EKS-CIS-00181

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00181

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Csk	352.1	1.3E-105	189	438	250

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000005610

UniProt Accession

H2YJW5;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.5205

Gene Synonyms/Alias

Csa.5205;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000003351	ENSCSAVP00000005610	ENSCSAVT00000005685
ENSCSAVG00000003351	ENSCSAVP00000005609	ENSCSAVT00000005684
ENSCSAVG00000003351	ENSCSAVP00000005615	ENSCSAVT00000005690
ENSCSAVG00000003351	ENSCSAVP00000005613	ENSCSAVT00000005688
ENSCSAVG00000003351	ENSCSAVP00000005614	ENSCSAVT00000005689
ENSCSAVG00000003351	ENSCSAVP00000005611	ENSCSAVT00000005686
ENSCSAVG00000003351	ENSCSAVP00000005612	ENSCSAVT00000005687

Organism

Ciona savignyi

Functional Description

Protein Length

450

Protein Sequence
(FASTA)

GTECEGIFDF NTGKKTDLQF KKGDSITVMQ RTRDPNWYKA KNEKGEQGMV PINYIVKNEA 60

HRNAVSSMFL PSWFHGKISR SAAEDLLTPR KDGLFLVRES TNYPGDYTMC VSYAGDVEHY 120

RVIFKDNKVT IDEEEYFENL TKLVEHYKID ADGLVCALSL PLVKSGGLEY SVDTEEFRRS 180

GWDIDKKDLK LGAILGKGDF GDVYEGTFKE QKVAVKSVKD RSKAAQTFLA EASVMTQGKL 240

HHKNLIQLLG VVIPRSMSND PIYVVLEFMT KGSLLEYLRS RGRAMVTSND LWKFAKDIAQ 300

GMEYLEKKQL VHRDLAARNI LISEDCTAKV SDFGLARDAS FNLQGGKFPV KWTAPEALKE 360

GKFSNKSDVW SYGITLWEMW SFGRVPYPRV PLKDLLSKVQ AGYRMDCPEK CEKVIYQLML 420

KCWLKDVSER LSFAQIVLEL DRIKSQLLPA 450

Nucleotide Sequence
(FASTA)

GGCACAGAAT GTGAGGGAAT TTTCGACTTC AACACTGGGA AGAAAACCGA TCTTCAGTTC 60

AAGAAAGGAG ATTCGATAAC AGTAATGCAG CGTACACGCG ATCCCAATTG GTACAAAGCG 120

AAGAATGAGA AAGGGGAGCA GGGGATGGTC CCAATCAACT ATATCGTTAA AAATGAAGCT 180

CACCGCAATG CCGTAAGTTC CATGTTCCTT CCTTCTTGGT TCCACGGCAA GATATCGCGC 240

TCGGCGGCCG AAGACCTCCT CACCCCCCGC AAGGACGGGT TGTTCCTGGT TAGGGAAAGT 300

ACCAACTACC CCGGGGACTA CACGATGTGT GTGAGTTACG CAGGAGACGT GGAGCATTAT 360

CGCGTCATCT TCAAAGACAA CAAAGTCACC ATTGATGAGG AAGAATATTT CGAGAATCTC 420

ACCAAACTTG TGGAGCATTA CAAGATCGAC GCAGATGGAT TGGTTTGCGC ACTGTCGCTA 480

CCACTGGTCA AGAGTGGGGG ATTGGAGTAT TCAGTTGACA CCGAGGAATT CAGGAGAAGT 540

GGGTGGGACA TCGACAAGAA AGATTTGAAA CTGGGGGCGA TTCTCGGGAA GGGGGATTTC 600

GGGGACGTGT ACGAGGGGAC GTTCAAGGAA CAGAAAGTCG CCGTGAAATC TGTGAAAGAT 660

CGATCGAAGG CTGCGCAAAC TTTCCTCGCG GAGGCCTCGG TCATGACCCA AGGCAAACTC 720

CACCACAAGA ACCTCATCCA GCTACTCGGG GTGGTGATCC CCCGATCCAT GTCCAACGAC 780

CCAATCTACG TCGTTCTAGA ATTCATGACA AAGGGCTCAT TGTTGGAGTA CCTGAGGTCA 840

AGAGGTCGCG CCATGGTCAC CAGCAACGAC CTTTGGAAAT TTGCCAAGGA TATCGCGCAA 900

GGCATGGAAT ACTTGGAGAA GAAACAACTG GTCCACCGGG ATTTAGCTGC GCGGAACATA 960

TTAATATCGG AGGATTGCAC GGCCAAGGTG TCCGACTTCG GGCTCGCACG CGATGCGTCG 1020

TTTAATCTCC AAGGAGGGAA ATTCCCCGTC AAATGGACGG CCCCGGAGGC ATTGAAGGAA 1080

GGGAAATTCT CCAACAAGTC GGACGTGTGG AGTTATGGGA TCACTTTGTG GGAAATGTGG 1140

TCGTTCGGTC GAGTACCTTA CCCTAGAGTT CCACTCAAAG ACCTGCTGAG CAAGGTACAG 1200

GCGGGATATC GTATGGATTG CCCCGAGAAA TGCGAGAAAG TGATTTACCA GTTGATGTTG 1260

AAATGTTGGC TGAAAGACGT CTCTGAAAGA CTTAGTTTCG CTCAAATCGT GCTCGAACTT 1320

GACCGCATTA AATCCCAGCT TCTTCCCGCT 1350

Domain Profile

S: 1     lklgetigkgefgdvllgeyrgekvavkvik.ndataqafldeasvmtk..lehenlvkl  57

         lklg+ +gkg+fgdv  g+++++kvavk +k    +aq+fl+easvmt+  l+h+nl++l

Q: 189   LKLGAILGKGDFGDVYEGTFKEQKVAVKSVKdRSKAAQTFLAEASVMTQgkLHHKNLIQL  248

         689999*************************445689**********95449********

S: 58    lgvileek....glylvteyvakgslvdylrsrgrallekkqllkfaldvaegmeylesk  113

         lgv++        +y+v+e+++kgsl++ylrsrgra++++++l kfa d+a+gmeyle k

Q: 249   LGVVIPRSmsndPIYVVLEFMTKGSLLEYLRSRGRAMVTSNDLWKFAKDIAQGMEYLEKK  308

         ****854322237***********************************************

S: 114   klvhrdlaarnvlvsedlvakvsdfglakeeskdldsgklpvkwtapealkekkfstksd  173

         +lvhrdlaarn+l+sed+ akvsdfgla+++s +l+ gk+pvkwtapealke+kfs+ksd

Q: 309   QLVHRDLAARNILISEDCTAKVSDFGLARDASFNLQGGKFPVKWTAPEALKEGKFSNKSD  368

         ************************************************************

S: 174   vwsfgillweifsfgrvpypriplkdvvkavekgykmeapegcppevyelmkeaweleaa  233

         vws+gi lwe++sfgrvpypr+plkd+  +v+ gy+m+ pe c   +y+lm ++w  + +

Q: 369   VWSYGITLWEMWSFGRVPYPRVPLKDLLSKVQAGYRMDCPEKCEKVIYQLMLKCWLKDVS  428

         ************************************************************

S: 234   krpsfaklke  243

         +r sfa+++

Q: 429   ERLSFAQIVL  438

         *******975

Domain Sequence
(FASTA)

LKLGAILGKG DFGDVYEGTF KEQKVAVKSV KDRSKAAQTF LAEASVMTQG KLHHKNLIQL 60

LGVVIPRSMS NDPIYVVLEF MTKGSLLEYL RSRGRAMVTS NDLWKFAKDI AQGMEYLEKK 120

QLVHRDLAAR NILISEDCTA KVSDFGLARD ASFNLQGGKF PVKWTAPEAL KEGKFSNKSD 180

VWSYGITLWE MWSFGRVPYP RVPLKDLLSK VQAGYRMDCP EKCEKVIYQL MLKCWLKDVS 240

ERLSFAQIVL 250

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR001452	; SH3_domain.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.
PF00018	; SH3_1; 1.

SMARTs

SM00252	; SH2; 1.
SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50001	; SH2; 1.
PS50002	; SH3; 1.

Prints

PR00401	; SH2DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013