EKS-CAP-00070

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00070

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	336.1	1.5E-100	26	335	310

Status

Unreviewed

Ensembl Protein

ENSCPOP00000011406

UniProt Accession

H0VLZ5;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK19

Gene Synonyms/Alias

CDK19;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000012680	ENSCPOP00000011406	ENSCPOT00000012801

Organism

Cavia porcellus

Functional Description

Protein Length

502

Protein Sequence
(FASTA)

MDYDFKAKLA AERERVEDLF EYEGCKVGRG TYGHVYKARR KDGKDEKEYA LKQIEGTGIS 60

MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF HRASKANKKP 120

MQLPRSMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF 180

NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED 240

IKTSNPFHHD QLDRIFSVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYAN SSLIKYMEKH 300

KVKPDSKVFL LLQKLLTMDP TKRITSEQAL QDPYFQEDPL PTLDVFAGCQ IPYPKREFLN 360

EDEPEEKGDK QNQQQQNQHQ QPTAPAPQAA APPQAPPPQQ SSTQTNGTTG GVAAGMGATA 420

AGLQHSQDSG LSQVPPNKKP RLGPSGASSG GPVMPSDYQH SSSRLTYQSS VQGSSQSQST 480

LGYSSSSQQS AQYHPSHQAH RY 502

Nucleotide Sequence
(FASTA)

ATGGATTATG ATTTCAAGGC GAAGCTGGCG GCGGAGCGGG AGCGGGTGGA GGATTTGTTT 60

GAGTACGAAG GGTGCAAAGT GGGACGCGGC ACCTACGGGC ACGTCTACAA GGCGAGGCGG 120

AAAGATGGAA AAGATGAAAA GGAATATGCA TTGAAGCAAA TTGAAGGCAC AGGAATATCC 180

ATGTCAGCTT GTAGAGAGAT TGCACTTTTG CGAGAATTGA AGCATCCCAA TGTGATCGCC 240

TTACAGAAGG TGTTCCTTTC CCACAGTGAC AGGAAAGTGT GGCTGCTGTT TGATTATGCG 300

GAACACGATC TATGGCATAT AATCAAGTTT CATCGTGCAT CAAAAGCAAA TAAAAAACCC 360

ATGCAGTTGC CAAGATCTAT GGTTAAGTCA TTACTTTACC AGATTCTTGA TGGTATCCAC 420

TATCTCCATG CAAACTGGGT GCTTCACAGA GACCTTAAAC CAGCAAATAT CCTAGTAATG 480

GGAGAAGGTC CTGAGAGAGG GAGAGTCAAA ATTGCTGACA TGGGTTTTGC CAGATTATTC 540

AATTCTCCTC TAAAGCCACT AGCGGATTTG GATCCTGTAG TTGTGACATT TTGGTATCGG 600

GCTCCAGAAC TTTTGCTTGG TGCAAGGCAT TATACCAAGG CCATTGATAT CTGGGCAATT 660

GGTTGCATAT TTGCGGAGTT GTTGACTTCA GAACCTATCT TTCACTGTCG TCAGGAAGAT 720

ATAAAAACAA GCAACCCCTT TCACCACGAT CAGCTGGATC GGATATTTAG TGTCATGGGG 780

TTTCCTGCAG ATAAAGACTG GGAAGATATT AGAAAGATGC CAGAATACCC TACACTTCAA 840

AAAGACTTTA GAAGAACGAC ATATGCCAAC AGTAGCCTCA TCAAGTACAT GGAGAAACAC 900

AAGGTCAAGC CTGACAGCAA AGTGTTCCTT TTGCTTCAGA AACTCCTTAC TATGGATCCA 960

ACCAAAAGAA TTACCTCAGA GCAGGCTCTG CAGGACCCCT ACTTTCAGGA GGACCCCTTG 1020

CCGACATTAG ATGTGTTTGC TGGCTGCCAG ATCCCGTACC CTAAGCGAGA ATTCCTTAAT 1080

GAAGATGAGC CTGAAGAGAA AGGTGACAAG CAGAATCAGC AGCAGCAGAA CCAACATCAG 1140

CAGCCCACAG CCCCTGCACC CCAGGCGGCA GCCCCTCCAC AGGCACCCCC TCCGCAGCAG 1200

AGCAGCACCC AGACCAACGG GACCACAGGT GGGGTGGCAG CTGGCATGGG GGCCACGGCG 1260

GCAGGGCTGC AGCACAGCCA GGACTCCGGC CTAAGCCAGG TGCCTCCAAA CAAGAAGCCA 1320

CGGCTTGGGC CCTCGGGTGC CAGCTCAGGC GGGCCCGTCA TGCCCTCGGA CTACCAGCAC 1380

TCTAGTTCTC GCCTGACTTA CCAAAGCAGC GTTCAGGGAT CCTCTCAGTC CCAGAGCACC 1440

CTGGGCTACT CCTCATCGTC TCAGCAGAGT GCGCAGTACC ACCCATCTCA CCAGGCCCAC 1500

CGGTAC 1506

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vyka++k+  +++ +AlK+i    e +g++++a+rEi+ll+elkh+n++ L

Q: 26    KVGRGTYGHVYKARRKDgkDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL  81

         79************986436678******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k ++++       +l++++vksll+q+l+g++y

Q: 82    QKVFLsHSDRKVWLLFDYAEHDLWHIIKFHRASkankkpmQLPRSMVKSLLYQILDGIHY  141

         ****94555*********************9999999999********************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 142   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  201

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 202   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpfhHDQLDRIFSVMGF  261

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pey    k+f+++++   +l ++++k k    +k + ll+kll++dp+

Q: 262   PADKDWEDIRKMPEYPtlqKDFRRTTYAnsSLIKYMEKHKvkpdSKVFLLLQKLLTMDPT  321

         ***************965457777666544666666443333545689************

S: 271   kRisakealqhkyf  284

         kRi++++alq++yf

Q: 322   KRITSEQALQDPYF  335

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKARRKDGKD EKEYALKQIE GTGISMSACR EIALLRELKH PNVIALQKVF 60

LSHSDRKVWL LFDYAEHDLW HIIKFHRASK ANKKPMQLPR SMVKSLLYQI LDGIHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PFHHDQLDRI FSVMGFPADK 240

DWEDIRKMPE YPTLQKDFRR TTYANSSLIK YMEKHKVKPD SKVFLLLQKL LTMDPTKRIT 300

SEQALQDPYF 310

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013