EKS-CAP-00225

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00225

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	522.2	2.7E-157	389	662	274

Status

Unreviewed

Ensembl Protein

ENSCPOP00000014058

UniProt Accession

H0VTQ2;

Protein Name

Protein Synonyms/Alias

Gene Name

MAST3

Gene Synonyms/Alias

MAST3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000015590	ENSCPOP00000014058	ENSCPOT00000015742

Organism

Cavia porcellus

Functional Description

Protein Length

1321

Protein Sequence
(FASTA)

MKSRRDKLHI PALTLDLSPS SQSPALLVPG SRCAEVFPSQ GLQPLSCRSG NRKSLVVGTP 60

SPTLSRPLSP LSIPTAGSSP LDSPRNFSAA SAINFPFARR ADGRRWSLAS LPSSGYGTNT 120

PSSTVSSSSS SRERLHQLPF QPTPDELRFL SKHFRSSESV VDEEGGRSPR LRPRSRSLSP 180

GRATGSFDNE IVMMNHVYRE RFPKATAQME GRLQEFLAAY APGARLALAD GVLGFIHHQI 240

VELARDCLAK SGEALVTSRY FLEMQEKLER LLQDAHDRSD SEEVGFIVQL VRKLLIIISR 300

PARLLECLEF DPEEFYHLLE AAEGQAREGQ GIKTDLPQYI IGQLGLAKDP LEEIGPLSDI 360

DGGQRPAPES PENRALGGPS RRKPCESDFE TIKLISNGAY GAVYLVRHRH TRQRFAIKKI 420

NKQNLMLRNQ IQQVFVERDI LTFAENPFVV SMFCSFETRR HLCMVMEYVE GGDCATLLKN 480

MGPLPVDMAR MYFAETVLAL EYLHNYGIVH RDLKPDNLLI TSLGHIKLTD FGLSKIGLMS 540

MATNLYEGHI EKDAREFVDK QVCGTPEYIA PEVIFCQGYG KPVDWWAMGI ILYEFLVGCV 600

PFFGDTPEEL FGQVVSDEIM WPEGEEALPA DAQDLITRLL RQSPMDRLGT GGTHEVKQHP 660

FFLGLDWAGL LRHKAEFVPQ LEAEDDTSYF DTRSERYRHL GSEDEETNDE ESSTEIPQFS 720

SCSHRFSKVY SSSEFLAVQP TPTFAERSCS VDREEGWDRG SDGDGGPRLS TEVRLRSWTS 780

SGSSCYSSSS QLDRGPSPSL LSNISLDTMP KFAFSSEDEA AGLTPVDPKK PVFILGEPDP 840

PPPTTPVTPK PSSLSADPVG LSHARLRSNS TGARHSTPRA LDTGRGRRLG ATRDPAIDKP 900

KAAPSGGSSS SSGGRVPKSA SVSALSLIIT TDDGSGGPLM SPLSPRSLSS NPSSRDSSPS 960

RDPSPVCSSL RPPVVIHSSG KKYGFSLRAI RVYMGDSNVY TVHHVVWSVE EGSPAQEAGL 1020

RSGDLVTHIN GESVLGLVHR DVVELLLKSG NKISLRTTAL ENTSIRVGPA RRDAANGRMA 1080

RRSKRSRRRE TQDRRKSLFK KISKQSSVLH TSRSFSSGLH HSLSSSESLP GSPTHSLSPS 1140

PTTPCRSPAP DGRTNTDTVS PPSGSPNSSS PASPATACHA RPSSLHGLAA KLGPPRHKGG 1200

RRKSTSSIPP SPLACLTAPT PPPRSPSPLP GHTPTPARSP MLRRGQSADK LGMGERPSER 1260

PDSELVIMRR LHLSERRDSF KKQEAVQEVS FDEEAPGAAP PPVSVPQIAV QGAEPAPISK 1320

D 1321

Nucleotide Sequence
(FASTA)

ATGAAGTCGC GCAGGGATAA GCTGCACATC CCGGCCCTGA CCCTCGATCT GTCCCCGAGC 60

AGCCAGAGCC CCGCGCTGTT GGTGCCAGGC AGCAGATGTG CAGAAGTGTT TCCCTCCCAG 120

GGGCTTCAAC CCCTCAGCTG CCGCAGCGGA AACCGCAAAA GCTTGGTGGT TGGGACGCCG 180

TCTCCAACTC TCTCCCGGCC ATTGTCACCG CTGTCCATCC CCACCGCAGG CAGCAGCCCT 240

TTGGACAGCC CACGGAACTT CTCGGCCGCA TCCGCTATCA ACTTCCCCTT TGCCCGAAGG 300

GCTGACGGCA GAAGATGGTC CCTCGCATCC CTCCCGTCTT CCGGCTATGG AACCAATACA 360

CCCAGCTCCA CTGTCTCGTC AAGCTCATCC TCCCGGGAGC GTCTCCATCA GCTTCCCTTC 420

CAGCCGACGC CGGATGAGCT GCGCTTCCTG TCCAAGCATT TCCGCAGCTC CGAGAGCGTG 480

GTGGATGAGG AGGGTGGCCG CTCACCCCGC CTGCGCCCCC GCTCCCGCAG CCTCAGCCCG 540

GGCCGCGCCA CCGGCAGCTT TGATAATGAG ATCGTGATGA TGAACCATGT GTACCGGGAG 600

CGGTTCCCCA AGGCCACAGC TCAGATGGAG GGCAGGCTGC AGGAATTCCT GGCCGCCTAC 660

GCTCCCGGCG CCCGGCTGGC GCTGGCCGAC GGCGTCCTGG GCTTCATCCA TCACCAGATT 720

GTGGAGCTGG CCCGGGACTG CCTGGCCAAG TCCGGTGAGG CGCTGGTCAC CTCGCGCTAC 780

TTCCTGGAGA TGCAGGAGAA GCTGGAGCGG CTGCTGCAGG ATGCTCATGA CAGATCCGAT 840

AGCGAGGAGG TTGGCTTCAT CGTCCAGCTT GTCCGGAAGC TGCTGATCAT CATCTCCAGG 900

CCAGCCCGGC TCCTCGAGTG CCTGGAGTTC GACCCCGAGG AGTTCTATCA CCTGCTGGAG 960

GCTGCAGAGG GCCAGGCGCG CGAGGGCCAG GGCATCAAGA CTGACCTGCC GCAGTACATC 1020

ATTGGGCAGC TGGGCCTTGC CAAGGACCCT CTGGAGGAGA TCGGGCCTCT GAGTGACATC 1080

GACGGAGGAC AGCGCCCTGC TCCTGAATCA CCAGAGAACC GTGCCCTGGG TGGCCCATCA 1140

CGGAGAAAGC CCTGTGAGAG TGACTTTGAG ACCATCAAGC TCATCAGCAA CGGGGCCTAC 1200

GGGGCCGTGT ACCTGGTGCG GCACCGCCAC ACGCGGCAGC GCTTCGCCAT CAAAAAGATC 1260

AACAAGCAGA ACCTGATGCT GCGGAACCAG ATCCAGCAGG TGTTCGTGGA GCGTGACATC 1320

CTCACGTTCG CCGAGAACCC TTTCGTGGTC AGCATGTTCT GCTCCTTCGA GACGCGGCGC 1380

CATCTCTGCA TGGTTATGGA GTATGTGGAA GGCGGCGACT GTGCCACGCT GCTGAAGAAC 1440

ATGGGCCCGC TGCCTGTGGA CATGGCGCGC ATGTACTTCG CCGAGACAGT GCTAGCTCTC 1500

GAGTACTTGC ACAACTACGG CATCGTGCAC CGCGACCTCA AGCCCGACAA CCTGCTCATC 1560

ACCTCGCTGG GCCACATCAA GCTGACCGAC TTTGGGCTGT CCAAGATCGG GCTCATGAGC 1620

ATGGCCACAA ACCTCTATGA AGGTCACATT GAGAAGGACG CGCGCGAGTT TGTGGACAAA 1680

CAGGTGTGTG GGACCCCTGA GTACATCGCC CCCGAAGTGA TCTTCTGCCA GGGCTACGGA 1740

AAGCCTGTGG ACTGGTGGGC CATGGGAATC ATCCTCTACG AGTTCCTGGT GGGCTGTGTG 1800

CCATTCTTCG GGGACACACC AGAGGAGCTG TTTGGGCAGG TGGTCAGTGA TGAGATCATG 1860

TGGCCGGAAG GGGAGGAGGC GCTTCCAGCT GACGCCCAAG ACCTCATCAC CAGGCTGCTG 1920

CGTCAGAGCC CGATGGACCG TCTGGGCACT GGGGGTACCC ACGAAGTCAA GCAGCACCCC 1980

TTCTTCCTGG GCCTGGACTG GGCGGGGCTG CTGCGACACA AGGCCGAGTT CGTGCCACAG 2040

CTGGAGGCCG AGGATGACAC CAGCTACTTC GACACACGCT CAGAACGCTA CCGCCACCTG 2100

GGCTCCGAGG ACGAGGAGAC CAACGATGAG GAGTCCTCCA CCGAGATCCC GCAGTTCTCC 2160

TCCTGTTCCC ATCGTTTCAG CAAGGTCTAT AGCAGCTCTG AGTTCCTGGC TGTGCAGCCC 2220

ACGCCCACCT TTGCTGAAAG GAGCTGCAGC GTGGACCGGG AAGAGGGCTG GGACCGGGGC 2280

AGCGACGGGG ACGGCGGGCC CCGGCTGAGC ACTGAGGTCC GGCTGAGGTC CTGGACGTCC 2340

TCTGGGTCCT CCTGTTACTC ATCGTCATCT CAACTTGATC GGGGCCCCAG CCCATCACTC 2400

CTGAGCAACA TCAGTCTAGA CACAATGCCC AAGTTTGCCT TCTCGTCAGA GGATGAGGCA 2460

GCAGGCCTAA CCCCCGTGGA CCCCAAAAAG CCTGTCTTCA TCCTTGGGGA ACCTGACCCC 2520

CCACCACCGA CCACCCCAGT AACACCGAAA CCCTCAAGTC TTTCTGCCGA CCCGGTGGGC 2580

CTCAGCCATG CTCGGCTCCG GAGCAACAGC ACGGGTGCCC GGCACTCCAC GCCCCGGGCC 2640

TTGGACACTG GCCGGGGCCG TCGACTCGGG GCCACAAGAG ACCCTGCCAT CGACAAGCCT 2700

AAGGCTGCCC CCAGTGGGGG CAGCAGCAGC AGCAGCGGGG GCCGTGTGCC CAAGTCGGCA 2760

TCCGTGTCAG CCCTGTCCCT CATCATCACA ACAGATGATG GCAGCGGTGG CCCCCTCATG 2820

AGCCCATTGT CCCCACGTTC ACTGTCCTCA AACCCGTCCT CACGAGACTC CTCGCCAAGC 2880

CGGGACCCCT CCCCAGTGTG CAGCAGCCTG CGGCCCCCCG TGGTCATCCA CAGCTCAGGC 2940

AAGAAGTACG GCTTCAGCCT GCGTGCCATC CGTGTCTACA TGGGCGACAG CAACGTCTAC 3000

ACCGTGCACC ATGTGGTTTG GAGCGTGGAG GAGGGGAGCC CCGCACAGGA GGCTGGGCTG 3060

CGCTCAGGGG ACCTGGTCAC GCACATCAAT GGCGAGTCCG TGCTGGGCCT GGTGCATCGC 3120

GACGTGGTGG AGCTGCTGCT GAAGAGCGGG AATAAGATCT CGCTGCGAAC CACGGCACTG 3180

GAGAACACGT CCATCAGGGT GGGCCCGGCC CGCAGGGACG CAGCTAACGG GCGCATGGCG 3240

CGACGCAGCA AGCGCAGCCG GCGGCGGGAA ACTCAGGACC GGCGGAAGTC ATTGTTCAAG 3300

AAGATCTCCA AGCAGTCGTC TGTCCTGCAC ACCAGCCGCA GTTTCTCCTC CGGCCTCCAC 3360

CACTCACTGT CCTCCAGCGA GAGCCTGCCA GGGTCCCCCA CCCACAGCCT GTCGCCCAGC 3420

CCCACCACCC CTTGCCGCAG CCCAGCACCC GATGGCAGAA CCAACACAGA TACTGTGTCC 3480

CCGCCCAGCG GATCCCCAAA CTCCAGCAGT CCTGCGTCCC CTGCCACCGC CTGCCATGCC 3540

CGCCCCAGCT CCCTGCACGG CCTGGCTGCC AAGCTGGGGC CGCCTCGGCA CAAGGGCGGG 3600

CGCCGGAAGT CCACCAGCAG CATCCCGCCC TCACCGCTGG CCTGCCTGAC CGCGCCCACC 3660

CCTCCACCAC GCTCACCCTC ACCGCTGCCA GGCCACACGC CCACCCCTGC CCGGTCCCCG 3720

ATGCTGCGCC GCGGGCAGTC AGCGGACAAG CTGGGCATGG GTGAGCGGCC GAGTGAGAGG 3780

CCTGACTCGG AGCTGGTGAT TATGCGGCGG CTGCATCTGT CCGAGCGCCG GGACTCCTTC 3840

AAGAAGCAAG AGGCCGTACA GGAGGTCAGC TTCGACGAGG AGGCACCTGG GGCAGCGCCC 3900

CCACCCGTGT CTGTGCCACA GATCGCAGTG CAGGGTGCAG AGCCCGCACC CATCAGCAAG 3960

GACTGA 3966

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         fe+iklis+GayGavylvrh++tr+rfa+kki+kq+l+l+nq+qqvf+erdil++aenpf

Q: 389   FETIKLISNGAYGAVYLVRHRHTRQRFAIKKINKQNLMLRNQIQQVFVERDILTFAENPF  448

         99**********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vvs+++s+etrr+l++vmeyveGGd+++llkn+G+l+v+mar+y+ae+vlaleylh+yGi

Q: 449   VVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGI  508

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         vhrdlkPdnllits GhikltdfGlsk+glms++tnlyeg+i+kdaref+dkqvcgtPey

Q: 509   VHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEY  568

         ************************************************************

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekdeal  240

         iaPevi+ qgygkpvdwwa+giilyeflvg+vpffgdtpeelf+qv+sdei+wPe++eal

Q: 569   IAPEVIFCQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGEEAL  628

         ************************************************************

S: 241   ssealelisellesnPrerlgtgsaaevkqhefl  274

         +++a++li++ll+++P++rlgtg+++evkqh+f+

Q: 629   PADAQDLITRLLRQSPMDRLGTGGTHEVKQHPFF  662

         ********************************97

Domain Sequence
(FASTA)

FETIKLISNG AYGAVYLVRH RHTRQRFAIK KINKQNLMLR NQIQQVFVER DILTFAENPF 60

VVSMFCSFET RRHLCMVMEY VEGGDCATLL KNMGPLPVDM ARMYFAETVL ALEYLHNYGI 120

VHRDLKPDNL LITSLGHIKL TDFGLSKIGL MSMATNLYEG HIEKDAREFV DKQVCGTPEY 180

IAPEVIFCQG YGKPVDWWAM GIILYEFLVG CVPFFGDTPE ELFGQVVSDE IMWPEGEEAL 240

PADAQDLITR LLRQSPMDRL GTGGTHEVKQ HPFF 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR015022	; MA_Ser/Thr_Kinase_dom.
IPR023142	; MAST_pre-PK_dom.
IPR001478	; PDZ.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08926	; DUF1908; 1.
PF00595	; PDZ; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00228	; PDZ; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50106	; PDZ; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013