EKS-CIS-00175

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00175

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	422.1	9.5E-127	145	396	252

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000000698

UniProt Accession

H2Y5V0;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.9294

Gene Synonyms/Alias

Csa.9294;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000000391	ENSCSAVP00000000698	ENSCSAVT00000000705
ENSCSAVG00000000391	ENSCSAVP00000000697	ENSCSAVT00000000704

Organism

Ciona savignyi

Functional Description

Protein Length

470

Protein Sequence
(FASTA)

SKDQYSETKK RYTVYKVQVN IGQDTWFVFR RYTEFDKLYN SLKKQFPHIV WKLPSKRIFG 60

NNFDPQFIRQ RRDGLNDFIN TIVSNLDVLQ FPDSRAFLAL DNPRNRLSND SDDGESPQQK 120

VVIERNEPDM NLGPSADPHA CPGDFDYLKV IGKGSFGKVL LATHRKNGKF YAVKETILHC 180

YLIVTQQKHI MAERNVLLQN LKHPFLVGLH YSFQTTDKLY FVLDYVNGGE LFFHLQRERT 240

FTESRSRFYA AEIASAVGYM HSLEIIYRDL KPENILLDSE GHVILTDFGL CKEGIKTNQT 300

TTTFSPEVLK KQPYTKAVDW WCLGAVLYEM LYGLPPFYSR DTHEMYENIL YKPLKLRPTV 360

SSAARNILEL LLQKKPQLRL GSGEKDLNEI KEHAFFASLN WVELESKRIQ PPYNPNVAGP 420

EDLKHVDPEF VREPVSRSIR GSDKVMASVS EVDDAFIGFS YAPPAEDTFL 470

Nucleotide Sequence
(FASTA)

TCGAAAGATC AATATTCGGA GACGAAGAAG AGATACACGG TATACAAAGT CCAAGTCAAT 60

ATCGGACAGG ATACTTGGTT CGTGTTTAGA AGATACACAG AGTTTGATAA GCTGTATAAT 120

TCGCTGAAGA AACAATTCCC GCACATTGTA TGGAAACTTC CATCGAAACG AATCTTCGGA 180

AACAACTTTG ATCCCCAGTT CATCAGGCAA CGTAGGGATG GCCTCAATGA CTTCATAAAC 240

ACCATTGTCT CAAATCTAGA TGTGCTGCAA TTCCCCGACA GCAGAGCATT CCTCGCGCTC 300

GACAATCCAC GGAATCGACT CAGCAACGAT AGCGATGATG GGGAATCCCC ACAACAAAAG 360

GTGGTGATTG AACGTAACGA ACCCGACATG AACCTTGGTC CTTCTGCTGA TCCACATGCG 420

TGTCCCGGTG ACTTTGATTA CTTGAAAGTG ATCGGGAAAG GAAGCTTCGG GAAGGTACTT 480

CTCGCCACTC ATAGGAAAAA TGGAAAGTTT TACGCCGTAA AGGAAACAAT CCTTCATTGT 540

TACCTCATTG TGACGCAGCA AAAACACATA ATGGCGGAAC GCAACGTGCT GCTGCAGAAC 600

CTCAAGCATC CATTCCTGGT GGGACTCCAT TATAGCTTCC AAACCACCGA CAAGTTGTAC 660

TTCGTGCTCG ACTACGTGAA TGGGGGAGAA CTCTTCTTTC ATCTGCAGCG AGAGAGGACG 720

TTCACTGAAT CAAGGTCTCG GTTCTACGCA GCAGAAATAG CGTCAGCGGT CGGCTATATG 780

CACAGTCTCG AGATCATCTA TAGAGATCTT AAACCCGAAA ATATTCTTCT TGATTCCGAG 840

GGTCATGTGA TCCTCACCGA CTTCGGGTTA TGCAAGGAAG GAATCAAGAC CAACCAGACC 900

ACCACCACCT TCTCACCAGA AGTGTTGAAG AAGCAGCCGT ACACCAAAGC AGTGGATTGG 960

TGGTGTCTTG GCGCGGTGTT GTACGAGATG TTGTACGGAT TGCCACCATT TTATAGTCGC 1020

GACACCCACG AAATGTACGA GAATATTTTG TACAAACCTC TGAAGTTACG ACCGACCGTG 1080

TCATCTGCTG CTAGGAATAT TCTAGAACTG CTCTTACAAA AGAAGCCACA GCTGCGATTG 1140

GGATCCGGGG AAAAAGATTT GAACGAAATC AAGGAACACG CTTTCTTTGC TTCTCTCAAC 1200

TGGGTGGAGC TAGAGAGCAA GAGGATCCAA CCTCCGTACA ATCCTAATGT CGCTGGACCA 1260

GAAGATTTGA AGCATGTTGA TCCTGAGTTT GTGAGGGAAC CGGTATCCCG ATCTATCAGG 1320

GGGTCGGACA AGGTGATGGC CAGTGTGTCA GAAGTGGACG ACGCATTTAT CGGATTCTCC 1380

TATGCCCCTC CTGCCGAGGA CACCTTCCTC 1410

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fd+lkvigkgsfgkvlla +++++kfyavk    +  l   ++khimaernvll+n+khp

Q: 145   FDYLKVIGKGSFGKVLLATHRKNGKFYAVKETILHCYLIVTQQKHIMAERNVLLQNLKHP  204

         9*****************************888888888899******************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt++klyfvldyvnggelffhlqrer+f+e+r+rfyaaeiasa+gy+hsl+

Q: 205   FLVGLHYSFQTTDKLYFVLDYVNGGELFFHLQRERTFTESRSRFYAAEIASAVGYMHSLE  264

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenillds+ghv+ltdfglcke+i++++tt+tf       +pevl+k+py ++

Q: 265   IIYRDLKPENILLDSEGHVILTDFGLCKEGIKTNQTTTTF-------SPEVLKKQPYTKA  317

         ***************************************9.......69***********

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysrd+ emy+nil kpl+l+p++s aa+++le ll+k+ +

Q: 318   VDWWCLGAVLYEMLYGLPPFYSRDTHEMYENILYKPLKLRPTVSSAARNILELLLQKKPQ  377

         ************************************************************

S: 241   krlga.kedfleiknhvff  258

          rlg+ ++d+ eik+h ff

Q: 378   LRLGSgEKDLNEIKEHAFF  396

         ****83569*********9

Domain Sequence
(FASTA)

FDYLKVIGKG SFGKVLLATH RKNGKFYAVK ETILHCYLIV TQQKHIMAER NVLLQNLKHP 60

FLVGLHYSFQ TTDKLYFVLD YVNGGELFFH LQRERTFTES RSRFYAAEIA SAVGYMHSLE 120

IIYRDLKPEN ILLDSEGHVI LTDFGLCKEG IKTNQTTTTF SPEVLKKQPY TKAVDWWCLG 180

AVLYEMLYGL PPFYSRDTHE MYENILYKPL KLRPTVSSAA RNILELLLQK KPQLRLGSGE 240

KDLNEIKEHA FF 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013