EKS-CAP-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAP-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	526.8	1.1E-158	24	291	268

Status

Unreviewed

Ensembl Protein

ENSCPOP00000019103

UniProt Accession

H0W7Z7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCPOG00000026085	ENSCPOP00000019103	ENSCPOT00000022675

Organism

Cavia porcellus

Functional Description

Protein Length

407

Protein Sequence
(FASTA)

MTLDVGTEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGDEF AVKIMEVTAE 60

RLSPEQLEEV REATRRETQI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT 120

EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDNMQIRLS DFGFSCHLEP 180

GEKLRDLCGT PGYLAPEILK CSMDETHPGY GKEVDLWACG VILFTLLAGS PPFWHRRQIL 240

MLRMIMEGRY QFSSPEWDDR SDTVKDLISR LLQVDPEERL TAEQALQHPF FERCEGSQLW 300

NLTPHQRFRV AVWTVLAAGR VALSARRMRP MTKSALLRDP YALRPVRRLI DNCAFRLYGH 360

WVKKGEQQNR AALFQHQPPG PFPLIGAEEE GDCAPVTEDE CTGAELG 407

Nucleotide Sequence
(FASTA)

ATGACACTGG ACGTGGGGAC GGAGGATGAG CTGCCCGACT GGGCCGCTGC CAAGGAGTTT 60

TACCAGAAGT ATGACCCTAA GGACGTCATT GGCAGAGGAG TGAGCTCTGT GGTCCGCCGT 120

TGCGTTCATC GAGCCACTGG TGATGAGTTT GCAGTGAAGA TCATGGAGGT GACAGCTGAG 180

CGGCTGAGTC CTGAGCAGCT GGAGGAGGTG CGGGAAGCCA CACGGCGAGA GACTCAGATC 240

CTTCGCCAGG TCGCCGGCCA CCCCCACATC ATCACTCTCA TCGATTCGTA CGAGTCTTCT 300

AGCTTCATGT TCCTGGTGTT TGACCTGATG CGGAAGGGAG AGCTGTTTGA CTATCTCACA 360

GAGAAGGTGG CCCTCTCAGA GAAGGAGACC AGGTCCATCA TGAGGTCTCT GCTGGAAGCA 420

GTGAGCTTTC TCCATGCCAA CAACATTGTA CACCGAGACC TGAAGCCTGA GAATATTCTC 480

CTAGATGACA ATATGCAGAT CCGACTCTCA GATTTTGGGT TCTCCTGCCA CTTGGAACCT 540

GGAGAGAAGC TTCGAGATTT GTGTGGGACA CCAGGGTATC TAGCACCAGA GATCCTGAAA 600

TGTTCCATGG ATGAAACCCA CCCAGGATAT GGCAAGGAGG TAGACCTCTG GGCCTGTGGG 660

GTGATCCTCT TCACACTTCT GGCTGGCTCA CCCCCATTCT GGCACCGACG CCAAATCCTG 720

ATGTTACGCA TGATCATGGA GGGCCGGTAC CAGTTCAGTT CACCTGAGTG GGATGACCGT 780

TCTGACACAG TCAAAGACCT GATCTCAAGG CTGCTGCAGG TAGATCCTGA AGAACGCCTG 840

ACAGCTGAGC AGGCCCTCCA GCATCCCTTC TTTGAGCGTT GTGAAGGCAG CCAACTCTGG 900

AACCTTACAC CCCACCAGCG ATTCCGGGTG GCAGTGTGGA CAGTGCTGGC TGCTGGACGA 960

GTGGCCTTAA GTGCCCGCCG TATGCGGCCA ATGACCAAGA GTGCACTGTT GAGGGATCCC 1020

TATGCACTGC GGCCAGTGCG GCGCCTCATT GACAACTGTG CCTTTCGGCT CTATGGGCAC 1080

TGGGTGAAGA AGGGGGAGCA GCAGAATCGA GCAGCCCTCT TCCAGCACCA ACCCCCTGGG 1140

CCTTTTCCTC TCATTGGTGC TGAAGAGGAG GGAGACTGTG CTCCTGTCAC TGAGGATGAG 1200

TGTACAGGTG CTGAGCTTGG A 1221

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pk+++GrGvssvvrrc+++atg+efavki++v+ae+ls+e+++e+reat++e++ilrq

Q: 24    YDPKDVIGRGVSSVVRRCVHRATGDEFAVKIMEVTAERLSPEQLEEVREATRRETQILRQ  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v+Ghp+ii+l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++

Q: 84    VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha+nivhrdlkpenillddn++i+lsdfGfs++le+Geklr+lcGtpgylapeilkcsm

Q: 144   LHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRDLCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++pGy+kevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++

Q: 204   DETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGRYQFSSPEWDDRSDT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+ll+vdpe+rltae+al+hpff

Q: 264   VKDLISRLLQVDPEERLTAEQALQHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKDVIGRG VSSVVRRCVH RATGDEFAVK IMEVTAERLS PEQLEEVREA TRRETQILRQ 60

VAGHPHIITL IDSYESSSFM FLVFDLMRKG ELFDYLTEKV ALSEKETRSI MRSLLEAVSF 120

LHANNIVHRD LKPENILLDD NMQIRLSDFG FSCHLEPGEK LRDLCGTPGY LAPEILKCSM 180

DETHPGYGKE VDLWACGVIL FTLLAGSPPF WHRRQILMLR MIMEGRYQFS SPEWDDRSDT 240

VKDLISRLLQ VDPEERLTAE QALQHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013