EKS-CIS-00007

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00007

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	430.2	2.9E-129	22	287	266

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000002835

UniProt Accession

H2YBY7;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000001691	ENSCSAVP00000002835	ENSCSAVT00000002879

Organism

Ciona savignyi

Functional Description

Protein Length

417

Protein Sequence
(FASTA)

MVSAKTEELP DVNTAREFYS KYEPKEILGR GVSSCVRRCV EKKTSKDFAV KIIDLTDGNN 60

QISEELRLVT RNEINILKEV SGHAHIIELV DVFETSTFIF LIFELLKRGE LFDYLTEVVK 120

FSERQTRSTM RSLLEAISYL HSQNIIHRDL KPENILLDDD LQLHLSDFGF STKIEKGQHF 180

TELYGTPGYM SPEMLQCTVD ENHRGYGKEI DMWACGVIMY TLLAGAPPFW HRRQMIMLRR 240

IMEGQYSFPS PDWDDISTSA RDLVSRMMEV DPTKRLTAKM ALAHPFFQQV EDTSRYSSKP 300

FNPRRKFRVA VYTIVAYRRI MAQMHQHRPL KLAVAARDPY SVKALRRIID ASAFRVYGHW 360

IKKAANQNRA TLFENSSRAD QRKLEELEEF AAGMHDDGLL MSLVPSSGNS FIAQPVS 417

Nucleotide Sequence
(FASTA)

ATGGTTAGTG CAAAGACGGA AGAACTGCCC GACGTTAACA CGGCGCGTGA ATTTTACAGC 60

AAATATGAAC CCAAAGAAAT CTTAGGAAGG GGGGTCAGTA GTTGTGTACG TCGGTGTGTT 120

GAGAAGAAAA CGTCAAAGGA TTTCGCTGTA AAGATTATAG ACTTAACCGA TGGCAACAAT 180

CAAATAAGCG AGGAATTAAG ACTCGTCACG CGGAACGAGA TTAACATTCT TAAAGAAGTA 240

TCTGGACATG CTCATATAAT TGAGTTGGTT GATGTGTTCG AAACCAGCAC CTTCATATTT 300

CTAATCTTTG AATTGTTAAA ACGTGGAGAA CTTTTTGATT ACCTCACTGA AGTTGTCAAG 360

TTCAGCGAAC GGCAAACAAG ATCTACAATG CGGTCTCTTT TAGAAGCGAT CTCCTACTTA 420

CACAGTCAGA ATATTATTCA CCGTGACCTC AAGCCTGAGA ATATTCTTCT GGATGATGAC 480

CTACAATTGC ATTTGTCCGA TTTCGGGTTT TCAACAAAGA TAGAAAAAGG CCAACACTTT 540

ACAGAGTTGT ACGGCACACC AGGCTACATG TCCCCCGAGA TGCTGCAATG CACAGTGGAT 600

GAGAACCACA GGGGATATGG GAAGGAGATC GACATGTGGG CGTGTGGTGT CATCATGTAC 660

ACACTGTTAG CTGGTGCTCC TCCCTTCTGG CACCGCCGTC AGATGATAAT GCTACGGAGG 720

ATAATGGAAG GTCAATACTC ATTCCCCAGT CCTGACTGGG ATGATATCTC CACCTCAGCA 780

CGAGATTTGG TTTCTCGTAT GATGGAAGTT GACCCCACCA AACGACTGAC AGCCAAAATG 840

GCGTTGGCTC ATCCATTCTT CCAACAAGTA GAAGACACTT CAAGATATTC GTCCAAACCG 900

TTCAACCCAA GACGCAAGTT CAGGGTGGCA GTCTACACGA TCGTGGCGTA CCGCCGCATA 960

ATGGCGCAGA TGCACCAGCA CCGTCCTCTC AAGCTCGCAG TCGCCGCGCG AGACCCATAC 1020

TCAGTAAAAG CCCTTCGCCG CATAATAGAC GCGTCGGCCT TCAGAGTATA CGGGCACTGG 1080

ATCAAAAAAG CCGCCAACCA AAACCGCGCC ACACTCTTCG AGAACAGCTC GCGCGCGGAC 1140

CAGCGCAAGT TGGAAGAACT GGAAGAGTTC GCCGCTGGTA TGCATGACGA CGGACTCCTT 1200

ATGTCGCTCG TACCTTCATC AGGGAACAGT TTCATCGCAC AACCTGTATC T 1251

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         yepkeilGrGvss vrrc+ek+t+++favkiid++ ++      +elr  t++e++il++

Q: 22    YEPKEILGRGVSSCVRRCVEKKTSKDFAVKIIDLTDGNNQ--ISEELRLVTRNEINILKE  79

         9*********************************955433..34578889**********

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         vsGh +ii+l dv+e+s+f+fl+f+l+k+Gelfdylte+v +se++tr+ mr+llea++y

Q: 80    VSGHAHIIELVDVFETSTFIFLIFELLKRGELFDYLTEVVKFSERQTRSTMRSLLEAISY  139

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh++ni+hrdlkpenilldd+ +++lsdfGfst++e+G++++el Gtpgy++pe+l+c++

Q: 140   LHSQNIIHRDLKPENILLDDDLQLHLSDFGFSTKIEKGQHFTELYGTPGYMSPEMLQCTV  199

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++ Gy+ke+d+wa+Gvi+ytllaG+ppfwhr+q++mlr imeG+y+f sp+wddis +

Q: 200   DENHRGYGKEIDMWACGVIMYTLLAGAPPFWHRRQMIMLRRIMEGQYSFPSPDWDDISTS  259

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         ++dl+s+++ vdp+krlta+ alahpff

Q: 260   ARDLVSRMMEVDPTKRLTAKMALAHPFF  287

         ***************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSCVRRCVE KKTSKDFAVK IIDLTDGNNQ ISEELRLVTR NEINILKEVS 60

GHAHIIELVD VFETSTFIFL IFELLKRGEL FDYLTEVVKF SERQTRSTMR SLLEAISYLH 120

SQNIIHRDLK PENILLDDDL QLHLSDFGFS TKIEKGQHFT ELYGTPGYMS PEMLQCTVDE 180

NHRGYGKEID MWACGVIMYT LLAGAPPFWH RRQMIMLRRI MEGQYSFPSP DWDDISTSAR 240

DLVSRMMEVD PTKRLTAKMA LAHPFF 266

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013