EKS-CIS-00044

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00044

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	415.2	1.3E-124	203	489	287

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000003194

UniProt Accession

H2YCZ6;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000001900	ENSCSAVP00000003195	ENSCSAVT00000003244
ENSCSAVG00000001900	ENSCSAVP00000003194	ENSCSAVT00000003243
ENSCSAVG00000001900	ENSCSAVP00000003196	ENSCSAVT00000003245

Organism

Ciona savignyi

Functional Description

Protein Length

502

Protein Sequence
(FASTA)

MKNLVSVILL SCCLVQFASA LTCYCGGSRE NPNCELGIDN CTVASGICFT LTEILPESKT 60

LLVQRGCMET QQVVPYRRPF MCEPLAGSTI QAHCCSKDFC NHPDTNVAPT IQTPAGPVTK 120

DKLPITLIVL ISVGFCLIVG LIVIAAVFFK KRSAKSGSPL VPGSNSSDSN LPGPYLHHED 180

ELSLSGSGAG LPLLVHRTIA RQIQLQDVIG KGRYGEVFRG KWRGEDVAVK KFVTRDESSW 240

AREAEIYQTI MLRHENILGF IAADNKDVGT WTELWLVSEY HENGSLFDYL GETRIDVASM 300

LKIVGSIASG LAHLHNEIVG TLGKPPIAHC DLKSKNILVK KNGECAIADL GLAVRHDSST 360

DTIDIPPNNR VGTKRYMAPE ILDETLNMLH FDSFKRADIY SLGLVFWEVV RRCNIGGQNL 420

DYQLPYFDMV PDDPSIEQMR TIVCEKNIRP QKETTWHKYD TTERMWRLMQ ECWYENGCAR 480

LTALRVKKSI ARIEDEEGVK HV 502

Nucleotide Sequence
(FASTA)

ATGAAGAATT TGGTGTCTGT GATATTGTTG TCATGCTGTT TGGTTCAATT TGCCTCAGCT 60

CTAACTTGCT ACTGTGGTGG GTCAAGGGAA AATCCGAACT GTGAACTCGG AATTGACAAT 120

TGTACTGTCG CTAGCGGAAT TTGCTTTACT CTTACCGAAA TACTACCCGA ATCAAAAACA 180

CTACTGGTTC AACGTGGTTG TATGGAAACC CAACAAGTGG TTCCATACCG TCGTCCCTTC 240

ATGTGTGAAC CCTTGGCTGG CTCCACTATC CAGGCACATT GCTGTTCCAA GGATTTCTGC 300

AACCATCCTG ACACAAACGT CGCACCCACC ATCCAAACAC CTGCAGGCCC AGTTACAAAA 360

GATAAACTAC CAATAACACT GATTGTGCTT ATATCAGTTG GTTTCTGCCT GATAGTTGGG 420

TTGATTGTCA TAGCAGCCGT GTTCTTCAAG AAGAGATCGG CCAAATCCGG GAGTCCACTT 480

GTACCTGGGT CTAACTCAAG CGATAGCAAC CTACCAGGTC CGTACCTTCA TCATGAAGAT 540

GAACTCTCTC TCAGCGGATC GGGTGCAGGG CTCCCTCTAC TGGTGCATCG GACAATAGCT 600

CGGCAGATCC AACTTCAAGA TGTTATTGGG AAGGGAAGAT ACGGTGAAGT GTTTCGAGGG 660

AAATGGAGAG GGGAGGATGT TGCCGTGAAG AAGTTCGTCA CTCGTGATGA GAGCTCGTGG 720

GCAAGAGAGG CCGAGATCTA TCAAACCATC ATGTTGCGAC ACGAGAATAT ACTCGGATTC 780

ATTGCAGCTG ATAACAAAGA TGTTGGCACA TGGACAGAGT TGTGGTTGGT GTCGGAATAT 840

CACGAGAACG GATCGTTGTT CGATTACCTC GGTGAAACAC GGATAGACGT GGCGTCTATG 900

CTCAAGATAG TTGGTTCCAT CGCGAGTGGG CTTGCTCATT TGCATAACGA GATTGTCGGT 960

ACTTTAGGGA AACCCCCCAT TGCTCATTGC GACCTGAAAT CGAAGAACAT CCTGGTGAAG 1020

AAGAACGGGG AATGCGCGAT CGCTGATCTC GGGTTGGCAG TCCGCCACGA TTCCAGCACC 1080

GACACCATCG ACATTCCACC CAATAACAGG GTGGGGACTA AAAGGTACAT GGCTCCGGAG 1140

ATACTAGATG AAACACTGAA CATGCTTCAC TTTGATTCAT TCAAACGAGC TGATATTTAT 1200

TCGCTGGGAC TCGTGTTTTG GGAGGTGGTG CGAAGGTGCA ATATTGGGGG TCAGAACTTG 1260

GACTACCAAC TGCCATACTT TGACATGGTG CCCGATGATC CTTCCATCGA GCAAATGCGC 1320

ACAATCGTGT GTGAAAAGAA CATCCGACCA CAGAAGGAGA CGACTTGGCA TAAATATGAT 1380

ACGACGGAGC GGATGTGGAG GTTGATGCAG GAATGTTGGT ACGAGAACGG ATGTGCTCGA 1440

CTCACCGCGC TCCGCGTGAA GAAGAGCATC GCGAGGATAG AGGATGAGGA AGGAGTCAAG 1500

CATGTGTGA 1509

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++l+++igkGrygeV+++k+rge+vAvK f t+de+sw rE+eiyqt++lrhenil+fia

Q: 203   IQLQDVIGKGRYGEVFRGKWRGEDVAVKKFVTRDESSWAREAEIYQTIMLRHENILGFIA  262

         7899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k+ +++tel+lv+eyhe+gsL+dyL ++ +dv ++l+++ s+asGlahLH+eivgt

Q: 263   ADNKDVGTWTELWLVSEYHENGSLFDYLGETRIDVASMLKIVGSIASGLAHLHNEIVGTL  322

         ***********************************************************9

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  Kp iaH DlkskNilvkk++ c+iaDlGLa++++++++++d+  n++vGtkRYmaPE

Q: 323   G--KPPIAHCDLKSKNILVKKNGECAIADLGLAVRHDSSTDTIDIPPNNRVGTKRYMAPE  380

         9..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         +l+e+ln+ +f++fkraD+YslgLv+WEv++Rc+  +++  +y+lp+ ++v+ dPs+e+m

Q: 381   ILDETLNMLHFDSFKRADIYSLGLVFWEVVRRCNI-GGQNLDYQLPYFDMVPDDPSIEQM  439

         ***********************************.999*********************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         +++v+ek++rP+ +++w+k ++ + + +l++ecW++++ aRltalrvkk

Q: 440   RTIVCEKNIRPQKETTWHKYDTTERMWRLMQECWYENGCARLTALRVKKS  489

         ************************************************97

Domain Sequence
(FASTA)

IQLQDVIGKG RYGEVFRGKW RGEDVAVKKF VTRDESSWAR EAEIYQTIML RHENILGFIA 60

ADNKDVGTWT ELWLVSEYHE NGSLFDYLGE TRIDVASMLK IVGSIASGLA HLHNEIVGTL 120

GKPPIAHCDL KSKNILVKKN GECAIADLGL AVRHDSSTDT IDIPPNNRVG TKRYMAPEIL 180

DETLNMLHFD SFKRADIYSL GLVFWEVVRR CNIGGQNLDY QLPYFDMVPD DPSIEQMRTI 240

VCEKNIRPQK ETTWHKYDTT ERMWRLMQEC WYENGCARLT ALRVKKS 287

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013