EKS-CAP-00451

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00451

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	345.0	2.4E-103	208	482	275

Status

Unreviewed

Ensembl Protein

ENSCPOP00000014446

UniProt Accession

H0VUS1;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100717213

Gene Synonyms/Alias

LOC100717213;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000025291	ENSCPOP00000014446	ENSCPOT00000024452

Organism

Cavia porcellus

Functional Description

Protein Length

561

Protein Sequence
(FASTA)

MDDTGVYVEP KKLNISSREE SETEGQKTTQ ESKEALSQSP ETGETRRAEI PRTPSKKIPK 60

HGTSQEEGEA CLAVLQTPGA APVTSPSTAV HAAHGSSPLQ DDKPSTSKIS LHGPLVSSSK 120

GKALSRSAKH LQLTPIHLMD EASSLSLVKV NPFTPESYKK LFLQSTGKRK TPEDPEKTDE 180

EEGQLQGLPA KKSVLRETNM ASRYEKEFLE LEKIGGGEFG IVYKCVKRLD GCIYAIKRST 240

KPVGMLSNEN TRLREVYAHA VLGQHPHVVR YYSSWAEDDR VIIQNEYCNG GSLQAAISEN 300

TKSGNHFQEP KLKDILLQIS LGLKYIHSSG LVHLDIKPSN IFICHNTRSD CPGVPEETEN 360

EADWFLSASV IYKIGDLGHV TSIKKPQVEE GDIRFLADEI FQEDYQHLPK GDIFALGLTI 420

ALAAGANTLP SCGEDWHWIR KGNFPDVPQK LTEDFHNLLK NMIHPDPKER PSAAALAKSQ 480

VLRPSLSTTE ELQRQLILEK SKIAALEREL RKIQQTRSSQ GDLHPDNPEV SAGQTESRSP 540

KHLARRKRVK SSSFIDEQSS P 561

Nucleotide Sequence
(FASTA)

ATGGATGACA CAGGTGTTTA TGTAGAGCCC AAGAAATTAA ACATTTCCTC CCGTGAAGAG 60

TCTGAGACTG AAGGGCAGAA GACAACCCAA GAGAGCAAGG AGGCCCTGAG CCAAAGCCCC 120

GAAACGGGTG AGACTAGACG TGCAGAGATT CCTAGGACAC CCTCAAAGAA AATACCCAAA 180

CATGGTACCT CTCAGGAGGA AGGTGAGGCA TGTCTAGCGG TTCTACAGAC TCCAGGGGCA 240

GCACCTGTCA CAAGTCCTTC GACAGCAGTA CATGCTGCCC ACGGAAGCAG CCCGCTGCAG 300

GATGACAAGC CCTCTACTTC CAAAATAAGT CTTCATGGTC CTCTGGTGAG TTCTTCAAAA 360

GGGAAGGCCC TTTCCCGGAG CGCTAAGCAT TTGCAGCTTA CACCTATTCA CCTCATGGAT 420

GAGGCCTCCT CACTGTCTCT AGTCAAGGTT AATCCTTTTA CTCCTGAGTC CTATAAGAAA 480

TTATTCCTTC AATCCACGGG CAAGAGGAAA ACCCCAGAAG ATCCTGAGAA AACTGATGAA 540

GAGGAAGGCC AATTACAAGG GCTTCCTGCT AAGAAAAGTG TTCTACGAGA AACTAACATG 600

GCTTCCCGCT ATGAAAAGGA ATTCTTGGAG CTCGAAAAAA TTGGAGGTGG GGAATTTGGT 660

ATCGTCTACA AGTGTGTTAA GAGACTGGAT GGATGTATTT ATGCAATAAA GCGCTCTACA 720

AAACCTGTGG GCATGTTGTC AAATGAAAAT ACGCGCTTGC GCGAAGTTTA TGCTCATGCA 780

GTGCTTGGGC AGCACCCCCA TGTAGTACGC TATTACTCCT CCTGGGCAGA AGATGACCGT 840

GTGATCATTC AGAATGAGTA CTGCAATGGT GGAAGCCTGC AAGCTGCTAT ATCTGAAAAC 900

ACGAAGTCTG GTAATCATTT CCAAGAGCCA AAACTCAAAG ACATCCTTCT GCAAATTTCC 960

TTGGGGCTTA AGTACATCCA CAGCTCTGGC CTGGTGCACC TGGACATCAA GCCTAGCAAC 1020

ATCTTTATTT GTCATAACAC ACGAAGTGAT TGTCCTGGAG TCCCAGAAGA GACTGAAAAT 1080

GAAGCTGACT GGTTTCTCTC TGCCAGCGTA ATATATAAAA TTGGTGACCT GGGTCATGTG 1140

ACGTCAATAA AAAAACCCCA AGTGGAAGAA GGAGATATTC GCTTCCTAGC TGATGAGATT 1200

TTTCAAGAGG ATTATCAACA CCTTCCCAAA GGTGATATAT TTGCCCTGGG ATTAACAATT 1260

GCACTGGCAG CTGGAGCCAA TACTTTACCC AGTTGTGGTG AAGACTGGCA CTGGATCCGT 1320

AAGGGTAACT TTCCGGATGT CCCTCAGAAG CTCACAGAAG ATTTTCACAA TTTGCTCAAG 1380

AATATGATCC ACCCTGATCC AAAGGAGAGA CCTTCTGCAG CAGCTCTAGC CAAAAGTCAA 1440

GTTCTCCGGC CCTCCCTGAG CACCACAGAA GAGCTCCAGC GGCAGCTCAT CTTGGAAAAG 1500

TCGAAGATAG CTGCACTGGA AAGGGAACTG AGAAAAATCC AGCAGACCAG GTCCTCCCAG 1560

GGAGACCTCC ACCCTGACAA TCCTGAGGTC TCTGCGGGCC AAACAGAATC AAGAAGTCCA 1620

AAACACCTGG CGAGAAGAAA GAGAGTGAAG TCTTCAAGTT TTATTGATGA ACAATCTTCC 1680

CCATAG 1686

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F e+ekiG Gefg v+k+vkr+dg++yAik+s kp+  ls+e+++lrEv+ahavlgqh++

Q: 208   FLELEKIGGGEFGIVYKCVKRLDGCIYAIKRSTKPVGMLSNENTRLREVYAHAVLGQHPH  267

         7899********************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         vvry+s+W+edd+++iq+E+C+ggsL+aa++e++++ ++++e +lk+ill+++lgl+y+H

Q: 268   VVRYYSSWAEDDRVIIQNEYCNGGSLQAAISENTKSGNHFQEPKLKDILLQISLGLKYIH  327

         ************************************************************

S: 121   ssslvHlDikpenifi.......................tkevtlklgDlGlvtelnsed  157

         ss lvHlDikp+nifi                       +++v++k+gDlG+vt++   +

Q: 328   SSGLVHLDIKPSNIFIchntrsdcpgvpeeteneadwflSASVIYKIGDLGHVTSI---K  384

         ********************************************************...*

S: 158   kskveEGDsrylakEilqeeyskl.kaDiFslgltilevaanvelPsnGeaWhklRkgkl  216

         k++veEGD r+la+Ei+qe+y++l k DiF+lglti+ +a++ +lPs Ge Wh +Rkg++

Q: 385   KPQVEEGDIRFLADEIFQEDYQHLpKGDIFALGLTIALAAGANTLPSCGEDWHWIRKGNF  444

         ************************************************************

S: 217   pdeilkelsedlrellklmlepdperRptaeellkhevl  255

         p ++ ++l+ed+++llk+m++pdp++Rp+a++l+k++vl

Q: 445   P-DVPQKLTEDFHNLLKNMIHPDPKERPSAAALAKSQVL  482

         *.9*******************************99875

Domain Sequence
(FASTA)

FLELEKIGGG EFGIVYKCVK RLDGCIYAIK RSTKPVGMLS NENTRLREVY AHAVLGQHPH 60

VVRYYSSWAE DDRVIIQNEY CNGGSLQAAI SENTKSGNHF QEPKLKDILL QISLGLKYIH 120

SSGLVHLDIK PSNIFICHNT RSDCPGVPEE TENEADWFLS ASVIYKIGDL GHVTSIKKPQ 180

VEEGDIRFLA DEIFQEDYQH LPKGDIFALG LTIALAAGAN TLPSCGEDWH WIRKGNFPDV 240

PQKLTEDFHN LLKNMIHPDP KERPSAAALA KSQVL 275

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007067	; P:mitosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017164	; Wee1-like_protein_kinase.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013