EKS-CIS-00209

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00209

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKA	468.0	6.8E-141	43	297	255

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000004910

UniProt Accession

H2YHW2;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000002924	ENSCSAVP00000004911	ENSCSAVT00000004980
ENSCSAVG00000002924	ENSCSAVP00000004912	ENSCSAVT00000004981
ENSCSAVG00000002924	ENSCSAVP00000004910	ENSCSAVT00000004979
ENSCSAVG00000002924	ENSCSAVP00000004909	ENSCSAVT00000004978

Organism

Ciona savignyi

Functional Description

Protein Length

319

Protein Sequence
(FASTA)

MGNTPAKKGD QAESVKAFLA EAKEEFLKKW ENPIQNNSKL DDFERLKTLG TGSFGRVILV 60

KRKENTSFYA MKILDKQKVV KLKQVEHTLN EKKILQAINF PFLVKMDFSF KDNSNLYMVL 120

EYVIGGEMFS HLRRIGRFSE SHSRFYAAQI VLGFEYLHYL DIIYRDLKPE NLLIDQQGYI 180

QVTDFGFAKR VKGRTWTLCG TPEYLAPEII LSKGYNKAVD WWALGVLIYE MAAGYPPFFA 240

DQPIQIYEKI VSGKVRFPSH FTSELKDLLR NLLQVDLTKR FGNLKNGVAD IKGHRWFQPI 300

DWIAVYQKKL EAPFMPKFK 319

Nucleotide Sequence
(FASTA)

ATGGGCAACA CTCCTGCGAA GAAAGGGGAT CAGGCTGAAA GTGTGAAAGC CTTTTTGGCT 60

GAAGCAAAGG AAGAATTTTT GAAAAAATGG GAAAACCCCA TCCAGAACAA CTCGAAATTG 120

GATGACTTCG AGAGGTTGAA AACATTAGGA ACTGGCTCCT TTGGACGAGT TATTCTTGTC 180

AAACGCAAAG AGAATACGAG CTTCTATGCA ATGAAAATTC TTGACAAACA GAAAGTCGTC 240

AAGCTTAAGC AGGTCGAACA CACTTTAAAT GAGAAGAAGA TATTGCAAGC AATCAATTTC 300

CCTTTCTTAG TTAAAATGGA TTTCTCTTTT AAGGACAATA GTAACTTGTA CATGGTGTTG 360

GAGTATGTTA TAGGGGGGGA GATGTTTTCG CATTTAAGAA GAATTGGAAG ATTCAGTGAG 420

TCCCATTCGA GGTTCTACGC AGCACAAATC GTGCTGGGCT TCGAATACCT ACATTACCTT 480

GATATCATCT ACCGCGATCT TAAACCGGAA AACTTACTTA TCGACCAACA AGGATACATC 540

CAGGTCACTG ATTTCGGATT CGCCAAGCGA GTGAAAGGAC GAACTTGGAC ACTGTGTGGC 600

ACCCCAGAGT ACCTTGCCCC GGAGATTATT CTTAGTAAGG GTTACAACAA AGCTGTGGAT 660

TGGTGGGCGC TTGGCGTGCT GATATATGAA ATGGCAGCCG GGTACCCCCC TTTCTTCGCC 720

GACCAACCGA TTCAAATCTA TGAGAAGATT GTGTCGGGAA AGGTTCGCTT CCCGTCACAT 780

TTCACATCCG AGTTGAAGGA TTTGCTGCGG AATCTTCTAC AAGTTGATCT CACCAAGCGA 840

TTCGGCAACT TGAAGAACGG GGTGGCAGAT ATAAAGGGCC ACCGATGGTT CCAACCCATT 900

GATTGGATCG CTGTCTACCA AAAAAAGCTG GAAGCCCCAT TCATGCCCAA GTTCAAA 957

Domain Profile

S: 1     ferlktlGtGsfGrvelvrekeskkyyalkvlskekvvklkqvehvknekrvlkavefpf  60

         ferlktlGtGsfGrv lv+ ke+ ++ya+k+l+k+kvvklkqveh+ nek++l+a++fpf

Q: 43    FERLKTLGTGSFGRVILVKRKENTSFYAMKILDKQKVVKLKQVEHTLNEKKILQAINFPF  102

         799*********************************************************

S: 61    lvkllasfkdesnlylvleyveGGelfsylrkvrrfsekaarfyaaeivlaleylhsldl  120

         lvk+ +sfkd+snly+vleyv GGe+fs+lr+++rfse+++rfyaa+ivl +eylh ld+

Q: 103   LVKMDFSFKDNSNLYMVLEYVIGGEMFSHLRRIGRFSESHSRFYAAQIVLGFEYLHYLDI  162

         ************************************************************

S: 121   iyrdlkpenllldkeGyikvtdfGfakkvkdrtwtlcGtpeylapeiiqskgynkavdww  180

         iyrdlkpenll+d++Gyi+vtdfGfak+vk+rtwtlcGtpeylapeii skgynkavdww

Q: 163   IYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWW  222

         ************************************************************

S: 181   alGvliyellaGyppffddqpikiyekivsgklkfpsklssdlkdllkkllqvdltkrlg  240

         alGvliye++aGyppff+dqpi+iyekivsgk++fps+++s+lkdll++llqvdltkr+g

Q: 223   ALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSELKDLLRNLLQVDLTKRFG  282

         ************************************************************

S: 241   nlkngvedikehkwf  255

         nlkngv dik h+wf

Q: 283   NLKNGVADIKGHRWF  297

         **************9

Domain Sequence
(FASTA)

FERLKTLGTG SFGRVILVKR KENTSFYAMK ILDKQKVVKL KQVEHTLNEK KILQAINFPF 60

LVKMDFSFKD NSNLYMVLEY VIGGEMFSHL RRIGRFSESH SRFYAAQIVL GFEYLHYLDI 120

IYRDLKPENL LIDQQGYIQV TDFGFAKRVK GRTWTLCGTP EYLAPEIILS KGYNKAVDWW 180

ALGVLIYEMA AGYPPFFADQ PIQIYEKIVS GKVRFPSHFT SELKDLLRNL LQVDLTKRFG 240

NLKNGVADIK GHRWF 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013