EKS-CIS-00041

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00041

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	425.1	1.8E-127	65	361	297

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000005984

UniProt Accession

H2YKY2;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000003568	ENSCSAVP00000005984	ENSCSAVT00000006059

Organism

Ciona savignyi

Functional Description

Protein Length

375

Protein Sequence
(FASTA)

ESVKAFGSRL TTFELSEILD YNDIWFLGLD GKKVQGVQGA SQNCGYDDEN GSYIKVLHDH 60

MIYRYEVLEV IGKGSFGQVV KAIDHKTNTL VAIKIIRNKK RFHHQALVEV RILDALRRND 120

KDGAHNVIHM LESFYFRNHL CITFELLGMN LYELIKKNNF QGFSLPLIRR IAHALLKCLC 180

LIYKERIIHC DMKPENILIR QKGQSSIKVI DFGSSCYEHQ RVYTYIQSRF YRSPEVILGH 240

QYSMAIDMWS FGCILAELYT GYPLFPGENE VEQLACIMEV LGIPPSDYIE TAQRKRLFFD 300

SKGQPRCITN SKGRKRRPNS KDLSTAVRTS DPVFLHFLRR CLEWEPGKRM TPEEAMHHEW 360

IVEGRFQKTR GQSRH 375

Nucleotide Sequence
(FASTA)

GAATCGGTGA AAGCGTTCGG CTCCCGATTG ACCACATTCG AGTTGAGTGA GATATTGGAT 60

TACAATGATA TTTGGTTCCT GGGATTGGAT GGGAAGAAAG TGCAGGGAGT ACAAGGAGCG 120

TCACAGAACT GCGGATACGA TGACGAGAAC GGGTCTTATA TTAAGGTTCT GCATGACCAC 180

ATGATATATC GATACGAAGT GTTGGAAGTA ATTGGAAAAG GTTCATTCGG GCAAGTGGTG 240

AAAGCAATTG ACCACAAAAC TAATACTTTG GTGGCCATTA AGATTATTAG GAACAAAAAA 300

CGATTCCACC ACCAAGCACT GGTCGAAGTG AGAATACTGG ACGCATTACG TAGGAATGAT 360

AAAGATGGCG CCCACAACGT CATTCATATG CTGGAGTCAT TTTACTTTAG AAATCATTTG 420

TGCATAACCT TCGAGTTACT CGGTATGAAC CTCTACGAGC TGATCAAAAA GAACAACTTT 480

CAAGGCTTCA GTCTCCCACT TATACGAAGA ATAGCTCACG CACTGCTGAA GTGCTTGTGT 540

CTCATATACA AGGAGAGAAT CATTCATTGC GACATGAAAC CCGAGAATAT ATTAATCCGC 600

CAGAAAGGTC AAAGTTCAAT TAAAGTCATC GACTTTGGAT CAAGTTGTTA TGAACACCAA 660

CGTGTGTACA CGTACATCCA AAGTCGGTTC TATCGCTCGC CAGAGGTGAT ACTGGGTCAC 720

CAGTACAGCA TGGCTATAGA CATGTGGAGT TTCGGTTGCA TTCTGGCTGA ACTCTACACT 780

GGGTACCCGC TCTTTCCTGG GGAGAATGAA GTGGAACAAC TTGCTTGTAT CATGGAGGTG 840

CTTGGTATTC CTCCATCTGA TTACATTGAA ACTGCTCAGC GAAAACGACT CTTTTTTGAT 900

TCCAAGGGTC AACCACGTTG TATAACGAAC AGCAAGGGTC GGAAACGTCG ACCGAACTCC 960

AAGGACTTAA GTACAGCTGT GCGCACCAGT GATCCTGTGT TCCTACACTT CCTGAGGAGG 1020

TGTTTGGAAT GGGAACCAGG GAAGAGGATG ACGCCAGAGG AGGCGATGCA TCACGAGTGG 1080

ATCGTGGAAG GAAGGTTCCA GAAGACTCGT GGTCAGTCCC GTCAC 1125

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevlevigkGsfgqVvka d+kt++ vaikii+nkkrf++qa  Ev+iL++l+++dk+ +

Q: 65    YEVLEVIGKGSFGQVVKAIDHKTNTLVAIKIIRNKKRFHHQALVEVRILDALRRNDKDGA  124

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         +nv+++le+f+frnhlc++fell +nLyel+kkn+f+g+sl l+r++a+ +lk+L+l+++

Q: 125   HNVIHMLESFYFRNHLCITFELLGMNLYELIKKNNFQGFSLPLIRRIAHALLKCLCLIYK  184

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         ++iiH+D+KPeNil+ +k++s++kviDFGss++++q+ +ytyiqsrfYr+PE+ilg++y+

Q: 185   ERIIHCDMKPENILIRQKGQSSIKVIDFGSSCYEHQR-VYTYIQSRFYRSPEVILGHQYS  243

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         +aiDmWS+Gc+laEl+tG+pLfpGenev+qla+i+evlg+pp+  +e+a++++ ff++k+

Q: 244   MAIDMWSFGCILAELYTGYPLFPGENEVEQLACIMEVLGIPPSDYIETAQRKRLFFDSKG  303

         ************************************************************

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

         +p++i+++k                 +++ p+sk+l++a+++  d  f ++l+r+le++p

Q: 304   QPRCITNSK----------------GRKRRPNSKDLSTAVRTS-DPVFLHFLRRCLEWEP  346

         ***988543................233456666776666555.556*************

S: 301   akRitpkealkhpfv  315

          kR+tp+ea++h+++

Q: 347   GKRMTPEEAMHHEWI  361

         **************7

Domain Sequence
(FASTA)

YEVLEVIGKG SFGQVVKAID HKTNTLVAIK IIRNKKRFHH QALVEVRILD ALRRNDKDGA 60

HNVIHMLESF YFRNHLCITF ELLGMNLYEL IKKNNFQGFS LPLIRRIAHA LLKCLCLIYK 120

ERIIHCDMKP ENILIRQKGQ SSIKVIDFGS SCYEHQRVYT YIQSRFYRSP EVILGHQYSM 180

AIDMWSFGCI LAELYTGYPL FPGENEVEQL ACIMEVLGIP PSDYIETAQR KRLFFDSKGQ 240

PRCITNSKGR KRRPNSKDLS TAVRTSDPVF LHFLRRCLEW EPGKRMTPEE AMHHEWI 297

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013