EKS-CIS-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	409.8	4.6E-123	25	278	254

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000002305

UniProt Accession

H2YAF8;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.5715

Gene Synonyms/Alias

Csa.5715;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000001349	ENSCSAVP00000002306	ENSCSAVT00000002344
ENSCSAVG00000001349	ENSCSAVP00000002305	ENSCSAVT00000002343

Organism

Ciona savignyi

Functional Description

Protein Length

568

Protein Sequence
(FASTA)

KMSRKDIPIK EIPETLFDSS TGKRYQRGRF LGKGGFAKCY EITDMDSPGK IFAGKIVPKA 60

LLVKPHQKDK MAQEISLHRS VSHEHVVGFY GFFEDDNFVY VVLELCRRRS LMELHKRRKA 120

LTEPEARYYM RQIILGMQYL HGKKIIHRDL KLGNLFLTDE MEIKIGDLGL ATHVDFDGER 180

KKTLCGTPNY IAPEVLGKKG HSYEVDIWSL GCIMYTLLIG KPPFETTSLK ETYTRIKKNE 240

YRIPPSISPI ARNLITKMLR NDPQSRPSVH GLLQDDFFTG GYLPPRLPTT CLSMAPRFTP 300

ALLNSAQRKP LHDINNEIPH CLLTAGAVNA SAAPAKCEPP SQHDVESPDF HMDDLMKQLT 360

ALIDSNPSQR RLIEMAEDPA ANPVLWISKW VDYTDKYGLG YQLCDNSNGV LFNDCTRLLL 420

YNNDEQIEYI DKEMAESYHT LKAYPESLTK KVTLLKYFRN YMSEHLLKAG AGMAPKEGDQ 480

FSRLPFLRTW FRTRSAIILH LSNGTLQINF FNDHTKIILC PLMGAVTYID ASKKFCTYRL 540

TQLQNHGCCR ELAHRVRYAR TMLEKLIT 568

Nucleotide Sequence
(FASTA)

AAAATGTCTC GCAAAGACAT CCCGATTAAA GAAATTCCTG AAACATTATT TGATAGTTCA 60

ACCGGCAAAA GATACCAGCG AGGCCGTTTC CTTGGCAAAG GAGGTTTTGC AAAATGTTAT 120

GAAATAACCG ATATGGACTC GCCTGGAAAA ATATTTGCTG GAAAAATAGT GCCAAAGGCA 180

CTCCTTGTAA AGCCACACCA GAAAGATAAG ATGGCACAAG AAATTTCTTT GCACAGAAGT 240

GTATCACATG AACATGTTGT TGGCTTTTAT GGATTTTTTG AAGATGACAA TTTTGTTTAT 300

GTTGTTCTTG AACTATGCAG AAGAAGGTCA CTTATGGAGT TGCATAAGAG GAGAAAAGCT 360

CTGACTGAGC CGGAAGCTCG CTACTATATG AGGCAGATTA TTCTAGGAAT GCAGTACTTG 420

CATGGGAAAA AGATTATTCA TCGCGACTTA AAGCTGGGAA ACTTATTCCT CACTGATGAA 480

ATGGAAATCA AAATTGGCGA TCTTGGTCTC GCAACTCATG TTGATTTCGA CGGAGAACGG 540

AAGAAAACCT TGTGCGGAAC ACCAAACTAC ATTGCCCCTG AGGTGCTTGG GAAAAAAGGA 600

CACAGTTACG AAGTGGATAT TTGGTCATTA GGATGTATTA TGTATACCCT TCTGATTGGT 660

AAGCCTCCGT TTGAAACCAC TTCACTGAAG GAAACTTACA CACGAATTAA GAAGAATGAA 720

TACAGAATCC CACCATCTAT TTCCCCTATT GCCAGAAATC TTATCACAAA AATGTTACGG 780

AACGACCCGC AGTCGAGACC ATCAGTCCAC GGGTTGCTAC AAGATGATTT CTTCACGGGT 840

GGCTACCTCC CTCCCCGATT GCCGACCACT TGTTTGTCCA TGGCTCCTCG CTTCACTCCA 900

GCTCTCCTGA ACTCTGCCCA GCGGAAACCA CTGCACGATA TTAATAATGA AATTCCACAT 960

TGTTTATTAA CAGCGGGCGC TGTGAATGCT TCGGCGGCAC CAGCCAAGTG TGAACCACCC 1020

TCACAACACG ATGTAGAGTC ACCTGATTTC CATATGGATG ATTTGATGAA ACAGTTGACG 1080

GCTCTTATTG ATTCGAACCC ATCTCAAAGA AGACTCATCG AAATGGCAGA AGATCCTGCT 1140

GCAAATCCTG TTTTGTGGAT CAGCAAATGG GTCGATTACA CCGATAAATA TGGCTTGGGC 1200

TACCAGCTAT GTGATAACAG CAACGGTGTT TTATTCAACG ACTGCACGCG CCTACTGCTC 1260

TACAACAACG ATGAACAGAT TGAATACATT GACAAAGAAA TGGCAGAGTC TTACCACACA 1320

TTGAAAGCCT ACCCTGAGTC TCTGACTAAG AAAGTCACTT TACTCAAATA CTTCAGGAAT 1380

TACATGTCAG AGCATCTGCT GAAGGCTGGA GCAGGCATGG CTCCCAAGGA AGGTGATCAA 1440

TTCTCCCGAT TGCCGTTCCT GCGGACATGG TTCCGTACAC GAAGCGCCAT CATCCTACAC 1500

CTCAGCAATG GAACGTTGCA GATCAATTTC TTCAATGACC ACACCAAGAT CATCCTATGT 1560

CCACTGATGG GGGCAGTGAC CTACATCGAC GCCTCCAAGA AGTTCTGCAC TTACCGTCTC 1620

ACGCAGCTGC AGAACCACGG ATGTTGTCGC GAATTGGCGC ACCGAGTCCG CTATGCACGC 1680

ACCATGCTCG AAAAGCTGAT CACC 1704

Domain Profile

S: 1     yergkllGkGgfakcyelkdlet.kevfavkvvpksllakekqrekvekeieihrslkhk  59

         y+rg++lGkGgfakcye++d+++ +++fa k+vpk+ll+k++q++k+++ei++hrs++h+

Q: 25    YQRGRFLGKGGFAKCYEITDMDSpGKIFAGKIVPKALLVKPHQKDKMAQEISLHRSVSHE  84

         99*******************974799*********************************

S: 60    nivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekr  119

         ++v +y ffed+++vy+vlelc+rrsl+el+krrkaltepe+ryy+rqi+ g++ylh k+

Q: 85    HVVGFYGFFEDDNFVYVVLELCRRRSLMELHKRRKALTEPEARYYMRQIILGMQYLHGKK  144

         ************************************************************

S: 120   ilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghsle  179

         i+hrdlklgnlfl++e+e+kigd+Glat+++ ++erkktlcGtPnyiaPevl kkghs+e

Q: 145   IIHRDLKLGNLFLTDEMEIKIGDLGLATHVDFDGERKKTLCGTPNYIAPEVLGKKGHSYE  204

         ************************************************************

S: 180   vdiWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePe  239

         vdiWslGci+ytll+GkPPfet++lkety++ikk+ey++P s+s+ a++li+k+l+++P+

Q: 205   VDIWSLGCIMYTLLIGKPPFETTSLKETYTRIKKNEYRIPPSISPIARNLITKMLRNDPQ  264

         ************************************************************

S: 240   erpsleevlkdefl  253

         +rps++ +l+d+f+

Q: 265   SRPSVHGLLQDDFF  278

         *************8

Domain Sequence
(FASTA)

YQRGRFLGKG GFAKCYEITD MDSPGKIFAG KIVPKALLVK PHQKDKMAQE ISLHRSVSHE 60

HVVGFYGFFE DDNFVYVVLE LCRRRSLMEL HKRRKALTEP EARYYMRQII LGMQYLHGKK 120

IIHRDLKLGN LFLTDEMEIK IGDLGLATHV DFDGERKKTL CGTPNYIAPE VLGKKGHSYE 180

VDIWSLGCIM YTLLIGKPPF ETTSLKETYT RIKKNEYRIP PSISPIARNL ITKMLRNDPQ 240

SRPSVHGLLQ DDFF 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013