EKS-CIS-00085

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00085

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	306.2	1.8E-91	158	410	253

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000000222

UniProt Accession

H2Y4H5;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.10829

Gene Synonyms/Alias

Csa.10829;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000000124	ENSCSAVP00000000225	ENSCSAVT00000000227
ENSCSAVG00000000124	ENSCSAVP00000000226	ENSCSAVT00000000228
ENSCSAVG00000000124	ENSCSAVP00000000219	ENSCSAVT00000000221
ENSCSAVG00000000124	ENSCSAVP00000000218	ENSCSAVT00000000220
ENSCSAVG00000000124	ENSCSAVP00000000221	ENSCSAVT00000000223
ENSCSAVG00000000124	ENSCSAVP00000000222	ENSCSAVT00000000224
ENSCSAVG00000000124	ENSCSAVP00000000223	ENSCSAVT00000000225
ENSCSAVG00000000124	ENSCSAVP00000000224	ENSCSAVT00000000226
ENSCSAVG00000000124	ENSCSAVP00000000220	ENSCSAVT00000000222

Organism

Ciona savignyi

Functional Description

Protein Length

427

Protein Sequence
(FASTA)

MFGGKKKKKP DISGPSNFEH RVHTGFNEDE GKFIGLPIQW QSIIPEVKNR PKPFVDARHI 60

TPVPKIITGR GNKKGVLSNL SAISVTRSNS LRKESPPESR KLNSRRKEAI GPGVSVAPPA 120

AQKALGTNHD SQTITNDEFR AALQMVVCPG DPRESLENFV KIGEGSTGVV CIATQRGTGH 180

HVAVKKMNVR RQQRRELLFN EVVIMRDYHH ENIVDMYSSF LVGDELWVVM EYMEGGALTD 240

LVTRHRLNEP QIATVCVSVL NALAYLHSQG VIHRDIKSDS ILLTKDLTVK LSDFGFCAQI 300

SSDVPKRKSL VGTPYWMAPE VVSRSPYGPE VDIWSLGIMI MEMVDKEPPY FDEAPLHAMR 360

RIRDMPPPKL KHPHKVNPPP HSHLVPIDQI LVRDPSTRST ASELLQHPFL RKSSPHKSIG 420

PITVADR 427

Nucleotide Sequence
(FASTA)

ATGTTTGGTG GTAAAAAGAA GAAGAAACCG GACATTTCTG GTCCCTCTAA CTTCGAGCAT 60

CGTGTCCACA CTGGGTTCAA TGAAGATGAG GGCAAGTTCA TCGGGCTCCC TATTCAATGG 120

CAAAGCATTA TTCCTGAAGT AAAAAATCGT CCCAAGCCAT TCGTTGACGC AAGACACATA 180

ACACCGGTTC CTAAAATCAT CACTGGTAGA GGCAATAAAA AGGGCGTTTT ATCAAATTTA 240

TCGGCTATTT CTGTTACAAG ATCGAATTCG TTAAGGAAAG AGAGCCCACC TGAAAGTCGT 300

AAACTCAACA GTAGAAGGAA GGAGGCGATT GGACCAGGTG TGTCTGTGGC GCCTCCTGCT 360

GCACAGAAAG CACTGGGAAC GAACCACGAC TCGCAAACCA TCACGAACGA CGAGTTTCGA 420

GCTGCTTTGC AAATGGTGGT TTGCCCCGGG GATCCTCGTG AAAGTCTGGA GAACTTCGTG 480

AAGATTGGGG AGGGTTCGAC AGGAGTGGTA TGTATCGCTA CTCAGCGTGG TACTGGCCAT 540

CATGTGGCCG TGAAGAAGAT GAACGTGAGG CGACAGCAGC GGCGGGAACT TTTGTTCAAT 600

GAGGTTGTTA TAATGCGGGA CTACCACCAC GAGAACATAG TGGACATGTA TAGCAGCTTC 660

CTAGTAGGTG ATGAGTTGTG GGTGGTGATG GAATACATGG AGGGGGGAGC TCTCACCGAT 720

CTCGTCACGC GCCATCGACT CAACGAGCCC CAGATCGCCA CCGTGTGTGT ATCCGTGCTC 780

AACGCCCTCG CGTACCTGCA CAGTCAAGGG GTCATTCATA GAGATATTAA AAGTGACTCC 840

ATCTTGCTTA CTAAGGATTT GACAGTGAAA TTATCAGATT TTGGTTTTTG TGCCCAAATA 900

TCGTCCGATG TCCCGAAACG CAAGTCGTTG GTTGGAACTC CATATTGGAT GGCCCCCGAG 960

GTGGTTTCCC GGTCCCCCTA CGGCCCCGAG GTTGATATCT GGTCCCTGGG GATCATGATC 1020

ATGGAGATGG TGGACAAGGA ACCCCCATAT TTCGACGAGG CACCTCTGCA TGCCATGCGA 1080

CGTATACGCG ACATGCCTCC ACCCAAGCTT AAACATCCAC ACAAGGTAAA CCCCCCCCCA 1140

CATTCACACC TGGTTCCTAT TGATCAGATC CTGGTCCGCG ACCCGAGCAC CCGATCCACC 1200

GCATCCGAAC TCCTCCAACA CCCATTCCTT CGCAAATCCT CTCCTCACAA ATCCATCGGG 1260

CCAATCACCG TGGCCGACCG GTAG 1284

Domain Profile

S: 3     lleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyl  62

          + +ig+G++g v++a+++ tg+ va+kk+n+++q++ e+l++e+ ++++++h+niv+++

Q: 158   NFVKIGEGSTGVVCIATQRGTGHHVAVKKMNVRRQQRRELLFNEVVIMRDYHHENIVDMY  217

         5679********************************************************

S: 63    esflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHr  122

         +sfl+ +elw+vmey++gG+l+dlv+   +++l+E qia+++ +vl+aL+ylHs++viHr

Q: 218   SSFLVGDELWVVMEYMEGGALTDLVT---RHRLNEPQIATVCVSVLNALAYLHSQGVIHR  274

         **************************...9******************************

S: 123   dikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaD  182

         dik+++iLlt++ +VkLsdfg++aq+++++ krk++vgtpywmAPEv++  ++ Y  ++D

Q: 275   DIKSDSILLTKDLTVKLSDFGFCAQISSDVPKRKSLVGTPYWMAPEVVS--RSPYGPEVD  332

         *************************************************..9********

S: 183   iwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkef...vekclq  239

         iwslGI+++e+++ epP++d+ pl+a+ +i + +ppklk+++k+ +  ++    ++++l

Q: 333   IWSLGIMIMEMVDKEPPYFDEAPLHAMRRIRDMPPPKLKHPHKVNPPPHSHlvpIDQILV  392

         *******************************************9988776524469****

S: 240   knpekRpsasellkhkFl  257

         ++p++R++asell+h+Fl

Q: 393   RDPSTRSTASELLQHPFL  410

         *****************7

Domain Sequence
(FASTA)

NFVKIGEGST GVVCIATQRG TGHHVAVKKM NVRRQQRREL LFNEVVIMRD YHHENIVDMY 60

SSFLVGDELW VVMEYMEGGA LTDLVTRHRL NEPQIATVCV SVLNALAYLH SQGVIHRDIK 120

SDSILLTKDL TVKLSDFGFC AQISSDVPKR KSLVGTPYWM APEVVSRSPY GPEVDIWSLG 180

IMIMEMVDKE PPYFDEAPLH AMRRIRDMPP PKLKHPHKVN PPPHSHLVPI DQILVRDPST 240

RSTASELLQH PFL 253

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013