EKS-CAP-00229

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00229

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	446.0	5.3E-134	4	285	282

Status

Unreviewed

Ensembl Protein

ENSCPOP00000015152

UniProt Accession

H0VWS4;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000021691	ENSCPOP00000015152	ENSCPOT00000026212

Organism

Cavia porcellus

Functional Description

Protein Length

399

Protein Sequence
(FASTA)

LPDYKAIGKI GEGTFSEVLK MQSLRDGGFY ACKQMKQHFD SVEQVNNLRE IQALRRLNPH 60

PNILTLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRRPL SERKIMLYMY QLCKSLDHMH 120

RNGMFHRDVK PENILIKQDV LKLGDFGSCR SVYSRQPYTE YISTRWYRAP ECLLTDGFYT 180

SKMDMWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAPKTLTKFK QSRAMSFDFP 240

FKKGSGIPLL TANLSPKCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRA SEKQAWGSRS 300

HTTFSGHMEP LGHKWQIPEA GLGQGHLLAR QSRKAPRRRE VPARLPKLPL PAVSALPVRS 360

SPALRALKFG GTCDKVNTQD TKPDPPLCRL PKIDQKGAR 399

Nucleotide Sequence
(FASTA)

CTTCCAGATT ATAAAGCAAT TGGCAAGATA GGAGAGGGGA CATTTTCGGA AGTCCTGAAG 60

ATGCAGAGCC TGCGAGACGG GGGCTTCTAT GCGTGTAAAC AGATGAAGCA GCACTTCGAC 120

AGTGTTGAGC AAGTGAACAA CCTGCGGGAG ATCCAAGCCC TGAGGCGCCT GAACCCACAC 180

CCCAACATCC TCACGCTGCA CGAGGTGGTC TTTGACAGAA AGTCTGGTTC TCTTGCATTA 240

ATATGTGAAC TTATGGACAT GAATATTTAC GAGCTCATAC GAGGGAGAAG GCGCCCGCTG 300

TCCGAGAGGA AGATCATGCT CTACATGTAC CAGTTGTGCA AGTCACTGGA CCACATGCAC 360

AGGAACGGGA TGTTCCACAG AGACGTGAAG CCCGAGAACA TTCTCATAAA GCAAGATGTC 420

CTGAAGCTCG GGGACTTCGG GTCGTGCCGA AGTGTCTACT CCAGGCAGCC GTACACGGAG 480

TACATCTCCA CCCGCTGGTA CCGGGCCCCC GAGTGCCTGC TCACTGATGG CTTCTACACC 540

TCCAAGATGG ACATGTGGAG CGCAGGCTGT GTCTTCTATG AGATCGCCAG CCTGCAGCCC 600

CTCTTCCCTG GGGTAAACGA ACTGGACCAG ATCTCCAAAA TCCACGATGT CATTGGCACA 660

CCTGCTCCGA AGACCCTTAC CAAGTTCAAA CAGTCAAGAG CTATGAGTTT TGATTTTCCT 720

TTTAAAAAGG GATCAGGAAT TCCTCTACTG ACAGCCAATT TATCCCCGAA GTGTCTCTCC 780

CTCCTGCATG CGATGGTGGC CTATGACCCG GACGAGCGCA TCGCTGCCCA CCAGGCCCTG 840

CAGCACCCCT ACTTTCAGGA GCAGAGGGCA TCCGAGAAGC AGGCCTGGGG TAGCCGCAGC 900

CACACAACCT TCTCAGGGCA CATGGAGCCA CTGGGTCACA AGTGGCAGAT CCCGGAGGCA 960

GGGCTGGGCC AGGGGCACCT CTTGGCAAGG CAGAGCCGGA AGGCGCCGCG GAGGCGAGAG 1020

GTCCCAGCCC GCCTGCCCAA GCTGCCGCTG CCGGCCGTGA GTGCCCTGCC TGTGCGCTCC 1080

AGCCCTGCAC TCAGAGCCTT GAAGTTCGGG GGCACCTGTG ATAAGGTGAA CACGCAGGAC 1140

ACCAAGCCTG ACCCGCCACT GTGTCGCCTG CCCAAGATTG ACCAGAAAGG CGCAAGG 1197

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+evl+++sl++g+ +a+k+mk++f s+e+v+nlre+++l++ln+h+ni

Q: 4     YKAIGKIGEGTFSEVLKMQSLRDGGFYACKQMKQHFDSVEQVNNLREIQALRRLNPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++sl+l++elm++n+y+li++rr+ lse+k++ ++yq++k+l+++h++g

Q: 64    LTLHEVVFDRKSGSLALICELMDMNIYELIRGRRRPLSERKIMLYMYQLCKSLDHMHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+v+s++Pyt+y+strwyraPe+ll++g+y+s+

Q: 124   MFHRDVKPENILIK-QDVLKLGDFGSCRSVYSRQPYTEYISTRWYRAPECLLTDGFYTSK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+w++Gcv++e+a+l+plfPG++e+dqi+ki++v+GtP+ k++++ +k+++a++++fp+

Q: 183   MDMWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAPKTLTK-FKQSRAMSFDFPF  241

         *********************************************9.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++ l++n+s ++l+ll++++aydPder++a+qal++pyf

Q: 242   KKGSGIPLLTANLSPKCLSLLHAMVAYDPDERIAAHQALQHPYF  285

         *******************************************9

Domain Sequence
(FASTA)

YKAIGKIGEG TFSEVLKMQS LRDGGFYACK QMKQHFDSVE QVNNLREIQA LRRLNPHPNI 60

LTLHEVVFDR KSGSLALICE LMDMNIYELI RGRRRPLSER KIMLYMYQLC KSLDHMHRNG 120

MFHRDVKPEN ILIKQDVLKL GDFGSCRSVY SRQPYTEYIS TRWYRAPECL LTDGFYTSKM 180

DMWSAGCVFY EIASLQPLFP GVNELDQISK IHDVIGTPAP KTLTKFKQSR AMSFDFPFKK 240

GSGIPLLTAN LSPKCLSLLH AMVAYDPDER IAAHQALQHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013