EKS-CAP-00501

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00501

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	363.3	7.9E-109	15	305	291

Status

Unreviewed

Ensembl Protein

ENSCPOP00000011989

UniProt Accession

H0VNG0;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK15

Gene Synonyms/Alias

MAPK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000013318	ENSCPOP00000011989	ENSCPOT00000013448

Organism

Cavia porcellus

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MCTAEVDRHV VQRYLLKRQL GKGAYGIVWR AVDRRTGEVV AIKKIFDAFR NKTDAQRTFR 60

EIMLLQEFGD HPNIIRLLDV IWAENNTDIY LVFECMDTDL NTIIQKENLL EDIHKRYIFY 120

QLLRATKFIH SGNVIHRDQK PSNVLLDANC LVKLCDFGLA RSISNFPEGP KNQALTEYVA 180

TRWYRAPEVL LSSRCYTPGV DVWSLGCILG EMLRGQPLFP GSSTLHQLQL ILETIPPPSA 240

EDLLALGSGY SDLILHCLGS RPRQRLDALL PPDTPPEALD LLRRLLVFAP DKRLSAAQAL 300

KHPYVQRFHC PDQEWTRGTD PKLVVHEGDQ LSASEYRSRL YKMILEWRDN SRGPRKEGIA 360

LGTEPRASCT QGHLLKPRVN PQLPTGTPTR NSGPRPQNSL GQDPGHGVPV PDAPRAARNI 420

PRQGLASSLQ PQALGRRDRT SGVAKEPPLE PSGVKPSVKG IEPSLTMQAA AQMAHQALIR 480

GHPARVVFWA QVPPRAPREA PEPRPGRRMF STSASWGAQG VARAVLGGYS QAYGTVCHSA 540

LDRLPLFPGP HG 552

Nucleotide Sequence
(FASTA)

ATGTGTACCG CCGAGGTGGA CAGGCATGTA GTCCAGAGAT ACCTGCTCAA GCGGCAGCTC 60

GGGAAGGGGG CCTATGGTAT TGTGTGGAGG GCAGTGGATC GGAGGACTGG TGAGGTTGTG 120

GCCATCAAGA AAATCTTTGA TGCCTTTAGG AATAAGACAG ATGCTCAGAG AACATTCCGG 180

GAAATCATGC TGCTCCAGGA ATTTGGAGAC CATCCCAACA TCATCCGCCT CCTCGATGTG 240

ATTTGGGCAG AGAACAATAC AGACATATAC CTGGTATTTG AGTGCATGGA CACTGACCTG 300

AACACCATCA TCCAGAAGGA AAACCTGTTA GAAGATATCC ACAAGCGCTA CATCTTCTAC 360

CAGCTCCTAC GGGCTACCAA GTTCATCCAT TCGGGGAATG TCATCCATCG GGACCAGAAG 420

CCATCCAATG TTCTCCTGGA TGCCAACTGC TTGGTGAAGC TCTGTGACTT TGGTCTGGCC 480

CGCTCCATCA GCAACTTCCC AGAGGGGCCC AAGAACCAGG CCCTGACAGA GTACGTGGCC 540

ACACGCTGGT ACCGGGCTCC AGAAGTGCTC CTGTCTTCAC GCTGCTATAC CCCTGGAGTA 600

GACGTATGGA GTCTCGGCTG CATCTTGGGA GAGATGCTGC GAGGGCAGCC CCTGTTCCCA 660

GGCTCATCTA CGCTGCACCA GCTGCAACTG ATCCTGGAGA CCATCCCGCC TCCGTCTGCA 720

GAGGACCTCC TGGCTCTTGG CTCAGGGTAC AGCGACTTGA TTCTGCACTG CCTAGGATCC 780

AGGCCACGAC AGAGACTGGA TGCCCTCCTG CCACCAGACA CTCCTCCAGA GGCTCTGGAT 840

CTCCTCAGGC GACTCCTGGT GTTTGCCCCA GACAAGAGGC TTAGTGCAGC CCAGGCGCTC 900

AAGCACCCCT ATGTGCAGAG GTTCCACTGC CCTGACCAAG AGTGGACACG GGGTACGGAC 960

CCGAAGCTCG TGGTGCATGA AGGAGACCAG CTCTCTGCCT CGGAGTACCG CAGCCGCCTC 1020

TATAAGATGA TCTTGGAGTG GAGAGACAAC AGCCGTGGCC CAAGAAAGGA AGGCATTGCC 1080

CTGGGGACAG AGCCTCGGGC CTCCTGCACA CAGGGGCATC TTCTCAAGCC CCGAGTCAAT 1140

CCCCAGCTTC CTACTGGAAC ACCTACCCGA AACTCTGGAC CCAGGCCACA GAATAGCCTG 1200

GGTCAAGATC CAGGGCATGG TGTGCCTGTC CCAGATGCTC CCAGGGCAGC CAGGAACATC 1260

CCAAGGCAGG GCTTAGCCTC CTCGCTCCAA CCTCAGGCCC TAGGCAGGAG GGACAGGACT 1320

TCTGGGGTGG CCAAGGAGCC TCCCTTGGAA CCCTCTGGGG TGAAGCCAAG TGTGAAAGGC 1380

ATAGAGCCCT CTCTGACTAT GCAGGCTGCT GCCCAGATGG CCCACCAGGC CCTGATTCGA 1440

GGCCACCCAG CCCGGGTTGT GTTCTGGGCA CAGGTCCCTC CCAGAGCTCC CAGAGAAGCC 1500

CCAGAGCCCC GACCTGGTCG GAGGATGTTC AGCACCTCAG CCTCATGGGG GGCCCAGGGC 1560

GTTGCCAGAG CTGTGCTCGG CGGCTACTCC CAGGCCTATG GGACTGTGTG CCACTCAGCA 1620

CTGGACCGCC TGCCTCTCTT CCCTGGACCC CATGGGTGA 1659

Domain Profile

S: 2     eslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkel.kheNi  60

           +++lg+Gayg+v++avd+rt+e vaikk++++f+++t+a+rt+RE++ll+e+ +h+Ni

Q: 15    LLKRQLGKGAYGIVWRAVDRRTGEVVAIKKIFDAFRNKTDAQRTFREIMLLQEFgDHPNI  74

         56799*******************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylH  119

         i+lldv+ +e+     +d+Ylv+e m+tdL+++i+++  l+d h ++++yq+lr++k++H

Q: 75    IRLLDVIWAEN----NTDIYLVFECMDTDLNTIIQKEnLLEDIHKRYIFYQLLRATKFIH  130

         *******9999....89*******************9889999*****************

S: 120   sanviHrDlKPsNllvnedcelkildFGlarsadkekekk....lteyvatrwYraPeil  175

         s nviHrD+KPsN+l++++c +k++dFGlars ++  e      lteyvatrwYraPe+l

Q: 131   SGNVIHRDQKPSNVLLDANCLVKLCDFGLARSISNFPEGPknqaLTEYVATRWYRAPEVL  190

         ********************************776655444567****************

S: 176   lslkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkiesee  235

         ls++ yt  vD+Ws+GCIl+E+l+g+plfpg+++++ql++ile+++ ps+e+l ++ s

Q: 191   LSSRCYTPGVDVWSLGCILGEMLRGQPLFPGSSTLHQLQLILETIPPPSAEDLLALGSGY  250

         ***********************************************************9

S: 236   arnyikslpkkkkkdfeelfpk.aseealdLleklLvldpdkRisveeaLehpYl  289

            +++ l +++++ +++l+p  + +ealdLl++lLv++pdkR+s+++aL+hpY+

Q: 251   SDLILHCLGSRPRQRLDALLPPdTPPEALDLLRRLLVFAPDKRLSAAQALKHPYV  305

         999999*************9875889****************************7

Domain Sequence
(FASTA)

LLKRQLGKGA YGIVWRAVDR RTGEVVAIKK IFDAFRNKTD AQRTFREIML LQEFGDHPNI 60

IRLLDVIWAE NNTDIYLVFE CMDTDLNTII QKENLLEDIH KRYIFYQLLR ATKFIHSGNV 120

IHRDQKPSNV LLDANCLVKL CDFGLARSIS NFPEGPKNQA LTEYVATRWY RAPEVLLSSR 180

CYTPGVDVWS LGCILGEMLR GQPLFPGSST LHQLQLILET IPPPSAEDLL ALGSGYSDLI 240

LHCLGSRPRQ RLDALLPPDT PPEALDLLRR LLVFAPDKRL SAAQALKHPY V 291

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013