKL GSSALLCYIR PDTADPTGSF ILTVANVGTC 900

QAVLCRGGKP VPLSKVFSLE QDPEEAQRVK DQKAIITEDN KVNGVTCCTR MLGCTYLYPW 960

ILPKPHISST SLTIQDELLI LGNKTLWEHL SYTEAVNAVR HVQDPLAAAK KLCTLAQSYG 1020

CQDNVGAMVV YLNIGEEGCT CEMNGLTLPG PVGFPSTTTI KDAPKPTTPS SSSGIASEFS 1080

SEMSTSEVSS EVGSTASDEH NAGGLESGLV PRPERRCSLH PVPTSGVFQR QPSCATFSSN 1140

QSDNGLDSDD DQPVEGVITN GSKVEVEVDI HCCRGRDLEN SPILKEHSST PCPEEHPRGL 1200

CFGIRRQNSV NSGILMPLNK DKMELQKSPS TSCLYGKKLS NGSIVPLEDS LNLIEVATEA 1260

PKRKTGYFAA PTQLEPEDQF VVPRDLEEEV KEQMKQHQES RPQPESHEED RTEPPEEFDT 1320

AL 1322

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG GAATTGTTTG AATAGGAGAA ATAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGAGAGAAGA CGTGAAGAGA GGCTGTGTTT ACCTTTATGG AGCTGACACA 120

ACCACTGCCA CTACAAGCAC CACCTCCACC TCTTCCTCTT CTTCCTCCAC ATCCTCTGAC 180

TTACATCTCG TCCTTTGCAC TGTAGAGACA CCAGTGTCAG AAATATGTGC TGGAGAGGGA 240

AGAGAAAGTC TTTATTTACA ACTTCATGGA GACCTGGTCA GGAGACTGGA ACCTACTGAA 300

CGACCTCTTC AGATTGTTTA TGATTACTTA TCCAGGCTGG GATTTGAGGA TCCTGTGCGG 360

ATACAGGAGG AGGCTACAAA TCCTGACCTT GGCTGTATGA TTAGATTTTA TGGTGAAAAA 420

CCATGCCAGA TGGATCATCT GGATCGAATT CTACTGTCTG GTGTCTATAA TGTACGCAAG 480

GGAAAAACCC AGCTACATAA GTGGGCTGAA CGCCTAGTTG TTCTGTGTGG TACCTGCCTT 540

ATTGTTTCCT CAGTGAAGGA TTGTCAAACT GGAAAGATGC ACATTTTGCC TCTGGTTGGG 600

GGAAAGATAG AAGAAGTGAA GCGACGACAG CATTCCCTTG CATTCAGCTC AGCTGGAGCC 660

CAAGCTCAGA CCTATCACGT CAGCTTTGAG ACTTTGGCAG AGTACCAGAG ATGGCAGCGG 720

CAAGCATCTA AGGTGGTGTC CCAGCGAATC AGTACTGTGG ATCTTTCATG TTACAGCCTT 780

GAGGAGGTTC CTGAACATCT CTTCTACAGT CAAGATATCA CCTACCTCAA TCTGCGACAC 840

AACTTCATGC AGTTAGAAAG ACCAGGGGGC CTCGACACAC TCTACAAATT TTCTCAACTG 900

AAGGGCCTGA ACTTGTCCCA CAATAAACTT GGGTTGTTCC CTGTATTGCT ATGTGAAATT 960

TCTACCCTGA CTGAGCTCAA CCTTTCCTGT AATGGATTTC ATGACCTGCC AAGTCAGATT 1020

GGCAACCTGC TAAACCTTCA AACACTCTGT CTTGATGGCA ATTTTCTGAA CACTTTACCT 1080

GAAGAATTGG GAAATCTGCA ACAGCTTTCT TCCTTGGGAA TTTCCTTCAA CAACTTTAGT 1140

TACATTCCTG GTGTTTATGA GAAACTCACA ATGTTAGATA AAGTGGTTAT GGCAGGAAAT 1200

TATCTGGAAG TCTTGGACTT AGGGGTGCTG AGCCGAATGA GCCATATCAA GCATGTGGAT 1260

TTAAGGATGA ATCACTTGAA AACCTTGGTT TTTGAAAATC TGGAAGGAAA TAAATATATC 1320

ACACACATGG ATGTGAGGGA TAATCAGTTG ACTGACTTGG ATCTTAGCTC CTTATGTAGC 1380

TTGGAGCAGC TGCATTGCGA ACGGAATCAG CTGAGGGAAC TGACACTCAG CGGCTTCTCC 1440

CTGCGAACTC TCTATGCCGG TTCAAACAGG CTAACAGCAG TGAATGTCTA CCCTGTGCCC 1500

CATTTACTCA CTTCCCTGGA ACTCTCCCGA AACCTGTTGG AGTGTATCCC TGATTGGGCC 1560

TGTGAAGCAA AGAAGCTAGA AATATTAGAT ATGAGCTATA ATCTTCTCAC AGAGGTTCCA 1620

ATAAGAATTC TGAGTAGCTT GAGTCTTAGA AAACTGATGG TGGGACACAA CCATGTCCAC 1680

AACCTCCCAG CTCTGGCGGA GCATATCCCC CTGGAGGTGC TGGATCTCCA GCATAATGTT 1740

CTCACCAGGC TGCCAGATAC CCTCTTCTCC AAGGCCTTAA ATCTCAGATA CTTGAATGCA 1800

TCTGCAAATA GTCTGGAGTT CTTGCCTTCT GCATGCACTG GGGAGGAGAG CCTGAGCATG 1860

CTGCAGCTAC TTTACCTGAC CAACAACCTC CTGACAGATC AGTGCATCCC TGTCCTGACT 1920

GGGCATCCAC ACCTGCGGAT CTTGCATCTC GCAAACAACC AGCTGCAGAC CTTTCCTGCA 1980

AGCAAACTAA ACAAATTGGA GCAATTGGAA GAACTGAATC TAAGTGGCAA CAAGCTTAAA 2040

ACCATCCCCA CAACCATAGC AAACTGCAAA AGGCTGCACA CACTTGTGGC ACACTCCAAC 2100

AACATCAGCA TTTTTCCAGA AATTCTGCAA TTGCCTCAGA TCCAGTTTGT AGACTTAAGT 2160

TGCAATGACT TGACAGAAAT CCTAATTCCA GAGGCTCTGC CTGCTACGTT ACAAGACCTT 2220

GACCTGACTG GAAATACAAA CCTGGTTCTC GAACACAAGA CTCTGGACAT GTTTAGCCAT 2280

ATCACAACCC TAAAAATTGA TCAGAAACCT TTGCCAACCA CAGATTCTAC GGTTACGTCA 2340

ACTTTTTGGA GCCATGGACT GGCTGAAATG GCAGGACAGA GAAATAAGCT GTGTGTGTCT 2400

ACCCTAGCTA TGGATAACTT TGCAGAGGGA GTAGGGGCTG TGTATGGCAT GTTTGATGGA 2460

GACCGAAATG AGGAACTTCC TCGCCTACTA CAGTGCACAA TGGCAGATGT GCTTTTGGAA 2520

GAAATACAGC AGTCAACAAA TGACACAGTT TTCATGACCA GCACCTTCTT GGTATCTCAC 2580

AGGAAGTTAG GAATGGCTGG CCAGAAGCTA GGCTCCTCTG CTCTCCTGTG CTACATCCGC 2640

CCTGACACTG CGGATCCAAC AGGCAGTTTT ATCTTGACTG TGGCTAATGT TGGCACATGC 2700

CAAGCAGTCC TATGCCGAGG TGGGAAGCCA GTACCTCTTT CTAAGGTGTT TAGCCTGGAA 2760

CAAGACCCAG AAGAGGCACA AAGAGTGAAG GACCAAAAAG CCATCATAAC AGAGGACAAC 2820

AAAGTAAATG GGGTAACTTG CTGTACTCGA ATGCTGGGTT GTACATACCT GTACCCTTGG 2880

ATCCTCCCCA AGCCTCACAT ATCTTCTACT TCACTTACCA TTCAAGATGA GCTGCTGATT 2940

CTGGGAAACA AAACATTGTG GGAACACTTG TCATACACAG AAGCTGTCAA TGCAGTACGT 3000

CATGTGCAAG ACCCACTGGC AGCTGCCAAG AAGCTGTGCA CGCTAGCACA GAGCTATGGT 3060

TGTCAGGACA ATGTGGGGGC AATGGTGGTT TATTTGAACA TTGGTGAAGA AGGCTGCACT 3120

TGTGAAATGA ATGGACTCAC CCTCCCAGGT CCTGTGGGAT TTCCTTCAAC CACTACCATC 3180

AAGGATGCCC CCAAGCCAAC CACTCCTTCC TCTAGTAGTG GTATTGCCTC AGAGTTCAGC 3240

AGTGAGATGT CTACCTCCGA GGTGAGCAGT GAGGTGGGCT CCACCGCTTC TGATGAACAC 3300

AACGCTGGAG GCCTGGAGTC TGGCTTGGTC CCAAGGCCAG AAAGGCGTTG TAGCCTCCAC 3360

CCAGTACCCA CCTCTGGGGT TTTTCAGCGC CAGCCTTCTT GTGCAACCTT TTCCAGTAAT 3420

CAGTCTGACA ATGGCCTGGA CAGTGATGAC GACCAGCCTG TTGAAGGGGT CATAACCAAT 3480

GGCAGCAAGG TGGAAGTAGA AGTAGATATC CACTGCTGCC GCGGAAGAGA TCTTGAGAAC 3540

TCTCCTATTC TGAAAGAGCA TTCTTCTACC CCATGTCCTG AGGAACACCC TAGAGGGTTG 3600

TGCTTTGGGA TCCGACGACA GAACAGTGTG AACAGTGGCA TACTTATGCC ACTGAACAAG 3660

GACAAGATGG AGTTACAGAA GTCTCCTTCC ACTTCCTGTC TGTATGGAAA GAAACTCTCC 3720

AATGGCTCTA TTGTGCCCCT AGAAGACAGT TTGAACCTCA TAGAAGTGGC CACAGAAGCA 3780

CCCAAGAGGA AAACTGGCTA CTTTGCTGCC CCCACTCAGC TGGAACCAGA GGATCAGTTT 3840

GTTGTACCTC GTGACCTGGA GGAAGAAGTG AAGGAACAAA TGAAGCAGCA CCAGGAAAGC 3900

AGGCCCCAGC CCGAATCCCA TGAAGAGGAT CGGACCGAGC CCCCAGAGGA GTTTGATACA 3960

GCTCTGTGA 3969

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ +  +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 784   SHGLAEMAGQRNKLCVSTLAMDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  838

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + +++++Fl  +++l       ++ +k Gs+a++++i+++

Q: 839   LEEIQ----QSTNDTVFMTSTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadptg  888

         ***99....78888889************......89***************9999999*

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

            l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 889   sfILTVANVGTCQAVLCRGGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  946

         99999*************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s+ lt +de liL+ + lw+++s  eav++vr+v +

Q: 947   CCTRMLGCTYLYPWILPKPHISSTSLTIQDELLILGNKTLWEHLSYTEAVNAVRHVQD--  1004

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 1005  --PLAAAKKLCTLAQSYGCQDNVGAMVV  1030

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSTLA MDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEIQ 60

QSTNDTVFMT STFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTGSFILT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISSTSLT IQDELLILGN KTLWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>