EKS-CIS-00193

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00193

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	448.7	5.8E-135	341	598	258

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000000348

UniProt Accession

H2Y4U7;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000000192	ENSCSAVP00000000350	ENSCSAVT00000000353
ENSCSAVG00000000192	ENSCSAVP00000000346	ENSCSAVT00000000349
ENSCSAVG00000000192	ENSCSAVP00000000347	ENSCSAVT00000000350
ENSCSAVG00000000192	ENSCSAVP00000000348	ENSCSAVT00000000351
ENSCSAVG00000000192	ENSCSAVP00000000349	ENSCSAVT00000000352
ENSCSAVG00000000192	ENSCSAVP00000000343	ENSCSAVT00000000346
ENSCSAVG00000000192	ENSCSAVP00000000344	ENSCSAVT00000000347
ENSCSAVG00000000192	ENSCSAVP00000000345	ENSCSAVT00000000348

Organism

Ciona savignyi

Functional Description

Protein Length

626

Protein Sequence
(FASTA)

DEQMHEIEIK ENTIKGCQKA DPSQFELLKV LGQGSFGKVF LVRKIVGNDR GQLYAMKVLK 60

KAKLKVRDRV RTKMERNILV DVNHPFIVKV YYAFQTDGNL YMVLAYLRGG DLFTRLSKEL 120

MFTEDDVKIY LAELALSLDH LHSLGIIYRD LKPENILLDV DGHIALTDFG LSKESTEGSE 180

KAYSFCGTVE YMAPEVVNRR GHDQSADWWS FGVLMYEMLT GQLPFQGRDR KDTMTQILKA 240

KLGMPQFLSQ EAQRYNMFDI DPPFKPSVTR AEDAAYFDSE FTSRTPRDSP GVPASAAAQQ 300

LFRGFSFVAP IIEEEAHVGA PQDEFMTSQL NQSPKKFHDE YEEKEEIGIG SYSVCKRCIH 360

KGTKKEYAVK IIFKNKRDCE EEVHILLRYG QHPNIITLKD VFDDGQHVFL VTELMKGGEL 420

LDKILRQKFF TEKEASAVLK TVTKVVVYMH KNGVVHRDLK PSNILYADET GNPDSLRVCD 480

FGFAKQLRHD NGLLMTPCYT ANFVAPEVLK KKGYDEACDI WSLGVLLYTM LAGYTPFANG 540

PDDTPTDILK RIETGKFNMS GGNWKSVSDI AKDLVRRMLH VDPNRRLSAP QVLMHPFIAR 600

PDQLPEFHLN QSKDYKFVKG AMSAMF 626

Nucleotide Sequence
(FASTA)

GATGAGCAAA TGCATGAAAT TGAAATCAAA GAAAATACGA TTAAGGGTTG TCAAAAAGCT 60

GACCCAAGTC AGTTTGAACT GCTTAAGGTT TTGGGTCAAG GGTCTTTTGG GAAGGTCTTT 120

CTCGTCCGTA AAATCGTCGG CAACGACCGT GGTCAGCTGT ATGCTATGAA AGTACTGAAG 180

AAAGCCAAAT TGAAAGTTCG TGACAGGGTA AGGACAAAAA TGGAGAGGAA CATATTGGTC 240

GACGTGAATC ATCCTTTTAT AGTCAAGGTG TATTACGCTT TTCAAACCGA CGGGAATCTC 300

TACATGGTGC TGGCGTATTT GCGTGGGGGT GATCTGTTTA CTCGTCTTTC CAAAGAGCTC 360

ATGTTCACAG AGGATGACGT GAAGATCTAT CTCGCCGAGT TGGCTCTCTC ACTCGACCAT 420

CTTCATTCAC TTGGGATCAT CTATCGGGAT TTGAAGCCGG AAAACATCCT GCTTGACGTG 480

GATGGGCACA TTGCTCTTAC TGACTTCGGG TTAAGCAAGG AGTCGACAGA AGGCTCGGAG 540

AAGGCGTATT CATTCTGTGG CACCGTGGAG TACATGGCAC CAGAGGTTGT CAACCGACGT 600

GGTCACGACC AGTCCGCTGA CTGGTGGTCG TTTGGGGTTC TAATGTATGA GATGCTGACT 660

GGACAGCTGC CTTTTCAAGG ACGAGATAGA AAGGACACAA TGACCCAAAT TTTAAAGGCG 720

AAACTAGGAA TGCCTCAATT CTTGAGCCAA GAAGCACAAA GATATAATAT GTTTGACATC 780

GACCCCCCAT TCAAACCATC GGTCACCCGG GCCGAGGACG CTGCTTACTT CGATTCGGAA 840

TTCACCTCAA GAACTCCGAG AGATTCTCCT GGGGTCCCAG CCAGTGCGGC GGCTCAACAA 900

TTATTCCGGG GCTTCTCGTT CGTGGCCCCC ATCATTGAGG AGGAGGCCCA CGTGGGTGCC 960

CCGCAGGACG AATTTATGAC ATCACAGTTG AATCAATCGC CGAAGAAATT CCATGATGAG 1020

TACGAAGAGA AGGAAGAGAT CGGAATTGGA TCGTATTCGG TTTGCAAGCG ATGCATTCAC 1080

AAAGGCACCA AGAAAGAATA TGCAGTCAAG ATCATCTTCA AGAACAAGAG AGATTGTGAG 1140

GAAGAGGTTC ATATCTTGCT TCGTTATGGA CAACATCCCA ACATCATCAC ACTCAAGGAT 1200

GTATTTGACG ACGGACAGCA CGTCTTCCTC GTCACTGAGC TGATGAAGGG GGGTGAGCTG 1260

TTGGACAAGA TCCTCCGGCA GAAGTTCTTC ACTGAGAAGG AAGCGAGCGC GGTGCTCAAG 1320

ACGGTCACCA AAGTGGTCGT CTACATGCAC AAGAATGGGG TCGTACACCG CGATTTGAAA 1380

CCGAGCAACA TACTGTACGC CGATGAGACA GGAAATCCCG ACTCGCTACG AGTTTGCGAC 1440

TTCGGCTTCG CTAAACAACT TCGTCATGAC AACGGGTTGC TGATGACCCC GTGCTACACA 1500

GCTAACTTTG TTGCGCCGGA GGTGTTGAAA AAGAAGGGTT ACGACGAGGC TTGCGACATC 1560

TGGAGCTTAG GGGTCTTGCT GTACACGATG CTGGCTGGGT ACACCCCGTT CGCGAACGGT 1620

CCCGACGACA CACCCACCGA TATCTTGAAG AGAATCGAAA CTGGAAAGTT CAACATGTCG 1680

GGAGGAAACT GGAAGAGTGT GTCGGATATC GCAAAGGATC TAGTTCGTCG TATGCTGCAC 1740

GTCGACCCGA ATCGTCGATT GTCAGCCCCG CAGGTCCTCA TGCACCCTTT CATAGCTCGG 1800

CCCGATCAAC TGCCCGAGTT TCATCTCAAC CAGTCCAAGG ATTACAAGTT CGTCAAGGGG 1860

GCGATGTCTG CCATGTTC 1878

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         ye ke++G Gsysvckrc+hk t++e+avkii k+krd +ee++illry+qhpni+tlkd

Q: 341   YEEKEEIGIGSYSVCKRCIHKGTKKEYAVKIIFKNKRDCEEEVHILLRYGQHPNIITLKD  400

         6789********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         v+ddg++v+lv+el+kGGelld+i+++kff+e+easa+l+t++k v y+h++Gvvhrdlk

Q: 401   VFDDGQHVFLVTELMKGGELLDKILRQKFFTEKEASAVLKTVTKVVVYMHKNGVVHRDLK  460

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nily+de++n++s++++dfGfak++r++ngll+tpcyt+nfvapevlk++Gydeacd+

Q: 461   PSNILYADETGNPDSLRVCDFGFAKQLRHDNGLLMTPCYTANFVAPEVLKKKGYDEACDI  520

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslGvllytmlaGy+pfangp+dt+++il++i+ Gkf +sG++w+svs+ akdlv+++l+

Q: 521   WSLGVLLYTMLAGYTPFANGPDDTPTDILKRIETGKFNMSGGNWKSVSDIAKDLVRRMLH  580

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         vdp++rl + q+l h+++

Q: 581   VDPNRRLSAPQVLMHPFI  598

         **************9986

Domain Sequence
(FASTA)

YEEKEEIGIG SYSVCKRCIH KGTKKEYAVK IIFKNKRDCE EEVHILLRYG QHPNIITLKD 60

VFDDGQHVFL VTELMKGGEL LDKILRQKFF TEKEASAVLK TVTKVVVYMH KNGVVHRDLK 120

PSNILYADET GNPDSLRVCD FGFAKQLRHD NGLLMTPCYT ANFVAPEVLK KKGYDEACDI 180

WSLGVLLYTM LAGYTPFANG PDDTPTDILK RIETGKFNMS GGNWKSVSDI AKDLVRRMLH 240

VDPNRRLSAP QVLMHPFI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016239	; Ribosomal_S6_kinase_II.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 2.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013